Inhibition of NF-κB activity in the hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by modulating cytokines and attenuating oxidative stress

Toxicology and Applied Pharmacology

Volumn 284, Issue 3, 2015, Pages 315-322

  Yu, Xiao Jing ^a   Zhang, Dong Mei ^c   Jia, Lin Lin ^a   Qi, Jie ^a   Song, Xin Ai ^a   Tan, Hong ^a   Cui, Wei ^f   Chen, Wensheng ^d   Zhu, Guo Qing ^e   Qin, Da Nian ^b   Kang, Yu Ming ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e NANJING MEDICAL UNIVERSITY   (China)

^f THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Cardiac hypertrophy; Hypertension; Hypothalamic paraventricular nucleus; Neurohormonal excitation; NF B

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; CYTOKINE; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; RELA PROTEIN, RAT; THIOCARBAMIC ACID DERIVATIVE; TRANSCRIPTION FACTOR RELA;

ADRENERGIC SYSTEM; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTERIAL PRESSURE; CARDIOMEGALY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; IMMUNOLOGY; METABOLISM; OXIDATIVE STRESS; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; TIME; WISTAR KYOTO RAT;

ANIMALS; ARTERIAL PRESSURE; BIOLOGICAL MARKERS; CARDIOMEGALY; CYTOKINES; DISEASE MODELS, ANIMAL; HYPERTENSION; INFLAMMATION MEDIATORS; OXIDATIVE STRESS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PYRROLIDINES; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM; THIOCARBAMATES; TIME FACTORS; TRANSCRIPTION FACTOR RELA;

EID: 84933514868     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.02.023     Document Type: Article

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