IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Nakamura, Rei ^a   Sene, Abdoulaye ^a   Santeford, Andrea ^a   Gdoura, Abdelaziz ^a   Kubota, Shunsuke ^a   Zapata, Nicole ^a   Apte, Rajendra S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD163 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 4; STAT3 PROTEIN; 5,15-DIPHENYLPORPHINE; PORPHYRIN; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

AGE; AGING; BLINDNESS; BLOOD SYSTEM DISORDER; CANCER; CELLS AND CELL COMPONENTS; EYE; IMMUNE SYSTEM; INHIBITION; PHENOTYPE; RODENT; SENESCENCE;

ADOPTIVE TRANSFER; AGE RELATED MACULAR DEGENERATION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PHENOTYPE; SENESCENCE; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION; AGED; AGING; ANIMAL; C57BL MOUSE; EYE; IMMUNOLOGY; MACULAR DEGENERATION; MALE; METABOLISM; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); PHYSIOLOGY; RAW 264.7 CELL LINE; VERY ELDERLY;

MUS;

AGED; AGED, 80 AND OVER; AGING; ANIMALS; EYE; FEMALE; HUMANS; INTERLEUKIN-10; MACROPHAGES; MACULAR DEGENERATION; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PORPHYRINS; RAW 264.7 CELLS; RECEPTORS, INTERLEUKIN-10; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84939137853     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8847     Document Type: Article

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