Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

Aging Cell

Volumn 10, Issue 4, 2011, Pages 686-698

  Deelen, Joris ^a   Beekman, Marian ^a   Uh, Hae Won ^a   Helmer, Quinta ^a   Kuningas, Maris ^b   Christiansen, Lene ^c,d,e   Kremer, Dennis ^a   van der Breggen, Ruud ^a   Suchiman, H Eka D ^a   Lakenberg, Nico ^a   van den Akker, Erik B ^a,f   Passtoors, Willemijn M ^a   Tiemeier, Henning ^b,g   van Heemst, Diana ^a   de Craen, Anton J ^a   Rivadeneira, Fernando ^b   de Geus, Eco J ^h   Perola, Markus ⁱ   van der Ouderaa, Frans J ^a   Gunn, David A ^j   Boomsma, Dorret I ^h   Uitterlinden, André G ^a,b   Christensen, Kaare ^d,e   van Duijn, Cornelia M ^a,b   Heijmans, Bastiaan T ^a   Houwing Duistermaat, Jeanine J ^a   Westendorp, Rudi G J ^a   Slagboom, P Eline ^a   more..

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d Institute of Public Health Epidemiology   (Denmark)

^e ODENSE UNIVERSITY HOSPITAL   (Denmark)

^f DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^g SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^h VU UNIVERSITY AMSTERDAM   (Netherlands)

ⁱ NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^j UNILEVER RESEARCH   (United Kingdom)

more..

Author keywords

Aging; Apolipoprotein E; Genetics; Genome wide association study; Human; Longevity

Indexed keywords

APOLIPOPROTEIN E; SOMATOMEDIN C;

ADOLESCENT; ADULT; AGED; AGING; ALLELE; ARTICLE; CHROMOSOME 19Q; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; HUMAN; LONGEVITY; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SENESCENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINKAGE DISEQUILIBRIUM; LONGEVITY; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 79960304808     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00705.x     Document Type: Article

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