Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11

Oncogene

Volumn 34, Issue 32, 2015, Pages 4211-4218

  Martin, L ^a   Gardner, L B ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD44V ANTIGEN; CYSTINE; GLUTATHIONE; INITIATION FACTOR 2ALPHA; PROTEIN; PROTEIN SLC7A11; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; GLUTAMIC ACID; MESSENGER RNA; SLC7A11 PROTEIN, HUMAN;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CELL STRESS; CONTROLLED STUDY; GENE; GENE CONTROL; GENE EXPRESSION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SLC7A11 GENE; UPREGULATION; ANOXIA; CELL CULTURE; CELL HYPOXIA; GENETICS; HCT116 CELL LINE; HUMAN; IMMUNOBLOTTING; INTRACELLULAR SPACE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA STABILITY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; TUMOR MICROENVIRONMENT;

AMINO ACID TRANSPORT SYSTEM Y+; ANOXIA; BIOLOGICAL TRANSPORT; CELL HYPOXIA; CELL LINE, TUMOR; CELLS, CULTURED; CYSTINE; GLUTAMIC ACID; GLUTATHIONE; HCT116 CELLS; HUMANS; IMMUNOBLOTTING; INTRACELLULAR SPACE; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA STABILITY; RNA, MESSENGER; TUMOR MICROENVIRONMENT; UP-REGULATION;

EID: 84938968380     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.352     Document Type: Article

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