Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization

Journal of Biological Chemistry

Volumn 289, Issue 12, 2014, Pages 8019-8028

  He, Lizhi ^a   Marneros, Alexander G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; OPHTHALMOLOGY; PATHOLOGY; POLARIZATION;

AGE-RELATED MACULAR DEGENERATION; ANTI-TUMOR ACTIVITIES; CHOROIDAL NEOVASCULARIZATION; DOSE-DEPENDENT MANNER; GLIOBLASTOMA MULTIFORME; NEO-VASCULARIZATION; PATHOLOGIC CONDITIONS; PHARMACOLOGICAL INHIBITORS;

MACROPHAGES;

DOXYCYCLINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL POLARITY; CELL TYPE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBRETINAL NEOVASCULARIZATION;

ANGIOGENESIS; ANTIBIOTICS; INFLAMMATION; INNATE IMMUNITY; MACROPHAGES; MACULAR DEGENERATION; WOUND HEALING;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CHOROIDAL NEOVASCULARIZATION; DINOPROSTONE; DOXYCYCLINE; FEMALE; HUMANS; INTERLEUKIN-13; INTERLEUKIN-1BETA; INTERLEUKIN-4; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL;

EID: 84896999200     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.535765     Document Type: Article

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