Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection

Antiviral Research

Volumn 122, Issue , 2015, Pages 39-45

  Nelson, Jacob ^a   Roe, Kelsey ^a   Orillo, Beverly ^a   Shi, Pei Yong ^b   Verma, Saguna ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

Author keywords

Adenosine analogue inhibitor; Antiviral; Co treatment; Histone deacetylase inhibitor; Inflammation; West Nile virus

Indexed keywords

ADENOSINE DERIVATIVE; ANTIVIRUS AGENT; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NITD 008; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VORINOSTAT; ADENOSINE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; NITD008; TUMOR NECROSIS FACTOR;

ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; ENCEPHALITIS; FLAVIVIRUS INFECTION; IMMUNOTHERAPY; KIDNEY; MORTALITY; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; SPLEEN; THERAPY EFFECT; TUNEL ASSAY; VERO CELL LINE; VIRUS ENTRY; VIRUS LOAD; VIRUS REPLICATION; WEST NILE VIRUS; ANALOGS AND DERIVATIVES; ANIMAL; CHLOROCEBUS AETHIOPS; COMBINATION DRUG THERAPY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; PATHOLOGY; VIROLOGY; WEST NILE FEVER;

DENGUE VIRUS; FLAVIVIRIDAE; MUS; WEST NILE VIRUS;

ADENOSINE; ANIMALS; BRAIN; CERCOPITHECUS AETHIOPS; CHEMOKINE CCL3; DRUG THERAPY, COMBINATION; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; MICE; TUMOR NECROSIS FACTOR-ALPHA; VERO CELLS; VIRUS REPLICATION; WEST NILE FEVER; WEST NILE VIRUS;

EID: 84938910333     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2015.07.008     Document Type: Article

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