-
1
-
-
78651080914
-
Uncovering the human methyltransferasome
-
PMID:20930037
-
Petrossian TC, Clarke SG. Uncovering the human methyltransferasome. Mol Cell Proteomics 2011; 10:110:976; PMID:20930037.
-
(2011)
Mol Cell Proteomics
, vol.10
-
-
Petrossian, T.C.1
Clarke, S.G.2
-
2
-
-
78751470921
-
Structure and function of mammalian DNA methyltransferases
-
PMID:21243710
-
Jurkowska RZ, Jurkowski TP, Jeltsch A. Structure and function of mammalian DNA methyltransferases. Chembiochem 2011; 12:206-22; PMID:21243710; http://dx.doi.org/10.1002/cbic.201000195.
-
(2011)
Chembiochem
, vol.12
, pp. 206-222
-
-
Jurkowska, R.Z.1
Jurkowski, T.P.2
Jeltsch, A.3
-
3
-
-
69949148388
-
Protein methyltransferases as a target class for drug discovery
-
PMID:19721445
-
Copeland RA, Solomon ME, Richon VM. Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov 2009; 8:724-32; PMID:19721445; http://dx.doi.org/10.1038/nrd2974.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 724-732
-
-
Copeland, R.A.1
Solomon, M.E.2
Richon, V.M.3
-
4
-
-
0029926820
-
S-Adenosylmethionine and methylation
-
PMID:8647346
-
Chiang PK, Gordon RK, Tal J, Zeng GC, Doctor BP, Pardhasaradhi K, et al. S-Adenosylmethionine and methylation. FASEB J 1996; 10:471-80; PMID:8647346.
-
(1996)
FASEB J
, vol.10
, pp. 471-480
-
-
Chiang, P.K.1
Gordon, R.K.2
Tal, J.3
Zeng, G.C.4
Doctor, B.P.5
Pardhasaradhi, K.6
-
5
-
-
77957371299
-
Plant flavonoid O-methyltransferases: Substrate specificity and application
-
Kim BG, Sung SH, Chong Y, Lim Y, Ahn JH. Plant flavonoid O-methyltransferases: substrate specificity and application. J Plant Biol 2010; 53:321-9; http://dx.doi.org/10.1007/s12374-010-9126-7.
-
(2010)
J Plant Biol
, vol.53
, pp. 321-329
-
-
Kim, B.G.1
Sung, S.H.2
Chong, Y.3
Lim, Y.4
Ahn, J.H.5
-
6
-
-
25144483567
-
Occurrence of methylated purine bases in yeast ribonucleic acid
-
PMID:13525389
-
Adler M, Weissmann B, Gutman AB. Occurrence of methylated purine bases in yeast ribonucleic acid. J Biol Chem 1958; 230:717-23; PMID:13525389.
-
(1958)
J Biol Chem
, vol.230
, pp. 717-723
-
-
Adler, M.1
Weissmann, B.2
Gutman, A.B.3
-
7
-
-
0010742202
-
A new enzyme of RNA synthesis: RNA methylase
-
PMID:13893516
-
Fleissner E, Borek E. A new enzyme of RNA synthesis: RNA methylase. Proc Natl Acad Sci USA 1962; 48:1199-203; PMID:13893516; http://dx.doi.org/10.1073/ pnas.48.7.1199.
-
(1962)
Proc Natl Acad Sci USA
, vol.48
, pp. 1199-1203
-
-
Fleissner, E.1
Borek, E.2
-
9
-
-
0032052242
-
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA
-
PMID:9512533
-
Helm M, Brulé H, Degoul F, Cepanec C, Leroux JP, Giegé R, et al. The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA. Nucleic Acids Res 1998; 26:1636-43; PMID:9512533; http://dx.doi.org/10.1093/nar/26.7.1636.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1636-1643
-
-
Helm, M.1
Brulé, H.2
Degoul, F.3
Cepanec, C.4
Leroux, J.P.5
Giegé, R.6
-
10
-
-
0037084222
-
RNA two-state conformation equilibria and the effect of nucleobase methylation
-
Höbartner C, Ebert MO, Jaun B, Micura R. RNA two-state conformation equilibria and the effect of nucleobase methylation. Angew Chem Int Ed Engl 2002; 41:605-9; http://dx.doi. org/10.1002/1521-3773(20020215)41:4<605:: AIDANIE605> 3.0.CO;2-1.
