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Volumn 10, Issue 3, 2015, Pages 468-476

Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation

Author keywords

Alpha7 nAChR; Cholinergic anti inflammatory pathway; Inflammation; Monocyte derived macrophages (MDMs); Nicotinic acetylcholine receptor

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BUNGAROTOXIN RECEPTOR; CHOLINE ACETYLTRANSFERASE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NICOTINIC RECEPTOR; NORADRENALIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; JAK2 PROTEIN, HUMAN; JANUS KINASE 2; STAT3 PROTEIN, HUMAN;

EID: 84939522882     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-015-9601-5     Document Type: Article
Times cited : (165)

References (51)
  • 1
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons
    • COI: 1:STN:280:DyaK1c7ns1Kmtw%3D%3D, PID: 9517478
    • Alkondon M, Pereira EF, Cortes WS et al (1997) Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. Eur J Neurosci 9:2734–2742
    • (1997) Eur J Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.2    Cortes, W.S.3
  • 2
    • 0032555779 scopus 로고    scopus 로고
    • Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor
    • COI: 1:CAS:528:DyaK1cXlsFertbc%3D, PID: 9748559
    • Arias HR (1998) Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor. Biochim Biophys Acta 1376:173–220
    • (1998) Biochim Biophys Acta , vol.1376 , pp. 173-220
    • Arias, H.R.1
  • 3
    • 78650997226 scopus 로고    scopus 로고
    • Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS
    • COI: 1:CAS:528:DC%2BC3MXntVahuw%3D%3D, PID: 20926142
    • Benfante R, Antonini RA, De Pizzol M et al (2011) Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS. J Neuroimmunol 230:74–84. doi:10.1016/j.jneuroim.2010.09.008
    • (2011) J Neuroimmunol , vol.230 , pp. 74-84
    • Benfante, R.1    Antonini, R.A.2    De Pizzol, M.3
  • 4
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • COI: 1:CAS:528:DC%2BD3cXjslyltbY%3D, PID: 10839541
    • Borovikova LV, Ivanova S, Zhang M et al (2000) Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405:458–462. doi:10.1038/35013070
    • (2000) Nature , vol.405 , pp. 458-462
    • Borovikova, L.V.1    Ivanova, S.2    Zhang, M.3
  • 5
    • 84861540638 scopus 로고    scopus 로고
    • MG624, an α7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway
    • COI: 1:CAS:528:DC%2BC38XitFGgsbY%3D, PID: 22198237
    • Brown KC, Lau JK, Dom AM et al (2012) MG624, an α7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway. Angiogenesis 15:99–114. doi:10.1007/s10456-011-9246-9
    • (2012) Angiogenesis , vol.15 , pp. 99-114
    • Brown, K.C.1    Lau, J.K.2    Dom, A.M.3
  • 6
    • 0034177065 scopus 로고    scopus 로고
    • The torpedo electrocyte: a model system to study membrane-cytoskeleton interactions at the postsynaptic membrane
    • COI: 1:CAS:528:DC%2BD3cXivVCnurs%3D, PID: 10757880
    • Cartaud J, Cartaud A, Kordeli E et al (2000) The torpedo electrocyte: a model system to study membrane-cytoskeleton interactions at the postsynaptic membrane. Microsc Res Tech 49:73–83. doi:10.1002/(SICI)1097-0029(20000401)49:1<73::AID-JEMT8>3.0.CO;2-L
    • (2000) Microsc Res Tech , vol.49 , pp. 73-83
    • Cartaud, J.1    Cartaud, A.2    Kordeli, E.3
  • 7
    • 0032215090 scopus 로고    scopus 로고
    • Allosteric receptors after 30 years
    • COI: 1:CAS:528:DyaK1cXotVSrt7Y%3D, PID: 9856454
    • Changeux JP, Edelstein SJ (1998) Allosteric receptors after 30 years. Neuron 21:959–980
    • (1998) Neuron , vol.21 , pp. 959-980
    • Changeux, J.P.1    Edelstein, S.J.2
  • 9
