메뉴 건너뛰기




Volumn 71, Issue , 2017, Pages 165-173

Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs

Author keywords

Animal models; Audiogenic seizures; Epilepsy; Epileptogenesis; Generalized seizure; Neurotransmitters

Indexed keywords

ADENOSINE; ANTICONVULSIVE AGENT; ARIPIPRAZOLE; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; CONVULSANT AGENT; DIAZEPAM; ETHOSUXIMIDE; EXCITATORY AMINO ACID; FELBAMATE; GABAPENTIN; HALOPERIDOL; LAMOTRIGINE; LEVETIRACETAM; NIMODIPINE; OXCARBAZEPINE; PERAMPANEL; PHENOBARBITAL; PHENYTOIN; QUETIAPINE; RETIGABINE; RISPERIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID;

EID: 84939508263     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2015.06.030     Document Type: Review
Times cited : (39)

References (163)
  • 1
    • 0029046087 scopus 로고
    • Neurotransmission in epilepsy
    • Meldrum, B.S., Neurotransmission in epilepsy. Epilepsia 36:Suppl. 1 (1995), S30–S35.
    • (1995) Epilepsia , vol.36 , pp. S30-S35
    • Meldrum, B.S.1
  • 3
    • 0030070426 scopus 로고    scopus 로고
    • Targeting epilepsy genes
    • Noebels, J.L., Targeting epilepsy genes. Neuron 16 (1996), 241–244.
    • (1996) Neuron , vol.16 , pp. 241-244
    • Noebels, J.L.1
  • 4
    • 0034799972 scopus 로고    scopus 로고
    • Genetics of the epilepsies
    • Berkovic, S.F., Scheffer, I.E., Genetics of the epilepsies. Epilepsia 42:Suppl. 5 (2001), 16–23.
    • (2001) Epilepsia , vol.42 , pp. 16-23
    • Berkovic, S.F.1    Scheffer, I.E.2
  • 5
    • 0009673010 scopus 로고    scopus 로고
    • Ion channel genes and human neurological disease: recent progress, prospects, and challenges
    • Cooper, E.C., Jan, L.Y., Ion channel genes and human neurological disease: recent progress, prospects, and challenges. Proc Natl Acad Sci U S A 96 (1999), 4759–4766.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4759-4766
    • Cooper, E.C.1    Jan, L.Y.2
  • 6
    • 79955677603 scopus 로고    scopus 로고
    • Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs
    • Loscher, W., Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs. Seizure 20 (2011), 359–368.
    • (2011) Seizure , vol.20 , pp. 359-368
    • Loscher, W.1
  • 7
    • 0001699915 scopus 로고    scopus 로고
    • Overview of the current animal models for human seizure and epileptic disorders
    • Sarkisian, M.R., Overview of the current animal models for human seizure and epileptic disorders. Epilepsy Behav 2 (2001), 201–216.
    • (2001) Epilepsy Behav , vol.2 , pp. 201-216
    • Sarkisian, M.R.1
  • 8
    • 0032619731 scopus 로고    scopus 로고
    • Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures
    • Seyfried, T.N., Todorova, M.T., Poderycki, M.J., Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures. Adv Neurol 79 (1999), 279–290.
    • (1999) Adv Neurol , vol.79 , pp. 279-290
    • Seyfried, T.N.1    Todorova, M.T.2    Poderycki, M.J.3
  • 9
    • 0031982542 scopus 로고    scopus 로고
    • The photosensitive epilepsy of the baboon. A model of generalized reflex epilepsy
    • Menini, C., Silva-Barrat, C., The photosensitive epilepsy of the baboon. A model of generalized reflex epilepsy. Adv Neurol 75 (1998), 29–47.
    • (1998) Adv Neurol , vol.75 , pp. 29-47
    • Menini, C.1    Silva-Barrat, C.2
  • 10
    • 2942703793 scopus 로고    scopus 로고
    • An avian model of genetic reflex epilepsy
    • Batini, C., Teillet, M.A., Naquet, R., An avian model of genetic reflex epilepsy. Arch Ital Biol 142 (2004), 297–312.
    • (2004) Arch Ital Biol , vol.142 , pp. 297-312
    • Batini, C.1    Teillet, M.A.2    Naquet, R.3
  • 11
    • 0029914763 scopus 로고    scopus 로고
    • Hyperthermic seizures: an animal model for hot-water epilepsy
    • Ullal, G.R., Satishchandra, P., Shankar, S.K., Hyperthermic seizures: an animal model for hot-water epilepsy. Seizure 5 (1996), 221–228.
    • (1996) Seizure , vol.5 , pp. 221-228
    • Ullal, G.R.1    Satishchandra, P.2    Shankar, S.K.3
  • 12
    • 0025350288 scopus 로고
    • Mapping of two genes that influence susceptibility to audiogenic seizures in crosses of C57BL/6J and DBA/2J mice
    • Neumann, P.E., Seyfried, T.N., Mapping of two genes that influence susceptibility to audiogenic seizures in crosses of C57BL/6J and DBA/2J mice. Behav Genet 20 (1990), 307–323.
    • (1990) Behav Genet , vol.20 , pp. 307-323
    • Neumann, P.E.1    Seyfried, T.N.2
  • 13
    • 0023938667 scopus 로고
    • The genetically epilepsy-prone rat
    • Faingold, C.L., The genetically epilepsy-prone rat. Gen Pharmacol 19 (1988), 331–338.
    • (1988) Gen Pharmacol , vol.19 , pp. 331-338
    • Faingold, C.L.1
  • 14
    • 0025835316 scopus 로고
    • Neurobiology of seizure predisposition in the genetically epilepsy prone rat
    • Jobe, P.C., Dailey, J.W., Neurobiology of seizure predisposition in the genetically epilepsy prone rat. Proc West Pharmacol Soc 34 (1991), 223–225.
    • (1991) Proc West Pharmacol Soc , vol.34 , pp. 223-225
    • Jobe, P.C.1    Dailey, J.W.2
  • 15
    • 0018696499 scopus 로고
    • Audiogenic seizures in mice
    • Seyfried, T.N., Audiogenic seizures in mice. Fed Proc 38 (1979), 2399–2404.
    • (1979) Fed Proc , vol.38 , pp. 2399-2404
    • Seyfried, T.N.1
  • 16
    • 0024309329 scopus 로고
    • EL mouse as a model of focal epilepsy: a review
    • King, J.T. Jr., LaMotte, C.C., EL mouse as a model of focal epilepsy: a review. Epilepsia 30 (1989), 257–265.
    • (1989) Epilepsia , vol.30 , pp. 257-265
    • King, J.T.1    LaMotte, C.C.2
  • 17
    • 0029020952 scopus 로고
    • The Mongolian gerbil in experimental epilepsy
    • Bertorelli, R., Adami, M., Ongini, E., The Mongolian gerbil in experimental epilepsy. Ital J Neurol Sci 16 (1995), 101–106.
    • (1995) Ital J Neurol Sci , vol.16 , pp. 101-106
    • Bertorelli, R.1    Adami, M.2    Ongini, E.3
  • 18
    • 0021189693 scopus 로고
    • Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures
    • Chapman, A.G., Croucher, M.J., Meldrum, B.S., Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures. Arzneimittelforschung 34 (1984), 1261–1264.
    • (1984) Arzneimittelforschung , vol.34 , pp. 1261-1264
    • Chapman, A.G.1    Croucher, M.J.2    Meldrum, B.S.3
  • 19
    • 0033870715 scopus 로고    scopus 로고
    • Developmental and genetic audiogenic seizure models: behavior and biological substrates
    • Ross, K.C., Coleman, J.R., Developmental and genetic audiogenic seizure models: behavior and biological substrates. Neurosci Biobehav Rev 24 (2000), 639–653.
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 639-653
    • Ross, K.C.1    Coleman, J.R.2
  • 20
    • 0018875341 scopus 로고
    • Genetic analysis of audiogenic seizure susceptibility in C57BL/6J X DBA/2J recombinant inbred strains of mice
    • Seyfried, T.N., Yu, R.K., Glaser, G.H., Genetic analysis of audiogenic seizure susceptibility in C57BL/6J X DBA/2J recombinant inbred strains of mice. Genetics 94 (1980), 701–718.
    • (1980) Genetics , vol.94 , pp. 701-718
    • Seyfried, T.N.1    Yu, R.K.2    Glaser, G.H.3
  • 21
    • 0017279661 scopus 로고
    • Audiogenic priming in DBA/2J and C57BL/6J mice: interactions among age, prime-to-test interval and index of seizure
    • Schreiber, R.A., Graham, J.M. Jr., Audiogenic priming in DBA/2J and C57BL/6J mice: interactions among age, prime-to-test interval and index of seizure. Dev Psychobiol 9 (1976), 57–66.
    • (1976) Dev Psychobiol , vol.9 , pp. 57-66
    • Schreiber, R.A.1    Graham, J.M.2
  • 22
    • 0019791642 scopus 로고
    • Neurotransmitter abnormalities as determinants of seizure susceptibility and intensity in the genetic models of epilepsy
    • Jobe, P.C., Laird, H.E., Neurotransmitter abnormalities as determinants of seizure susceptibility and intensity in the genetic models of epilepsy. Biochem Pharmacol 30 (1981), 3137–3144.
