Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b

Kidney International

Volumn 85, Issue 2, 2014, Pages 352-361

  Wang, Bo ^a   Jha, Jay C ^a   Hagiwara, Shinji ^a   Mcclelland, Aaron D ^a   Jandeleit Dahm, Karin ^a   Thomas, Merlin C ^a   Cooper, Mark E ^a   Kantharidis, Phillip ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

chronic kidney disease; diabetic nephropathy; fibrosis; micro RNAs; TGF beta

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; GROWTH FACTOR RECEPTOR; LET 7B; MICRORNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FIBROGENESIS; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

3' UNTRANSLATED REGIONS; ADENINE; ANIMALS; APOLIPOPROTEINS E; BINDING SITES; CELL LINE; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; KIDNEY; KIDNEY TUBULES; MESANGIAL CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; RENAL INSUFFICIENCY, CHRONIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84895900338     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.372     Document Type: Article

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