    • 27344437870 scopus 로고    scopus 로고
    • Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases
    • COI: 1:CAS:528:DC%2BD2MXht1Shsb7K, PID: 16251431
    • Charpantier E, Wiesner A, Huh K-H et al (2005) Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases. J Neurosci 25:9836–9849. doi:10.1523/JNEUROSCI. 3497-05.2005
    • (2005) J Neurosci , vol.25 , pp. 9836-9849
    • Charpantier, E.1    Wiesner, A.2    Huh, K.-H.3
  • 10
    • 0025478843 scopus 로고
    • Ligand-gated ion channels. Homology and diversity
    • COI: 1:CAS:528:DyaK38XisVynurw%3D, PID: 1725701
    • Cockcroft VB, Osguthorpe DJ, Barnard EA et al (1990) Ligand-gated ion channels. Homology and diversity. Mol Neurobiol 4:129–169. doi:10.1007/BF02780338
    • (1990) Mol Neurobiol , vol.4 , pp. 129-169
    • Cockcroft, V.B.1    Osguthorpe, D.J.2    Barnard, E.A.3
  • 11
    • 0025828670 scopus 로고
    • Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor
    • COI: 1:CAS:528:DyaK3MXisVejsbY%3D, PID: 2005979
    • Cooper E, Couturier S, Ballivet M (1991) Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor. Nature 350:235–238. doi:10.1038/350235a0
    • (1991) Nature , vol.350 , pp. 235-238
    • Cooper, E.1    Couturier, S.2    Ballivet, M.3
  • 12
    • 17544372511 scopus 로고    scopus 로고
    • Nicotinic receptors at the amino acid level
    • COI: 1:CAS:528:DC%2BD3cXjs1yhtrs%3D, PID: 10836143
    • Corringer PJ, Le Novère N, Changeux JP (2000) Nicotinic receptors at the amino acid level. Annu Rev Pharmacol Toxicol 40:431–458. doi:10.1146/annurev.pharmtox.40.1.431
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 431-458
    • Corringer, P.J.1    Le Novère, N.2    Changeux, J.P.3
  • 13
    • 80053244433 scopus 로고    scopus 로고
    • Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation
    • COI: 1:CAS:528:DC%2BC3MXht1ylu7vJ, PID: 21957249
    • daCosta CJB, Free CR, Corradi J et al (2011) Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation. J Neurosci 31:13870–13879. doi:10.1523/JNEUROSCI. 2652-11.2011
    • (2011) J Neurosci , vol.31 , pp. 13870-13879
    • daCosta, C.J.B.1    Free, C.R.2    Corradi, J.3
  • 14
    • 23844454674 scopus 로고    scopus 로고
    • Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
    • PID: 16025117
    • De Jonge WJ, van der Zanden EP, The FO et al (2005) Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol 6:844–851. doi:10.1038/ni1229
    • (2005) Nat Immunol , vol.6 , pp. 844-851
    • De Jonge, W.J.1    van der Zanden, E.P.2    The, F.O.3
  • 15
    • 78650939541 scopus 로고    scopus 로고
    • Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response
    • PID: 21047781
    • De Lucas-Cerrillo AM, Maldifassi MC, Arnalich F et al (2011) Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response. J Biol Chem 286:594–606. doi:10.1074/jbc.M110.180067
    • (2011) J Biol Chem , vol.286 , pp. 594-606
    • De Lucas-Cerrillo, A.M.1    Maldifassi, M.C.2    Arnalich, F.3
  • 16
    • 44549087726 scopus 로고    scopus 로고
    • Chronic exposure of human macrophages in vitro to morphine and methadone induces a putative tolerant/dependent state
    • PID: 18396338
    • Delgado-Vélez M, Lugo-Chinchilla A, Lizardo L et al (2008) Chronic exposure of human macrophages in vitro to morphine and methadone induces a putative tolerant/dependent state. J Neuroimmunol 196:94–100. doi:10.1016/j.jneuroim.2008.03.004
    • (2008) J Neuroimmunol , vol.196 , pp. 94-100
    • Delgado-Vélez, M.1    Lugo-Chinchilla, A.2    Lizardo, L.3
  • 17
    • 0027522236 scopus 로고
    • Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels
    • PID: 7508983