    • (1981) Biochem Pharmacol , vol.30 , pp. 3137-3144
    • Jobe, P.C.1    Laird, H.E.2
  • 23
    • 0017253952 scopus 로고
    • Audiogenic seizures: relation to age and mechanisms of monoamine neurotransmission
    • Kellogg, C., Audiogenic seizures: relation to age and mechanisms of monoamine neurotransmission. Brain Res 106 (1976), 87–103.
    • (1976) Brain Res , vol.106 , pp. 87-103
    • Kellogg, C.1
  • 24
    • 0037053101 scopus 로고    scopus 로고
    • Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • De Sarro, G., Di Paola, E.D., Ferreri, G., De Sarro, A., Fischer, W., Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Eur J Pharmacol 442 (2002), 205–213.
    • (2002) Eur J Pharmacol , vol.442 , pp. 205-213
    • De Sarro, G.1    Di Paola, E.D.2    Ferreri, G.3    De Sarro, A.4    Fischer, W.5
  • 25
    • 0037031608 scopus 로고    scopus 로고
    • Group III mGlu receptor agonists potentiate the anticonvulsant effect of AMPA and NMDA receptor block
    • De Sarro, G., Chimirri, A., Meldrum, B.S., Group III mGlu receptor agonists potentiate the anticonvulsant effect of AMPA and NMDA receptor block. Eur J Pharmacol 451 (2002), 55–61.
    • (2002) Eur J Pharmacol , vol.451 , pp. 55-61
    • De Sarro, G.1    Chimirri, A.2    Meldrum, B.S.3
  • 26
    • 0034646837 scopus 로고    scopus 로고
    • 7-Nitroindazole potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice
    • De Sarro, G., Gareri, P., Falconi, U., De Sarro, A., 7-Nitroindazole potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice. Eur J Pharmacol 394 (2000), 275–288.
    • (2000) Eur J Pharmacol , vol.394 , pp. 275-288
    • De Sarro, G.1    Gareri, P.2    Falconi, U.3    De Sarro, A.4
  • 27
    • 0033984914 scopus 로고    scopus 로고
    • Topiramate potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice
    • De Sarro, G., Gratteri, S., Bonacci, F., Musumeci, S.A., Elia, M., De Sarro, A., Topiramate potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice. Eur J Pharmacol 388 (2000), 163–170.
    • (2000) Eur J Pharmacol , vol.388 , pp. 163-170
    • De Sarro, G.1    Gratteri, S.2    Bonacci, F.3    Musumeci, S.A.4    Elia, M.5    De Sarro, A.6
  • 28
    • 0034129410 scopus 로고    scopus 로고
    • Influence of D-cycloserine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • De Sarro, G., Gratteri, S., Naccari, F., Pasculli, M.P., De Sarro, A., Influence of D-cycloserine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice. Epilepsy Res 40 (2000), 109–121.
    • (2000) Epilepsy Res , vol.40 , pp. 109-121
    • De Sarro, G.1    Gratteri, S.2    Naccari, F.3    Pasculli, M.P.4    De Sarro, A.5
  • 29
  • 30
    • 0026467138 scopus 로고
    • Effects of antiepileptic drugs, calcium channel blockers and other compounds on seizures induced by activation of voltage-dependent L calcium channel in DBA/2 mice
    • De Sarro, G., Ascioti, C., di Paola, E.D., Vidal, M.J., De Sarro, A., Effects of antiepileptic drugs, calcium channel blockers and other compounds on seizures induced by activation of voltage-dependent L calcium channel in DBA/2 mice. Gen Pharmacol 23 (1992), 1205–1216.
    • (1992) Gen Pharmacol , vol.23 , pp. 1205-1216
    • De Sarro, G.1    Ascioti, C.2    di Paola, E.D.3    Vidal, M.J.4    De Sarro, A.5
  • 31
    • 0026757458 scopus 로고
    • Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine
    • De Sarro, G., Meldrum, B.S., De Sarro, A., Patel, S., Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine. Brain Res 591 (1992), 209–222.
    • (1992) Brain Res , vol.591 , pp. 209-222
    • De Sarro, G.1    Meldrum, B.S.2    De Sarro, A.3    Patel, S.4
  • 32
    • 0015891261 scopus 로고
    • Relationships between neurotransmitter metabolism and behaviour in seven inbred strains of mice
    • Tunnicliff, G., Wimer, C.C., Wimer, R.E., Relationships between neurotransmitter metabolism and behaviour in seven inbred strains of mice. Brain Res 61 (1973), 428–434.
    • (1973) Brain Res , vol.61 , pp. 428-434
    • Tunnicliff, G.1    Wimer, C.C.2    Wimer, R.E.3
  • 33
    • 0018388547 scopus 로고
    • Thyroid hormone influence on the susceptibility of mice to audiogenic seizures
    • Seyfried, T.N., Glaser, G.H., Yu, R.K., Thyroid hormone influence on the susceptibility of mice to audiogenic seizures. Science 205 (1979), 598–600.
    • (1979) Science , vol.205 , pp. 598-600
    • Seyfried, T.N.1    Glaser, G.H.2    Yu, R.K.3
  • 34
    • 0019827701 scopus 로고
    • Developmental changes in brain glucose, glycogen, phosphocreatine, and ATP levels in DBA/2J and C57BL/6J mice, and audiogenic seizures
    • Schreiber, R.A., Developmental changes in brain glucose, glycogen, phosphocreatine, and ATP levels in DBA/2J and C57BL/6J mice, and audiogenic seizures. J Neurochem 37 (1981), 655–661.
    • (1981) J Neurochem , vol.37 , pp. 655-661
    • Schreiber, R.A.1
  • 35
    • 0016310709 scopus 로고
    • Some age-dependent biochemical changes in mice susceptible to seizures
    • Hertz, L., Schousboe, A., Formby, B., Lennox-Buchthal, M., Some age-dependent biochemical changes in mice susceptible to seizures. Epilepsia 15 (1974), 619–631.
    • (1974) Epilepsia , vol.15 , pp. 619-631
    • Hertz, L.1    Schousboe, A.2    Formby, B.3    Lennox-Buchthal, M.4
  • 36
    • 0016837006 scopus 로고
    • Cerebral magnesium and sodium–potassium ATPase following audiogenic seizures in mice
    • Reichert, W.H., Cerebral magnesium and sodium–potassium ATPase following audiogenic seizures in mice. Exp Neurol 49 (1975), 596–600.
    • (1975) Exp Neurol , vol.49 , pp. 596-600
    • Reichert, W.H.1
  • 37
    • 0018832849 scopus 로고
    • Noradrenergic influences on sound-induced seizures
    • Horton, R., Anlezark, G., Meldrum, B., Noradrenergic influences on sound-induced seizures. J Pharmacol Exp Ther 214 (1980), 437–442.
    • (1980) J Pharmacol Exp Ther , vol.214 , pp. 437-442
    • Horton, R.1    Anlezark, G.2    Meldrum, B.3
  • 38
    • 0022526975 scopus 로고
    • Brain adrenoceptor binding sites in mice susceptible (DBA/2J) and resistant (C57 Bl/6) to audiogenic seizures
    • Jazrawi, S.P., Horton, R.W., Brain adrenoceptor binding sites in mice susceptible (DBA/2J) and resistant (C57 Bl/6) to audiogenic seizures. J Neurochem 47 (1986), 173–177.
    • (1986) J Neurochem , vol.47 , pp. 173-177
    • Jazrawi, S.P.1    Horton, R.W.2
  • 39
    • 75849137701 scopus 로고    scopus 로고
    • Abnormal serotonin receptor expression in DBA/2 mice associated with susceptibility to sudden death due to respiratory arrest
    • Uteshev, V.V., Tupal, S., Mhaskar, Y., Faingold, C.L., Abnormal serotonin receptor expression in DBA/2 mice associated with susceptibility to sudden death due to respiratory arrest. Epilepsy Res 88 (2010), 183–188.
    • (2010) Epilepsy Res , vol.88 , pp. 183-188
    • Uteshev, V.V.1    Tupal, S.2    Mhaskar, Y.3    Faingold, C.L.4
  • 41
    • 0019952387 scopus 로고
    • Anticonvulsant action of excitatory amino acid antagonists
    • Croucher, M.J., Collins, J.F., Meldrum, B.S., Anticonvulsant action of excitatory amino acid antagonists. Science 216 (1982), 899–901.
    • (1982) Science , vol.216 , pp. 899-901
    • Croucher, M.J.1    Collins, J.F.2    Meldrum, B.S.3
  • 42
    • 0030558233 scopus 로고    scopus 로고
    • Anticonvulsant effect of reduced NMDA receptor expression in audiogenic DBA/2 mice
    • Chapman, A.G., Woodburn, V.L., Woodruff, G.N., Meldrum, B.S., Anticonvulsant effect of reduced NMDA receptor expression in audiogenic DBA/2 mice. Epilepsy Res 26 (1996), 25–35.
    • (1996) Epilepsy Res , vol.26 , pp. 25-35
    • Chapman, A.G.1    Woodburn, V.L.2    Woodruff, G.N.3    Meldrum, B.S.4
  • 43
    • 0037304326 scopus 로고    scopus 로고
    • Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents
    • De Sarro, G., Ferreri, G., Gareri, P., Russo, E., De Sarro, A., Gitto, R., et al. Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents. Pharmacol Biochem Behav 74 (2003), 595–602.
