Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin

Genome Biology

Volumn 16, Issue 1, 2015, Pages

  Vandiver, Amy R ^a   Irizarry, Rafael A ^a,b   Hansen, Kasper D ^a   Garza, Luis A ^a   Runarsson, Arni ^a   Li, Xin ^a   Chien, Anna L ^a   Wang, Timothy S ^a   Leung, Sherry G ^a   Kang, Sewon ^a   Feinberg, Andrew P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUNSCREEN;

ADULT; AGE; AGE DISTRIBUTION; AGING; ALGORITHM; ARTICLE; CANCER DIFFERENTIALLY METHYLATED REGION; CAUCASIAN; CLINICAL ARTICLE; COLON CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; CPG ISLAND; DERMIS; DNA METHYLATION; DNA STRUCTURE; EPIDERMIS; FEMALE; GENE EXPRESSION PROFILING; GENE MAPPING; GENE SEQUENCE; GENETIC PARAMETERS; GENOMICS; GENOTYPE; HETEROCHROMATIC DOMAIN; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; HYPOMETHYLATED BLOCK; LONG TERM EXPOSURE; MALE; METHYLATION AGE; MIDDLE AGED; MINFI BLOCK FINDER ALGORITHM; NONMALIGNANT SKIN; NORMAL HUMAN; PHOTOAGING; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN; SQUAMOUS CELL CARCINOMA; STEM CELL REPROGRAMMING DIFFERENTIALLY METHYLATED REGION; SUN EXPOSURE; TISSUE DIFFERENTIALLY METHYLATED REGION; WHOLE GENOME BISULFITE SEQUENCING; ADVERSE EFFECTS; AGED; CUTANEOUS PARAMETERS; DNA SEQUENCE; EPIGENETICS; GENE LIBRARY; GENETIC EPIGENESIS; GENETICS; METABOLISM; PHYSIOLOGY; RADIATION RESPONSE; SKIN NEOPLASMS; SUNLIGHT;

ADULT; AGED; AGING; DNA METHYLATION; EPIDERMIS; EPIGENESIS, GENETIC; EPIGENOMICS; FEMALE; GENE LIBRARY; GENOMICS; HEALTHY VOLUNTEERS; HUMANS; MALE; SEQUENCE ANALYSIS, DNA; SKIN AGING; SKIN NEOPLASMS; SUNLIGHT;

EID: 84939211019     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0644-y     Document Type: Article

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