Positive and negative modulation of the GABA(A) receptor and outcome after traumatic brain injury in rats

Brain Research

Volumn 861, Issue 2, 2000, Pages 325-332

  O'Dell, Dianne M ^a,b   Gibson, Cynthia J ^a   Wilson, Margaret S ^a   DeFord, S Michelle ^a   Hamm, Robert J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bicuculline; Cognition, ( ) aminobutyric acid; Diazepam; Rat; Traumatic brain injury

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE; DIAZEPAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN TEMPERATURE; COGNITION; CONTROLLED STUDY; DRUG EFFECT; GABAERGIC TRANSMISSION; MALE; MAZE TEST; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BICUCULLINE; BRAIN INJURIES; COGNITION; DIAZEPAM; GABA ANTAGONISTS; GABA MODULATORS; MALE; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 0034647086     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02055-2     Document Type: Article

References (54)

1. Baker A.J., Moulton R.J., MacMillan V.H., Shedden P.M. Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. J. Neurosurg. 79:1993;369-372.
2. Bernert H., Turski L. Traumatic brain damage prevented by the non-N-methyl- D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sufamoxylbenzo(f) quinoxaline. Proc. Natl. Acad. Sci. USA. 93:1996;5235-5240.
3. Capruso D.X., Levin H.S. Cognitive impairment following closed head injury. Neurol. Clin. 10:1992;879-893.
4. Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
5. Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
6. Choi D.W., Rothman S. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Ann. Rev. Neurosci. 13:1990;171-182.
7. DeWitt D.S., Hayes R.L., Lyeth B.G., Yuan X.Q., Prough D.S. Effects of traumatic brain injury on cerebral blood flow and metabolism: autoradiographic studies. Anesthesiol. Rev. 15:1988;31-32.
8. Dietrich W.D., Alonso O., Busto R., Globus M.Y.T., Ginsberg M.D. Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat. Acta Neuropathol. 87:1994;250-258.
9. Dixon C.E., Lyeth B.G., Povlishock J.T., Findling R.L., Hamm R.J., Marmarou A., Young H.F., Hayes R.L. A fluid percussion model of experimental brain injury in the rat. J. Neurosurg. 67:1987;110-119.
10. Faden A.I., Demediuk P., Panter S.S., Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science. 244:1989;798-800.
11. Faden A.I., Ivanova S.A., Yakovlev A.G., Mukhin A.G. Neuroprotective effects of group III mGluR in traumatic neuronal injury. J. Neurotrauma. 14:1997;885-895.
12. Foster N.L., VanDerSpeck A.F.L., Aldrich M.S., Berent S., Hichwa R.H., Sackellares J.C., Gilman S., Agranoff B.W. The effect of diazepam sedation on cerebral glucose metabolism in Alzheimer's disease as measured using PET. J. Cereb. Blood Flow Metab. 7:1987;415-420.
13. Gong Q.Z., Delahunty T.M., Hamm R.J., Lyeth B.G. Metabotropic glutamate antagonist, MCPG, treatment of traumatic brain injury in rats. Brain Res. 700:1995;299-302.
14. Hamm R.J., O'Dell D.M., Pike B.R., Lyeth B.G. Cognitive impairment following traumatic brain injury: the effect of pre- and post-injury administration of scopolamine and MK-801. Cognit. Brain Res. 1:1993;1-4.
15. Hayes R.L., Jenkins L.W., Lyeth B.G., Balster R.L., Robinson S.E., Clifton G.L., Stubbins J.F., Young H.F. Pretreatment with phencyclidine, an N-methyl-D-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury. J. Neurotrauma. 5:1988;259-274.
16. Hayes R.L., Jenkins L.W., Lyeth B.G. Neurotransmitter-mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids. J. Neurotrauma. 9:1992;S173-S187.
17. Hovda D.A., Yoshino A., Kawamata T., Katayama Y., Fineman I., Becker D.P. The increase in local cerebral glucose utilization following fluid percussion brain injury is prevented with kynurenic acid and is associated with an increase in calcium. Acta Neurochir. (Suppl.). S1:1990;331-333.
18. Inglefield J.R., Perry J.M., Schwartz R.D. Postischemic inhibition of GABA reuptake by tigabine slows neuronal death in the gerbil hippocampus. Hippocampus. 5:1995;460-468.
19. Jiang J.Y., Lyeth B.G., Kapasi M.Z., Jenkins L.W., Povlishock J.T. Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat. Acta Neuropathol. 84:1992;495-500.
20. Johansen F.F., Diemer N.H. Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta Neurol. Scand. 84:1991;1-6.
21. 2+ conductance in identified leech neurons by benzodiazepines. Proc. Natl. Acad. Sci. USA. 82:1985;3935-3939.
22. Jones T.A., Schallert T. Subcortical deterioration after cortical damage: effects of diazepam and relation to recovery of function. Behav. Brain Res. 51:1992;1-13.
23. Kanthasamy A.G., Matsumoto R.R., Gunasekar P.G., Trunong D.D. Excitoprotective effect of felbamate in cultured cortical neurons. Brain Res. 705:1995;97-104.
