메뉴 건너뛰기




Volumn 61, Issue 3, 1998, Pages 215-220

Relationship between anticonvulsant activity and plasma level of some 2,3-benzodiazepines in genetically epilepsy-prone rats

Author keywords

2,3 Benzodiazepine; AMPA kainate antagonists; Epilepsy; Genetically epilepsy prone rats; Plasma level

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 3,5 DIHYDRO 7,8 DIMETHOXY 1 PHENYL 4H 2,3 BENZODIAZEPIN 4 ONE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMPA RECEPTOR; BENZODIAZEPINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0031764446     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00036-7     Document Type: Article
Times cited : (26)

References (30)
  • 1
    • 0025943535 scopus 로고
    • Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transiet forebrain ischemia in adult rats
    • Buchan, A. M.; Li, H.; Cho, S.; Pulsinelli, W. A.: Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transiet forebrain ischemia in adult rats. Neurosci. Lett. 132:255-258; 1991.
    • (1991) Neurosci. Lett. , vol.132 , pp. 255-258
    • Buchan, A.M.1    Li, H.2    Cho, S.3    Pulsinelli, W.A.4
  • 2
    • 0025789026 scopus 로고
    • The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466 in mice
    • Chapman, A. G.; Smith, S. E.; Meldrum, B. S.: The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466 in mice. Epilepsy Res. 9:92-96; 1991.
    • (1991) Epilepsy Res. , vol.9 , pp. 92-96
    • Chapman, A.G.1    Smith, S.E.2    Meldrum, B.S.3
  • 6
    • 0026016031 scopus 로고
    • Responsiveness of genetically epilepsy prone rats to aminophylline-induced seizures and interactions with quinolones
    • De Sarro, A.; De Sarro, G. B.: Responsiveness of genetically epilepsy prone rats to aminophylline-induced seizures and interactions with quinolones. Neuropharmacology 30:169-176; 1991.
    • (1991) Neuropharmacology , vol.30 , pp. 169-176
    • De Sarro, A.1    De Sarro, G.B.2
  • 7
    • 0026596320 scopus 로고
    • Anticonvulsant activity of competitive antagonists of NMDA receptor in genetically epilepsy prone rats
    • De Sarro, G. B.; De Sarro, A.: Anticonvulsant activity of competitive antagonists of NMDA receptor in genetically epilepsy prone rats. Eur. J. Pharmacol. 215:221-229; 1992.
    • (1992) Eur. J. Pharmacol. , vol.215 , pp. 221-229
    • De Sarro, G.B.1    De Sarro, A.2
  • 8
    • 0027390972 scopus 로고
    • Anticonvulsant properties of non competitive antagonists of NMDA receptor in genetically epilepsy prone rats. Comparison with CPPene
    • De Sarro, G. B.; De Sarro, A.: Anticonvulsant properties of non competitive antagonists of NMDA receptor in genetically epilepsy prone rats. Comparison with CPPene. Neuropharmacology 32:51-58; 1993.
    • (1993) Neuropharmacology , vol.32 , pp. 51-58
    • De Sarro, G.B.1    De Sarro, A.2
  • 9
    • 0028021395 scopus 로고
    • Excitatory amino acid neurotransmission through both NMDA and nonNMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice
    • De Sarro, G. B.; Ongini, E.; Bertorelli, R.; Aguglia, U.; De Sarro, A.: Excitatory amino acid neurotransmission through both NMDA and nonNMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. Eur. J. Pharmacol. 262:11-19; 1994.
    • (1994) Eur. J. Pharmacol. , vol.262 , pp. 11-19
    • De Sarro, G.B.1    Ongini, E.2    Bertorelli, R.3    Aguglia, U.4    De Sarro, A.5
  • 10
    • 0030249902 scopus 로고    scopus 로고
    • Tolerance to anticonvulsant effects of clobazam, diazepam and clonazepam in genetically epilepsy prone rats
    • De Sarro, G. B.; Donato Di Paola, E.; Aguglia, U.; De Sarro, A.: Tolerance to anticonvulsant effects of clobazam, diazepam and clonazepam in genetically epilepsy prone rats. Pharmacol. Biochem. Behav. 55:39-48; 1996.
    • (1996) Pharmacol. Biochem. Behav. , vol.55 , pp. 39-48
    • De Sarro, G.B.1    Donato Di Paola, E.2    Aguglia, U.3    De Sarro, A.4
  • 11
    • 0026733428 scopus 로고
    • Repetitive treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats
