-
1
-
-
0037318233
-
Using amino acid analysis to determine absorptivity constants
-
Anders, J.C., B.F. Parten, G.E. Petrie, R.L. Marlowe, and J.E. McEntire. 2003. Using amino acid analysis to determine absorptivity constants. BioPharm. Int. 16:30-37.
-
(2003)
BioPharm. Int
, vol.16
, pp. 30-37
-
-
Anders, J.C.1
Parten, B.F.2
Petrie, G.E.3
Marlowe, R.L.4
McEntire, J.E.5
-
2
-
-
0035943486
-
Affinity-reversed phase liquid chromatography assay to quantitate recombinant antibodies and antibody fragments in fermentation broth
-
Battersby, J.E., B. Snedecor, C. Chen, K.M. Champion, L. Riddle, and M. Vanderlaan. 2001. Affinity-reversed phase liquid chromatography assay to quantitate recombinant antibodies and antibody fragments in fermentation broth. J. Chromatogr. A 927:61-76.
-
(2001)
J. Chromatogr. A
, vol.927
, pp. 61-76
-
-
Battersby, J.E.1
Snedecor, B.2
Chen, C.3
Champion, K.M.4
Riddle, L.5
Vanderlaan, M.6
-
3
-
-
0029164230
-
Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid
-
Bigge, J.C., T.P. Patel, J.A. Bruce, P.N. Goulding, S.M. Charles, and R.B. Parekh. 1995. Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. Anal. Biochem. 230(2):229-238.
-
(1995)
Anal. Biochem
, vol.230
, Issue.2
, pp. 229-238
-
-
Bigge, J.C.1
Patel, T.P.2
Bruce, J.A.3
Goulding, P.N.4
Charles, S.M.5
Parekh, R.B.6
-
4
-
-
0030022071
-
Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity
-
Cacia, J., R. Keck, L.G. Presta, and J. Frenz. 1996. Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity. Biochemistry 35:1897-1903.
-
(1996)
Biochemistry
, vol.35
, pp. 1897-1903
-
-
Cacia, J.1
Keck, R.2
Presta, L.G.3
Frenz, J.4
-
5
-
-
33645697563
-
Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies
-
Chelius, D., et al. 2006. Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies. Anal. Chem. 78(7):2370-2376.
-
(2006)
Anal. Chem
, vol.78
, Issue.7
, pp. 2370-2376
-
-
Chelius, D.1
-
6
-
-
8344224534
-
Characterizing biological products and assessing comparability following manufacturing changes
-
Chirino, A.J., and Mire-Sluis, A. 2004. Characterizing biological products and assessing comparability following manufacturing changes. Nature Biotechnol. 22:1383-1391.
-
(2004)
Nature Biotechnol
, vol.22
, pp. 1383-1391
-
-
Chirino, A.J.1
Mire-Sluis, A.2
-
7
-
-
34247346055
-
Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody
-
Chumsae, C., et al. 2007. Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody. J. Chromatogr. B 850(1-2):285-294.
-
(2007)
J. Chromatogr. B
, vol.850
, Issue.1-2
, pp. 285-294
-
-
Chumsae, C.1
-
8
-
-
34250182367
-
Beta-elimination and peptide bond hydrolysis: Two distinct mechanisms of human IgG1 hinge fragmentation upon storage
-
Cohen, S.L., C. Price, and J. Vlasak. 2007. Beta-elimination and peptide bond hydrolysis: Two distinct mechanisms of human IgG1 hinge fragmentation upon storage. J. Am. Chem. Soc. 129:6976-6977.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 6976-6977
-
-
Cohen, S.L.1
Price, C.2
Vlasak, J.3
-
9
-
-
14744289246
-
Non-enzymatic hinge region fragmentation of antibodies in solution
-
Cordoba, A.J., B.J. Shyong, D. Breen, and R.J.J. Harris. 2005. Non-enzymatic hinge region fragmentation of antibodies in solution. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 818:115-121.
-
(2005)
Chromatogr. B Analyt. Technol. Biomed. Life Sci
, vol.818
, pp. 115-121
-
-
Cordoba, A.J.1
Shyong, B.J.2
Breen, D.3
Harris, R.J.J.4
-
10
-
-
0032488375
-
Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells
-
Goldman, M.H., D.C. James, M. Rendall, A.P. Ison, M. Hoare, and A.T. Bull. 1998. Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells. Biotechnol. Bioeng. 60(5):596-607.
