Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides

Journal of Medicinal Chemistry

Volumn 58, Issue 15, 2015, Pages 6081-6092

  Barresi, Elisabetta ^a   Bruno, Agostino ^b   Taliani, Sabrina ^a   Cosconati, Sandro ^c   Da Pozzo, Eleonora ^a   Salerno, Silvia ^a   Simorini, Francesca ^a   Daniele, Simona ^a   Giacomelli, Chiara ^a   Marini, Anna Maria ^a   La Motta, Concettina ^a   Marinelli, Luciana ^b   Cosimelli, Barbara ^b   Novellino, Ettore ^b   Greco, Giovanni ^b   Da Settimo, Federico ^a   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYLINDOL 3 YLGLYOXYLAMIDE DERIVATIVE; 2 PHENYLINDOLE DERIVATIVE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR; INDOLE DERIVATIVE; TSPO PROTEIN, HUMAN;

ARTICLE; BINDING SITE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LIPOPHILICITY; MOLECULAR DOCKING; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; METABOLISM; MITOCHONDRIAL MEMBRANE; RAT;

ANIMALS; BINDING SITES; INDOLES; MITOCHONDRIAL MEMBRANES; RATS; RECEPTORS, GABA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84939132265     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00689     Document Type: Article

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