    • Devillers-Thiéry A, Galzi JL, Eiselé JL et al (1993) Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. J Membr Biol 136:97–112
    • (1993) J Membr Biol , vol.136 , pp. 97-112
    • Devillers-Thiéry, A.1    Galzi, J.L.2    Eiselé, J.L.3
  • 18
    • 0024432575 scopus 로고
    • The sidedness of the COOH terminus of the acetylcholine receptor delta subunit
    • COI: 1:CAS:528:DyaL1MXlsV2it7Y%3D, PID: 2768272
    • DiPaola M, Czajkowski C, Karlin A (1989) The sidedness of the COOH terminus of the acetylcholine receptor delta subunit. J Biol Chem 264:15457–15463
    • (1989) J Biol Chem , vol.264 , pp. 15457-15463
    • DiPaola, M.1    Czajkowski, C.2    Karlin, A.3
  • 19
    • 0025884565 scopus 로고
    • Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain
    • COI: 1:CAS:528:DyaK3MXlsFSms7w%3D, PID: 2064379
    • Galzi JL, Revah F, Bessis A, Changeux JP (1991) Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annu Rev Pharmacol Toxicol 31:37–72. doi:10.1146/annurev.pa.31.040191.000345
    • (1991) Annu Rev Pharmacol Toxicol , vol.31 , pp. 37-72
    • Galzi, J.L.1    Revah, F.2    Bessis, A.3    Changeux, J.P.4
  • 20
    • 58549118920 scopus 로고    scopus 로고
    • Local and global calcium signals associated with the opening of neuronal alpha7 nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BD1MXhtFCjs7c%3D, PID: 19038445
    • Gilbert D, Lecchi M, Arnaudeau S et al (2009) Local and global calcium signals associated with the opening of neuronal alpha7 nicotinic acetylcholine receptors. Cell Calcium 45:198–207. doi:10.1016/j.ceca.2008.10.003
    • (2009) Cell Calcium , vol.45 , pp. 198-207
    • Gilbert, D.1    Lecchi, M.2    Arnaudeau, S.3
  • 21
    • 20944441082 scopus 로고    scopus 로고
    • A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization
    • COI: 1:CAS:528:DC%2BD2MXktFKgtLo%3D, PID: 15858066
    • Hurst RS, Hajós M, Raggenbass M et al (2005) A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J Neurosci 25:4396–4405. doi:10.1523/JNEUROSCI. 5269-04.2005
    • (2005) J Neurosci , vol.25 , pp. 4396-4405
    • Hurst, R.S.1    Hajós, M.2    Raggenbass, M.3
  • 22
    • 0035979711 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors: from protein structure to function
    • COI: 1:CAS:528:DC%2BD3MXmsFelt7w%3D, PID: 11532443
    • Itier V, Bertrand D (2001) Neuronal nicotinic receptors: from protein structure to function. FEBS Lett 504:118–125
    • (2001) FEBS Lett , vol.504 , pp. 118-125
    • Itier, V.1    Bertrand, D.2
  • 23
    • 79960123457 scopus 로고    scopus 로고
    • Tristetraprolin mediates anti-inflammatory effects of nicotine in lipopolysaccharide-stimulated macrophages
    • COI: 1:CAS:528:DC%2BC3MXosFGmsL4%3D, PID: 21606497
    • Joe Y, Kim HJ, Kim S et al (2011) Tristetraprolin mediates anti-inflammatory effects of nicotine in lipopolysaccharide-stimulated macrophages. J Biol Chem 286:24735–24742. doi:10.1074/jbc.M110.204859
    • (2011) J Biol Chem , vol.286 , pp. 24735-24742
    • Joe, Y.1    Kim, H.J.2    Kim, S.3
  • 24
    • 34447639624 scopus 로고    scopus 로고
    • Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity
    • COI: 1:CAS:528:DC%2BD2sXptFCntbo%3D, PID: 17651090
    • Kalamida D, Poulas K, Avramopoulou V et al (2007) Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity. FEBS J 274:3799–3845. doi:10.1111/j.1742-4658.2007.05935.x
    • (2007) FEBS J , vol.274 , pp. 3799-3845
    • Kalamida, D.1    Poulas, K.2    Avramopoulou, V.3
  • 25
    • 0036480194 scopus 로고    scopus 로고
    • Emerging structure of the nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BD38Xhslyju7Y%3D, PID: 11836518
