Synaptic computation

Nature

Volumn 431, Issue 7010, 2004, Pages 796-803

  Abbott, L F ^a   Regehr, Wade G ^b  

^a BRANDEIS UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; DATA STORAGE EQUIPMENT; INFORMATION ANALYSIS; LEARNING SYSTEMS; NEUROLOGY; PLASTICITY;

COMPUTATIONAL ENGINES; NEURAL CIRCUITS; SHORT-TERM CHANGES; SYNAPSES;

COMPUTATIONAL METHODS;

BIOLOGY;

BRAIN; CALCULATION; INFORMATION PROCESSING; LEARNING; MEMORY; NERVE CELL PLASTICITY; PRIORITY JOURNAL; REVIEW; SYNAPSE;

ANIMALS; NEURONAL PLASTICITY; NEURONS; SOUND LOCALIZATION; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 7244229524     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03010     Document Type: Review

References (75)

1. Brown, R. E. & Milner, P. M. The legacy of Donald O. Hebb: more than the Hebb synapse. Nature Rev. Neurosci. 4, 1013-1019 (2003).
2. Lynch, M. A. Long-term potentiation and memory. Physiol. Rev. 84, 87-136 (2004).
3. Morris, R. G. Long-term potentiation and memory. Phil. Trans. R. Soc. Lond. B 358, 643-647 (2003).
4. Turrigiano, G. G., Leslie, K. R., Desai, N. S., Rutherford, L. C. & Nelson, S. B. Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature 391, 892-896 (1998).
5. Turrigiano, G. G. & Nelson, S. B. Homeostatic plasticity in the developing nervous system. Nature Rev. Neurosci. 5, 97-107 (2004).
6. Burrone, J. & Murthy, V. N. Synaptic gain control and homeostasis. Curr. Opin. Neurobiol. 13, 560-567 (2003).
7. Zucker, R. S. & Regehr, W. G. Short-term synaptic plasticity. Annu. Rev. Physiol. 64, 355-405 (2002).
8. Eccles, J. C. The Physiology of Synapses (Springer-Verlag, New York, 1964).
9. Katz, B. Nerve, Muscle and Synapse (McGraw Hill, New York, 1966).
10. Kandel, E. K., Schwartz, J. H. & Jessel, T. M. Principles of Neural Science, 1414 (McGraw-Hill/Appleton & Lange, 2000).
11. Trommershauser, J., Schneggenburger, R., Zippelius, A. & Neher, E. Heterogeneous presynaptic release probabilities: functional relevance for short-term plasticity. Biophys. J. 84, 1563-1579 (2003).
12. Reyes, A. et al. Target-cell-specific facilitation and depression in neocortical circuits. Nature Neurosci. 1, 279-285 (1998).
13. Markram, H., Wang, Y. & Tsodyks, M. Differential signaling via the same axon of neocortical pyramidal neurons. Proc. Natl Acad. Sci. USA 95, 5323-5328 (1998).
14. Auger, C. & Marty, A. Quantal currents at single-site central synapses. J. Physiol. 526(1), 3-11 (2000).
15. Magleby, K. L. in Synaptic Function (eds Edelman, G. M., Gall, W. E. & Cowan, W. M.) 21-56 (Wiley, New York, 1987).
16. Freund, T. F., Katona, I. & Piomelli, D. Role of endogenous cannabinoids in synaptic signaling. Physiol. Rev. 83, 1017-1066 (2003).
17. Fitzsimonds, R. M. & Poo, M. M. Retrograde signaling in the development and modification of synapses. Physiol. Rev. 78, 143-170 (1998).
18. Trussell, L. O. & Fischbach, G. D. Glutamate receptor desensitization and its role in synaptic transmission. Neuron 3, 209-218 (1989).
19. Blitz, D. M. & Regehr, W. G. Retinogeniculate synaptic properties controlling spike number and timing in relay neurons. J. Neurophysiol. 90, 2438-2450 (2003).
20. Chen, C., Blitz, D. M. & Regehr, W. G. Contributions of receptor desensitization and saturation to plasticity at the retinogeniculate synapse. Neuron 33, 779-788 (2002).
21. Jones, M. V. & Westbrook, G. L. The impact of receptor desensitization on fast synaptic transmission. Trends Neurosci. 19, 96-101 (1996).
22. Xu-Friedman, M. A. & Regehr, W. G. Ultrastructural contributions to desensitization at cerebellar mossy fiber to granule cell synapses. J. Neurosci. 23, 2182-2192 (2003).
23. Conn, P. J. Physiological roles and therapeutic potential of metabotropic glutamate receptors. Ann. NY Acad. Sci. 1003, 12-21 (2003).
