Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

PLoS Genetics

Volumn 11, Issue 7, 2015, Pages

  Evason, Kimberley J ^a,b   Francisco, Macrina T ^a,b   Juric, Vladislava ^b   Balakrishnan, Sanjeev ^b   Lopez Pazmino, Maria del Pilar ^b   Gordan, John D ^a   Kakar, Sanjay ^a   Spitsbergen, Jan ^c   Goga, Andrei ^a,b   Stainier, Didier Y R ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; BETA CATENIN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; AMITRIPTYLINE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HEPATOMEGALY; HUMAN; HUMAN CELL; LARVA; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC ZEBRAFISH; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER NEOPLASMS; METABOLISM; MORTALITY; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; TUMOR CELL LINE; XENOPUS LAEVIS; ZEBRA FISH;

ANIMALIA; DANIO RERIO;

AMITRIPTYLINE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BETA CATENIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; LIVER NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MICE; SEROTONIN UPTAKE INHIBITORS; XENOPUS LAEVIS; ZEBRAFISH;

EID: 84938814942     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005305     Document Type: Article

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