Loss of dicer exacerbates cyclophosphamide-induced bladder overactivity by enhancing purinergic signaling

American Journal of Pathology

Volumn 181, Issue 3, 2012, Pages 937-946

  Zhang, Shu ^a   Lv, Jian Wei ^b   Yang, Ping ^a,c   Yu, Qilin ^a   Pang, Junfeng ^c   Wang, Zhihua ^a   Guo, Hui ^a   Liu, Shenpei ^a   Hu, Jia ^a   Li, Jiayi ^b   Leng, Jin ^b   Huang, Yiran ^b   Ye, Zhangqun ^a   Wang, Cong Yi ^a,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DICER; MESSENGER RNA; MICRORNA; PURINERGIC P2X RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER BIOPSY; CELL INFILTRATION; CONTROLLED STUDY; DETRUSOR MUSCLE; HUMAN; HUMAN TISSUE; MACROPHAGE; MOUSE; MUSCLE CONTRACTILITY; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN DEFICIENCY; URODYNAMICS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; COMPUTATIONAL BIOLOGY; CYCLOPHOSPHAMIDE; DEAD-BOX RNA HELICASES; GENE DELETION; GENE EXPRESSION REGULATION; GENE TARGETING; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICRORNAS; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PURINERGIC; RIBONUCLEASE III; RNA, MESSENGER; SIGNAL TRANSDUCTION; URINARY BLADDER; URINARY BLADDER, OVERACTIVE;

EID: 84865260656     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.05.035     Document Type: Article

References (43)