24. Katayama Y., Becker D.P., Tamura T., Hovda D.A. Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J. Neurosurg. 73:1990;889-900.
25. Levin H.S., Goldstein F.C., High W.M. Jr., Eisenberg H.M. Disproportionately severe memory deficit in relation to normal intellectual functioning after closed head injury. J. Neurol. Neurosurg. Psychiatry. 51:1988;1294-1301.
26. Loscher W., Schmidt D. Diazepam increases g-aminobutyric acid in human cerebrospinal fluid. J. Neurochem. 49:1987;152-157.
27. Lyden P.D., Lonzo L. Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a g-aminobutyric acid agonist. Stroke. 25:1994;189-196.
28. Lyeth B.G., Jiang J.Y., Liu S. Behavioral protection by moderate hypothermia initiated after experimental traumatic brain injury. J. Neurotrauma. 10:1994;57-64.
29. MacDonald R.L., Kelly K.M. Antiepileptic drug mechanisms of action. Epilepsia. 34:1993;S1-S8.
30. 2+ deregulation, and cytoskeletal pathology. Neurobiol. Aging. 16:1995;187-198.
31. Mathew R.J., Wilson W.H., Daniel D.G. The effect of nonsedating doses of diazepam on regional cerebral blood flow. Biol. Psychiatry. 20:1985;1109-1116.
32. McIntosh T.K., Vink R., Soares H., Hayes R.L., Simon R. Effects of the N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. J. Neurotrauma. 6:1989;247-259.
33. Morris R. Developments of a water maze procedure for studying spatial learning in the rat. J. Neurosci. Methods. 11:1984;47-60.
34. Nilsson P., Hillered L., Ponten U., Ungerstedt U. Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats. J. Cereb. Blood Flow Metab. 10:1990;631-637.
35. Palmer A.M., Marion D.W., Botscheller M.L., Bowen D.M., DeKosky S.T. Increased transmitter amino acid concentration in human ventricular CSF after brain trauma. NeuroReport. 6:1994;153-156.
36. Panter S.S., Faden A.I. Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury. Neurosci. Lett. 136:1992;165-168.
37. Roald O.K., Steen P.A., Milde J.H., Michenfelder J.D. Reversal of the cerebral effects of diazepam in the dog by the benzodiazepine antagonist Ro-15-1788. Acta. Anesthesiol. Scand. 30:1986;341-345.
38. Schallert T., Hernandez T.D., Barth T.M. Recovery of function after brain damage: severe and chronic disruption by diazepam. Brain Res. 379:1986;104-111.
39. Schwartz R.D., Huff R.A., Yu X., Carter M., Bishop M. Post-ischemic diazepam is neuroprotective in the gerbil hippocampus. Brain Res. 647:1994;153-160.
40. Schwartz R.D., Yu X., Katzman M.R., Hayden-Hixon D.M., Perry J.M. Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum. J. Neurosci. 15:1995;529-539.
41. Shuaib A., Mazagri R., Ijaz S. GABA agonist "muscimol" is neuroprotective in repetitive transient forebrain ischemia in gerbils. Exp. Neurol. 123:1993;284-288.
42. Smith D.H., Okiyama K., Thomas M.J., McIntosh T.K. Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. J. Neurosci. 13:1993;5383-5392.
43. Smith D.H., Perri B.R., Raghupathi R., Saatman K.E., McIntosh T.K. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neurosci. Lett. 231:1993;135-138.
44. Sternau L.L., Lust W.D., Ricci A.J., Ratcheson R. Role for gamma-aminobutyric acid in selective vulnerability in gerbils. Stroke. 20:1989;281-287.
45. Study R.E., Barker J.L. Cellular mechanisms of benzodiazepine action. JAMA. 247:1982;2147-2151.
46. Temkin N.R., Dikmen S.S., Winn H.R. Management of head injury. Posttraumatic seizures. Neurosurg. Clin. North Am. 2:1991;425-435.
47. Toulmond S., Serrano A., Benavides J., Scatton B. Prevention by eliprodil (SL 82.0715) of traumatic brain damage in the rat. Existence of a large (18 h) therapeutic window. Brain Res. 620:1993;32-41.
48. Voll C.L., Auer R.N. Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin. Neurology. 41:1991;423-428.
49. Wallis R.A., Panizzon K.L. Felbamate neuroprotection against CA1 traumatic neuronal injury. Eur. J. Pharmacol. 294:1995;475-482.
50. Yamakami I., McIntosh T.K. Alterations in regional cerebral blood flow following brain injury in the rat. J Cereb. Blood Flow Metab. 11:1991;655-660.
51. Ylinen A., Valjakka A., Lahtinen H., Miettinen R., Freund T.F., Riekkinen P. Vigabatrin pre-treatment prevents hilar somatostatin cell loss and the development of interictal spiking activity following sustained stimulation of the perforant path. Neuropeptides. 19:1991;205-211.
52. Yoshino A., Hovda D.A., Kawamata T., Katayama Y., Becker D.P. Dynamic changes in local cerebral glucose utilization following cerebral concussion in rats: evidence of a hyper- and subsequent hypometabolic state. Brain Res. 561:1991;106-119.
53. Young W. Role of calcium in central nervous system injuries. J. Neurotrauma. 9:1992;S9-S25.
54. Yuan X.Q., Prough D.S., Smith T.L., DeWitt D.S. The effect of traumatic brain injury on regional cerebral blood flow in rats. J. Neurotrauma. 5:1988;289-301.