    • Karlin A (2002) Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci 3:102–114. doi:10.1038/nrn731
    • (2002) Nat Rev Neurosci , vol.3 , pp. 102-114
    • Karlin, A.1
  • 26
    • 0029593370 scopus 로고
    • Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
    • COI: 1:CAS:528:DyaK28Xht1Smsw%3D%3D, PID: 8845149
    • Karlin A, Akabas MH (1995) Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15:1231–1244
    • (1995) Neuron , vol.15 , pp. 1231-1244
    • Karlin, A.1    Akabas, M.H.2
  • 27
    • 84899575657 scopus 로고    scopus 로고
    • Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation
    • COI: 1:CAS:528:DC%2BC2cXnt1Cmtrg%3D, PID: 24298024
    • Kim T-H, Kim S-J, Lee S-M (2014) Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation. J Infect Dis 209:1668–1677. doi:10.1093/infdis/jit669
    • (2014) J Infect Dis , vol.209 , pp. 1668-1677
    • Kim, T.-H.1    Kim, S.-J.2    Lee, S.-M.3
  • 28
    • 0033032332 scopus 로고    scopus 로고
    • Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation
    • PID: 10233052
    • Le Novère N, Corringer PJ, Changeux JP (1999) Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation. Biophys J 76:2329–2345. doi:10.1016/S0006-3495(99)77390-X
    • (1999) Biophys J , vol.76 , pp. 2329-2345
    • Le Novère, N.1    Corringer, P.J.2    Changeux, J.P.3
  • 29
    • 0036891522 scopus 로고    scopus 로고
    • The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences
    • PID: 12436412
    • Le Novère N, Corringer P-J, Changeux J-P (2002) The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol 53:447–456. doi:10.1002/neu.10153
    • (2002) J Neurobiol , vol.53 , pp. 447-456
    • Le Novère, N.1    Corringer, P.-J.2    Changeux, J.-P.3
  • 30
    • 38049088141 scopus 로고    scopus 로고
    • Evaluation of a chemiluminescent assay for analysis of choline in human plasma and whole blood
    • Lueders C, Danne O, Müller C et al (2007) Evaluation of a chemiluminescent assay for analysis of choline in human plasma and whole blood. Lab Med 38:726–728. doi:10.1309/1N2NAYWQ53QVR6FX
    • (2007) Lab Med , vol.38 , pp. 726-728
    • Lueders, C.1    Danne, O.2    Müller, C.3
  • 31
    • 84907916535 scopus 로고    scopus 로고
    • A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages
    • PID: 25259522
    • Maldifassi MC, Atienza G, Arnalich F et al (2014) A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages. PLoS ONE 9:e108397. doi:10.1371/journal.pone.0108397
    • (2014) PLoS ONE , vol.9 , pp. e108397
    • Maldifassi, M.C.1    Atienza, G.2    Arnalich, F.3
  • 32
    • 0024319944 scopus 로고
    • Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators
    • COI: 1:CAS:528:DyaL1MXkvFSmsrg%3D, PID: 2663167
    • Ochoa EL, Chattopadhyay A, McNamee MG (1989) Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators. Cell Mol Neurobiol 9:141–178
    • (1989) Cell Mol Neurobiol , vol.9 , pp. 141-178
    • Ochoa, E.L.1    Chattopadhyay, A.2    McNamee, M.G.3
  • 33
    • 84897986694 scopus 로고    scopus 로고
    • Merging old and new perspectives on nicotinic acetylcholine receptors
    • COI: 1:CAS:528:DC%2BC2cXivF2msLo%3D, PID: 24486571
    • Papke RL (2014) Merging old and new perspectives on nicotinic acetylcholine receptors. Biochem Pharmacol 89:1–11. doi:10.1016/j.bcp.2014.01.029
    • (2014) Biochem Pharmacol , vol.89 , pp. 1-11
    • Papke, R.L.1
  • 34
    • 55049094829 scopus 로고    scopus 로고
    • Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling
    • COI: 1:CAS:528:DC%2BD1cXht1ems7%2FP, PID: 18584048
    • Parrish WR, Rosas-Ballina M, Gallowitsch-Puerta M et al (2008) Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. Mol Med 14:567–574. doi:10.2119/2008-00079.Parrish