1. P.F. Austin, M.L. Ritchey Dysfunctional voiding Pediatr Rev 21 2000 336 341
2. S.L. Schulman Voiding dysfunction in children Urol Clin North Am 31 2004 481 490 ix
3. I. Franco Overactive bladder in children, part 1: pathophysiology J Urol 178 2007 761 768
4. A. Nowara, A. Witek, K. Wilk [Overactive bladder: definition, epidemiology, pathogenesis] Polish Ginekol Pol 78 2007 484 487
5. M.L. Ganz, A.M. Smalarz, T.L. Krupski, J.T. Anger, J.C. Hu, K.U. Wittrup-Jensen, C.L. Pashos Economic costs of overactive bladder in the United States Urology 75 2010 526 532 532.e1-18
6. D.E. Irwin, L. Mungapen, I. Milsom, Z. Kopp, P. Reeves, C. Kelleher The economic impact of overactive bladder syndrome in six Western countries BJU Int 103 2009 202 209
7. P. Abrams, C.J. Kelleher, L.A. Kerr, R.G. Rogers Overactive bladder significantly affects quality of life Am J Manag Care 6 2000 S580 S590
8. D.O. Sussman Overactive bladder: treatment options in primary care medicine J Am Osteopath Assoc 107 2007 379 385
9. L. Jaskiewicz, W. Filipowicz Role of Dicer in posttranscriptional RNA silencing Curr Top Microbiol Immunol 320 2008 77 97
10. S. Albinsson, Y. Suarez, A. Skoura, S. Offermanns, J.M. Miano, W.C. Sessa MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function Arterioscler Thromb Vasc Biol 30 2010 1118 1126
11. S.S. Pullamsetti, C. Doebele, A. Fischer, R. Savai, B. Kojonazarov, B.K. Dahal, H.A. Ghofrani, N. Weissmann, F. Grimminger, A. Bonauer, W. Seeger, A.M. Zeiher, S. Dimmeler, R.T. Schermuly Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension Am J Respir Crit Care Med 185 2012 409 419
12. C. Goettsch, M. Rauner, N. Pacyna, U. Hempel, S.R. Bornstein, L.C. Hofbauer miR-125b Regulates calcification of vascular smooth muscle cells Am J Pathol 179 2011 1594 1600
13. M. Wang, W. Li, G.Q. Chang, C.S. Ye, J.S. Ou, X.X. Li, Y. Liu, T.Y. Cheang, X.L. Huang, S.M. Wang MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities Arterioscler Thromb Vasc Biol 31 2011 2044 2053
14. S. Kuhbandner, S. Brummer, D. Metzger, P. Chambon, F. Hofmann, R. Feil Temporally controlled somatic mutagenesis in smooth muscle Genesis 28 2000 15 22
15. J. Zhong, P. Yang, K. Muta, R. Dong, M. Marrero, F. Gong, C.Y. Wang Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock PLoS One 5 2010 e9593
16. J. Han, J. Zhong, W. Wei, Y. Wang, Y. Huang, P. Yang, S. Purohit, Z. Dong, M.H. Wang, J.X. She, F. Gong, D.M. Stern, C.Y. Wang Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice Diabetes 57 2008 2118 2127
17. X. Rao, J. Zhong, S. Zhang, Y. Zhang, Q. Yu, P. Yang, M.H. Wang, D.J. Fulton, H. Shi, Z. Dong, D. Wang, C.Y. Wang Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury Circulation 123 2011 2964 2974
18. K.E. Andersson, A. Arner Urinary bladder contraction and relaxation: physiology and pathophysiology Physiol Rev 84 2004 935 986
19. C. Fetscher, M. Fleichman, M. Schmidt, S. Krege, M.C. Michel M(3) muscarinic receptors mediate contraction of human urinary bladder Br J Pharmacol 136 2002 641 643
20. M. Matsui, D. Motomura, T. Fujikawa, J. Jiang, S. Takahashi, T. Manabe, M.M. Taketo Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable J Neurosci 22 2002 10627 10632
21. K.E. Andersson LUTS treatment: future treatment options Neurourol Urodyn 26 2007 934 947
22. J.L. Milne Behavioral therapies for overactive bladder: making sense of the evidence J Wound Ostomy Continence Nurs 35 2008 93 101
23. R. Cartwright, I. Afshan, A. Derpapas, G. Vijaya, V. Khullar Novel biomarkers for overactive bladder Nat Rev Urol 8 2011 139 145
24. A.L. Wennberg, D. Altman, C. Lundholm, A. Klint, A. Iliadou, R. Peeker, M. Fall, N.L. Pedersen, I. Milsom Genetic influences are important for most but not all lower urinary tract symptoms: a population-based survey in a cohort of adult Swedish twins Eur Urol 59 2011 1032 1038
25. G. Rohr, J. Kragstrup, D. Gaist, K. Christensen Genetic and environmental influences on urinary incontinence: a Danish population-based twin study of middle-aged and elderly women Acta Obstet Gynecol Scand 83 2004 978 982
26. H.M. Eyres Nervous retention of urine Br Med J 1 1912 484 485
27. H. Lepor Alpha blockers for the treatment of benign prostatic hyperplasia Rev Urol 9 2007 181 190
28. A. Chang, S. Butler, J. Sliwoski, R. Valentino, D. Canning, S. Zderic Social stress in mice induces voiding dysfunction and bladder wall remodeling Am J Physiol Renal Physiol 297 2009 F1101 F1108
29. S.K. Wood, M.A. Baez, S. Bhatnagar, R.J. Valentino Social stress-induced bladder dysfunction: potential role of corticotropin-releasing factor Am J Physiol Regul Integr Comp Physiol 296 2009 R1671 R1678
30. H.J. Litman, W.D. Steers, J.T. Wei, V. Kupelian, C.L. Link, J.B. McKinlay Relationship of lifestyle and clinical factors to lower urinary tract symptoms: results from Boston Area Community Health survey Urology 70 2007 916 921
31. N. Orsini, B. RashidKhani, S.O. Andersson, L. Karlberg, J.E. Johansson, A. Wolk Long-term physical activity and lower urinary tract symptoms in men J Urol 176 2006 2546 2550
32. A.A. Stone, E.S. Mezzacappa, B.A. Donatone, M. Gonder Psychosocial stress and social support are associated with prostate-specific antigen levels in men: results from a community screening program Health Psychol 18 1999 482 486
33. E.C. Suarez, P.G. Saab, M.M. Llabre, C.M. Kuhn, E. Zimmerman Ethnicity, gender, and age effects on adrenoceptors and physiological responses to emotional stress Psychophysiology 41 2004 450 460
34. M.V. Iorio, C. Piovan, C.M. Croce Interplay between microRNAs and the epigenetic machinery: an intricate network Biochim Biophys Acta 1799 2010 694 701
35. F. Sato, S. Tsuchiya, S.J. Meltzer, K. Shimizu MicroRNAs and epigenetics FEBS J 278 2011 1598 1609
36. Q. Wei, K. Bhatt, H.Z. He, Q.S. Mi, V.H. Haase, Z. Dong Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury J Am Soc Nephrol 21 2010 756 761
37. B.A. O'Reilly, A.H. Kosaka, T.K. Chang, A.P. Ford, R. Popert, J.M. Rymer, S.B. McMahon A quantitative analysis of purinoceptor expression in human fetal and adult bladders J Urol 165 2001 1730 1734
38. B.A. O'Reilly, A.H. Kosaka, G.F. Knight, T.K. Chang, A.P. Ford, J.M. Rymer, R. Popert, G. Burnstock, S.B. McMahon P2X receptors and their role in female idiopathic detrusor instability J Urol 167 2002 157 164
39. G.N. Luheshi, M.A. Zar Presence of non-cholinergic motor transmission in human isolated bladder J Pharm Pharmacol 42 1990 223 224
40. S. Palea, W. Artibani, E. Ostardo, D.G. Trist, C. Pietra Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis J Urol 150 1993 2007 2012
41. K. Mulryan, D.P. Gitterman, C.J. Lewis, C. Vial, B.J. Leckie, A.L. Cobb, J.E. Brown, E.C. Conley, G. Buell, C.A. Pritchard, R.J. Evans Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors Nature 403 2000 86 89
42. C. Vial, R.J. Evans P2X receptor expression in mouse urinary bladder and the requirement of P2X(1) receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle Br J Pharmacol 131 2000 1489 1495
43. M. Boudes, P. Uvin, S. Kerselaers, R. Vennekens, T. Voets, D. De Ridder Functional characterization of a chronic cyclophosphamide-induced overactive bladder model in mice Neurourol Urodyn 30 2011 1659 1665