    • (2003) Pharmacol Biochem Behav , vol.74 , pp. 595-602
    • De Sarro, G.1    Ferreri, G.2    Gareri, P.3    Russo, E.4    De Sarro, A.5    Gitto, R.6
  • 44
    • 0347915541 scopus 로고    scopus 로고
    • Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents
    • Ferreri, G., Chimirri, A., Russo, E., Gitto, R., Gareri, P., De Sarro, A., et al. Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents. Pharmacol Biochem Behav 77 (2004), 85–94.
    • (2004) Pharmacol Biochem Behav , vol.77 , pp. 85-94
    • Ferreri, G.1    Chimirri, A.2    Russo, E.3    Gitto, R.4    Gareri, P.5    De Sarro, A.6
  • 45
    • 1642397435 scopus 로고    scopus 로고
    • Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy
    • Russo, E., Constanti, A., Ferreri, G., Citraro, R., De Sarro, G., Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy. Neuropharmacology 46 (2004), 865–878.
    • (2004) Neuropharmacology , vol.46 , pp. 865-878
    • Russo, E.1    Constanti, A.2    Ferreri, G.3    Citraro, R.4    De Sarro, G.5
  • 46
    • 1642498133 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives
    • Gitto, R., Caruso, R., Orlando, V., Quartarone, S., Barreca, M.L., Ferreri, G., et al. Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives. Farmaco 59 (2004), 7–12.
    • (2004) Farmaco , vol.59 , pp. 7-12
    • Gitto, R.1    Caruso, R.2    Orlando, V.3    Quartarone, S.4    Barreca, M.L.5    Ferreri, G.6
  • 47
    • 2142726012 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines
    • Quartarone, S., Caruso, R., Orlando, V., Russo, E., De Sarro, G., Chimirri, A., Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines. Farmaco 59 (2004), 353–358.
    • (2004) Farmaco , vol.59 , pp. 353-358
    • Quartarone, S.1    Caruso, R.2    Orlando, V.3    Russo, E.4    De Sarro, G.5    Chimirri, A.6
  • 48
    • 0142183302 scopus 로고    scopus 로고
    • Glutamate metabotropic receptors as targets for drug therapy in epilepsy
    • Moldrich, R.X., Chapman, A.G., De Sarro, G., Meldrum, B.S., Glutamate metabotropic receptors as targets for drug therapy in epilepsy. Eur J Pharmacol 476 (2003), 3–16.
    • (2003) Eur J Pharmacol , vol.476 , pp. 3-16
    • Moldrich, R.X.1    Chapman, A.G.2    De Sarro, G.3    Meldrum, B.S.4
  • 49
    • 0025947358 scopus 로고
    • Anticonvulsant activity of two orally active competitive N-methyl-D-aspartate antagonists, CGP 37849 and CGP 39551, against sound-induced seizures in DBA/2 mice and photically induced myoclonus in Papio papio
    • Chapman, A.G., Graham, J.L., Patel, S., Meldrum, B.S., Anticonvulsant activity of two orally active competitive N-methyl-D-aspartate antagonists, CGP 37849 and CGP 39551, against sound-induced seizures in DBA/2 mice and photically induced myoclonus in Papio papio. Epilepsia 32 (1991), 578–587.
    • (1991) Epilepsia , vol.32 , pp. 578-587
    • Chapman, A.G.1    Graham, J.L.2    Patel, S.3    Meldrum, B.S.4
  • 50
    • 0025884961 scopus 로고
    • The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy
    • Smith, S.E., Durmuller, N., Meldrum, B.S., The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy. Eur J Pharmacol 201 (1991), 179–183.
    • (1991) Eur J Pharmacol , vol.201 , pp. 179-183
    • Smith, S.E.1    Durmuller, N.2    Meldrum, B.S.3
  • 51
    • 0027022288 scopus 로고
    • The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates
    • Meldrum, B.S., Craggs, M.D., Durmuller, N., Smith, S.E., Chapman, A.G., The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates. Epilepsy Res Suppl 9 (1992), 307–311.
    • (1992) Epilepsy Res Suppl , vol.9 , pp. 307-311
    • Meldrum, B.S.1    Craggs, M.D.2    Durmuller, N.3    Smith, S.E.4    Chapman, A.G.5
  • 52
    • 0028906491 scopus 로고
    • Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice
    • De Sarro, G., Ammendola, D., Nava, F., De Sarro, A., Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice. Brain Res 671 (1995), 131–140.
    • (1995) Brain Res , vol.671 , pp. 131-140
    • De Sarro, G.1    Ammendola, D.2    Nava, F.3    De Sarro, A.4
  • 53
    • 0030250472 scopus 로고    scopus 로고
    • 1,4-Benzodiazepine derivatives as anticonvulsant agents in DBA/2 mice
    • De Sarro, G., Gitto, R., Rizzo, M., Zappia, M., De Sarro, A., 1,4-Benzodiazepine derivatives as anticonvulsant agents in DBA/2 mice. Gen Pharmacol 27 (1996), 935–941.
    • (1996) Gen Pharmacol , vol.27 , pp. 935-941
    • De Sarro, G.1    Gitto, R.2    Rizzo, M.3    Zappia, M.4    De Sarro, A.5
  • 54
    • 0030272388 scopus 로고    scopus 로고
    • Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice
    • De Sarro, G., Ongini, E., Bertorelli, R., Aguglia, U., De Sarro, A., Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice. Pharmacol Biochem Behav 55 (1996), 281–287.
    • (1996) Pharmacol Biochem Behav , vol.55 , pp. 281-287
    • De Sarro, G.1    Ongini, E.2    Bertorelli, R.3    Aguglia, U.4    De Sarro, A.5
  • 55
    • 0027533504 scopus 로고
    • Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex
    • De Sarro, G., Trimarchi, G.R., Sinopoli, S., Masuda, Y., De Sarro, A., Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol 24 (1993), 439–447.
    • (1993) Gen Pharmacol , vol.24 , pp. 439-447
    • De Sarro, G.1    Trimarchi, G.R.2    Sinopoli, S.3    Masuda, Y.4    De Sarro, A.5
  • 56
    • 33747031427 scopus 로고    scopus 로고
    • 3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents
    • De Luca, L., Gitto, R., Barreca, M.L., Caruso, R., Quartarone, S., Citraro, R., et al. 3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents. Arch Pharm (Weinheim) 339 (2006), 388–400.
    • (2006) Arch Pharm (Weinheim) , vol.339 , pp. 388-400
    • De Luca, L.1    Gitto, R.2    Barreca, M.L.3    Caruso, R.4    Quartarone, S.5    Citraro, R.6
  • 57
    • 77956329870 scopus 로고    scopus 로고
    • Potassium channel activity and glutamate uptake are impaired in astrocytes of seizure-susceptible DBA/2 mice
    • Inyushin, M., Kucheryavykh, L.Y., Kucheryavykh, Y.V., Nichols, C.G., Buono, R.J., Ferraro, T.N., et al. Potassium channel activity and glutamate uptake are impaired in astrocytes of seizure-susceptible DBA/2 mice. Epilepsia 51 (2010), 1707–1713.
    • (2010) Epilepsia , vol.51 , pp. 1707-1713
    • Inyushin, M.1    Kucheryavykh, L.Y.2    Kucheryavykh, Y.V.3    Nichols, C.G.4    Buono, R.J.5    Ferraro, T.N.6
  • 58
    • 0020213940 scopus 로고
    • Cerebral glutamic acid decarboxylase activity and gamma-aminobutyric acid concentrations in mice susceptible or resistant to audiogenic seizures
    • Sykes, C.C., Horton, R.W., Cerebral glutamic acid decarboxylase activity and gamma-aminobutyric acid concentrations in mice susceptible or resistant to audiogenic seizures. J Neurochem 39 (1982), 1489–1491.
    • (1982) J Neurochem , vol.39 , pp. 1489-1491
    • Sykes, C.C.1    Horton, R.W.2
  • 59
    • 0020183939 scopus 로고
    • gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice
    • Horton, R.W., Prestwich, S.A., Meldrum, B.S., gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice. J Neurochem 39 (1982), 864–870.
    • (1982) J Neurochem , vol.39 , pp. 864-870
    • Horton, R.W.1    Prestwich, S.A.2    Meldrum, B.S.3
  • 60
    • 0018951838 scopus 로고
    • Audiogenic seizures: increased benzodiazepine receptor binding in a susceptible strain of mice
    • Robertson, H.A., Audiogenic seizures: increased benzodiazepine receptor binding in a susceptible strain of mice. Eur J Pharmacol 66 (1980), 249–252.
    • (1980) Eur J Pharmacol , vol.66 , pp. 249-252
    • Robertson, H.A.1
  • 61
    • 0030255471 scopus 로고    scopus 로고
    • Azirino[1, 2-d][1, 4]benzodiazepine derivatives and related 1,4-benzodiazepines as anticonvulsant agents in DBA/2 mice
    • De Sarro, G., Chimirri, A., Zappala, M., Guisti, P., Lipartiti, M., De Sarro, A., Azirino[1, 2-d][1, 4]benzodiazepine derivatives and related 1,4-benzodiazepines as anticonvulsant agents in DBA/2 mice. Gen Pharmacol 27 (1996), 1155–1162.
    • (1996) Gen Pharmacol , vol.27 , pp. 1155-1162
    • De Sarro, G.1    Chimirri, A.2    Zappala, M.3    Guisti, P.4    Lipartiti, M.5    De Sarro, A.6
  • 62
    • 0030792653 scopus 로고    scopus 로고
    • Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice
    • De Sarro, G., Chimirri, A., McKernan, R., Quirk, K., Giusti, P., De Sarro, A., Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice. Pharmacol Biochem Behav 58 (1997), 281–289.
