-
1
-
-
0344676389
-
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
-
Ambati J., Anand A., Fernandez S., Sakurai E., Lynn B.C., Kuziel W.A., et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nature Medicine 2003, 9:1390-1397.
-
(2003)
Nature Medicine
, vol.9
, pp. 1390-1397
-
-
Ambati, J.1
Anand, A.2
Fernandez, S.3
Sakurai, E.4
Lynn, B.C.5
Kuziel, W.A.6
-
2
-
-
0019306621
-
Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene
-
Backer J.M., Weinstein I.B. Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene. Science 1980, 209:297-299.
-
(1980)
Science
, vol.209
, pp. 297-299
-
-
Backer, J.M.1
Weinstein, I.B.2
-
3
-
-
34249675425
-
Cigarette smoking and age-related macular degeneration in the EUREYE study
-
Chakravarthy U., Augood C., Bentham G.C., de Jong P.T., Rahu M., Seland J., et al. Cigarette smoking and age-related macular degeneration in the EUREYE study. Ophthalmology 2007, 114:1157-1163.
-
(2007)
Ophthalmology
, vol.114
, pp. 1157-1163
-
-
Chakravarthy, U.1
Augood, C.2
Bentham, G.C.3
de Jong, P.T.4
Rahu, M.5
Seland, J.6
-
4
-
-
16244368037
-
Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study (AREDS) AREDS Report No. 19.
-
Clemons T.E., Milton R.C., Klein R., Seddon J.M., Ferris F.L. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study (AREDS) AREDS Report No. 19. Ophthalmology 2005, 112:533-539.
-
(2005)
Ophthalmology
, vol.112
, pp. 533-539
-
-
Clemons, T.E.1
Milton, R.C.2
Klein, R.3
Seddon, J.M.4
Ferris, F.L.5
-
5
-
-
36749004311
-
Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction
-
Coffey P.J., Gias C., McDermott C.J., Lundh P., Pickering M.C., Sethi C., et al. Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proceedings of the National Academy of Sciences USA 2007, 104:16651-16656.
-
(2007)
Proceedings of the National Academy of Sciences USA
, vol.104
, pp. 16651-16656
-
-
Coffey, P.J.1
Gias, C.2
McDermott, C.J.3
Lundh, P.4
Pickering, M.C.5
Sethi, C.6
-
6
-
-
38749112528
-
Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: Anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model
-
Ding J.D., Lin J., Mace B.E., Herrmann R., Sullivan P., Bowes R.C. Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: Anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model. Vision Research 2008, 48:339-345.
-
(2008)
Vision Research
, vol.48
, pp. 339-345
-
-
Ding, J.D.1
Lin, J.2
Mace, B.E.3
Herrmann, R.4
Sullivan, P.5
Bowes, R.C.6
-
7
-
-
67349093946
-
A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD
-
Fujihara M., Bartels E., Nielsen L.B., Handa J.T. A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD. Experimental Eye Research 2009, 88:1115-1123.
-
(2009)
Experimental Eye Research
, vol.88
, pp. 1115-1123
-
-
Fujihara, M.1
Bartels, E.2
Nielsen, L.B.3
Handa, J.T.4
-
8
-
-
52349098746
-
Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice
-
Fujihara M., Nagai N., Sussan T.E., Biswal S., Handa J.T. Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. PLoS ONE 2008, 3:e3119.
-
(2008)
PLoS ONE
, vol.3
-
-
Fujihara, M.1
Nagai, N.2
Sussan, T.E.3
Biswal, S.4
Handa, J.T.5
-
9
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman G.S., et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proceedings of the National Academy of Sciences USA 2005, 102:7227-7232.
-
(2005)
Proceedings of the National Academy of Sciences USA
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
-
10
-
-
4644293303
-
Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration
-
Hahn P., Qian Y., Dentchev T., Chen L., Beard J., Harris Z.L., et al. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proceedings of the National Academy of Sciences USA 2004, 101:13850-13855.
-
(2004)
Proceedings of the National Academy of Sciences USA
, vol.101
, pp. 13850-13855
-
-
Hahn, P.1
Qian, Y.2
Dentchev, T.3
Chen, L.4
Beard, J.5
Harris, Z.L.6
-
11
-
-
38049086708
-
Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking
-
Hughes A.E., Orr N., Patterson C., Esfandiary H., Hogg R., McConnell V., et al. Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking. PLoS Med 2007, 4:e355.