    • De Sarro, A.; Trimarchi, G. R.; Ammendola, D.; De Sarro, G. B.: Repetitive treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats. Gen. Pharmacol. 23:853-859; 1992.
    • (1992) Gen. Pharmacol. , vol.23 , pp. 853-859
    • De Sarro, A.1    Trimarchi, G.R.2    Ammendola, D.3    De Sarro, G.B.4
  • 12
    • 0027533504 scopus 로고
    • Anticonvulsant effects of U-54494a and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: A possible involvement of glycine/NMDa receptor complex
    • De Sarro, G. B.; Trimarchi, G. R.; Sinopoli, S.; Masuda, Y.; De Sarro, A.: Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: A possible involvement of glycine/NMDA receptor complex. Gen. Pharmacol. 24:439-447; 1993.
    • (1993) Gen. Pharmacol. , vol.24 , pp. 439-447
    • De Sarro, G.B.1    Trimarchi, G.R.2    Sinopoli, S.3    Masuda, Y.4    De Sarro, A.5
  • 13
    • 70449177837 scopus 로고
    • A note on a simple apparatus for detecting neurological deficit in rats and mice
    • Dunham, N. W.; Miya T. S.: A note on a simple apparatus for detecting neurological deficit in rats and mice. J. Am. Pharm. Assoc. 46:208-209; 1957.
    • (1957) J. Am. Pharm. Assoc. , vol.46 , pp. 208-209
    • Dunham, N.W.1    Miya, T.S.2
  • 14
    • 0026625606 scopus 로고
    • Regional cerebral protein synthesis after transient ischemia in the rat: Effect of the AMPA antagonist NBQX
    • Frank, L.; Bruhn, T.; Diemer, N. H.: Regional cerebral protein synthesis after transient ischemia in the rat: Effect of the AMPA antagonist NBQX. Neurosci. Lett. 140:108-112; 1992.
    • (1992) Neurosci. Lett. , vol.140 , pp. 108-112
    • Frank, L.1    Bruhn, T.2    Diemer, N.H.3
  • 15
    • 0025169357 scopus 로고
    • The epileptiform activity induced by 4-aminopyridine in rat amygdala slices: Antagonism by non-N-methyl-D-aspartate receptor antagonists
    • Gean, P. W.: The epileptiform activity induced by 4-aminopyridine in rat amygdala slices: Antagonism by non-N-methyl-D-aspartate receptor antagonists. Brain Res. 530:251-256; 1990.
    • (1990) Brain Res. , vol.530 , pp. 251-256
    • Gean, P.W.1
  • 16
    • 0002396599 scopus 로고
    • Pharmacology of audiogenic seizures
    • Brown, R. D.; Daigneault, E. A., eds. New York: John Wiley
    • Jobe, P. C.: Pharmacology of audiogenic seizures. In: Brown, R. D.; Daigneault, E. A., eds. Pharmacology of hearing. Experiment and clinical bases. New York: John Wiley; 1981:271-304.
    • (1981) Pharmacology of Hearing. Experiment and Clinical Bases , pp. 271-304
    • Jobe, P.C.1
  • 17
    • 0026074931 scopus 로고
    • The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys
    • Klockgether, T.; Turski, L.; Honore, T.; Zhang, Z. M.; Gash, D. M.; Kurlan, R.; Greenamyre, J. T.: The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys. Ann. Neurol. 30:717-723; 1991.
    • (1991) Ann. Neurol. , vol.30 , pp. 717-723
    • Klockgether, T.1    Turski, L.2    Honore, T.3    Zhang, Z.M.4    Gash, D.M.5    Kurlan, R.6    Greenamyre, J.T.7
  • 18
    • 84951384024 scopus 로고
    • A simplified method of evaluating dose-effects experiments
    • Litchfield, J. F.; Wilcoxon, F.: A simplified method of evaluating dose-effects experiments. J. Pharmacol. Exp. Ther. 96:99-113; 1949.
    • (1949) J. Pharmacol. Exp. Ther. , vol.96 , pp. 99-113
    • Litchfield, J.F.1    Wilcoxon, F.2
  • 19
    • 0023948799 scopus 로고
    • Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists
    • Meldrum, B. S.; Millan, M.; Patel, S.; De Sarro, G. B.: Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists. J. Neural Transm. 72:191-198; 1988.
    • (1988) J. Neural Transm. , vol.72 , pp. 191-198
    • Meldrum, B.S.1    Millan, M.2    Patel, S.3    De Sarro, G.B.4
  • 20
    • 0026562858 scopus 로고
    • Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala
    • Rainnie, D. G.; Asprodini, E. K.; Shinnick-Gallagher, P.: Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala. J. Neurophysiol. 67:443-454; 1992.
    • (1992) J. Neurophysiol. , vol.67 , pp. 443-454