    • (1997) Pharmacol Biochem Behav , vol.58 , pp. 281-289
    • De Sarro, G.1    Chimirri, A.2    McKernan, R.3    Quirk, K.4    Giusti, P.5    De Sarro, A.6
  • 63
    • 18544409761 scopus 로고    scopus 로고
    • Benzodiazepine receptor affinities, behavioral, and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice
    • De Sarro, G., Carotti, A., Campagna, F., McKernan, R., Rizzo, M., Falconi, U., et al. Benzodiazepine receptor affinities, behavioral, and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice. Pharmacol Biochem Behav 65 (2000), 475–487.
    • (2000) Pharmacol Biochem Behav , vol.65 , pp. 475-487
    • De Sarro, G.1    Carotti, A.2    Campagna, F.3    McKernan, R.4    Rizzo, M.5    Falconi, U.6
  • 64
    • 0022361353 scopus 로고
    • Is adenosine an endogenous anticonvulsant?
    • Dragunow, M., Goddard, G.V., Laverty, R., Is adenosine an endogenous anticonvulsant?. Epilepsia 26 (1985), 480–487.
    • (1985) Epilepsia , vol.26 , pp. 480-487
    • Dragunow, M.1    Goddard, G.V.2    Laverty, R.3
  • 65
    • 0027332570 scopus 로고
    • Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice
    • Von Lubitz, D.K., Paul, I.A., Carter, M., Jacobson, K.A., Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice. Eur J Pharmacol 249 (1993), 265–270.
    • (1993) Eur J Pharmacol , vol.249 , pp. 265-270
    • Von Lubitz, D.K.1    Paul, I.A.2    Carter, M.3    Jacobson, K.A.4
  • 66
    • 0027370262 scopus 로고
    • Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility
    • Zhang, G., Franklin, P.H., Murray, T.F., Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility. J Pharmacol Exp Ther 264 (1993), 1415–1424.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 1415-1424
    • Zhang, G.1    Franklin, P.H.2    Murray, T.F.3
  • 67
    • 0032956116 scopus 로고    scopus 로고
    • Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice
    • De Sarro, G., De Sarro, A., Di Paola, E.D., Bertorelli, R., Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice. Eur J Pharmacol 371 (1999), 137–145.
    • (1999) Eur J Pharmacol , vol.371 , pp. 137-145
    • De Sarro, G.1    De Sarro, A.2    Di Paola, E.D.3    Bertorelli, R.4
  • 70
    • 0029828689 scopus 로고    scopus 로고
    • Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice
    • De Sarro, A., Naccari, F., Imperatore, C., De Sarro, G.B., Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice. J Antimicrob Chemother 38 (1996), 475–484.
    • (1996) J Antimicrob Chemother , vol.38 , pp. 475-484
    • De Sarro, A.1    Naccari, F.2    Imperatore, C.3    De Sarro, G.B.4
  • 72
    • 0028817342 scopus 로고
    • Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats
    • De Sarro, A., Ammendola, D., Zappala, M., Grasso, S., De Sarro, G.B., Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats. Antimicrob Agents Chemother 39 (1995), 232–237.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 232-237
    • De Sarro, A.1    Ammendola, D.2    Zappala, M.3    Grasso, S.4    De Sarro, G.B.5
  • 73
    • 84875171980 scopus 로고    scopus 로고
    • Pharmacodynamic potentiation of antiepileptic drugs’ effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice
    • Russo, E., Donato di Paola, E., Gareri, P., Siniscalchi, A., Labate, A., Gallelli, L., et al. Pharmacodynamic potentiation of antiepileptic drugs’ effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice. Pharmacol Res 70 (2013), 1–12.
    • (2013) Pharmacol Res , vol.70 , pp. 1-12
    • Russo, E.1    Donato di Paola, E.2    Gareri, P.3    Siniscalchi, A.4    Labate, A.5    Gallelli, L.6
  • 74
    • 84857036271 scopus 로고    scopus 로고
    • Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • De Sarro, G., Paola, E.D., Gratteri, S., Gareri, P., Rispoli, V., Siniscalchi, A., et al. Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacol Res 65 (2012), 285–296.
    • (2012) Pharmacol Res , vol.65 , pp. 285-296
    • De Sarro, G.1    Paola, E.D.2    Gratteri, S.3    Gareri, P.4    Rispoli, V.5    Siniscalchi, A.6
  • 75
    • 4544304001 scopus 로고    scopus 로고
    • Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models
    • Fischer, W., Kittner, H., Regenthal, R., Russo, E., De Sarro, G., Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models. J Neural Transm 111 (2004), 1121–1139.
    • (2004) J Neural Transm , vol.111 , pp. 1121-1139
    • Fischer, W.1    Kittner, H.2    Regenthal, R.3    Russo, E.4    De Sarro, G.5
  • 76
    • 0034634383 scopus 로고    scopus 로고
    • NMDA and AMPA/kainate receptors are involved in the anticonvulsant activity of riluzole in DBA/2 mice
    • De Sarro, G., Siniscalchi, A., Ferreri, G., Gallelli, L., De Sarro, A., NMDA and AMPA/kainate receptors are involved in the anticonvulsant activity of riluzole in DBA/2 mice. Eur J Pharmacol 408 (2000), 25–34.
    • (2000) Eur J Pharmacol , vol.408 , pp. 25-34
    • De Sarro, G.1    Siniscalchi, A.2    Ferreri, G.3    Gallelli, L.4    De Sarro, A.5
  • 77
    • 0024583999 scopus 로고
    • Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice
    • De Sarro, G.B., De Sarro, A., Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice. Neuropharmacology 28 (1989), 211–215.
    • (1989) Neuropharmacology , vol.28 , pp. 211-215
    • De Sarro, G.B.1    De Sarro, A.2
  • 78
    • 0029986072 scopus 로고    scopus 로고
    • Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice
    • De Sarro, G., Nava, F., Aguglia, U., De Sarro, A., Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice. Neuropharmacology 35 (1996), 153–158.
    • (1996) Neuropharmacology , vol.35 , pp. 153-158
    • De Sarro, G.1    Nava, F.2    Aguglia, U.3    De Sarro, A.4
  • 79
    • 0032557663 scopus 로고    scopus 로고
    • Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice
    • De Sarro, G., Spagnolo, C., Gareri, P., Gallelli, L., De Sarro, A., Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice. Eur J Pharmacol 349 (1998), 179–185.
    • (1998) Eur J Pharmacol , vol.349 , pp. 179-185
    • De Sarro, G.1    Spagnolo, C.2    Gareri, P.3    Gallelli, L.4    De Sarro, A.5
  • 80
    • 0035111693 scopus 로고    scopus 로고
    • Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • De Sarro, G., Di Paola, E.D., Conte, G., Pasculli, M.P., De Sarro, A., Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice. Naunyn Schmiedebergs Arch Pharmacol 363 (2001), 330–336.
    • (2001) Naunyn Schmiedebergs Arch Pharmacol , vol.363 , pp. 330-336
    • De Sarro, G.1    Di Paola, E.D.2    Conte, G.3    Pasculli, M.P.4    De Sarro, A.5
  • 81
    • 34447330442 scopus 로고    scopus 로고
    • Influence of levetiracetam on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • Donato Di Paola, E., Gareri, P., Davoli, A., Gratteri, S., Scicchitano, F., Naccari, C., et al. Influence of levetiracetam on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice. Epilepsy Res 75 (2007), 112–121.
    • (2007) Epilepsy Res , vol.75 , pp. 112-121
    • Donato Di Paola, E.1    Gareri, P.2    Davoli, A.3    Gratteri, S.4    Scicchitano, F.5    Naccari, C.6
  • 82
    • 0346687567 scopus 로고    scopus 로고
    • Influence of carbenoxolone on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice
    • Gareri, P., Condorelli, D., Belluardo, N., Gratteri, S., Ferreri, G., Donato Di Paola, E., et al. Influence of carbenoxolone on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice. Eur J Pharmacol 484 (2004), 49–56.
    • (2004) Eur J Pharmacol , vol.484 , pp. 49-56
    • Gareri, P.1    Condorelli, D.2    Belluardo, N.3    Gratteri, S.4    Ferreri, G.5    Donato Di Paola, E.6
  • 83
    • 0024401954 scopus 로고
    • Ontogeny of sound-induced seizures in the genetically epilepsy-prone rat
    • Reigel, C.E., Jobe, P.C., Dailey, J.W., Savage, D.D., Ontogeny of sound-induced seizures in the genetically epilepsy-prone rat. Epilepsy Res 4 (1989), 63–71.
    • (1989) Epilepsy Res , vol.4 , pp. 63-71
    • Reigel, C.E.1    Jobe, P.C.2    Dailey, J.W.3    Savage, D.D.4
  • 84
    • 0024541548 scopus 로고
    • Neurobiology of seizure predisposition in the genetically epilepsy-prone rat
    • Dailey, J.W., Reigel, C.E., Mishra, P.K., Jobe, P.C., Neurobiology of seizure predisposition in the genetically epilepsy-prone rat. Epilepsy Res 3 (1989), 3–17.