    • (2008) Mol Med , vol.14 , pp. 567-574
    • Parrish, W.R.1    Rosas-Ballina, M.2    Gallowitsch-Puerta, M.3
  • 35
    • 0033964077 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors in the human brain
    • COI: 1:CAS:528:DC%2BD3cXisValurc%3D, PID: 10759066
    • Paterson D, Nordberg A (2000) Neuronal nicotinic receptors in the human brain. Prog Neurobiol 61:75–111
    • (2000) Prog Neurobiol , vol.61 , pp. 75-111
    • Paterson, D.1    Nordberg, A.2
  • 36
    • 65249153042 scopus 로고    scopus 로고
    • Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome
    • COI: 1:CAS:528:DC%2BD1MXivFOmsr8%3D, PID: 19714875
    • Paulo JA, Brucker WJ, Hawrot E (2009) Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome. J Proteome Res 8:1849–1858. doi:10.1021/pr800731z
    • (2009) J Proteome Res , vol.8 , pp. 1849-1858
    • Paulo, J.A.1    Brucker, W.J.2    Hawrot, E.3
  • 37
    • 77956492231 scopus 로고    scopus 로고
    • Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis
    • PID: 20706987
    • Peña G, Cai B, Liu J et al (2010) Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis. Eur J Immunol 40:2580–2589. doi:10.1002/eji.201040540
    • (2010) Eur J Immunol , vol.40 , pp. 2580-2589
    • Peña, G.1    Cai, B.2    Liu, J.3
  • 38
    • 80053593864 scopus 로고    scopus 로고
    • Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit
    • COI: 1:CAS:528:DC%2BC3MXht1Gms7%2FE, PID: 21921156
    • Rosas-Ballina M, Olofsson PS, Ochani M et al (2011) Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science 334:98–101. doi:10.1126/science.1209985
    • (2011) Science , vol.334 , pp. 98-101
    • Rosas-Ballina, M.1    Olofsson, P.S.2    Ochani, M.3
  • 39
    • 84860444144 scopus 로고    scopus 로고
    • α7-Nicotinic acetylcholine receptors: an old actor for new different roles
    • COI: 1:CAS:528:DC%2BC38Xht1CgsrvM, PID: 22300022
    • Russo P, Taly A (2012) α7-Nicotinic acetylcholine receptors: an old actor for new different roles. Curr Drug Targets 13:574–578
    • (2012) Curr Drug Targets , vol.13 , pp. 574-578
    • Russo, P.1    Taly, A.2
  • 40
    • 84893098491 scopus 로고    scopus 로고
    • Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers
    • COI: 1:CAS:528:DC%2BC2cXptVyqtw%3D%3D, PID: 24398389
    • Schaal C, Chellappan SP (2014) Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers. Mol Cancer Res 12:14–23. doi:10.1158/1541-7786.MCR-13-0541
    • (2014) Mol Cancer Res , vol.12 , pp. 14-23
    • Schaal, C.1    Chellappan, S.P.2
  • 41
    • 67549109441 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system
    • COI: 1:CAS:528:DC%2BD1MXmvVSltL8%3D, PID: 19448647
    • Shen J, Yakel JL (2009) Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system. Acta Pharmacol Sin 30:673–680. doi:10.1038/aps.2009.64
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 673-680
    • Shen, J.1    Yakel, J.L.2
  • 42
    • 68849123147 scopus 로고    scopus 로고
    • Editorial: To channel or not to channel? Functioning of nicotinic acetylcholine receptors in leukocytes
    • COI: 1:CAS:528:DC%2BD1MXotlCkt70%3D, PID: 19567410
    • Skok MV (2009) Editorial: To channel or not to channel? Functioning of nicotinic acetylcholine receptors in leukocytes. J Leukoc Biol 86:1–3. doi:10.1189/JLB.0209106
    • (2009) J Leukoc Biol , vol.86 , pp. 1-3
    • Skok, M.V.1
  • 43
    • 84922481769 scopus 로고    scopus 로고
    • Neural control of the immune system
    • PID: 25039084
    • Sundman E, Olofsson PS (2014) Neural control of the immune system. Adv Physiol Educ 38:135–139