-
(2007)
PLoS Med
, vol.4
-
-
Hughes, A.E.1
Orr, N.2
Patterson, C.3
Esfandiary, H.4
Hogg, R.5
McConnell, V.6
-
12
-
-
33746628449
-
Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degeneration
-
Imamura Y., Noda S., Hashizume K., Shinoda K., Yamaguchi M., Uchiyama S., et al. Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degeneration. Proceedings of the National Academy of Sciences USA 2006, 103:11282-11287.
-
(2006)
Proceedings of the National Academy of Sciences USA
, vol.103
, pp. 11282-11287
-
-
Imamura, Y.1
Noda, S.2
Hashizume, K.3
Shinoda, K.4
Yamaguchi, M.5
Uchiyama, S.6
-
13
-
-
35748971040
-
SOD2 knockdown mouse model of early AMD
-
Justilien V., Pang J.J., Renganathan K., Zhan X., Crabb J.W., Kim S.R., et al. SOD2 knockdown mouse model of early AMD. Investigative Ophthalmology and Visual Science 2007, 48:4407-4420.
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, pp. 4407-4420
-
-
Justilien, V.1
Pang, J.J.2
Renganathan, K.3
Zhan, X.4
Crabb, J.W.5
Kim, S.R.6
-
14
-
-
20144374260
-
Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: A model for macular degeneration
-
Karan G., Lillo C., Yang Z., Cameron D.J., Locke K.G., Zhao Y., et al. Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: A model for macular degeneration. Proceedings of the National Academy of Sciences USA 2005, 102:4164-4169.
-
(2005)
Proceedings of the National Academy of Sciences USA
, vol.102
, pp. 4164-4169
-
-
Karan, G.1
Lillo, C.2
Yang, Z.3
Cameron, D.J.4
Locke, K.G.5
Zhao, Y.6
-
15
-
-
29744442338
-
Smoking and age related macular degeneration: The number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation
-
Khan J.C., Thurlby D.A., Shahid H., Clayton D.G., Yates J.R., Bradley M., et al. Smoking and age related macular degeneration: The number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. British Journal of Ophthalmology 2006, 90:75-80.
-
(2006)
British Journal of Ophthalmology
, vol.90
, pp. 75-80
-
-
Khan, J.C.1
Thurlby, D.A.2
Shahid, H.3
Clayton, D.G.4
Yates, J.R.5
Bradley, M.6
-
16
-
-
0032518733
-
Relation of smoking to the incidence of age-related maculopathy. The beaver dam eye study
-
Klein R., Klein B.E., Moss S.E. Relation of smoking to the incidence of age-related maculopathy. The beaver dam eye study. American Journal of Epidemiology 1998, 147:103-110.
-
(1998)
American Journal of Epidemiology
, vol.147
, pp. 103-110
-
-
Klein, R.1
Klein, B.E.2
Moss, S.E.3
-
17
-
-
33748325757
-
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
-
Li M., tmaca-Sonmez P., Othman M., Branham K.E., Khanna R., Wade M.S., et al. CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nature Genetics 2006, 38:1049-1054.
-
(2006)
Nature Genetics
, vol.38
, pp. 1049-1054
-
-
Li, M.1
tmaca-Sonmez, P.2
Othman, M.3
Branham, K.E.4
Khanna, R.5
Wade, M.S.6
-
18
-
-
70349567390
-
Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance
-
Maeda T., Maeda A., Matosky M., Okano K., Roos S., Tang J., et al. Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance. Investigative Ophthalmology and Visual Science 2009.
-
(2009)
Investigative Ophthalmology and Visual Science
-
-
Maeda, T.1
Maeda, A.2
Matosky, M.3
Okano, K.4
Roos, S.5
Tang, J.6
-
19
-
-
23844463473
-
Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration
-
Malek G., Johnson L.V., Mace B.E., Saloupis P., Schmechel D.E., Rickman D.W., et al. Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration. Proceedings of the National Academy of Sciences USA 2005, 102:11900-11905.
