MBD2 regulates TH17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis

Journal of Autoimmunity

Volumn 53, Issue C, 2014, Pages 95-104

  Zhong, Jixin ^a   Yu, Qilin ^a   Yang, Ping ^a   Rao, Xiaoquan ^b   He, Long ^a   Fang, Jing ^a   Tu, Yaqin ^a   Zhang, Zhijun ^a   Lai, Qiaohong ^a   Zhang, Shu ^a   Kuczma, Michal ^b   Kraj, Piatr ^b   Xu, Jun Fa ^c   Gong, Feili ^d   Zhou, Jianfeng ^a   Wen, Li ^e   Eizirik, Decio L ^f   Du, Jie ^g   Wang, Wei ^a   Wang, Cong Yi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^g CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

EAE; Epigenetic; MBD2; Methylation; T bet; TH17

Indexed keywords

GAMMA INTERFERON; H 2.0 LIKE HOMEOBOX PROTEIN; INTERLEUKIN 4; INTERLEUKIN 6; METHYL CPG BINDING PROTEIN 2; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HLX PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MBD2 PROTEIN, MOUSE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEMETHYLATION; DENDRITIC CELL; DNA METHYLATION; EPIGENETICS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; ANIMAL; CHEMICALLY INDUCED; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPIGENESIS, GENETIC; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; T-BOX DOMAIN PROTEINS; TH17 CELLS; TRANSCRIPTION FACTORS;

EID: 84926420518     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2014.05.006     Document Type: Article

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