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Volumn 31, Issue 10, 2011, Pages 1494-1504

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma

Author keywords

Biomarker; DKK1; HCC; Prognosis; Wnt

Indexed keywords

ALPHA FETOPROTEIN; DICKKOPF 1 PROTEIN; DICKKOPF 2 PROTEIN; DICKKOPF 3 PROTEIN; DICKKOPF 4 PROTEIN; GLYCOPROTEIN; UNCLASSIFIED DRUG;

EID: 80053997262     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02597.x     Document Type: Article
Times cited : (113)

References (33)
  • 2
    • 33745552897 scopus 로고    scopus 로고
    • Dysregulation of growth factor signaling in human hepatocellular carcinoma
    • Breuhahn K, Longerich T, Schirmacher P. Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 2006; 25: 3787-800.
    • (2006) Oncogene , vol.25 , pp. 3787-3800
    • Breuhahn, K.1    Longerich, T.2    Schirmacher, P.3
  • 3
    • 58149234169 scopus 로고    scopus 로고
    • Molecular therapy for the treatment of hepatocellular carcinoma
    • Greten TF, Korangy F, Manns MP, Malek NP. Molecular therapy for the treatment of hepatocellular carcinoma. Br J Cancer 2009; 100: 19-23.
    • (2009) Br J Cancer , vol.100 , pp. 19-23
    • Greten, T.F.1    Korangy, F.2    Manns, M.P.3    Malek, N.P.4
  • 4
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 1998; 391: 357-62.
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 5
    • 0033516577 scopus 로고    scopus 로고
    • Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling
    • Fedi P, Bafico A, Nieto Soria A, et al. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem 1999; 274: 19465-72.
    • (1999) J Biol Chem , vol.274 , pp. 19465-19472
    • Fedi, P.1    Bafico, A.2    Nieto Soria, A.3
  • 7
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • Mao B, Wu W, Li Y, et al. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 2001; 411: 321-5.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3
  • 8
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 2001; 3: 683-6.
    • (2001) Nat Cell Biol , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 10
    • 34147215025 scopus 로고    scopus 로고
    • Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma
    • Vibhakar R, Foltz G, Yoon JG, et al. Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. Neuro Oncol 2007; 9: 135-44.
    • (2007) Neuro Oncol , vol.9 , pp. 135-144
    • Vibhakar, R.1    Foltz, G.2    Yoon, J.G.3
  • 11
    • 50949117119 scopus 로고    scopus 로고
    • Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis
    • Hall CL, Daignault SD, Shah RB, Pienta KJ, Keller ET. Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis. Prostate 2008; 68: 1396-404.
    • (2008) Prostate , vol.68 , pp. 1396-1404
    • Hall, C.L.1    Daignault, S.D.2    Shah, R.B.3    Pienta, K.J.4    Keller, E.T.5
  • 12
    • 33847224852 scopus 로고    scopus 로고
    • The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types
    • Forget MA, Turcotte S, Beauseigle D, et al. The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types. Br J Cancer 2007; 96: 646-53.
    • (2007) Br J Cancer , vol.96 , pp. 646-653
    • Forget, M.A.1    Turcotte, S.2    Beauseigle, D.3
  • 13
    • 64749106861 scopus 로고    scopus 로고
    • Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas
    • Yu B, Yang X, Xu Y, et al. Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas. J Hepatol 2009; 50: 948-57.
    • (2009) J Hepatol , vol.50 , pp. 948-957
    • Yu, B.1    Yang, X.2    Xu, Y.3
  • 14
    • 70449379992 scopus 로고    scopus 로고
    • The expression and significance of Dickkopf-1 in epithelial ovarian carcinoma
    • Shizhuo W, Tao J, Shulan Z, Bing Z. The expression and significance of Dickkopf-1 in epithelial ovarian carcinoma. Int J Biol Markers 2009; 24: 165-70.
    • (2009) Int J Biol Markers , vol.24 , pp. 165-170
    • Shizhuo, W.1    Tao, J.2    Shulan, Z.3    Bing, Z.4
  • 15
    • 69549111595 scopus 로고    scopus 로고
    • Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer
    • Sheng SL, Huang G, Yu B, Qin WX. Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer. Clin Chem 2009; 55: 1656-64.
    • (2009) Clin Chem , vol.55 , pp. 1656-1664
    • Sheng, S.L.1    Huang, G.2    Yu, B.3    Qin, W.X.4
  • 16
    • 57649158485 scopus 로고    scopus 로고
    • Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment
    • Heider U, Kaiser M, Mieth M, et al. Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment. Eur J Haematol 2009; 82: 31-38.
    • (2009) Eur J Haematol , vol.82 , pp. 31-38
    • Heider, U.1    Kaiser, M.2    Mieth, M.3
  • 17
    • 33747468221 scopus 로고    scopus 로고
    • Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation
    • Politou MC, Heath DJ, Rahemtulla A, et al. Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation. Int J Cancer 2006; 119: 1728-31.
    • (2006) Int J Cancer , vol.119 , pp. 1728-1731
    • Politou, M.C.1    Heath, D.J.2    Rahemtulla, A.3
  • 18
    • 34548828781 scopus 로고    scopus 로고
    • Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma
    • Qian J, Xie J, Hong S, et al. Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma. Blood 2007; 110: 1587-94.
    • (2007) Blood , vol.110 , pp. 1587-1594
    • Qian, J.1    Xie, J.2    Hong, S.3
  • 19
    • 77954374183 scopus 로고    scopus 로고
    • Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy
