-
3
-
-
0025064068
-
Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor
-
Ali H, Cunha-Melo JR, Saul WF, Beaven MA (1990) Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor. J Biol Chem 265:745-753
-
(1990)
J Biol Chem
, vol.265
, pp. 745-753
-
-
Ali, H.1
Cunha-Melo, J.R.2
Saul, W.F.3
Beaven, M.A.4
-
4
-
-
0025939086
-
Methylxanthines block antigen-induced responses in RBL-2H3 cells indipendently of adenosine receptors or cyclic AMP: Evidence for inhibition of antigen binding to IgE
-
Ali H, Muller CE, Daly JW, Beaven MA (1991) Methylxanthines block antigen-induced responses in RBL-2H3 cells indipendently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE. J Pharmacol Exp Ther 258:954-962
-
(1991)
J Pharmacol Exp Ther
, vol.258
, pp. 954-962
-
-
Ali, H.1
Muller, C.E.2
Daly, J.W.3
Beaven, M.A.4
-
6
-
-
0023205572
-
Proconvulsant actions of theophylline and caffeine in the hippocampus: Implications for the management of temporale lobe epilepsy
-
Ault B, Olney MA, Joyner JL, Boyer CE, Notrica MA, Soroko FE, Wang CM (1987) Proconvulsant actions of theophylline and caffeine in the hippocampus: implications for the management of temporale lobe epilepsy. Brain Res 426:93-102
-
(1987)
Brain Res
, vol.426
, pp. 93-102
-
-
Ault, B.1
Olney, M.A.2
Joyner, J.L.3
Boyer, C.E.4
Notrica, M.A.5
Soroko, F.E.6
Wang, C.M.7
-
8
-
-
0021250356
-
Anticonvulsant effects of adenosine analogues on amygaloid-kindled seizures in rats
-
Barraco RA, Swanson TH, Phillis JW, Berman RF (1984) Anticonvulsant effects of adenosine analogues on amygaloid-kindled seizures in rats. Neurosci Lett 46: 317-322
-
(1984)
Neurosci Lett
, vol.46
, pp. 317-322
-
-
Barraco, R.A.1
Swanson, T.H.2
Phillis, J.W.3
Berman, R.F.4
-
9
-
-
0001477154
-
A simple assessment of partition data for correlating structure and biological activity using thin-layer chromatography
-
Boyce CBC, Milborrow BV (1965) A simple assessment of partition data for correlating structure and biological activity using thin-layer chromatography. Nature 208:537-539
-
(1965)
Nature
, vol.208
, pp. 537-539
-
-
Boyce, C.B.C.1
Milborrow, B.V.2
-
11
-
-
0023786298
-
Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors
-
Cirillo R, Barone D, Franzone JS (1988) Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther 295:221-237
-
(1988)
Arch Int Pharmacodyn Ther
, vol.295
, pp. 221-237
-
-
Cirillo, R.1
Barone, D.2
Franzone, J.S.3
-
12
-
-
0021179327
-
Adenosine decreases aspartate and glutamate release from rat hippocampal slices
-
Corradetti R, Lo Conte R, Moroni F, Passani MB, Pepeu G (1984) Adenosine decreases aspartate and glutamate release from rat hippocampal slices. Eur J Pharmacol 104:19-26
-
(1984)
Eur J Pharmacol
, vol.104
, pp. 19-26
-
-
Corradetti, R.1
Lo Conte, R.2
Moroni, F.3
Passani, M.B.4
Pepeu, G.5
-
13
-
-
0026447601
-
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: An EEG and behavioural study
-
Cutrufo C, Bortot L, Giachetti A, Manzini S (1992) Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. Eur J Pharmacol 222:1-6
-
(1992)
Eur J Pharmacol
, vol.222
, pp. 1-6
-
-
Cutrufo, C.1
Bortot, L.2
Giachetti, A.3
Manzini, S.4
-
14
-
-
0023200140
-
Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats
-
Czuczwar SJ, Jackel R, Loscher W (1987a) Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats. Epilepsy Res 1:234-238