    • (2014) Adv Physiol Educ , vol.38 , pp. 135-139
    • Sundman, E.1    Olofsson, P.S.2
  • 44
    • 79956077128 scopus 로고    scopus 로고
    • Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine attenuates inflammatory response in macrophages and improves survival in experimental model of sepsis through heme oxygenase-1 induction
    • COI: 1:CAS:528:DC%2BC3MXlvFOisbw%3D, PID: 21083424
    • Tsoyi K, Jang HJ, Kim JW et al (2011) Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine attenuates inflammatory response in macrophages and improves survival in experimental model of sepsis through heme oxygenase-1 induction. Antioxid Redox Signal 14:2057–2070. doi:10.1089/ars.2010.3555
    • (2011) Antioxid Redox Signal , vol.14 , pp. 2057-2070
    • Tsoyi, K.1    Jang, H.J.2    Kim, J.W.3
  • 45
    • 0035999547 scopus 로고    scopus 로고
    • Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes
    • COI: 1:CAS:528:DC%2BD38XjvVaqt7w%3D, PID: 12020960
    • Villiger Y, Szanto I, Jaconi S et al (2002) Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes. J Neuroimmunol 126:86–98
    • (2002) J Neuroimmunol , vol.126 , pp. 86-98
    • Villiger, Y.1    Szanto, I.2    Jaconi, S.3
  • 46
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
    • COI: 1:CAS:528:DC%2BD3sXlsVantA%3D%3D, PID: 12508119
    • Wang H, Yu M, Ochani M et al (2003) Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421:384–388. doi:10.1038/nature01339
    • (2003) Nature , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3
  • 47
    • 9144263639 scopus 로고    scopus 로고
    • Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
    • COI: 1:CAS:528:DC%2BD2cXptVOgtr8%3D, PID: 15502843
    • Wang H, Liao H, Ochani M et al (2004) Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med 10:1216–1221. doi:10.1038/nm1124
    • (2004) Nat Med , vol.10 , pp. 1216-1221
    • Wang, H.1    Liao, H.2    Ochani, M.3
  • 48
    • 84907190328 scopus 로고    scopus 로고
    • The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7
    • COI: 1:CAS:528:DC%2BC2cXhsFOqtrbI, PID: 25056953
    • Wang Y, Xiao C, Indersmitten T et al (2014) The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7. J Biol Chem 289:26451–26463. doi:10.1074/jbc.M114.582858
    • (2014) J Biol Chem , vol.289 , pp. 26451-26463
    • Wang, Y.1    Xiao, C.2    Indersmitten, T.3
  • 49
    • 34249868449 scopus 로고    scopus 로고
    • Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB
    • COI: 1:CAS:528:DC%2BD2sXmsFSgsbY%3D, PID: 17510282
    • Yang J, Liao X, Agarwal MK et al (2007) Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes Dev 21:1396–1408. doi:10.1101/gad.1553707
    • (2007) Genes Dev , vol.21 , pp. 1396-1408
    • Yang, J.1    Liao, X.2    Agarwal, M.K.3
  • 50
    • 33748713337 scopus 로고    scopus 로고
    • Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7
    • COI: 1:CAS:528:DC%2BD28XhtF2qsbnO, PID: 16968406
    • Yoshikawa H, Kurokawa M, Ozaki N et al (2006) Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7. Clin Exp Immunol 146:116–123. doi:10.1111/j.1365-2249.2006.03169.x
    • (2006) Clin Exp Immunol , vol.146 , pp. 116-123
    • Yoshikawa, H.1    Kurokawa, M.2    Ozaki, N.3
  • 51
    • 0028178802 scopus 로고
    • Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels
    • COI: 1:CAS:528:DyaK2cXitlKqs7s%3D, PID: 7507338
    • Zhang ZW, Vijayaraghavan S, Berg DK (1994) Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron 12:167–177
    • (1994) Neuron , vol.12 , pp. 167-177
    • Zhang, Z.W.1    Vijayaraghavan, S.2    Berg, D.K.3


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