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Analytical Chemistry

Volumn 81, Issue 21, 2009, Pages 8846-8857

Multiproduct high-resolution monoclonal antibody charge variant separations by pH gradient ion-exchange chromatography

(2) Farnan, Dell a Moreno, G Tony a

a GENENTECH INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY INDUSTRY; BUFFER COMPONENTS; BUFFER COMPOSITION; CATION EXCHANGES; CHARGE HETEROGENEITY; COLUMN LENGTHS; DIRECT ANALYSIS; HIGH RESOLUTION; HIGH THROUGHPUT; IN-PROCESS; ION EXCHANGE SEPARATION; ION-EXCHANGE CHROMATOGRAPHY; ION-EXCHANGE METHODS; MATRIX; MULTI-PRODUCTS; OPERATIONAL ASPECTS; PEAK CAPACITY; PH GRADIENTS; RESOLVING POWER; ROBUST METHODS; SAMPLE MATRIX;

ALLERGIES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ION EXCHANGERS; IONIC STRENGTH; MERGERS AND ACQUISITIONS; MONOCLONAL ANTIBODIES; OPTICAL RESOLVING POWER; OPTIMIZATION; PH EFFECTS; SEPARATION; SURFACE PLASMON RESONANCE;

ION EXCHANGE;

BUFFER; MONOCLONAL ANTIBODY;

ARTICLE; CATION EXCHANGE; CONTROLLED STUDY; ELUTION; HIGH THROUGHPUT SCREENING; ION EXCHANGE; ION PAIR CHROMATOGRAPHY; IONIC STRENGTH; OPTICAL RESOLUTION; PH; PUMP; SEPARATION TECHNIQUE;

ANTIBODIES, MONOCLONAL; BUFFERS; CHROMATOGRAPHY, ION EXCHANGE; PROTON-MOTIVE FORCE;

EID: 70350630277 PISSN: 00032700 EISSN: None Source Type: Journal
DOI: 10.1021/ac901408j Document Type: Article

Times cited : (93)

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