A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals

Mechanisms of Ageing and Development

Volumn 132, Issue 6-7, 2011, Pages 324-330

  Nebel, Almut ^a   Kleindorp, Rabea ^a   Caliebe, Amke ^a   Nothnagel, Michael ^a   Blanché, Héleàne ^b   Junge, Olaf ^a   Wittig, Michael ^a   Ellinghaus, David ^a   Flachsbart, Friederike ^a   Wichmann, Heinz Erich ^c,d,e   Meitinger, Thomas ^c,f   Nikolaus, Susanna ^a   Franke, Andre ^a   Krawczak, Michael ^a   Lathrop, Mark ^b   Schreiber, Stefan ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b FONDATION JEAN DAUSSET CEPH   (France)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

APOE; GWAS; Longevity

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; ASTROTACTIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EXO1; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ALLELE; APOC1 GENE; APOE GENE; ARTICLE; ASTN1 GENE; AUTOSOME; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GERMAN; GERMANY; HAPLOTYPE; HEREDITY; HUMAN; HUMAN CELL; LONGEVITY; MAJOR GENE; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL;

AGED, 80 AND OVER; ALLELES; APOLIPOPROTEINS E; CASE-CONTROL STUDIES; FEMALE; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GERMANY; HUMANS; LINKAGE DISEQUILIBRIUM; LONGEVITY; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79961208019     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2011.06.008     Document Type: Article

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