24. Johnston, D. et al. Active dendrites, potassium channels and synaptic plasticity. Phil. Trans. R. Soc. Loud. B 358, 667-674 (2003).
25. Hausser, M., Spruston, N. & Stuart, G. J. Diversity and dynamics of dendritic signaling. Science 290, 739-744 (2000).
26. Craig, A. M. & Boudin, H. Molecular heterogeneity of central synapses: afferent and target regulation. Nature Neurosci. 4, 569-578 (2001).
27. Thomson, A. M., Bannister, A. P., Mercer, A. & Morris, O. T. Target and temporal pattern selection at neocortical synapses. Phil. Trans. R. Soc. Lond. B 357, 1781-1791 (2002).
28. Llano, I., Leresche, N. & Marty, A. Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron 6, 565-574 (1991).
29. Pitler, T. A. & Alger, B. E. Postsynaptic spike firing reduces synaptic GABAA responses in hippocampal pyramidal cells. J. Neurosci. 12, 4122-4132 (1992).
30. Kreitzer, A. C. & Regehr, W. G. Retrograde signaling by endocannabinoids. Curr. Opin. Neurobiol. 12, 324-330 (2002).
31. Wilson, R. I. & Nicoll, R. A. Endocannabinoid signaling in the brain. Science 296, 678-682 (2002).
32. Chavkin, C. Dynorphins are endogenous opioid peptides released from granule cells to act neurohumorly and inhibit excitatory neurotransmission in the hippocampus. Prog. Brain Res. 125, 363-367 (2000).
33. Kombian, S. B., Mouginot, D. & Pittman, Q. J. Dendritically released peptides act as retrograde modulators of afferent excitation in the supraoptic nucleus in vitro. Neuron 19, 903-912 (1997).
34. Tao, H. W. & Poo, M. Retrograde signaling at central synapses. Proc. Natl Acad. Sci. USA 98, 11009-11015 (2001).
35. Wilson, R. I. & Nicoll, R. A. Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature 410, 588-592 (2001).
36. Kreitzer, A. C. & Regehr, W. G. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29, 717-727 (2001).
37. Ohno-Shosaku, T., Maejima, T. & Kano, M. Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron 29, 729-738 (2001).
38. Brenowitz, S. D. & Regehr, W. G. Calcium dependence of retrograde inhibition by endocannabinoids at synapses onto Purkinje cells. J. Neurosci. 23, 6373-6384 (2003).
39. Brown, S. P., Brenowitz, S. D. & Regehr, W. G. Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids. Nature Neurosci. 6, 1048-1057 (2003).
40. Gerdeman, G. L., Ronesi, J. & Lovinger, D. M. Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. Nature Neurosci. 5, 446-451 (2002).
41. Chevaleyre, V. & Castillo, P. E. Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability. Neuron 38, 461-472 (2003).
42. Sjostrom, P. J., Turrigiano, G. G. & Nelson, S. B. Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors. Neuron 39, 641-654 (2003).
43. von der Malsburg, C. & Schneider, W. A neural cocktail-party processor. Biol. Cybern. 54, 29-40 (1986).
44. Sandberg, A., Tegner, J. & Lansner, A. A working memory model based on fast Hebbian learning. Network 14, 789-802 (2003).
45. Schultz, W. & Dickinson, A. Neuronal coding of prediction errors. Annu. Rev. Neurosci. 23, 473-500 (2000).
46. Liaw, J. S. & Berger, T. W. Dynamic synapse: a new concept of neural representation and computation. Hippocampus 6, 591-600 (1996).
47. Okatan, M. & Grossberg, S. Frequency-dependent synaptic potentiation, depression and spike timing induced by Hebbian pairing in cortical pyramidal neurons. Neural Netw. 13, 699-708 (2000).
48. Dittman, J. S., Kreitzer, A. C. & Regehr, W. G. Interplay between facilitation, depression, and residual calcium at three presynaptic terminals. J. Neurosci. 20, 1374-1385 (2000).
49. Fuhrmann, G., Segev, I., Markram, H. & Tsodyks, M. Coding of temporal information by activity-dependent synapses. J. Neurophysiol 87, 140-148 (2002).