-
(1987)
Epilepsy Res
, vol.1
, pp. 234-238
-
-
Czuczwar, S.J.1
Jackel, R.2
Loscher, W.3
-
15
-
-
0023244915
-
Effect of aminophylline and enprofylline on the protective efficacy of common antiepileptic drugs against electroconvulsions in mice
-
Czuczwar SJ, Kleinrok Z, Turski L, Turski WA (1987b) Effect of aminophylline and enprofylline on the protective efficacy of common antiepileptic drugs against electroconvulsions in mice. Epilepsia 28:383-386
-
(1987)
Epilepsia
, vol.28
, pp. 383-386
-
-
Czuczwar, S.J.1
Kleinrok, Z.2
Turski, L.3
Turski, W.A.4
-
16
-
-
0025353385
-
Influence of different methylxanthines on the anticonvulsant action of common antiepileptic drugs in mice
-
Czuczwar SJ, Gasior M, Janusz W, Szczepanik B, Wlodarczyk D, Kleinrok Z (1990) Influence of different methylxanthines on the anticonvulsant action of common antiepileptic drugs in mice. Epilepsia 31:318-323
-
(1990)
Epilepsia
, vol.31
, pp. 318-323
-
-
Czuczwar, S.J.1
Gasior, M.2
Janusz, W.3
Szczepanik, B.4
Wlodarczyk, D.5
Kleinrok, Z.6
-
17
-
-
0019829170
-
Adenosine receptors in the central nervous system, relationship to the central actions of methylxanthines
-
Daly JW, Bruns RF, Snyder SH (1981) Adenosine receptors in the central nervous system, relationship to the central actions of methylxanthines. Life Sci 28:2083-2097
-
(1981)
Life Sci
, vol.28
, pp. 2083-2097
-
-
Daly, J.W.1
Bruns, R.F.2
Snyder, S.H.3
-
18
-
-
0022544144
-
Analogues of caffeine and theophylline: Effect of structural alterations on affinity at adenosine receptors
-
Daly JW, Padgett W, Shamim MT (1985) Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. J Med Chem 29:1305-1308
-
(1985)
J Med Chem
, vol.29
, pp. 1305-1308
-
-
Daly, J.W.1
Padgett, W.2
Shamim, M.T.3
-
19
-
-
0026016031
-
Responsiveness of genetically epilepsy-prone rats to aminophylline-induced seizures and interactions with quinolones
-
De Sarro A, De Sarro GB (1991) Responsiveness of genetically epilepsy-prone rats to aminophylline-induced seizures and interactions with quinolones. Neuropharmacology 30:169-176
-
(1991)
Neuropharmacology
, vol.30
, pp. 169-176
-
-
De Sarro, A.1
De Sarro, G.B.2
-
20
-
-
0025975999
-
Anticonvulsant action of 2-chloroadenosine injected focally into the inferior colliculus and substantia nigra
-
De Sarro G, De Sarro A, Meldrum BS (1991) Anticonvulsant action of 2-chloroadenosine injected focally into the inferior colliculus and substantia nigra. Eur J Pharmacol 194:145-152
-
(1991)
Eur J Pharmacol
, vol.194
, pp. 145-152
-
-
De Sarro, G.1
De Sarro, A.2
Meldrum, B.S.3
-
21
-
-
8544259118
-
Effects of compounds acting on different adenosine receptor subtypes on audiogenic seizures in DBA/2 mice
-
abstract book
-
De Sarro G, Di Paola ED, De Sarro A (1996a) Effects of compounds acting on different adenosine receptor subtypes on audiogenic seizures in DBA/2 mice. BPS Winter Meeting, abstract book, P222
-
(1996)
BPS Winter Meeting
-
-
De Sarro, G.1
Di Paola, E.D.2
De Sarro, A.3
-
23
-
-
0025160941
-
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline
-
Dragunow M (1990) Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline. Pharmacol Biochem Behav 36: 751-755
-
(1990)
Pharmacol Biochem Behav
, vol.36
, pp. 751-755
-
-
Dragunow, M.1
-
24
-
-
0022361353
-
Is adenosine an endogenous anticonvulsant?