-
(1998)
Biotechnol. Bioeng
, vol.60
, Issue.5
, pp. 596-607
-
-
Goldman, M.H.1
James, D.C.2
Rendall, M.3
Ison, A.P.4
Hoare, M.5
Bull, A.T.6
-
11
-
-
0036882287
-
Protein disulfide bond determination by mass spectrometry
-
Gorman, J.J., T.P. Wallis, and J.J. Pitt. 2002. Protein disulfide bond determination by mass spectrometry. Mass Spectrometry Rev. 21(3):183-216.
-
(2002)
Mass Spectrometry Rev
, vol.21
, Issue.3
, pp. 183-216
-
-
Gorman, J.J.1
Wallis, T.P.2
Pitt, J.J.3
-
12
-
-
0027445423
-
Assessing genetic heterogeneity in production cell lines: Detection by peptide mapping of a low level Tyr to Gln sequence variant in a recombinant antibody
-
Harris, R.J., A.A. Murnane, S.L. Utter, K.L. Wagner, E.T. Cox, G. Polastri, J.C. Helder, and M.B. Sliwkowski. 1993. Assessing genetic heterogeneity in production cell lines: Detection by peptide mapping of a low level Tyr to Gln sequence variant in a recombinant antibody. Biotechnology 11:1293-1297.
-
(1993)
Biotechnology
, vol.11
, pp. 1293-1297
-
-
Harris, R.J.1
Murnane, A.A.2
Utter, S.L.3
Wagner, K.L.4
Cox, E.T.5
Polastri, G.6
Helder, J.C.7
Sliwkowski, M.B.8
-
13
-
-
3843058933
-
Commercial manufacturing scale formulation and analytical characterization of therapeutic recombinant antibodies
-
Harris, R.J., S.J. Shire, and C. Winter. 2004. Commercial manufacturing scale formulation and analytical characterization of therapeutic recombinant antibodies. Drug Dev. Res. 61:17.
-
(2004)
Drug Dev. Res
, vol.61
, pp. 17
-
-
Harris, R.J.1
Shire, S.J.2
Winter, C.3
-
14
-
-
0030338341
-
Characterization, formulation, and stability of Neupogen (filgras-tim), a recombinant human granulocyte colony-stimulating factor
-
In, ed. R. Pearlman and Y.J. Wang,, New York: Plenum Press.
-
Herman, A.C., T.C. Boone, and H.S. Lu. 1996. Characterization, formulation, and stability of Neupogen (filgras-tim), a recombinant human granulocyte colony-stimulating factor. In Formulation, Characterization, and Stability of Protein Drugs, ed. R. Pearlman and Y.J. Wang, 303-328. New York: Plenum Press.
-
(1996)
Formulation, Characterization, and Stability of Protein Drugs
, pp. 303-328
-
-
Herman, A.C.1
Boone, T.C.2
Lu, H.S.3
-
15
-
-
27744566590
-
Determination of picomolar equilibrium dissociation constants in solution by enzyme-linked immunosorbent assay with fluorescence detection
-
High, K., Y. Meng, M. Washabaugh, and Q. Zhao. 2005. Determination of picomolar equilibrium dissociation constants in solution by enzyme-linked immunosorbent assay with fluorescence detection. Anal. Biochem 347:159-161.
-
(2005)
Anal. Biochem
, vol.347
, pp. 159-161
-
-
High, K.1
Meng, Y.2
Washabaugh, M.3
Zhao, Q.4
-
16
-
-
0034802701
-
Glycosylation of human IgG antibodies: Relevance to theraputic applications
-
Jefferis, R. 2001. Glycosylation of human IgG antibodies: Relevance to theraputic applications. BioPharm (International) 14:19-26.
-
(2001)
BioPharm (International)
, vol.14
, pp. 19-26
-
-
Jefferis, R.1
-
17
-
-
0034584873
-
The use of circular dichroism in the investigation of protein structure and function
-
Kelly, S.M., and N.C. Price. 2000. The use of circular dichroism in the investigation of protein structure and function. Curr. Protein Pept. Sci. 1:349-384.
