GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury

Experimental Neurology

Volumn 273, Issue , 2015, Pages 11-23

  Almeida Suhett, Camila P ^a   Prager, Eric M ^a   Pidoplichko, Volodymyr ^a   Figueiredo, Taiza H ^a   Marini, Ann M ^a   Li, Zheng ^a,b   Eiden, Lee E ^a,b   Braga, Maria F M ^a  

^a Uniformed Services University of the Health Sciences   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

CA1; Cognitive impairment; Controlled cortical impact; Mild traumatic brain injury; Synaptic transmission

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR BLOCKING AGENT; GLUCOSE TRANSPORTER 1; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; GABAERGIC SYSTEM; HIPPOCAMPAL CA1 REGION; INTERNEURON; LONG TERM POTENTIATION; MALE; NONHUMAN; PASSIVE AVOIDANCE TEST; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRAUMATIC BRAIN INJURY; ANIMAL; AVOIDANCE BEHAVIOR; BRAIN INJURY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ELECTROSTIMULATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MEMORY DISORDERS; METABOLISM; PATHOLOGY; PHYSIOLOGY; REACTION TIME; SPRAGUE DAWLEY RAT; TIME;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; AVOIDANCE LEARNING; BRAIN INJURIES; CA1 REGION, HIPPOCAMPAL; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; GABAERGIC NEURONS; GLUCOSE TRANSPORTER TYPE 1; GLUTAMATE DECARBOXYLASE; INHIBITORY POSTSYNAPTIC POTENTIALS; INTERNEURONS; MALE; MEMORY DISORDERS; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, GABA-A; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TIME FACTORS;

EID: 84938861359     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.07.028     Document Type: Article

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