50. Silberberg, G., Wu, C. & Markram, H. Synaptic dynamics control the timing of neuronal excitation in the activated neocortical microcircuit. J. Physiol. 556, 19-27 (2004).
51. Markram, H., Gupta, A., Uziel, A., Wang, Y. & Tsodyks, M. Information processing with frequency-dependent synaptic connections. Neurobiol. Learn. Mem. 70, 101-112 (1998).
52. Abbott, L. F., Varela, J. A., Sen, K. & Nelson, S. B. Synaptic depression and cortical gain control. Science 275, 220-224 (1997).
53. Hopfield, J. J. & Brody, C. D. Learning rules and network repair in spike-timing-based computation networks. Proc. Natl Acad. Sci. USA 101, 337-342 (2004).
54. Markram, H., Pikus, D., Gupta, A. & Tsodyks, M. Potential for multiple mechanisms, phenomena and algorithms for synaptic plasticity at single synapses. Neuropharmacology 37, 489-500 (1998).
55. Melamed, O., Gerstner, W., Maass, W., Tsodyks, M. & Markram, H. Coding and learning of behavioral sequences. Trends Neurosci. 27, 11-4; discussion 14-5 (2004).
56. Maass, W. & Markram, H. Synapses as dynamic memory buffers. Neural Netw. 15, 155-161 (2002).
57. Fortune, E. S. & Rose, G. J. Roles for short-term synaptic plasticity in behavior. J. Physiol. Paris96, 539-545 (2002).
58. O'Donovan, M. J. & Rinzel, J. Synaptic depression: a dynamic regulator of synaptic communication with varied functional roles. Trends Neurosci. 20, 431-433 (1997).
59. Goldman, M. S., Maldonado, P. & Abbott, L. F. Redundancy reduction and sustained firing with stochastic depressing synapses. J. Neurosci. 22, 584-591 (2002).
60. Lisman, J. E. Bursts as a unit of neural information: making unreliable synapses reliable. Trends Neurosci. 20, 38-43 (1997).
61. Thomson, A. M. Presynaptic frequency- and pattern-dependent filtering. J. Comput. Neurosci. 15, 159-202 (2003).
62. Tsodyks, M. V. & Markram, H. The neural code between neocortical pyramidal neurons depends on neurotransmitter release probability. Proc. Natl Acad. Sci. USA 94, 719-723 (1997).
63. Brenowitz, S., David, J. & Trussell, L. Enhancement of synaptic efficacy by presynaptic GABA(B) receptors. Neuron 20, 135-141 (1998).
64. Trussell, L. O., Zhang, S. & Raman, I. M. Desensitization of AMPA receptors upon multiquantal neurotransmitter release. Neuron 10, 1185-1196 (1993).
65. Brenowitz, S. & Trussell, L. O. Minimizing synaptic depression by control of release probability. J. Neurosci. 21, 1857-1867 (2001).
66. Chance, F. S., Nelson, S. B. & Abbott, L. F. Synaptic depression and the temporal response characteristics of VI cells. J. Neurosci. 18, 4785-4799 (1998).
67. Carandini, M., Heeger, D. J. & Senn, W. A synaptic explanation of suppression in visual cortex. J. Neurosci. 22, 10053-10065 (2002).
68. Freeman, T. C., Durand, S., Kiper, D. C. & Carandini, M. Suppression without inhibition in visual cortex. Neuron 35, 759-771 (2002).
69. Maass, W. & Zador, A. M. Dynamic stochastic synapses as computational units. Neural Comput. 11, 903-917 (1999).
70. Zador, A. M. & Dobrunz, L. E. Dynamic synapses in the cortex. Neuron 19, 1-4 (1997).
71. Kuba, H., Koyano, K. & Ohmori, H. Synaptic depression improves coincidence detection in the nucleus laminaris in brainstem slices of the chick embryo. Eur. J. Neurosci. 15, 984-990 (2002).
72. Cook, D. L., Schwindt, P. C., Grande, L. A. & Spain, W. J. Synaptic depression in the localization of sound. Nature 421, 66-70 (2003).
73. Konishi, M. Coding of auditory space. Annu. Rev. Neurosci. 26, 31-55 (2003).
74. Grossberg, S. in Brain and Information: Event Related Potentials (eds Karrer, R., Cohen, J. & Tueting, P.) 58-142 (New York Academy of Science, New York, 1994).
75. Chung, S., Li, X. & Nelson, S. B. Short-term depression at thalamocortical synapses contributes to rapid adaptation of cortical sensory responses in vivo. Neuron 34, 437-446 (2002).