-
Dragunow M, Goddard GV, Laverty R (1985) Is adenosine an endogenous anticonvulsant? Epilepsia 26:480-487
-
(1985)
Epilepsia
, vol.26
, pp. 480-487
-
-
Dragunow, M.1
Goddard, G.V.2
Laverty, R.3
-
25
-
-
0020072995
-
Sedative and anticonvulsant effects of adenosine analogs in mouse and rat
-
Dunwiddie TV, Worth T (1982) Sedative and anticonvulsant effects of adenosine analogs in mouse and rat. J Pharmacol Exp Ther 220: 70-76
-
(1982)
J Pharmacol Exp Ther
, vol.220
, pp. 70-76
-
-
Dunwiddie, T.V.1
Worth, T.2
-
27
-
-
49249149792
-
Are the actions of methylxanthines due to antagonism of adenosine?
-
Fredholm BB (1980) Are the actions of methylxanthines due to antagonism of adenosine? Trends Pharmacol Sci 1:129-132
-
(1980)
Trends Pharmacol Sci
, vol.1
, pp. 129-132
-
-
Fredholm, B.B.1
-
28
-
-
0018875426
-
Modulation of neurotransmission by purine nucleotides and nucleosides
-
Fredholm BB, Hedquist P (1980) Modulation of neurotransmission by purine nucleotides and nucleosides. Biochem Pharmacol 29:1635-1645
-
(1980)
Biochem Pharmacol
, vol.29
, pp. 1635-1645
-
-
Fredholm, B.B.1
Hedquist, P.2
-
29
-
-
0027263305
-
Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number
-
Georgiev V, Johansson B, Fredholm BB (1993) Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number. Brain Res 612:271-277
-
(1993)
Brain Res
, vol.612
, pp. 271-277
-
-
Georgiev, V.1
Johansson, B.2
Fredholm, B.B.3
-
31
-
-
0026520040
-
Adenosine receptors: Pharmacology, structure activity relationships, and therapeutic potential
-
Jacobson KA, van Galen PJM, Williams M (1992) Adenosine receptors: pharmacology, structure activity relationships, and therapeutic potential. J Med Chem 35:407-422
-
(1992)
J Med Chem
, vol.35
, pp. 407-422
-
-
Jacobson, K.A.1
Van Galen, P.J.M.2
Williams, M.3
-
32
-
-
0027362627
-
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors
-
Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Muller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W (1993) Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. J Med Chem 36:2639-2644
-
(1993)
J Med Chem
, vol.36
, pp. 2639-2644
-
-
Jacobson, K.A.1
Shi, D.2
Gallo-Rodriguez, C.3
Manning, M.4
Muller, C.5
Daly, J.W.6
Neumeyer, J.L.7
Kiriasis, L.8
Pfleiderer, W.9
-
35
-
-
84951384024
-
A simplified method of evaluation dose-effect experiments
-
Litchfield JT, Wilcoxon F (1949) A simplified method of evaluation dose-effect experiments. J Pharmacol Exp Ther 96: 99-113
-
(1949)
J Pharmacol Exp Ther
, vol.96
, pp. 99-113
-
-
Litchfield, J.T.1
Wilcoxon, F.2
-
37
-
-
0025132553
-
Pharmacodynamic profile of isbufylline, a new antibronchospastic xanthine devoid of central excitatory actions
-
Manzini S, Meini S, Giachetti A, Beani L, Borea A, Antonelli T, Ballati L, Bacciarelli C (1990) Pharmacodynamic profile of isbufylline, a new antibronchospastic xanthine devoid of central excitatory actions. Arzeim Forsch/Drug Res 40:1205-1213
-
(1990)
Arzeim Forsch/Drug Res
, vol.40
, pp. 1205-1213
-
-
Manzini, S.1
Meini, S.2
Giachetti, A.3
Beani, L.4
Borea, A.5
Antonelli, T.6
Ballati, L.7
Bacciarelli, C.8
-
38
-
-
0027420881
-
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at 3-position: Structure-activity relationships at adenosine receptors
-