    • Sato N, Yamabuki T, Takano A, et al. Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy. Cancer Res 2010; 70: 5326-36.
    • (2010) Cancer Res , vol.70 , pp. 5326-5336
    • Sato, N.1    Yamabuki, T.2    Takano, A.3
  • 20
    • 67649213555 scopus 로고    scopus 로고
    • Dickkopf-1 expression as a marker for predicting clinical outcome in esophageal squamous cell carcinoma
    • Makino T, Yamasaki M, Takemasa I, et al. Dickkopf-1 expression as a marker for predicting clinical outcome in esophageal squamous cell carcinoma. Ann Surg Oncol 2009; 16: 2058-64.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2058-2064
    • Makino, T.1    Yamasaki, M.2    Takemasa, I.3
  • 21
    • 34047270776 scopus 로고    scopus 로고
    • Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas
    • Yamabuki T, Takano A, Hayama S, et al. Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Res 2007; 67: 2517-25.
    • (2007) Cancer Res , vol.67 , pp. 2517-2525
    • Yamabuki, T.1    Takano, A.2    Hayama, S.3
  • 22
    • 62449253973 scopus 로고    scopus 로고
    • HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions
    • Tung EK, Wong CM, Yau TO, Lee JM, Ching YP, Ng IO. HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions. Int J Cancer 2009; 124: 1811-9.
    • (2009) Int J Cancer , vol.124 , pp. 1811-1819
    • Tung, E.K.1    Wong, C.M.2    Yau, T.O.3    Lee, J.M.4    Ching, Y.P.5    Ng, I.O.6
  • 23
    • 77954743971 scopus 로고    scopus 로고
    • Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma
    • Lee NP, Tsang FH, Shek FH, et al. Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma. Int J Cancer 2010; 127: 968-76.
    • (2010) Int J Cancer , vol.127 , pp. 968-976
    • Lee, N.P.1    Tsang, F.H.2    Shek, F.H.3
  • 24
    • 66149095045 scopus 로고    scopus 로고
    • Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion
    • Wong CC, Wong CM, Tung EK, Man K, Ng IO. Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion. Hepatology 2009; 49: 1583-94.
    • (2009) Hepatology , vol.49 , pp. 1583-1594
    • Wong, C.C.1    Wong, C.M.2    Tung, E.K.3    Man, K.4    Ng, I.O.5
  • 25
    • 0032850032 scopus 로고    scopus 로고
    • Functional and structural diversity of the human Dickkopf gene family
    • Krupnik VE, Sharp JD, Jiang C, et al. Functional and structural diversity of the human Dickkopf gene family. Gene 1999; 238: 301-13.
    • (1999) Gene , vol.238 , pp. 301-313
    • Krupnik, V.E.1    Sharp, J.D.2    Jiang, C.3
  • 26
    • 4344590372 scopus 로고    scopus 로고
    • Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature
    • Qin LX, Tang ZY. Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature. J Cancer Res Clin Oncol 2004; 130: 497-513.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 497-513
    • Qin, L.X.1    Tang, Z.Y.2
  • 27
    • 33645523023 scopus 로고    scopus 로고
    • Serum tumor markers for detection of hepatocellular carcinoma
    • Zhou L, Liu J, Luo F. Serum tumor markers for detection of hepatocellular carcinoma. World J Gastroenterol 2006; 12: 1175-81.
    • (2006) World J Gastroenterol , vol.12 , pp. 1175-1181
    • Zhou, L.1    Liu, J.2    Luo, F.3
  • 28
    • 68149172533 scopus 로고    scopus 로고
    • Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
    • Ueland T, Otterdal K, Lekva T, et al. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscler Thromb Vasc Biol 2009; 29: 1228-34.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1228-1234
    • Ueland, T.1    Otterdal, K.2    Lekva, T.3
  • 29
    • 77954346513 scopus 로고    scopus 로고
    • Inhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult rats
    • Glaw JT, Skalak TC, Peirce SM. Inhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult rats. Microcirculation 2010; 17: 348-57.
    • (2010) Microcirculation , vol.17 , pp. 348-357
    • Glaw, J.T.1    Skalak, T.C.2    Peirce, S.M.3
  • 30
    • 0033947630 scopus 로고    scopus 로고
    • Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma
    • Tung-Ping Poon R, Fan ST, Wong J. Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. Ann Surg 2000; 232: 10-24.
    • (2000) Ann Surg , vol.232 , pp. 10-24
    • Tung-Ping Poon, R.1    Fan, S.T.2    Wong, J.3
  • 31
    • 63849108139 scopus 로고    scopus 로고
    • Dickkopf-1 enhances migration of HEK293 cell by beta-catenin/E-cadherin degradation
    • Kuang HB, Miao CL, Guo WX, Peng S, Cao YJ, Duan EK. Dickkopf-1 enhances migration of HEK293 cell by beta-catenin/E-cadherin degradation. Front Biosci 2009; 14: 2212-20.
    • (2009) Front Biosci , vol.14 , pp. 2212-2220
    • Kuang, H.B.1    Miao, C.L.2    Guo, W.X.3    Peng, S.4    Cao, Y.J.5    Duan, E.K.6
  • 32
    • 9144240010 scopus 로고    scopus 로고
    • DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway
    • Niida A, Hiroko T, Kasai M, et al. DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene 2004; 23: 8520-6.
    • (2004) Oncogene , vol.23 , pp. 8520-8526
    • Niida, A.1    Hiroko, T.2    Kasai, M.3
  • 33
    • 13944282066 scopus 로고    scopus 로고
    • The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer
    • Gonzalez-Sancho JM, Aguilera O, Garcia JM, et al. The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene 2005; 24: 1098-103.
    • (2005) Oncogene , vol.24 , pp. 1098-1103
    • Gonzalez-Sancho, J.M.1    Aguilera, O.2    Garcia, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.