-
(2000)
Curr. Protein Pept. Sci
, vol.1
, pp. 349-384
-
-
Kelly, S.M.1
Price, N.C.2
-
18
-
-
32344449790
-
Optimization of humanized IgGs in glycoengineered Pichia pastoris
-
Li, H., N. Sethuraman, T.A. Stadheim, et al. 2006. Optimization of humanized IgGs in glycoengineered Pichia pastoris. Nature Biotechnol. 24(2):210-215.
-
(2006)
Nature Biotechnol
, vol.24
, Issue.2
, pp. 210-215
-
-
Li, H.1
Sethuraman, N.2
Stadheim, T.A.3
-
19
-
-
40649109261
-
Glycosylation profiling of atherapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer
-
Lim, A., A. Reed-Bogan, and B.J. Harmon. 2008. Glycosylation profiling of atherapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer. Anal. Biochem. 375(2):163-172.
-
(2008)
Anal. Biochem
, vol.375
, Issue.2
, pp. 163-172
-
-
Lim, A.1
Reed-Bogan, A.2
Harmon, B.J.3
-
20
-
-
33747099227
-
Effect of posttranslational modifications on the thermal stability of a recombinant monoclonal antibody
-
Liu, H., et al. 2006. Effect of posttranslational modifications on the thermal stability of a recombinant monoclonal antibody. Immunol. Lett. 106(2):144-153.
-
(2006)
Immunol. Lett
, vol.106
, Issue.2
, pp. 144-153
-
-
Liu, H.1
-
21
-
-
52449112071
-
Heterogeneity of monoclonal antibodies
-
Liu, H., D. Faldu, C. Chumsae, and J. Sun. 2008. Heterogeneity of monoclonal antibodies. J. Pharm. Sci. 97(7):2426-2447.
-
(2008)
J. Pharm. Sci
, vol.97
, Issue.7
, pp. 2426-2447
-
-
Liu, H.1
Faldu, D.2
Chumsae, C.3
Sun, J.4
-
22
-
-
34047270107
-
A role for protein misfolding in immunogenicity of biopharmaceuticals
-
Maas, C., et al. 2007. A role for protein misfolding in immunogenicity of biopharmaceuticals. J. Biol. Chem 282(4):2229-2236.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.4
, pp. 2229-2236
-
-
Maas, C.1
-
23
-
-
84891018017
-
The continuing role of amino acid analysis in a biotechnology laboratory
-
In Amino Acid Analysis Protocols, ed. C. Cooper, N. Packer, and K. Williams, 9-30., no. 159. Totowa, NJ: Humana Press.
-
Macchi, F.D., F.J. Shen, R.G. Keck, and R.J. Harris. 2001. The continuing role of amino acid analysis in a biotechnology laboratory. In Amino Acid Analysis Protocols, ed. C. Cooper, N. Packer, and K. Williams, 9-30. Methods in Molecular Biology no. 159. Totowa, NJ: Humana Press.
-
(2001)
Methods in Molecular Biology
-
-
Macchi, F.D.1
Shen, F.J.2
Keck, R.G.3
Harris, R.J.4
-
24
-
-
25444513733
-
Enhanced sensitivity and precision in an enzyme-linked immunosorbent assay with fluorogenic substrates compared with commonly used chromogenic substrates
-
Meng, Y., K. High, J. Antonello, M. Washabaugh, and Q. Zhao. 2005. Enhanced sensitivity and precision in an enzyme-linked immunosorbent assay with fluorogenic substrates compared with commonly used chromogenic substrates. Anal. Biochem. 345:227-236.
-
(2005)
Anal. Biochem
, vol.345
, pp. 227-236
-
-
Meng, Y.1
High, K.2
Antonello, J.3
Washabaugh, M.4
Zhao, Q.5
-
25
-
-
1242317024
-
Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgammaRIIIa
-
Okazaki, A., E. Shoji-Hosaka, K. Nakamura, et al. 2004. Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgammaRIIIa. J. Mol. Biol. 336(5): 1239-1249.
