The TbMTr1 spliced leader RNA cap 1 2′-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity

Journal of Biological Chemistry

Volumn 283, Issue 6, 2008, Pages 3161-3172

  Mittra, Bidyottam ^a   Zamudio, Jesse R ^a   Bujnicki, Janusz M ^b,c   Stepinski, Janusz ^d   Darzynkiewicz, Edward ^d   Campbell, David A ^a,e   Sturm, Nancy R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^c ADAM MICKIEWICZ UNIVERSITY   (Poland)

^d UNIVERSITY OF WARSAW   (Poland)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; ENZYMES; METHYLATION; MODULATION; NUCLEOTIDES; POLYMERS; RNA; SUBSTRATES; TRANSCRIPTION;

BIOCHEMICAL PROPERTIES; CATALYTIC CORES; GUANOSINE; HYPERMETHYLATION; METAZOA; METHYL TRANSFERASES; METHYLTRANSFERASE ACTIVITIES; NUCLEAR RNAS; PH RANGES; PROTOZOAN TRYPANOSOMA; RNA POLYMERASE II; RNA POLYMERASE III; SUBSTRATE RECOGNITIONS; SUBSTRATE SPECIFICITIES; TRYPANOSOMA BRUCEI;

NUCLEIC ACIDS;

ASPARTIC ACID; DNA DIRECTED RNA POLYMERASE III; GLUTAMIC ACID; GUANOSINE; LYSINE; MAGNESIUM ION; METHYLTRANSFERASE; RECOMBINANT ENZYME; RIBOSE; RNA POLYMERASE II; TBMTR1 ENZYME; UNCLASSIFIED DRUG; CAPPED RNA; NUCLEOTIDE; PROTOZOAL RNA; RNA 2' O METHYLTRANSFERASE; RNA 2'-O-METHYLTRANSFERASE; SMALL NUCLEAR RNA; SPLICED LEADER RNA; U1 SMALL NUCLEAR RNA;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; RNA CAPPING; RNA METHYLATION; TRYPANOSOMA BRUCEI; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; MOLECULAR GENETICS; RNA SPLICING; SEQUENCE HOMOLOGY; TRANS SPLICING;

EUKARYOTA; KINETOPLASTIDA; METAZOA; PROTOZOA; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; RNA CAPS; RNA SPLICING; RNA, PROTOZOAN; RNA, SMALL NUCLEAR; RNA, SPLICED LEADER; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TRANS-SPLICING; TRYPANOSOMA BRUCEI BRUCEI;

EID: 41249089761     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707367200     Document Type: Article

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