Targeting Interleukin-1 beta to Suppress Sympathoexcitation in Hypothalamic Paraventricular Nucleus in Dahl Salt-Sensitive Hypertensive Rats

Cardiovascular Toxicology

Volumn 16, Issue 3, 2016, Pages 298-306

  Qi, Jie ^a   Zhao, Xiu Fang ^a   Yu, Xiao Jing ^a   Yi, Qiu Yue ^a   Shi, Xiao Lian ^a   Tan, Hong ^a   Fan, Xiao Yan ^a   Gao, Hong Li ^a   Yue, Li Ying ^a   Feng, Zhi Peng ^a   Kang, Yu Ming ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Hypothalamic paraventricular nucleus; Interleukin 1 beta; NLRP3; Oxidative stress; Salt sensitive hypertension

Indexed keywords

CELL PROTEIN; CRYOPYRIN; FRA LI PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; NORADRENALIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; CYBB PROTEIN, RAT; GEVOKIZUMAB; IL1B PROTEIN, RAT; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; NLRP3 PROTEIN, RAT; NOX4 PROTEIN, RAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SALT INTAKE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; HEART EXCITATION; HEART RATE; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MEAN ARTERIAL PRESSURE; MOLECULAR PATHOLOGY; NONHUMAN; NORADRENALIN BLOOD LEVEL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SYMPATHOEXCITATION; ADRENERGIC SYSTEM; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTERIAL PRESSURE; BLOOD; DAHL RAT; DISEASE MODEL; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; SALT INTAKE;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIHYPERTENSIVE AGENTS; ARTERIAL PRESSURE; DISEASE MODELS, ANIMAL; HEART RATE; HYPERTENSION; INTERLEUKIN-10; INTERLEUKIN-1BETA; MALE; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; NOREPINEPHRINE; OXIDATIVE STRESS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS, INBRED DAHL; SODIUM CHLORIDE, DIETARY; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM;

EID: 84939839373     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-015-9338-7     Document Type: Article

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