Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs

Anti-Cancer Drugs

Volumn 21, Issue 10, 2010, Pages 932-944

  Cordero, Mario David ^a,c   Sánchez Alcázar, José Antonio ^c   Bautista Ferrufino, María Rosa ^a   Carmona López, María Inés ^a   Illanes, Matilde ^a   Ríos, María José ^a   Garrido Maraver, Juan ^c   Alcudia, Ana ^b   Navas, Plácido ^c   Miguela, Manuel De ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

Author keywords

Amitriptyline; Anticancer; Chemotherapeutic drugs; Mitochondrial damage; Oxidation therapy; Oxidative stress; Reactive oxygen species

Indexed keywords

AMITRIPTYLINE; CAMPTOTHECIN; CATALASE; CITRATE SYNTHASE; CYTOCHROME C; DOXORUBICIN; MANGANESE SUPEROXIDE DISMUTASE; METHOTREXATE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL DAMAGE; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TOXICITY; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL;

AMITRIPTYLINE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CARCINOMA, NON-SMALL-CELL LUNG; CYTOTOXINS; DRUG REPOSITIONING; FEMALE; FLOW CYTOMETRY; HELA CELLS; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MICE; MITOCHONDRIA; ORGAN SPECIFICITY; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; UTERINE CERVICAL NEOPLASMS;

EID: 78650067592     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32833ed5f7     Document Type: Article

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