-
(2004)
J. Mol. Biol
, vol.336
, Issue.5
, pp. 1239-1249
-
-
Okazaki, A.1
Shoji-Hosaka, E.2
Nakamura, K.3
-
26
-
-
0028871804
-
How to measure and predict the molar absorption coefficient of a protein
-
Pace, C.N., et al. 1995. How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 4(11):2411-2423.
-
(1995)
Protein Sci
, vol.4
, Issue.11
, pp. 2411-2423
-
-
Pace, C.N.1
-
27
-
-
0031799347
-
A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionization time-of-flight mass spectro-metric analysis
-
Papac, D.I., J.B. Briggs, E.T. Chin, and A.J. Jones. 1998. A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionization time-of-flight mass spectro-metric analysis. Glycobiology 8(5):445-454.
-
(1998)
Glycobiology
, vol.8
, Issue.5
, pp. 445-454
-
-
Papac, D.I.1
Briggs, J.B.2
Chin, E.T.3
Jones, A.J.4
-
28
-
-
0027791511
-
Orthoclone OKT3. Chemical mechanisms and functional effects of degradation of a therapeutic antibody
-
In, ed. Y.J. Wang and R. Pearlman,, New York: Plenum Press.
-
Rao, P.E., and D.J. Kroon. 1993. Orthoclone OKT3. Chemical mechanisms and functional effects of degradation of a therapeutic antibody. In Stability and Characterization of Protein and Peptide Drugs: Case Histories, ed. Y.J. Wang and R. Pearlman, 135-158. New York: Plenum Press.
-
(1993)
Stability and Characterization of Protein and Peptide Drugs: Case Histories
, pp. 135-158
-
-
Rao, P.E.1
Kroon, D.J.2
-
29
-
-
0018416496
-
Ellman's reagent: 5,5'-dithiobis(2-nitrobenzoic acid): A reex-amination
-
Riddles, P.W., R.L. Blakely, and B. Zerner. 1979. Ellman's reagent: 5,5'-dithiobis(2-nitrobenzoic acid): A reex-amination. Anal. Biochem. 94:75-81.
-
(1979)
Anal. Biochem
, vol.94
, pp. 75-81
-
-
Riddles, P.W.1
Blakely, R.L.2
Zerner, B.3
-
30
-
-
0024801675
-
Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation
-
Rothman, R.J., B. Perussia, D. Herlyn, and L. Warren. 1989. Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation. Mol. Immunol. 26(12):1113-1123.
-
(1989)
Mol. Immunol
, vol.26
, Issue.12
, pp. 1113-1123
-
-
Rothman, R.J.1
Perussia, B.2
Herlyn, D.3
Warren, L.4
-
31
-
-
77957062488
-
The application of tert-butylhydroperoxide oxidation to study sites of potential methionine oxidation in a recombinant antibody
-
In, ed. D. Marshak,, San Diego: Academic Press.
-
Shen, F.J., M.Y. Kwong, R.G. Keck, and R.J. Harris. 1996. The application of tert-butylhydroperoxide oxidation to study sites of potential methionine oxidation in a recombinant antibody. In Techniques in Protein Chemistry, vol. 7, ed. D. Marshak, 275-284. San Diego: Academic Press.
-
(1996)
Techniques in Protein Chemistry
, vol.7
, pp. 275-284
-
-
Shen, F.J.1
Kwong, M.Y.2
Keck, R.G.3
Harris, R.J.4
-
32
-
-
0037178791
-
Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity
-
Shields, R.L., J. Lai, R. Keck, et al. 2002. Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity. J. Biol. Chem. 277(30):26733-26740.
-
(2002)
J. Biol. Chem
, vol.277
, Issue.30
, pp. 26733-26740
-
-
Shields, R.L.1
Lai, J.2
Keck, R.3
-
33
-
-
34248545257
-
Applications of mass spectrometry for the structural characterization of recombinant protein pharmaceuticals
-
Srebalus Barnes, C.A., and A. Lim. 2007. Applications of mass spectrometry for the structural characterization of recombinant protein pharmaceuticals. Mass Spectrometry Rev. 26(3):370-388.