    • (1989) Epilepsy Res , vol.3 , pp. 3-17
    • Dailey, J.W.1    Reigel, C.E.2    Mishra, P.K.3    Jobe, P.C.4
  • 85
    • 0030044716 scopus 로고    scopus 로고
    • Amygdala kindling of forebrain seizures and the occurrence of brainstem seizures in genetically epilepsy-prone rats
    • Coffey, L.L., Reith, M.E., Chen, N.H., Mishra, P.K., Jobe, P.C., Amygdala kindling of forebrain seizures and the occurrence of brainstem seizures in genetically epilepsy-prone rats. Epilepsia 37 (1996), 188–197.
    • (1996) Epilepsia , vol.37 , pp. 188-197
    • Coffey, L.L.1    Reith, M.E.2    Chen, N.H.3    Mishra, P.K.4    Jobe, P.C.5
  • 86
    • 0035737293 scopus 로고    scopus 로고
    • Penetrance and expressivity of genes involved in the development of epilepsy in the genetically epilepsy-prone rat (GEPR)
    • Kurtz, B.S., Lehman, J., Garlick, P., Amberg, J., Mishra, P.K., Dailey, J.W., et al. Penetrance and expressivity of genes involved in the development of epilepsy in the genetically epilepsy-prone rat (GEPR). J Neurogenet 15 (2001), 233–244.
    • (2001) J Neurogenet , vol.15 , pp. 233-244
    • Kurtz, B.S.1    Lehman, J.2    Garlick, P.3    Amberg, J.4    Mishra, P.K.5    Dailey, J.W.6
  • 87
    • 0023773223 scopus 로고
    • Sex-specific distinctions in audiogenic convulsions exhibited by severe seizure genetically epilepsy-prone rats (GEPR-9s)
    • Mishra, P.K., Dailey, J.W., Reigel, C.E., Tomsic, M.L., Jobe, P.C., Sex-specific distinctions in audiogenic convulsions exhibited by severe seizure genetically epilepsy-prone rats (GEPR-9s). Epilepsy Res 2 (1988), 309–316.
    • (1988) Epilepsy Res , vol.2 , pp. 309-316
    • Mishra, P.K.1    Dailey, J.W.2    Reigel, C.E.3    Tomsic, M.L.4    Jobe, P.C.5
  • 88
    • 0024588366 scopus 로고
    • Audiogenic convulsions in moderate seizure genetically epilepsy-prone rats (GEPR-3s)
    • Mishra, P.K., Dailey, J.W., Reigel, C.E., Jobe, P.C., Audiogenic convulsions in moderate seizure genetically epilepsy-prone rats (GEPR-3s). Epilepsy Res 3 (1989), 191–198.
    • (1989) Epilepsy Res , vol.3 , pp. 191-198
    • Mishra, P.K.1    Dailey, J.W.2    Reigel, C.E.3    Jobe, P.C.4
  • 89
    • 0032605967 scopus 로고    scopus 로고
    • Neuronal networks in the genetically epilepsy-prone rat
    • Faingold, C.L., Neuronal networks in the genetically epilepsy-prone rat. Adv Neurol 79 (1999), 311–321.
    • (1999) Adv Neurol , vol.79 , pp. 311-321
    • Faingold, C.L.1
  • 91
    • 0018305891 scopus 로고
    • Audiogenic seizure susceptible rats
    • Consroe, P., Picchioni, A., Chin, L., Audiogenic seizure susceptible rats. Fed Proc 38 (1979), 2411–2416.
    • (1979) Fed Proc , vol.38 , pp. 2411-2416
    • Consroe, P.1    Picchioni, A.2    Chin, L.3
  • 92
    • 0022515064 scopus 로고
    • Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat
    • Faingold, C.L., Gehlbach, G., Caspary, D.M., Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat. Exp Neurol 93 (1986), 145–159.
    • (1986) Exp Neurol , vol.93 , pp. 145-159
    • Faingold, C.L.1    Gehlbach, G.2    Caspary, D.M.3
  • 93
    • 33749683558 scopus 로고    scopus 로고
    • Three brief epileptic seizures reduce inhibitory synaptic currents, GABA(A) currents, and GABA(A)-receptor subunits
    • Evans, M.S., Cady, C.J., Disney, K.E., Yang, L., Laguardia, J.J., Three brief epileptic seizures reduce inhibitory synaptic currents, GABA(A) currents, and GABA(A)-receptor subunits. Epilepsia 47 (2006), 1655–1664.
    • (2006) Epilepsia , vol.47 , pp. 1655-1664
    • Evans, M.S.1    Cady, C.J.2    Disney, K.E.3    Yang, L.4    Laguardia, J.J.5
  • 94
    • 0023948799 scopus 로고
    • Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists
    • Meldrum, B., Millan, M., Patel, S., de Sarro, G., Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists. J Neural Transm 72 (1988), 191–200.
    • (1988) J Neural Transm , vol.72 , pp. 191-200
    • Meldrum, B.1    Millan, M.2    Patel, S.3    de Sarro, G.4
  • 95
    • 0026733428 scopus 로고
    • Repeated treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats
    • De Sarro, A., Trimarchi, G.R., Ammendola, D., De Sarro, G., Repeated treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats. Gen Pharmacol 23 (1992), 853–859.
    • (1992) Gen Pharmacol , vol.23 , pp. 853-859
    • De Sarro, A.1    Trimarchi, G.R.2    Ammendola, D.3    De Sarro, G.4
  • 96
    • 0027424839 scopus 로고
    • Only some anticonvulsants protect against seizures induced by aminophylline in quinolone-treated genetically epilepsy prone rats
    • De Sarro, A., Ammendola, D., Juliano, M., Gareri, P., De Sarro, G., Only some anticonvulsants protect against seizures induced by aminophylline in quinolone-treated genetically epilepsy prone rats. Gen Pharmacol 24 (1993), 1393–1401.
    • (1993) Gen Pharmacol , vol.24 , pp. 1393-1401
    • De Sarro, A.1    Ammendola, D.2    Juliano, M.3    Gareri, P.4    De Sarro, G.5
  • 97
    • 0033051140 scopus 로고    scopus 로고
    • Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats
    • De Sarro, G., Di Paola, E.D., Gareri, P., Gallelli, L., Scotto, G., De Sarro, A., Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats. Eur J Pharmacol 368 (1999), 149–159.
    • (1999) Eur J Pharmacol , vol.368 , pp. 149-159
    • De Sarro, G.1    Di Paola, E.D.2    Gareri, P.3    Gallelli, L.4    Scotto, G.5    De Sarro, A.6
  • 98
    • 0025161651 scopus 로고
    • Anticonvulsant properties of some calcium antagonists on sound-induced seizures in genetically epilepsy prone rats
    • De Sarro, G., De Sarro, A., Federico, F., Meldrum, B.S., Anticonvulsant properties of some calcium antagonists on sound-induced seizures in genetically epilepsy prone rats. Gen Pharmacol 21 (1990), 769–778.
    • (1990) Gen Pharmacol , vol.21 , pp. 769-778
    • De Sarro, G.1    De Sarro, A.2    Federico, F.3    Meldrum, B.S.4
  • 100
    • 0025777641 scopus 로고
    • Noradrenergic abnormalities in the central nervous system of seizure-naive genetically epilepsy-prone rats
    • Dailey, J.W., Mishra, P.K., Ko, K.H., Penny, J.E., Jobe, P.C., Noradrenergic abnormalities in the central nervous system of seizure-naive genetically epilepsy-prone rats. Epilepsia 32 (1991), 168–173.
    • (1991) Epilepsia , vol.32 , pp. 168-173
    • Dailey, J.W.1    Mishra, P.K.2    Ko, K.H.3    Penny, J.E.4    Jobe, P.C.5
  • 101
    • 0022779177 scopus 로고
    • Noradrenergic and serotonergic determinants of seizure susceptibility and severity in genetically epilepsy-prone rats
    • Jobe, P.C., Dailey, J.W., Reigel, C.E., Noradrenergic and serotonergic determinants of seizure susceptibility and severity in genetically epilepsy-prone rats. Life Sci 39 (1986), 775–782.
    • (1986) Life Sci , vol.39 , pp. 775-782
    • Jobe, P.C.1    Dailey, J.W.2    Reigel, C.E.3
  • 102
    • 0026593032 scopus 로고
    • Serotonergic abnormalities in the central nervous system of seizure-naive genetically epilepsy-prone rats
    • Dailey, J.W., Mishra, P.K., Ko, K.H., Penny, J.E., Jobe, P.C., Serotonergic abnormalities in the central nervous system of seizure-naive genetically epilepsy-prone rats. Life Sci 50 (1992), 319–326.
    • (1992) Life Sci , vol.50 , pp. 319-326
    • Dailey, J.W.1    Mishra, P.K.2    Ko, K.H.3    Penny, J.E.4    Jobe, P.C.5
  • 103
    • 0019953412 scopus 로고
    • Abnormalities in monoamine levels in the central nervous system of the genetically epilepsy-prone rat
    • Jobe, P.C., Laird, H.E. II, Ko, K.H., Ray, T., Dailey, J.W., Abnormalities in monoamine levels in the central nervous system of the genetically epilepsy-prone rat. Epilepsia 23 (1982), 359–366.
    • (1982) Epilepsia , vol.23 , pp. 359-366
    • Jobe, P.C.1    Laird, H.E.2    Ko, K.H.3    Ray, T.4    Dailey, J.W.5
  • 104
    • 0344197520 scopus 로고    scopus 로고
    • Morphological deficits in noradrenergic neurons in GEPR-9s stem from abnormalities in both the locus coeruleus and its target tissues
    • Ryu, J.R., Jobe, P.C., Milbrandt, J.C., Mishra, P.K., Clough, R.W., Browning, R.A., et al. Morphological deficits in noradrenergic neurons in GEPR-9s stem from abnormalities in both the locus coeruleus and its target tissues. Exp Neurol 156 (1999), 84–91.
