Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Lamb, John R ^a   Zhang, Chunsheng ^a   Xie, Tao ^a   Wang, Kai ^a   Zhang, Bin ^a   Hao, Ke ^a   Chudin, Eugene ^a   Fraser, Hunter B ^a   Millstein, Joshua ^a   Ferguson, Mark ^a   Suver, Christine ^a   Ivanovska, Irena ^a   Scott, Martin ^b   Philippar, Ulrike ^b   Bansal, Dimple ^b   Zhang, Zhan ^a   Burchard, Julja ^a   Smith, Ryan ^a   Greenawalt, Danielle ^a   Cleary, Michele ^b   Derry, Jonathan ^a   Loboda, Andrey ^b   Watters, James ^b   Poon, Ronnie T P ^c   Fan, Sheung T ^c   Yeung, Chun ^c   Lee, Nikki P Y ^c   Guinney, Justin ^d   Molony, Cliona ^a   Emilsson, Valur ^a   Buser Doepner, Carolyn ^b   Zhu, Jun ^a   Friend, Stephen ^b   Mao, Mao ^a   Shaw, Peter M ^b   Dai, Hongyue ^a   Luk, John M ^c   Schadt, Eric E ^a   more..

^a ROSETTA INPHARMATICS   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d SAGE BIONETWORKS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SCATTER FACTOR RECEPTOR;

ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; COPY NUMBER VARIATION; GAIN OF CONNECTIVITY ONCOGENE; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC TRAIT; GENETIC VARIABILITY; HEALTH STATUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CARCINOMA; LOSS OF CONNECTIVITY ONCOGENE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PREDICTION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; ADULT; AGED; ANIMAL; BIOLOGICAL MODEL; CHROMOSOME 1; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENETICS; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; REGRESSION ANALYSIS; TRANSGENIC MOUSE; TUMOR CELL LINE;

ADULT; AGED; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 1; DNA COPY NUMBER VARIATIONS; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-MET; REGRESSION ANALYSIS;

EID: 79960000200     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020090     Document Type: Article

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