-
(2007)
Mass Spectrometry Rev
, vol.26
, Issue.3
, pp. 370-388
-
-
Srebalus Barnes, C.A.1
Lim, A.2
-
34
-
-
0022003140
-
Deglycosylation of asparagine-linked glycans by peptide: N-glycosidase F
-
Tarentino, A.L., C.M. Gomez, and T.H. Plummer, Jr. 1985. Deglycosylation of asparagine-linked glycans by peptide: N-glycosidase F. Biochemistry 24(17):4665-4671.
-
(1985)
Biochemistry
, vol.24
, Issue.17
, pp. 4665-4671
-
-
Tarentino, A.L.1
Gomez, C.M.2
Plummer Jr., T.H.3
-
35
-
-
20944441421
-
Characterization of a novel modification to monoclonal antibodies: Thioether cross-link of heavy and light chains
-
Tous, G.I., Z. Wei, J. Feng, S. Bilbulian, S. Bowen, J. Smith, R. Strouse, P. McGeehan, J. Casas-Finet, and M.A. Schenerman. 2005. Characterization of a novel modification to monoclonal antibodies: Thioether cross-link of heavy and light chains. Anal. Chem. 77:2675-2682.
-
(2005)
Anal. Chem
, vol.77
, pp. 2675-2682
-
-
Tous, G.I.1
Wei, Z.2
Feng, J.3
Bilbulian, S.4
Bowen, S.5
Smith, J.6
Strouse, R.7
McGeehan, P.8
Casas-Finet, J.9
Schenerman, M.A.10
-
36
-
-
0033585877
-
Variant antibody identification by peptide mapping
-
Wan, M., F.Y. Shiau, W. Gordon, and G. Wang. 1999. Variant antibody identification by peptide mapping. Biotechnol. Bioeng. 62:485-488.
-
(1999)
Biotechnol. Bioeng
, vol.62
, pp. 485-488
-
-
Wan, M.1
Shiau, F.Y.2
Gordon, W.3
Wang, G.4
-
37
-
-
0028566966
-
Analysis of carbohydrates on IgG preparations
-
Weitzhandler, M., M. Hardy, M.S. Co, and N. Avdalovic. 1994. Analysis of carbohydrates on IgG preparations. J. Pharm. Sci. 83(12):1670-1675.
-
(1994)
J. Pharm. Sci
, vol.83
, Issue.12
, pp. 1670-1675
-
-
Weitzhandler, M.1
Hardy, M.2
Co, M.S.3
Avdalovic, N.4
-
38
-
-
84891021356
-
Evaluating the Disulfide Map of a Recombinant Membrane Protein by LC/MS/MS
-
(54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA.)
-
Wenger, M., P. DePhillips, and L. Chen. 2006. Evaluating the Disulfide Map of a Recombinant Membrane Protein by LC/MS/MS. (54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, WA.)
-
(2006)
-
-
Wenger, M.1
DePhillips, P.2
Chen, L.3
-
39
-
-
0031033895
-
Effect of glycosylation on antibody function: Implications for genetic engineering
-
Wright, A., and S.L. Morrison. 1997. Effect of glycosylation on antibody function: Implications for genetic engineering. Trends Biotechnol. 15(1):26-32.
-
(1997)
Trends Biotechnol
, vol.15
, Issue.1
, pp. 26-32
-
-
Wright, A.1
Morrison, S.L.2
-
40
-
-
0035988060
-
Free sulfhydryl in recombinant monoclonal antibodies
-
Zhang, W., and M.J. Czupryn. 2002. Free sulfhydryl in recombinant monoclonal antibodies. Biotechnol. Prog. 18:509-513.
-
(2002)
Biotechnol. Prog
, vol.18
, pp. 509-513
-
-
Zhang, W.1
Czupryn, M.J.2
-
41
-
-
0036901746
-
Complete disulfide bond assignment of a recombinant immunoglobulin G4 monoclonal antibody
-
Zhang, W., L.A. Marzilli, J.C. Rouse, and M.J. Czupryn. 2002. Complete disulfide bond assignment of a recombinant immunoglobulin G4 monoclonal antibody. Anal. Biochem. 311(1):1-9.
-
(2002)
Anal. Biochem
, vol.311
, Issue.1
, pp. 1-9
-
-
Zhang, W.1
Marzilli, L.A.2
Rouse, J.C.3
Czupryn, M.J.4
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