Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling

Cell Death and Disease

Volumn 6, Issue , 2015, Pages

  Zhang, M ^a   Guo, Y ^a   Fu, H ^a   Hu, S ^a   Pan, J ^a   Wang, Y ^a   Cheng, J ^a   Song, J ^a   Yu, Q ^a   Zhang, S ^a   Xu, J F ^b   Pei, G ^a   Xiang, X ^c   Yang, P ^a   Wang, C Y ^a,b,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; GLUCOSE REGULATED PROTEIN 78; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C JUN; PROTEIN KINASE B; SMAD2 PROTEIN; SMAD3 PROTEIN; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HMGB1 PROTEIN, MOUSE; MAPK1 PROTEIN, MOUSE; STRESS ACTIVATED PROTEIN KINASE; TLR4 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL INFILTRATION; CELL PROTECTION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GENE REPRESSION; HUMAN; HUMAN TISSUE; KIDNEY TUBULE CELL; MOUSE; NONHUMAN; OBSTRUCTION-INDUCED RENAL FIBROSIS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; TRANSCRIPTION INITIATION; URETER OBSTRUCTION; ANIMAL; C57BL MOUSE; DEFICIENCY; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; INTERSTITIAL NEPHRITIS; KIDNEY; KNOCKOUT MOUSE; METABOLISM; NECROSIS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALIA; MUS;

ANIMALS; APOPTOSIS; FIBROSIS; GENE EXPRESSION REGULATION; HMGB1 PROTEIN; HUMANS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NECROSIS; NEPHRITIS, INTERSTITIAL; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR CHOP; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84938772764     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.206     Document Type: Article

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