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 605-609
-
-
Höbartner, C.1
Ebert, M.O.2
Jaun, B.3
Micura, R.4
-
11
-
-
0035476599
-
Methylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion
-
PMID:11574682
-
Micura R, Pils W, Höbartner C, Grubmayr K, Ebert MO, Jaun B. Methylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion. Nucleic Acids Res 2001; 29:3997-4005; PMID:11574682.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 3997-4005
-
-
Micura, R.1
Pils, W.2
Höbartner, C.3
Grubmayr, K.4
Ebert, M.O.5
Jaun, B.6
-
12
-
-
77950476036
-
5-methylcytosine in RNA: Detection, enzymatic formation and biological functions
-
PMID:20007150
-
Motorin Y, Lyko F, Helm M. 5-methylcytosine in RNA: detection, enzymatic formation and biological functions. Nucleic Acids Res 2010; 38:1415-30; PMID:20007150; http://dx.doi.org/10.1093/nar/gkp1117.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 1415-1430
-
-
Motorin, Y.1
Lyko, F.2
Helm, M.3
-
14
-
-
0028179047
-
Retention and 5′ cap trimethylation of U3 snRNA in the nucleus
-
PMID:8178154
-
Terns MP, Dahlberg JE. Retention and 5′ cap trimethylation of U3 snRNA in the nucleus. Science 1994; 264:959-61; PMID:8178154; http://dx.doi.org/10.1126/science.8178154.
-
(1994)
Science
, vol.264
, pp. 959-961
-
-
Terns, M.P.1
Dahlberg, J.E.2
-
15
-
-
0035964208
-
Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function
-
PMID:11517327
-
Zhu YJ, Qi C, Cao WQ, Yeldandi AV, Rao MS, Reddy JK. Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function. Proc Natl Acad Sci USA 2001; 98:10380-5; PMID:11517327; http://dx.doi.org/10.1073/ pnas.181347498.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10380-10385
-
-
Zhu, Y.J.1
Qi, C.2
Cao, W.Q.3
Yeldandi, A.V.4
Rao, M.S.5
Reddy, J.K.6
-
16
-
-
0036238278
-
Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus
-
PMID:11983179
-
Mouaikel J, Verheggen C, Bertrand E, Tazi J, BordonnéR. Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell 2002; 9:891-901; PMID:11983179; http://dx.doi.org/10.1016/S1097-2765(02)00484-7.
-
(2002)
Mol Cell
, vol.9
, pp. 891-901
-
-
Mouaikel, J.1
Verheggen, C.2
Bertrand, E.3
Tazi, J.4
Bordonné, R.5
-
17
-
-
0042591787
-
Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron
-
PMID:12776181
-
Mouaikel J, Narayanan U, Verheggen C, Matera AG, Bertrand E, Tazi J, et al. Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron. EMBO Rep 2003; 4:616-22; PMID:12776181; http://dx.doi.org/10.1038/sj.embor.embor863.
