Chronic exposure of human macrophages in vitro to morphine and methadone induces a putative tolerant/dependent state

Journal of Neuroimmunology

Volumn 196, Issue 1-2, 2008, Pages 94-100

  Delgado Vélez, Manuel ^a   Lugo Chinchilla, Ana ^b   Lizardo, Luis ^a   Morales, Irmarie ^a   Robles, Yarelis ^b   Bruno, Nimaris ^a   Rodríguez, José W ^c   Ríos Olivares, Eddy ^c   Correa, Miguel ^d   Renaud, Fernando L ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b Interamerican University   (Puerto Rico)

^c Universidad Central del Caribe School of Medicine   (Puerto Rico)

^d Mental Hlth Ann Addict Serv A   (Puerto Rico)

Author keywords

Dependence; Methadone; Morphine; Phagocytosis; Tolerance

Indexed keywords

METHADONE; MORPHINE;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; MACROPHAGE; MALE; MONOCYTE; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; FEMALE; HUMANS; MACROPHAGES; MALE; METHADONE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS;

EID: 44549087726     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.03.004     Document Type: Article

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