Engineering Giardia lamblia trimethylguanosine synthase (GlaTgs2) to transfer non-natural modifications to the RNA 5'-cap

Protein Engineering, Design and Selection

Volumn 28, Issue 6, 2014, Pages 179-186

  Holstein, Josephin Marie ^a   Stummer, Daniela ^a   Rentmeister, Andrea ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

5' cap; AdoMet analog; Giardia intestinalis; Giardia lamblia; trimethylguanosine synthase

Indexed keywords

AMINO ACIDS; ENZYMES; PROTOZOA;

5'-CAP; ADOMET ANALOG; GIARDIA INTESTINALIS; GIARDIA LAMBLIA; SYNTHASES;

CATALYST ACTIVITY;

S ADENOSYLMETHIONINE; SYNTHETASE; TRIMETHYLGUANOSINE SYNTHASE; UNCLASSIFIED DRUG; ALANINE; METHYLTRANSFERASE; PROTOZOAL PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENE MUTATION; GIARDIA INTESTINALIS; INDEL MUTATION; MELTING POINT; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN MODIFICATION; SITE DIRECTED MUTAGENESIS; TEMPERATURE MEASUREMENT; THERMOSTABILITY; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; GENETICS; HEAT; METABOLISM; MUTATION;

EUKARYOTA; GIARDIA INTESTINALIS; HOMO SAPIENS;

ALANINE; ENZYME STABILITY; GIARDIA LAMBLIA; HOT TEMPERATURE; METHYLTRANSFERASES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTOZOAN PROTEINS;

EID: 84939542875     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzv011     Document Type: Article

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