-
(2003)
EMBO Rep
, vol.4
, pp. 616-622
-
-
Mouaikel, J.1
Narayanan, U.2
Verheggen, C.3
Matera, A.G.4
Bertrand, E.5
Tazi, J.6
-
18
-
-
17344384999
-
Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus
-
PMID:12943661
-
Enünlü I, Pápai G, Cserpán I, Udvardy A, Jeang KT, Boros I. Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus. Biochem Biophys Res Commun 2003; 309:44-51; PMID:12943661; http://dx.doi.org/10.1016/S0006-291X(03)01514-6.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 44-51
-
-
Enünlü, I.1
Pápai, G.2
Cserpán, I.3
Udvardy, A.4
Jeang, K.T.5
Boros, I.6
-
20
-
-
0344998114
-
A new assay of guanidinoacetate methyltransferase
-
PMID:14496496
-
Salvatore F, Schlenk F. A new assay of guanidinoacetate methyltransferase. Biochim Biophys Acta 1962; 59:700-2; PMID:14496496; http://dx.doi.org/10.1016/0006-3002(62)90650-9.
-
(1962)
Biochim Biophys Acta
, vol.59
, pp. 700-702
-
-
Salvatore, F.1
Schlenk, F.2
-
21
-
-
25444482810
-
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2)
-
PMID:16046409
-
Hausmann S, Shuman S. Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2). J Biol Chem 2005; 280:32101-6; PMID:16046409; http://dx.doi.org/10.1074/jbc.M506438200.
-
(2005)
J Biol Chem
, vol.280
, pp. 32101-32106
-
-
Hausmann, S.1
Shuman, S.2
-
22
-
-
62549106264
-
Scintillation proximity assay for measurement of RNA methylation
-
PMID:19181706
-
Baker MR, Zarubica T, Wright HT, Rife JP. Scintillation proximity assay for measurement of RNA methylation. Nucleic Acids Res 2009; 37:32; PMID:19181706; http://dx.doi.org/10.1093/nar/gkn1038.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 32
-
-
Baker, M.R.1
Zarubica, T.2
Wright, H.T.3
Rife, J.P.4
-
23
-
-
67651159060
-
Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1
-
PMID:19386620
-
Monecke T, Dickmanns A, Ficner R. Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1. Nucleic Acids Res 2009; 37:3865-77; PMID:19386620; http://dx.doi.org/10.1093/nar/gkp249.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 3865-3877
-
-
Monecke, T.1
Dickmanns, A.2
Ficner, R.3
-
24
-
-
0842303035
-
An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases
-
PMID:14769341
-
Hendricks CL, Ross JR, Pichersky E, Noel JP, Zhou ZS. An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases. Anal Biochem 2004; 326:100-5; PMID:14769341; http://dx.doi.org/10.1016/j.ab.2003.11. 014.
-
(2004)
Anal Biochem
, vol.326
, pp. 100-105
-
-
Hendricks, C.L.1
Ross, J.R.2
Pichersky, E.3
Noel, J.P.4
Zhou, Z.S.5
-
25
-
-
33644672263
-
An enzymecoupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases
-
PMID:16460659
-
Dorgan KM, Wooderchak WL, Wynn DP, Karschner EL, Alfaro JF, Cui Y, et al. An enzymecoupled continuous spectrophotometric assay for S-adenosylmethionine- dependent methyltransferases. Anal Biochem 2006; 350:249-55; PMID:16460659; http://dx.doi.org/10.1016/j.ab.2006.01.004.
-
(2006)
Anal Biochem
, vol.350
, pp. 249-255
-
-
Dorgan, K.M.1
Wooderchak, W.L.2
Wynn, D.P.3
Karschner, E.L.4
Alfaro, J.F.5
Cui, Y.6
-
26
-
-
77952884316
-
An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases
-
PMID:20227379
-
Ibáñez G, McBean JL, Astudillo YM, Luo MK. An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases. Anal Biochem 2010; 401:203-10; PMID:20227379; http://dx.doi.org/10.1016/j.ab.2010.03.010.
-
(2010)
Anal Biochem
, vol.401
, pp. 203-210
-
-
Ibáñez, G.1
McBean, J.L.2
Astudillo, Y.M.3
Luo, M.K.4
-
27
-
-
77952113727
-
A continuous, quantitative fluorescent assay for plant caffeic acid O-methyltransferases
-
PMID:20397733
-
Palmer NA, Sattler SE, Saathoff AJ, Sarath G. A continuous, quantitative fluorescent assay for plant caffeic acid O-methyltransferases. J Agric Food Chem 2010; 58:5220-6; PMID:20397733; http://dx.doi.org/10.1021/jf904445q.