Muller CE, Shi D, Manning M, Daly JW (1993) Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at 3-position: structure-activity relationships at adenosine receptors. J Med Chem 36:3341-3349
-
(1993)
J Med Chem
, vol.36
, pp. 3341-3349
-
-
Muller, C.E.1
Shi, D.2
Manning, M.3
Daly, J.W.4
-
39
-
-
0000179680
-
1 adenosine receptor mediated modulation of seizure susceptibility
-
Nisticò G, Morselli PL, Lloyd KG, Fariello RG, Engel J (eds) Raven Press, New York
-
1 adenosine receptor mediated modulation of seizure susceptibility. In: Nisticò G, Morselli PL, Lloyd KG, Fariello RG, Engel J (eds) Neurotransmitters, seizures and Epilepsy III. Raven Press, New York, pp 341-353
-
(1986)
Neurotransmitters, Seizures and Epilepsy III
, pp. 341-353
-
-
Murray, T.F.1
Szot, P.2
-
40
-
-
0022415848
-
Purinergic modulation of seizure threshold for pentylentetrazole in the rat
-
Murray TF, Sylvester CS, Schultz CS, Szot P (1985) Purinergic modulation of seizure threshold for pentylentetrazole in the rat. Neuropharmacology 24:761-766
-
(1985)
Neuropharmacology
, vol.24
, pp. 761-766
-
-
Murray, T.F.1
Sylvester, C.S.2
Schultz, C.S.3
Szot, P.4
-
42
-
-
0018945631
-
Aminophylline and theophylline derivatives as antagonists of neuronal depression by adenosine: A microiontophoretic study
-
Perkins MN, Stone TW (1980) Aminophylline and theophylline derivatives as antagonists of neuronal depression by adenosine: a microiontophoretic study. Arch Int Pharmacodyn 246: 205-214
-
(1980)
Arch Int Pharmacodyn
, vol.246
, pp. 205-214
-
-
Perkins, M.N.1
Stone, T.W.2
-
43
-
-
0020319233
-
Universal adenosine receptor antagonism is neither necessary nor desiderable with xanthine antiasthmatics
-
Persson CGA (1982) Universal adenosine receptor antagonism is neither necessary nor desiderable with xanthine antiasthmatics. Med Hypotheses 8:515-526
-
(1982)
Med Hypotheses
, vol.8
, pp. 515-526
-
-
Persson, C.G.A.1
-
44
-
-
0023023143
-
Development of safer xanthine drugs for treatment of obstructive airways disease
-
Persson CGA (1986) Development of safer xanthine drugs for treatment of obstructive airways disease. J Allergy Clin Immun 78: 817-824
-
(1986)
J Allergy Clin Immun
, vol.78
, pp. 817-824
-
-
Persson, C.G.A.1
-
45
-
-
0019971278
-
Seizure activity in animals given enprofylline and theophylline, two xanthines with partly different mechanisms of action
-
Persson CGA, Erjefalt I (1982) Seizure activity in animals given enprofylline and theophylline, two xanthines with partly different mechanisms of action. Arch Int Pharmacodyn 258:267-282
-
(1982)
Arch Int Pharmacodyn
, vol.258
, pp. 267-282
-
-
Persson, C.G.A.1
Erjefalt, I.2
-
46
-
-
0019779853
-
Enprofylline, a principally new antiasthmatic xanthine
-
Persson CGA, Kjellin G (1981) Enprofylline, a principally new antiasthmatic xanthine. Acta Pharmacol Toxicol 49:313-316
-
(1981)
Acta Pharmacol Toxicol
, vol.49
, pp. 313-316
-
-
Persson, C.G.A.1
Kjellin, G.2
-
47
-
-
0020323923
-
Differentiation between bronchodilatation and universal adenosine antagonism among xanthine derivatives
-
Persson CGA, Karlsson JA, Erjefalt I (1982) Differentiation between bronchodilatation and universal adenosine antagonism among xanthine derivatives. Life Sci 30:2181-2189
-
(1982)
Life Sci
, vol.30
, pp. 2181-2189
-
-
Persson, C.G.A.1
Karlsson, J.A.2
Erjefalt, I.3
-
48
-
-
0022552138
-
Non-synaptic modulation of repetitive firing by adenosine is antagonized by 4-aminopyridine in rat hippocampal slice