-
(2005)
Proceedings of the National Academy of Sciences USA
, vol.102
, pp. 11900-11905
-
-
Malek, G.1
Johnson, L.V.2
Mace, B.E.3
Saloupis, P.4
Schmechel, D.E.5
Rickman, D.W.6
-
20
-
-
0036822469
-
Smoking and the 5-year incidence of age-related maculopathy: The Blue Mountains Eye Study
-
Mitchell P., Wang J.J., Smith W., Leeder S.R. Smoking and the 5-year incidence of age-related maculopathy: The Blue Mountains Eye Study. Archives of Ophthalmology 2002, 120:1357-1363.
-
(2002)
Archives of Ophthalmology
, vol.120
, pp. 1357-1363
-
-
Mitchell, P.1
Wang, J.J.2
Smith, W.3
Leeder, S.R.4
-
21
-
-
0036790377
-
Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model
-
Rakoczy P.E., Zhang D., Robertson T., Barnett N.L., Papadimitriou J., Constable I.J., et al. Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model. American Journal of Pathology 2002, 161:1515-1524.
-
(2002)
American Journal of Pathology
, vol.161
, pp. 1515-1524
-
-
Rakoczy, P.E.1
Zhang, D.2
Robertson, T.3
Barnett, N.L.4
Papadimitriou, J.5
Constable, I.J.6
-
22
-
-
33646070308
-
Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration
-
Schmidt S., Hauser M.A., Scott W.K., Postel E.A., Agarwal A., Gallins P., et al. Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. American Journal of Human Genetics 2006, 78:852-864.
-
(2006)
American Journal of Human Genetics
, vol.78
, pp. 852-864
-
-
Schmidt, S.1
Hauser, M.A.2
Scott, W.K.3
Postel, E.A.4
Agarwal, A.5
Gallins, P.6
-
23
-
-
34249719612
-
Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration
-
Scott W.K., Schmidt S., Hauser M.A., Gallins P., Schnetz-Boutaud N., Spencer K.L., et al. Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration. Ophthalmology 2007, 114:1151-1156.
-
(2007)
Ophthalmology
, vol.114
, pp. 1151-1156
-
-
Scott, W.K.1
Schmidt, S.2
Hauser, M.A.3
Gallins, P.4
Schnetz-Boutaud, N.5
Spencer, K.L.6
-
24
-
-
30944437438
-
Smoking and age-related macular degeneration: A review of association
-
Thornton J., Edwards R., Mitchell P., Harrison R.A., Buchan I., Kelly S.P. Smoking and age-related macular degeneration: A review of association. Eye 2005, 19:935-944.
-
(2005)
Eye
, vol.19
, pp. 935-944
-
-
Thornton, J.1
Edwards, R.2
Mitchell, P.3
Harrison, R.A.4
Buchan, I.5
Kelly, S.P.6
-
25
-
-
34648846532
-
Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration
-
Tuo J., Bojanowski C.M., Zhou M., Shen D., Ross R.J., Rosenberg K.I., et al. Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. Investigative Ophthalmology and Visual Science 2007, 48:3827-3836.
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, pp. 3827-3836
-
-
Tuo, J.1
Bojanowski, C.M.2
Zhou, M.3
Shen, D.4
Ross, R.J.5
Rosenberg, K.I.6
-
26
-
-
65449121080
-
Changes in retinal pigment epithelium related to cigarette smoke: Possible relevance to smoking as a risk factor for age-related macular degeneration
-
Wang A.L., Lukas T.J., Yuan M., Du N., Handa J.T., Neufeld A.H. Changes in retinal pigment epithelium related to cigarette smoke: Possible relevance to smoking as a risk factor for age-related macular degeneration. PLoS ONE 2009, 4:e5304.
-
(2009)
PLoS ONE
, vol.4
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Du, N.4
Handa, J.T.5
Neufeld, A.H.6
-
27
-
-
58349109733
-
Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration
-
Wang A.L., Lukas T.J., Yuan M., Du N., Tso M.O., Neufeld A.H. Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration. PLoS ONE 2009, 4:e4160.
-
(2009)
PLoS ONE
, vol.4
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Du, N.4
Tso, M.O.5
Neufeld, A.H.6
|