    • (1999) Exp Neurol , vol.156 , pp. 84-91
    • Ryu, J.R.1    Jobe, P.C.2    Milbrandt, J.C.3    Mishra, P.K.4    Clough, R.W.5    Browning, R.A.6
  • 106
    • 0015536632 scopus 로고
    • Role of brain norepinephrine in audiogenic seizure in the rat
    • Jobe, P.C., Picchioni, A.L., Chin, L., Role of brain norepinephrine in audiogenic seizure in the rat. J Pharmacol Exp Ther 184 (1973), 1–10.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 1-10
    • Jobe, P.C.1    Picchioni, A.L.2    Chin, L.3
  • 107
    • 0021856427 scopus 로고
    • Anticonvulsant drugs and the genetically epilepsy-prone rat
    • Dailey, J.W., Jobe, P.C., Anticonvulsant drugs and the genetically epilepsy-prone rat. Fed Proc 44 (1985), 2640–2644.
    • (1985) Fed Proc , vol.44 , pp. 2640-2644
    • Dailey, J.W.1    Jobe, P.C.2
  • 108
    • 0033795958 scopus 로고    scopus 로고
    • Genetically epilepsy-prone rats (GEPRs) in drug research
    • Jobe, P.C., Dailey, J.W., Genetically epilepsy-prone rats (GEPRs) in drug research. CNS Drug Rev 6 (2000), 241–260.
    • (2000) CNS Drug Rev , vol.6 , pp. 241-260
    • Jobe, P.C.1    Dailey, J.W.2
  • 109
    • 0023186133 scopus 로고
    • Ontogeny of seizure incidence, latency, and severity in genetically epilepsy prone rats
    • Hjeresen, D.L., Franck, J.E., Amend, D.L., Ontogeny of seizure incidence, latency, and severity in genetically epilepsy prone rats. Dev Psychobiol 20 (1987), 355–363.
    • (1987) Dev Psychobiol , vol.20 , pp. 355-363
    • Hjeresen, D.L.1    Franck, J.E.2    Amend, D.L.3
  • 110
    • 0023690542 scopus 로고
    • Anatomical and behavioral analyses of the inheritance of audiogenic seizures in the progeny of genetically epilepsy-prone and Sprague–Dawley rats
    • Ribak, C.E., Roberts, R.C., Byun, M.Y., Kim, H.L., Anatomical and behavioral analyses of the inheritance of audiogenic seizures in the progeny of genetically epilepsy-prone and Sprague–Dawley rats. Epilepsy Res 2 (1988), 345–355.
    • (1988) Epilepsy Res , vol.2 , pp. 345-355
    • Ribak, C.E.1    Roberts, R.C.2    Byun, M.Y.3    Kim, H.L.4
  • 111
    • 0025878046 scopus 로고
    • Effects of age on seizure susceptibility in genetically epilepsy-prone rats (GEPR-9s)
    • Thompson, J.L., Carl, F.G., Holmes, G.L., Effects of age on seizure susceptibility in genetically epilepsy-prone rats (GEPR-9s). Epilepsia 32 (1991), 161–167.
    • (1991) Epilepsia , vol.32 , pp. 161-167
    • Thompson, J.L.1    Carl, F.G.2    Holmes, G.L.3
  • 112
    • 0024505184 scopus 로고
    • Developing genetically epilepsy-prone rats have an abnormal seizure response to flurothyl
    • Franck, J.E., Ginter, K.L., Schwartzkroin, P.A., Developing genetically epilepsy-prone rats have an abnormal seizure response to flurothyl. Epilepsia 30 (1989), 1–6.
    • (1989) Epilepsia , vol.30 , pp. 1-6
    • Franck, J.E.1    Ginter, K.L.2    Schwartzkroin, P.A.3
  • 113
    • 0025169742 scopus 로고
    • Effects of seizures on learning, memory, and behavior in the genetically epilepsy-prone rat
    • Holmes, G.L., Thompson, J.L., Marchi, T.A., Gabriel, P.S., Hogan, M.A., Carl, F.G., et al. Effects of seizures on learning, memory, and behavior in the genetically epilepsy-prone rat. Ann Neurol 27 (1990), 24–32.
    • (1990) Ann Neurol , vol.27 , pp. 24-32
    • Holmes, G.L.1    Thompson, J.L.2    Marchi, T.A.3    Gabriel, P.S.4    Hogan, M.A.5    Carl, F.G.6
  • 114
    • 0030249902 scopus 로고    scopus 로고
    • Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats
    • De Sarro, G., Di Paola, E.D., Aguglia, U., de Sarro, A., Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats. Pharmacol Biochem Behav 55 (1996), 39–48.
    • (1996) Pharmacol Biochem Behav , vol.55 , pp. 39-48
    • De Sarro, G.1    Di Paola, E.D.2    Aguglia, U.3    de Sarro, A.4
  • 115
    • 0028302236 scopus 로고
    • Blockade of GABA uptake with tiagabine inhibits audiogenic seizures and reduces neuronal firing in the inferior colliculus of the genetically epilepsy-prone rat
    • Faingold, C.L., Randall, M.E., Anderson, C.A., Blockade of GABA uptake with tiagabine inhibits audiogenic seizures and reduces neuronal firing in the inferior colliculus of the genetically epilepsy-prone rat. Exp Neurol 126 (1994), 225–232.
    • (1994) Exp Neurol , vol.126 , pp. 225-232
    • Faingold, C.L.1    Randall, M.E.2    Anderson, C.A.3
  • 116
    • 0029086889 scopus 로고
    • Anticonvulsant properties of D-20443 in genetically epilepsy-prone rats: prediction of clinical response
    • Dailey, J.W., Cheong, J.H., Ko, K.H., Adams-Curtis, L.E., Jobe, P.C., Anticonvulsant properties of D-20443 in genetically epilepsy-prone rats: prediction of clinical response. Neurosci Lett 195 (1995), 77–80.
    • (1995) Neurosci Lett , vol.195 , pp. 77-80
    • Dailey, J.W.1    Cheong, J.H.2    Ko, K.H.3    Adams-Curtis, L.E.4    Jobe, P.C.5
  • 117
    • 0027191022 scopus 로고
    • Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat
    • Smith, S.E., al-Zubaidy, Z.A., Chapman, A.G., Meldrum, B.S., Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat. Epilepsy Res 15 (1993), 101–111.
    • (1993) Epilepsy Res , vol.15 , pp. 101-111
    • Smith, S.E.1    al-Zubaidy, Z.A.2    Chapman, A.G.3    Meldrum, B.S.4
  • 118
    • 0032916535 scopus 로고    scopus 로고
    • Carbamazepine pharmacokinetics–pharmacodynamics in genetically epilepsy-prone rats
    • Graumlich, J.F., McLaughlin, R.G., Birkhahn, D., Shah, N., Burk, A., Jobe, P.C., et al. Carbamazepine pharmacokinetics–pharmacodynamics in genetically epilepsy-prone rats. Eur J Pharmacol 369 (1999), 305–311.
    • (1999) Eur J Pharmacol , vol.369 , pp. 305-311
    • Graumlich, J.F.1    McLaughlin, R.G.2    Birkhahn, D.3    Shah, N.4    Burk, A.5    Jobe, P.C.6
  • 119
    • 0033047613 scopus 로고    scopus 로고
    • Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid)
    • Chapman, A.G., Yip, P.K., Yap, J.S., Quinn, L.P., Tang, E., Harris, J.R., et al. Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). Eur J Pharmacol 368 (1999), 17–24.
    • (1999) Eur J Pharmacol , vol.368 , pp. 17-24
    • Chapman, A.G.1    Yip, P.K.2    Yap, J.S.3    Quinn, L.P.4    Tang, E.5    Harris, J.R.6
  • 120
    • 0030784439 scopus 로고    scopus 로고
    • Enhancement of the anticonvulsant effect of fluoxetine following blockade of 5-HT1A receptors
    • Browning, R.A., Wood, A.V., Merrill, M.A., Dailey, J.W., Jobe, P.C., Enhancement of the anticonvulsant effect of fluoxetine following blockade of 5-HT1A receptors. Eur J Pharmacol 336 (1997), 1–6.
    • (1997) Eur J Pharmacol , vol.336 , pp. 1-6
    • Browning, R.A.1    Wood, A.V.2    Merrill, M.A.3    Dailey, J.W.4    Jobe, P.C.5
  • 121
    • 0026596320 scopus 로고
    • Anticonvulsant activity of competitive antagonists of NMDA receptor in genetically epilepsy-prone rats
    • De Sarro, G., De Sarro, A., Anticonvulsant activity of competitive antagonists of NMDA receptor in genetically epilepsy-prone rats. Eur J Pharmacol 215 (1992), 221–229.
    • (1992) Eur J Pharmacol , vol.215 , pp. 221-229
    • De Sarro, G.1    De Sarro, A.2
  • 122
    • 0027390972 scopus 로고
    • Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-aspartate receptor in genetically epilepsy-prone rats: comparison with CPPene
    • De Sarro, G.B., De Sarro, A., Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-aspartate receptor in genetically epilepsy-prone rats: comparison with CPPene. Neuropharmacology 32 (1993), 51–58.