-
Schubert P, Lee KS (1986) Non-synaptic modulation of repetitive firing by adenosine is antagonized by 4-aminopyridine in rat hippocampal slice. Neurosci Lett 67:334-338
-
(1986)
Neurosci Lett
, vol.67
, pp. 334-338
-
-
Schubert, P.1
Lee, K.S.2
-
49
-
-
0022472326
-
Differential effects of adenosine on pre- and postsynaptic calcium fluxes
-
Schubert P, Heinemann U, Kolb R (1986) Differential effects of adenosine on pre- and postsynaptic calcium fluxes. Brain Res 376:382-386
-
(1986)
Brain Res
, vol.376
, pp. 382-386
-
-
Schubert, P.1
Heinemann, U.2
Kolb, R.3
-
51
-
-
0025373483
-
Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction
-
Sebastiao AM, Ribeiro JA (1990) Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction. Br J Pharmacol 100:55-62
-
(1990)
Br J Pharmacol
, vol.100
, pp. 55-62
-
-
Sebastiao, A.M.1
Ribeiro, J.A.2
-
52
-
-
0023744071
-
Quinolones, theophylline and diclofenac interactions with the γ-aminobutyric acid receptor
-
Segev S, Rehavi M, Rubistein E (1988) Quinolones, theophylline and diclofenac interactions with the γ-aminobutyric acid receptor. Antimicrob Agents Chemother 32:1624-1626
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 1624-1626
-
-
Segev, S.1
Rehavi, M.2
Rubistein, E.3
-
53
-
-
0001441518
-
Adenosine receptors and behavioural actions of methylxanthines
-
Snyder SH, Katims JJ, Annau Z, Bruns RF, Daly JW (1981) Adenosine receptors and behavioural actions of methylxanthines. Proc Natl Acad Sci USA 78:3260-3264
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 3260-3264
-
-
Snyder, S.H.1
Katims, J.J.2
Annau, Z.3
Bruns, R.F.4
Daly, J.W.5
-
54
-
-
0019134056
-
Aminophylline and imidazole as convulsants
-
Stone WE, Javid MJ (1980) Aminophylline and imidazole as convulsants. Arch Int Pharmacodyn 248:120-131
-
(1980)
Arch Int Pharmacodyn
, vol.248
, pp. 120-131
-
-
Stone, W.E.1
Javid, M.J.2
-
55
-
-
0022354475
-
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: Morphological and electroencephalographic correlates
-
Turski WA, Cavalheiro EA, Ikonomidou C, Mello LE. Bortolotto ZA, Turski L (1985) Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates. Brain Res 361:309-323
-
(1985)
Brain Res
, vol.361
, pp. 309-323
-
-
Turski, W.A.1
Cavalheiro, E.A.2
Ikonomidou, C.3
Mello, L.E.4
Bortolotto, Z.A.5
Turski, L.6
-
56
-
-
0022273543
-
Effetcts of enprofylline on A1 and A2 adenosine receptors
-
Ukena D, Schirren CG, Schwabe U (1985) Effetcts of enprofylline on A1 and A2 adenosine receptors. Eur J Pharmacol 117:25-33
-
(1985)
Eur J Pharmacol
, vol.117
, pp. 25-33
-
-
Ukena, D.1
Schirren, C.G.2
Schwabe, U.3
-
57
-
-
0018634064
-
Adenosine regulates via two different types of receptors the accumulation of cyclic AMP in cultured brain cells
-
Van Calker D, Muller M, Hamprecht B (1979) Adenosine regulates via two different types of receptors the accumulation of cyclic AMP in cultured brain cells. J Neurochem 33:999-1005
-
(1979)
J Neurochem
, vol.33
, pp. 999-1005
-
-
Van Calker, D.1
Muller, M.2
Hamprecht, B.3
-
58
-
-
0027332570
-
6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice
-
6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice. Eur J Pharmacol 249:265-270
-
(1993)
Eur J Pharmacol
, vol.249
, pp. 265-270
-
-
Von Lubitz, D.K.J.E.1
Paul, I.A.2
Carter, M.3
Jacobson, K.A.4
|