MKL1 is an epigenetic modulator of TGF-β induced fibrogenesis

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1849, Issue 9, 2015, Pages 1219-1228

  Fan, Zhiwen ^a   Hao, Chenzhi ^a   Li, Min ^a   Dai, Xin ^a   Qin, Hao ^a   Li, Jianfei ^a   Xu, Huihui ^a   Wu, Xiaoyan ^a   Zhang, Liping ^b   Fang, Mingming ^a,c   Zhou, Bisheng ^a   Tian, Wenfang ^a   Xu, Yong ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b XINJIANG MEDICAL UNIVERSITY   (China)

^c Jiangsu Jiankang Vocational Institute   (China)

Author keywords

Epigenetics; Histone methylation; Liver fibrosis; Portal fibroblast; TGF ; Transcriptional regulation

Indexed keywords

HISTONE H3; MEGAKARYOBLASTIC LEUKEMIA 1 PROTEIN; METHYLTRANSFERASE; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MAP3K9 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN BINDING; SMAD3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EPIGENETICS; FIBROBLAST; FIBROGENESIS; GENE EXPRESSION REGULATION; GENE SILENCING; HISTOLOGY; HISTONE METHYLATION; LIVER FIBROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; TRANSACTIVATION; TRANSCRIPTION INITIATION; ANIMAL; BILE DUCT; CELL CULTURE; GENETIC EPIGENESIS; KNOCKOUT MOUSE; LIVER CIRRHOSIS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SURGERY;

MUS;

ANIMALS; BILE DUCTS; CELLS, CULTURED; EPIGENESIS, GENETIC; LIVER CIRRHOSIS; MALE; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; PROTEIN BINDING; RATS; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84939456193     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2015.07.013     Document Type: Article

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