Neuroprotective efficacy of caramiphen against soman and mechanisms of its action

British Journal of Pharmacology

Volumn 164, Issue 5, 2011, Pages 1495-1505

  Figueiredo, T H ^a   Aroniadou Anderjaska, V ^a   Qashu, F ^a   Apland, J P ^b   Pidoplichko, V ^a   Stevens, D ^a   Ferrara, T M ^b   Braga, M F M ^a  

^a Uniformed Services University of the Health Sciences   (United States)

^b US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

anticonvulsants; caramiphen; GABA A receptors; GABAergic inhibition; nerve agents; neurodegeneration; neuropathology; neuroprotectants; NMDA receptors; soman

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CARAMIPHEN; N METHYL DEXTRO ASPARTIC ACID; SOMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BASOLATERAL AMYGDALA; BEHAVIORAL SEIZURE; BRAIN REGION; BRAIN SLICE; CELL LOSS; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ENTORHINAL CORTEX; HIPPOCAMPUS; IN VITRO STUDY; MALE; NEOCORTEX; NERVE CELL DEGENERATION; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; SEIZURE;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CELL COUNT; CHEMICAL WARFARE AGENTS; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; SOMAN; SYNAPTIC POTENTIALS;

EID: 80054019079     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01427.x     Document Type: Article

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