-
(2010)
J Agric Food Chem
, vol.58
, pp. 5220-5226
-
-
Palmer, N.A.1
Sattler, S.E.2
Saathoff, A.J.3
Sarath, G.4
-
28
-
-
0030597298
-
Characterization of recombinant Eschericha coli 5′- methylthioadenosine/S-adenosylhomocysteine nucleosidase: Analysis of enzymatic activity and substrate specificity
-
PMID:8941345
-
Cornell KA, Swarts WE, Barry RD, Riscoe MK. Characterization of recombinant Eschericha coli 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase: analysis of enzymatic activity and substrate specificity. Biochem Biophys Res Commun 1996; 228:724-32; PMID:8941345; http://dx.doi.org/10.1006/ bbrc.1996.1723.
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 724-732
-
-
Cornell, K.A.1
Swarts, W.E.2
Barry, R.D.3
Riscoe, M.K.4
-
29
-
-
79953188722
-
Small molecule inhibitors that selectively block dengue virus methyltransferase
-
PMID:21147775
-
Lim SP, Sonntag LS, Noble C, Nilar SH, Ng RH, Zou G, et al. Small molecule inhibitors that selectively block dengue virus methyltransferase. J Biol Chem 2011; 286:6233-40; PMID:21147775; http://dx.doi.org/10.1074/jbc.M110. 179184.
-
(2011)
J Biol Chem
, vol.286
, pp. 6233-6240
-
-
Lim, S.P.1
Sonntag, L.S.2
Noble, C.3
Nilar, S.H.4
Ng, R.H.5
Zou, G.6
-
30
-
-
77957039757
-
Trimethylguanosine capping selectively promotes expression of Revdependent HIV-1 RNAs
-
PMID:20679221
-
Yedavalli VSRK, Jeang KT. Trimethylguanosine capping selectively promotes expression of Revdependent HIV-1 RNAs. Proc Natl Acad Sci USA 2010; 107:14787-92; PMID:20679221; http://dx.doi. org/10.1073/pnas.1009490107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14787-14792
-
-
Yedavalli, V.1
Jeang, K.T.2
-
31
-
-
0345275879
-
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
-
PMID:14633667
-
Fang MZ, Wang YM, Ai N, Hou Z, Sun Y, Lu H, et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003; 63:7563-70; PMID:14633667.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.M.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
-
32
-
-
31544441371
-
Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
-
PMID:16081510
-
Lee WJ, Zhu BT. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 2006; 27:269-77; PMID:16081510; http://dx.doi.org/10.1093/carcin/ bgi206.
-
(2006)
Carcinogenesis
, vol.27
, pp. 269-277
-
-
Lee, W.J.1
Zhu, B.T.2
-
33
-
-
57649120781
-
Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: Functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors and RNA decay pathways
-
PMID:18775984
-
Hausmann S, Zheng S, Costanzo M, Brost RL, Garcin D, Boone C, et al. Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors and RNA decay pathways. J Biol Chem 2008; 283:31706-18; PMID:18775984; http://dx.doi.org/10.1074/jbc. M806127200.
-
(2008)
J Biol Chem
, vol.283
, pp. 31706-31718
-
-
Hausmann, S.1
Zheng, S.2
Costanzo, M.3
Brost, R.L.4
Garcin, D.5
Boone, C.6
-
34
-
-
77951154264
-
Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: Proteins implicated in pre-mRNA splicing
-
PMID:20360394
-
Chang J, Schwer B, Shuman S. Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: proteins implicated in pre-mRNA splicing. RNA 2010; 16:1018-31; PMID:20360394; http://dx.doi.org/10.1261/rna.2082610.