    • Rainnie, D.G.1    Asprodini, E.K.2    Shinnick-Gallagher, P.3
  • 22
    • 0027176541 scopus 로고
    • Therapeutic potential of excitatory amino acid antagonists: Channel blockers and 2,3-benzodiazepines
    • Rogawski, M.: Therapeutic potential of excitatory amino acid antagonists: Channel blockers and 2,3-benzodiazepines. Trends Pharmacol. Sci. 14:325-331; 1993.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 325-331
    • Rogawski, M.1
  • 23
    • 0025117827 scopus 로고
    • 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline: A neuroprotectant for cerebral ischemia
    • Sheardown, M. J.; Nielsen, E. O.; Hansen, A. J.; Jacobsen, P.; Honore, T.: 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline: A neuroprotectant for cerebral ischemia. Science 247:571-574; 1991.
    • (1991) Science , vol.247 , pp. 571-574
    • Sheardown, M.J.1    Nielsen, E.O.2    Hansen, A.J.3    Jacobsen, P.4    Honore, T.5
  • 24
    • 0025884961 scopus 로고
    • The non-N-methyl-D-aspartate antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy
    • Smith, S. E.; Durmuller, N.; Meldrum, B. S.: The non-N-methyl-D-aspartate antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy. Eur. J. Pharmacol. 201:179-183; 1991.
    • (1991) Eur. J. Pharmacol. , vol.201 , pp. 179-183
    • Smith, S.E.1    Durmuller, N.2    Meldrum, B.S.3
  • 25
    • 0026623418 scopus 로고
    • Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat
    • Smith, S. E.; Meldrum, B. S.: Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat. Stroke 23:861-864; 1992.
    • (1992) Stroke , vol.23 , pp. 861-864
    • Smith, S.E.1    Meldrum, B.S.2
  • 26
    • 0024317594 scopus 로고
    • Electrophysiological studies with 2,3-benzodiazepine muscle relaxant: GYKI 52466
    • Tarnawa, I.; Farkas, S.; Berzsenyi, P.; Pataki, A.; Andreasi, F.: Electrophysiological studies with 2,3-benzodiazepine muscle relaxant: GYKI 52466. Eur. J. Pharmacol. 167:193-199; 1989.
    • (1989) Eur. J. Pharmacol. , vol.167 , pp. 193-199
    • Tarnawa, I.1    Farkas, S.2    Berzsenyi, P.3    Pataki, A.4    Andreasi, F.5
  • 27
    • 0002547153 scopus 로고
    • GYKI 52466 an inhibitor of spinal reflexes is a potent quisqualate antagonist
    • Lube, G.; Resental, G. A., eds. Escona: Leiden
    • Tarnawa, I.; Engberg, I.; Flatman, J. A.: GYKI 52466 an inhibitor of spinal reflexes is a potent quisqualate antagonist. In: Lube, G.; Resental, G. A., eds. Amino acids: Chemistry, biology and medicine. Escona: Leiden; 1990:538-546.
    • (1990) Amino Acids: Chemistry, Biology and Medicine , pp. 538-546
    • Tarnawa, I.1    Engberg, I.2    Flatman, J.A.3
  • 28
    • 0026668693 scopus 로고
    • NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy-piperazinpropyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats
    • Wachtel, H.; Kunow, M.; Loeschman, P. A.: NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy-piperazinpropyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats. Neurosci. Lett. 142:179-182; 1992.
    • (1992) Neurosci. Lett. , vol.142 , pp. 179-182
    • Wachtel, H.1    Kunow, M.2    Loeschman, P.A.3
  • 29
    • 0026542967 scopus 로고
    • NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema
    • Westergren, I.; Johansson, B. B.: NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema. Brain Res. 573:324-326; 1992.
    • (1992) Brain Res. , vol.573 , pp. 324-326
    • Westergren, I.1    Johansson, B.B.2
  • 30
    • 0027242080 scopus 로고
    • Anticonvulsant activity of AMPA/kainate antagonists: Comparison of GYKI 52466 and NBQX in maximal electroshock and chemoconvulsant seizure models
    • Yamaguchi, S.; Donevan, S. D.; Rogawski, M. A.: Anticonvulsant activity of AMPA/kainate antagonists: Comparison of GYKI 52466 and NBQX in maximal electroshock and chemoconvulsant seizure models. Epilepsy Res. 15:179-184; 1993.
    • (1993) Epilepsy Res. , vol.15 , pp. 179-184
    • Yamaguchi, S.1    Donevan, S.D.2    Rogawski, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.