    • (1993) Neuropharmacology , vol.32 , pp. 51-58
    • De Sarro, G.B.1    De Sarro, A.2
  • 123
    • 0032807148 scopus 로고    scopus 로고
    • Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in genetically epilepsy-prone rats
    • De Sarro, G., Rizzo, M., Spagnolo, C., Gitto, R., De Sarro, A., Scotto, G., et al. Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in genetically epilepsy-prone rats. Pharmacol Biochem Behav 63 (1999), 621–627.
    • (1999) Pharmacol Biochem Behav , vol.63 , pp. 621-627
    • De Sarro, G.1    Rizzo, M.2    Spagnolo, C.3    Gitto, R.4    De Sarro, A.5    Scotto, G.6
  • 124
    • 0031764446 scopus 로고    scopus 로고
    • Relationship between anticonvulsant activity and plasma level of some 2,3-benzodiazepines in genetically epilepsy-prone rats
    • De Sarro, G., Rizzo, M., Sinopoli, V.A., Gitto, R., De Sarro, A., Zappala, M., et al. Relationship between anticonvulsant activity and plasma level of some 2,3-benzodiazepines in genetically epilepsy-prone rats. Pharmacol Biochem Behav 61 (1998), 215–220.
    • (1998) Pharmacol Biochem Behav , vol.61 , pp. 215-220
    • De Sarro, G.1    Rizzo, M.2    Sinopoli, V.A.3    Gitto, R.4    De Sarro, A.5    Zappala, M.6
  • 125
    • 9644294329 scopus 로고    scopus 로고
    • Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs)
    • Gareri, P., Condorelli, D., Belluardo, N., Russo, E., Loiacono, A., Barresi, V., et al. Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs). Neuropharmacology 47 (2004), 1205–1216.
    • (2004) Neuropharmacology , vol.47 , pp. 1205-1216
    • Gareri, P.1    Condorelli, D.2    Belluardo, N.3    Russo, E.4    Loiacono, A.5    Barresi, V.6
  • 126
    • 67349108332 scopus 로고    scopus 로고
    • Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat
    • N'Gouemo, P., Yasuda, R.P., Faingold, C.L., Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat. Brain Res 1270 (2009), 107–111.
    • (2009) Brain Res , vol.1270 , pp. 107-111
    • N'Gouemo, P.1    Yasuda, R.P.2    Faingold, C.L.3
  • 127
    • 70949097896 scopus 로고    scopus 로고
    • Seizure susceptibility is associated with altered protein expression of voltage-gated calcium channel subunits in inferior colliculus neurons of the genetically epilepsy-prone rat
    • N'Gouemo, P., Yasuda, R., Faingold, C.L., Seizure susceptibility is associated with altered protein expression of voltage-gated calcium channel subunits in inferior colliculus neurons of the genetically epilepsy-prone rat. Brain Res 1308 (2010), 153–157.
    • (2010) Brain Res , vol.1308 , pp. 153-157
    • N'Gouemo, P.1    Yasuda, R.2    Faingold, C.L.3
  • 128
    • 0022773449 scopus 로고
    • The genetically epilepsy-prone rat: an overview of seizure-prone characteristics and responsiveness to anticonvulsant drugs
    • Reigel, C.E., Dailey, J.W., Jobe, P.C., The genetically epilepsy-prone rat: an overview of seizure-prone characteristics and responsiveness to anticonvulsant drugs. Life Sci 39 (1986), 763–774.
    • (1986) Life Sci , vol.39 , pp. 763-774
    • Reigel, C.E.1    Dailey, J.W.2    Jobe, P.C.3
  • 129
    • 0029127983 scopus 로고
    • Further evidence of anticonvulsant role for 5-hydroxytryptamine in genetically epilepsy-prone rats
    • Yan, Q.S., Jobe, P.C., Dailey, J.W., Further evidence of anticonvulsant role for 5-hydroxytryptamine in genetically epilepsy-prone rats. Br J Pharmacol 115 (1995), 1314–1318.
    • (1995) Br J Pharmacol , vol.115 , pp. 1314-1318
    • Yan, Q.S.1    Jobe, P.C.2    Dailey, J.W.3
  • 130
    • 0027958856 scopus 로고
    • Role of serotonin in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats
    • Yan, Q.S., Jobe, P.C., Cheong, J.H., Ko, K.H., Dailey, J.W., Role of serotonin in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats. Naunyn Schmiedebergs Arch Pharmacol 350 (1994), 149–152.
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.350 , pp. 149-152
    • Yan, Q.S.1    Jobe, P.C.2    Cheong, J.H.3    Ko, K.H.4    Dailey, J.W.5
  • 131
    • 0029876438 scopus 로고    scopus 로고
    • Abnormalities in brain serotonin concentration, high-affinity uptake, and tryptophan hydroxylase activity in severe-seizure genetically epilepsy-prone rats
    • Statnick, M.A., Dailey, J.W., Jobe, P.C., Browning, R.A., Abnormalities in brain serotonin concentration, high-affinity uptake, and tryptophan hydroxylase activity in severe-seizure genetically epilepsy-prone rats. Epilepsia 37 (1996), 311–321.
    • (1996) Epilepsia , vol.37 , pp. 311-321
    • Statnick, M.A.1    Dailey, J.W.2    Jobe, P.C.3    Browning, R.A.4
  • 132
    • 79957951224 scopus 로고    scopus 로고
    • Preclinical activity profile of alpha-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy
    • Citraro, R., Scicchitano, F., De Fazio, S., Raggio, R., Mainardi, P., Perucca, E., et al. Preclinical activity profile of alpha-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. Epilepsy Res 95 (2011), 60–69.
    • (2011) Epilepsy Res , vol.95 , pp. 60-69
    • Citraro, R.1    Scicchitano, F.2    De Fazio, S.3    Raggio, R.4    Mainardi, P.5    Perucca, E.6
  • 134
    • 0026694722 scopus 로고
    • Evidence that carbamazepine and antiepilepsirine may produce a component of their anticonvulsant effects by activating serotonergic neurons in genetically epilepsy-prone rats
    • Yan, Q.S., Mishra, P.K., Burger, R.L., Bettendorf, A.F., Jobe, P.C., Dailey, J.W., Evidence that carbamazepine and antiepilepsirine may produce a component of their anticonvulsant effects by activating serotonergic neurons in genetically epilepsy-prone rats. J Pharmacol Exp Ther 261 (1992), 652–659.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 652-659
    • Yan, Q.S.1    Mishra, P.K.2    Burger, R.L.3    Bettendorf, A.F.4    Jobe, P.C.5    Dailey, J.W.6
  • 136
    • 0022372083 scopus 로고
    • Evaluation of the 5-hydroxytryptamine receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin in different rodent models of epilepsy
    • Loscher, W., Czuczwar, S.J., Evaluation of the 5-hydroxytryptamine receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin in different rodent models of epilepsy. Neurosci Lett 60 (1985), 201–206.
    • (1985) Neurosci Lett , vol.60 , pp. 201-206
    • Loscher, W.1    Czuczwar, S.J.2
  • 137
    • 29544438942 scopus 로고    scopus 로고
    • The serotonergic and noradrenergic effects of antidepressant drugs are anticonvulsant, not proconvulsant
    • Jobe, P.C., Browning, R.A., The serotonergic and noradrenergic effects of antidepressant drugs are anticonvulsant, not proconvulsant. Epilepsy Behav 7 (2005), 602–619.
    • (2005) Epilepsy Behav , vol.7 , pp. 602-619
    • Jobe, P.C.1    Browning, R.A.2
  • 138
    • 1842586129 scopus 로고    scopus 로고
    • Shared mechanisms of antidepressant and antiepileptic treatments: drugs and devices
    • Jobe, P.C., Shared mechanisms of antidepressant and antiepileptic treatments: drugs and devices. Clin EEG Neurosci 35 (2004), 25–37.
    • (2004) Clin EEG Neurosci , vol.35 , pp. 25-37
    • Jobe, P.C.1
  • 139
    • 84996180433 scopus 로고    scopus 로고
    • Current and future therapeutic opportunities in the comorbidity between the epilepsies and affective disorders
    • Jobe, P.C., Current and future therapeutic opportunities in the comorbidity between the epilepsies and affective disorders. Clin EEG Neurosci 35 (2004), 1–3.
    • (2004) Clin EEG Neurosci , vol.35 , pp. 1-3
    • Jobe, P.C.1
  • 140
    • 0242659198 scopus 로고    scopus 로고
    • Common pathogenic mechanisms between depression and epilepsy: an experimental perspective
    • Jobe, P.C., Common pathogenic mechanisms between depression and epilepsy: an experimental perspective. Epilepsy Behav 4:Suppl. 3 (2003), S14–S24.
    • (2003) Epilepsy Behav , vol.4 , pp. S14-S24
    • Jobe, P.C.1
  • 141
    • 1842429136 scopus 로고    scopus 로고
    • Affective disorder and epilepsy comorbidity: implications for development of treatments, preventions and diagnostic approaches
    • Jobe, P.C., Affective disorder and epilepsy comorbidity: implications for development of treatments, preventions and diagnostic approaches. Clin EEG Neurosci 35 (2004), 53–68.
    • (2004) Clin EEG Neurosci , vol.35 , pp. 53-68
    • Jobe, P.C.1
  • 142
    • 33646674597 scopus 로고    scopus 로고
    • Depression in epilepsy: a neurobiologic perspective
    • Kanner, A.M., Depression in epilepsy: a neurobiologic perspective. Epilepsy Curr 5 (2005), 21–27.