-
(2010)
RNA
, vol.16
, pp. 1018-1031
-
-
Chang, J.1
Schwer, B.2
Shuman, S.3
-
35
-
-
15444370839
-
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family
-
PMID:15637073
-
Watanabe K, Nureki O, Fukai S, Ishii R, Okamoto H, Yokoyama S, et al. Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family. J Biol Chem 2005; 280:10368-77; PMID:15637073; http://dx.doi.org/10.1074/jbc.M411209200.
-
(2005)
J Biol Chem
, vol.280
, pp. 10368-10377
-
-
Watanabe, K.1
Nureki, O.2
Fukai, S.3
Ishii, R.4
Okamoto, H.5
Yokoyama, S.6
-
36
-
-
0032499664
-
Recognition of capped RNA substrates by VP39, the vaccinia virus-encoded mRNA cap-specific 2′-O-methyltransferase
-
PMID:9622508
-
Lockless SW, Cheng HT, Hodel AE, Quiocho FA, Gershon PD. Recognition of capped RNA substrates by VP39, the vaccinia virus-encoded mRNA cap-specific 2′-O-methyltransferase. Biochemistry 1998; 37:8564-74; PMID:9622508; http://dx.doi.org/10.1021/bi980178m.
-
(1998)
Biochemistry
, vol.37
, pp. 8564-8574
-
-
Lockless, S.W.1
Cheng, H.T.2
Hodel, A.E.3
Quiocho, F.A.4
Gershon, P.D.5
-
37
-
-
79953139279
-
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling
-
PMID:21037259
-
Motorin Y, Burhenne J, Teimer R, Koynov K, Willnow S, Weinhold E, et al. Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res 2011; 39:1943-52; PMID:21037259; http://dx.doi.org/10.1093/nar/gkq825.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1943-1952
-
-
Motorin, Y.1
Burhenne, J.2
Teimer, R.3
Koynov, K.4
Willnow, S.5
Weinhold, E.6
-
38
-
-
77954851029
-
Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling
-
PMID:20572224
-
Peters W, Willnow S, Duisken M, Kleine H, Macherey T, Duncan KE, et al. Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling. Angew Chem Int Ed Engl 2010; 49:5170-3; PMID:20572224; http://dx.doi.org/10.1002/anie.201001240.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 5170-5173
-
-
Peters, W.1
Willnow, S.2
Duisken, M.3
Kleine, H.4
Macherey, T.5
Duncan, K.E.6
-
39
-
-
79960496067
-
Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling
-
PMID:21495674
-
Islam K, Zheng W, Yu H, Deng H, Luo M. Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. ACS Chem Biol 2011; 6:679-84; PMID:21495674; http://dx.doi.org/10.1021/cb2000567.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 679-684
-
-
Islam, K.1
Zheng, W.2
Yu, H.3
Deng, H.4
Luo, M.5
-
41
-
-
0035180468
-
Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli 5′-methylthioadenosine/Sadenosylhomocysteine nucleosidase
-
PMID:11134941
-
Lee JE, Cornell KA, Riscoe MK, Howell PL. Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli 5′-methylthioadenosine/Sadenosylhomocysteine nucleosidase. Acta Crystallogr D Biol Crystallogr 2001; 57:150-2; PMID:11134941; http://dx.doi.org/10.1107/S0907444900014669.
-
(2001)
Acta Crystallogr D Biol Crystallogr
, vol.57
, pp. 150-152
-
-
Lee, J.E.1
Cornell, K.A.2
Riscoe, M.K.3
Howell, P.L.4
-
42
-
-
0035949513
-
Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site
-
PMID:11553770
-
Hilgers MT, Ludwig ML. Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site. Proc Natl Acad Sci USA 2001; 98:11169-74; PMID:11553770; http://dx.doi.org/10.1073/pnas.191223098.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11169-11174
-
-
Hilgers, M.T.1
Ludwig, M.L.2
|