Direct Identification of Rituximab Main Isoforms and Subunit Analysis by Online Selective Comprehensive Two-Dimensional Liquid Chromatography-Mass Spectrometry

Analytical Chemistry

Volumn 87, Issue 16, 2015, Pages 8307-8315

  Stoll, Dwight R ^a   Harmes, David C ^a   Danforth, John ^a   Wagner, Elsa ^b   Guillarme, Davy ^c   Fekete, Szabolcs ^c   Beck, Alain ^b  

^a GUSTAVUS ADOLPHUS COLLEGE   (United States)

^b Centre d'Immunologie Pierre Fabre   (France)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; DESALINATION; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; SEPARATION; SOCIAL NETWORKING (ONLINE); SPECTROMETRY;

CATIONEXCHANGE CHROMATOGRAPHY (CEX); COMPREHENSIVE TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY; DIRECT IDENTIFICATIONS; MS DETECTION; PEAK CAPACITY; PROOF OF CONCEPT; REVERSE PHASE LIQUID CHROMATOGRAPHY; THERAPEUTIC MONOCLONAL ANTIBODIES;

CHROMATOGRAPHY;

ISOPROTEIN; MONOCLONAL ANTIBODY; RITUXIMAB;

CHEMICAL ANALYSIS; CHEMISTRY; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ONLINE SYSTEM; PROCEDURES;

ANTIBODIES, MONOCLONAL; CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY, LIQUID; MASS SPECTROMETRY; ONLINE SYSTEMS; PROTEIN ISOFORMS; RITUXIMAB;

EID: 84939785399     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/acs.analchem.5b01578     Document Type: Article

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