Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors

Frontiers in Synaptic Neuroscience

Volumn 7, Issue FEB, 2015, Pages

  Born, Gesche ^a   Grayton, Hannah M ^b,c   Langhorst, Hanna ^a,e   Dudanova, Irina ^a,f   Rohlmann, Astrid ^a   Woodward, Benjamin W ^b   Collier, David A ^b,c   Fernandes, Cathy ^b   Missler, Markus ^a,d  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c ELI LILLY AND COMPANY   (United States)

^d Cells in Motion ^*  (Germany)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

Author keywords

AMPA receptor; Anxiety like behavior; Cognition; Electron microscopy; NMDA receptor; Social interaction; Synaptic plasticity; Vesicle release

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROLIGIN; POSTSYNAPTIC DENSITY PROTEIN 95;

ANIMAL COMMUNICATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GABAERGIC TRANSMISSION; GENE; GENE DELETION; KNOCKOUT MOUSE; MALE; MOUSE; MOUSE MODEL; NEOCORTEX; NERVE CELL PLASTICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; NRXN2 GENE; PATCH CLAMP TECHNIQUE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SYNAPSE;

EID: 84938746932     PISSN: None     EISSN: 16633563     Source Type: Journal    
DOI: 10.3389/fnsyn.2015.00003     Document Type: Article

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