    • (2005) Epilepsy Curr , vol.5 , pp. 21-27
    • Kanner, A.M.1
  • 143
    • 0033303233 scopus 로고    scopus 로고
    • A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders
    • Jobe, P.C., Dailey, J.W., Wernicke, J.F., A noradrenergic and serotonergic hypothesis of the linkage between epilepsy and affective disorders. Crit Rev Neurobiol 13 (1999), 317–356.
    • (1999) Crit Rev Neurobiol , vol.13 , pp. 317-356
    • Jobe, P.C.1    Dailey, J.W.2    Wernicke, J.F.3
  • 144
    • 0026016031 scopus 로고
    • Responsiveness of genetically epilepsy-prone rats to aminophylline-induced seizures and interactions with quinolones
    • De Sarro, A., De Sarro, G.B., Responsiveness of genetically epilepsy-prone rats to aminophylline-induced seizures and interactions with quinolones. Neuropharmacology 30 (1991), 169–176.
    • (1991) Neuropharmacology , vol.30 , pp. 169-176
    • De Sarro, A.1    De Sarro, G.B.2
  • 146
    • 0025298910 scopus 로고
    • Electroshock- and pentylenetetrazol-induced seizures in genetically epilepsy-prone rats (GEPRs): differences in threshold and pattern
    • Browning, R.A., Wang, C., Lanker, M.L., Jobe, P.C., Electroshock- and pentylenetetrazol-induced seizures in genetically epilepsy-prone rats (GEPRs): differences in threshold and pattern. Epilepsy Res 6 (1990), 1–11.
    • (1990) Epilepsy Res , vol.6 , pp. 1-11
    • Browning, R.A.1    Wang, C.2    Lanker, M.L.3    Jobe, P.C.4
  • 147
    • 0025871290 scopus 로고
    • The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate
    • Millan, M.H., Wardley-Smith, B., Durmuller, N., Meldrum, B.S., The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate. Exp Neurol 112 (1991), 317–320.
    • (1991) Exp Neurol , vol.112 , pp. 317-320
    • Millan, M.H.1    Wardley-Smith, B.2    Durmuller, N.3    Meldrum, B.S.4
  • 148
    • 0021058551 scopus 로고
    • Increased susceptibility of audiogenic rats to barbital withdrawal convulsions
    • Bourn, W.M., Garrett, R.L., Increased susceptibility of audiogenic rats to barbital withdrawal convulsions. Pharmacol Biochem Behav 19 (1983), 839–841.
    • (1983) Pharmacol Biochem Behav , vol.19 , pp. 839-841
    • Bourn, W.M.1    Garrett, R.L.2
  • 149
    • 84930210412 scopus 로고    scopus 로고
    • Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats
    • Citraro, R., Leo, A., Aiello, R., Pugliese, M., Russo, E., De Sarro, G., Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats. Neurotherapeutics 12 (2015), 250–262.
    • (2015) Neurotherapeutics , vol.12 , pp. 250-262
    • Citraro, R.1    Leo, A.2    Aiello, R.3    Pugliese, M.4    Russo, E.5    De Sarro, G.6
  • 150
    • 0023044883 scopus 로고
    • The development of kindled seizures is accelerated in the genetically epilepsy-prone rat
    • Savage, D.D., Reigel, C.E., Jobe, P.C., The development of kindled seizures is accelerated in the genetically epilepsy-prone rat. Life Sci 39 (1986), 879–886.
    • (1986) Life Sci , vol.39 , pp. 879-886
    • Savage, D.D.1    Reigel, C.E.2    Jobe, P.C.3
  • 152
    • 0030560601 scopus 로고    scopus 로고
    • Neuroethological and morphological (Neo-Timm staining) correlates of limbic recruitment during the development of audiogenic kindling in seizure susceptible Wistar rats
    • Garcia-Cairasco, N., Wakamatsu, H., Oliveira, J.A., Gomes, E.L., Del Bel, E.A., Mello, L.E., Neuroethological and morphological (Neo-Timm staining) correlates of limbic recruitment during the development of audiogenic kindling in seizure susceptible Wistar rats. Epilepsy Res 26 (1996), 177–192.
    • (1996) Epilepsy Res , vol.26 , pp. 177-192
    • Garcia-Cairasco, N.1    Wakamatsu, H.2    Oliveira, J.A.3    Gomes, E.L.4    Del Bel, E.A.5    Mello, L.E.6
  • 153
    • 0027269912 scopus 로고
    • Reciprocal positive transfer between kindling of audiogenic seizures and electrical kindling of inferior colliculus
    • Hirsch, E., Maton, B., Vergnes, M., Depaulis, A., Marescaux, C., Reciprocal positive transfer between kindling of audiogenic seizures and electrical kindling of inferior colliculus. Epilepsy Res 15 (1993), 133–139.
    • (1993) Epilepsy Res , vol.15 , pp. 133-139
    • Hirsch, E.1    Maton, B.2    Vergnes, M.3    Depaulis, A.4    Marescaux, C.5
  • 154
    • 0030599169 scopus 로고    scopus 로고
    • Lack of development of tolerance to anticonvulsant effects of two excitatory amino acid antagonists, CGP [corrected] 37849 and CGP 39551 in genetically epilepsy-prone rats
    • De Sarro, G., De Sarro, A., Ammendola, D., Patel, S., Lack of development of tolerance to anticonvulsant effects of two excitatory amino acid antagonists, CGP [corrected] 37849 and CGP 39551 in genetically epilepsy-prone rats. Brain Res 734 (1996), 91–97.
    • (1996) Brain Res , vol.734 , pp. 91-97
    • De Sarro, G.1    De Sarro, A.2    Ammendola, D.3    Patel, S.4
  • 155
    • 77954498319 scopus 로고    scopus 로고
    • Therapeutic approaches to epileptogenesis—hope on the horizon
    • Pitkanen, A., Therapeutic approaches to epileptogenesis—hope on the horizon. Epilepsia 51:Suppl. 3 (2010), 2–17.
    • (2010) Epilepsia , vol.51 , pp. 2-17
    • Pitkanen, A.1
  • 156
    • 0026521540 scopus 로고
    • Repetition of audiogenic seizures in genetically epilepsy-prone rats induces cortical epileptiform activity and additional seizure behaviors
    • Naritoku, D.K., Mecozzi, L.B., Aiello, M.T., Faingold, C.L., Repetition of audiogenic seizures in genetically epilepsy-prone rats induces cortical epileptiform activity and additional seizure behaviors. Exp Neurol 115 (1992), 317–324.
    • (1992) Exp Neurol , vol.115 , pp. 317-324
    • Naritoku, D.K.1    Mecozzi, L.B.2    Aiello, M.T.3    Faingold, C.L.4
  • 157
    • 26944442451 scopus 로고    scopus 로고
    • Brainstem seizure severity regulates forebrain seizure expression in the audiogenic kindling model
    • Merrill, M.A., Clough, R.W., Jobe, P.C., Browning, R.A., Brainstem seizure severity regulates forebrain seizure expression in the audiogenic kindling model. Epilepsia 46 (2005), 1380–1388.
    • (2005) Epilepsia , vol.46 , pp. 1380-1388
    • Merrill, M.A.1    Clough, R.W.2    Jobe, P.C.3    Browning, R.A.4
  • 158
    • 84899155654 scopus 로고    scopus 로고
    • Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies
    • White, H.S., Loscher, W., Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies. Neurotherapeutics 11 (2014), 373–384.
    • (2014) Neurotherapeutics , vol.11 , pp. 373-384
    • White, H.S.1    Loscher, W.2
  • 159
    • 40949113606 scopus 로고    scopus 로고
    • Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats
    • Shin, E.J., Ko, K.H., Kim, W.K., Chae, J.S., Yen, T.P., Kim, H.J., et al. Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats. Neurochem Int 52 (2008), 1134–1147.
    • (2008) Neurochem Int , vol.52 , pp. 1134-1147
    • Shin, E.J.1    Ko, K.H.2    Kim, W.K.3    Chae, J.S.4    Yen, T.P.5    Kim, H.J.6
  • 160
    • 84865751728 scopus 로고    scopus 로고
    • The amygdala to periaqueductal gray pathway: plastic changes induced by audiogenic kindling and reversal by gabapentin
    • Tupal, S., Faingold, C.L., The amygdala to periaqueductal gray pathway: plastic changes induced by audiogenic kindling and reversal by gabapentin. Brain Res 1475 (2012), 71–79.
    • (2012) Brain Res , vol.1475 , pp. 71-79
    • Tupal, S.1    Faingold, C.L.2
  • 162
    • 0024449997 scopus 로고
    • Animal models of the epilepsies
    • Fisher, R.S., Animal models of the epilepsies. Brain Res Brain Res Rev 14 (1989), 245–278.
    • (1989) Brain Res Brain Res Rev , vol.14 , pp. 245-278
    • Fisher, R.S.1
  • 163
    • 0021331202 scopus 로고
    • Evaluation of anticonvulsant drugs in genetic animal models of epilepsy
    • Loscher, W., Meldrum, B.S., Evaluation of anticonvulsant drugs in genetic animal models of epilepsy. Fed Proc 43 (1984), 276–284.
    • (1984) Fed Proc , vol.43 , pp. 276-284
    • Loscher, W.1    Meldrum, B.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.