메뉴 건너뛰기




Volumn 22, Issue 12, 2014, Pages 2570-2578

Metabolomic profiles and childhood obesity

Author keywords

androgen; branched chain amino acids; DHEA S; insulin resistance; metabolomics; obesity; steroid hormones; untargeted

Indexed keywords

ADIPONECTIN; ANDROGEN; BRANCHED CHAIN AMINO ACID; C REACTIVE PROTEIN; GLUCOSE; INTERLEUKIN 6; LEPTIN; TRIACYLGLYCEROL; GLYCOSYLATED HEMOGLOBIN;

EID: 84938728779     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20901     Document Type: Article
Times cited : (136)

References (38)
  • 1
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • Newgard CB, An J, Bain JR, et al., A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 2009; 9: 311-326.
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3
  • 2
    • 33646475134 scopus 로고    scopus 로고
    • Probing gender-specific metabolism differences in humans by nuclear magnetic resonance-based metabonomics
    • Kochhar S, Jacobs DM, Ramadan Z, Berruex F, Fuerholz A, Fay LB,. Probing gender-specific metabolism differences in humans by nuclear magnetic resonance-based metabonomics. Anal Biochem 2006; 352: 274-281.
    • (2006) Anal Biochem , vol.352 , pp. 274-281
    • Kochhar, S.1    Jacobs, D.M.2    Ramadan, Z.3    Berruex, F.4    Fuerholz, A.5    Fay, L.B.6
  • 3
    • 77956094483 scopus 로고    scopus 로고
    • Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity
    • Mihalik SJ, Goodpaster BH, Kelley DE, et al., Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity. Obesity 2010; 18: 1695-1700.
    • (2010) Obesity , vol.18 , pp. 1695-1700
    • Mihalik, S.J.1    Goodpaster, B.H.2    Kelley, D.E.3
  • 4
    • 80053921608 scopus 로고    scopus 로고
    • Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes
    • Oberbach A, Bluher M, Wirth H, et al., Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes. J Proteome Res 2011; 10: 4769-4788.
    • (2011) J Proteome Res , vol.10 , pp. 4769-4788
    • Oberbach, A.1    Bluher, M.2    Wirth, H.3
  • 5
    • 77949267650 scopus 로고    scopus 로고
    • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
    • Tai ES, Tan ML, Stevens RD, et al., Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. Diabetologia 2010; 53: 757-767.
    • (2010) Diabetologia , vol.53 , pp. 757-767
    • Tai, E.S.1    Tan, M.L.2    Stevens, R.D.3
  • 6
    • 69549097700 scopus 로고    scopus 로고
    • Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
    • Huffman KM, Shah SH, Stevens RD, et al., Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care 2009; 32: 1678-1683.
    • (2009) Diabetes Care , vol.32 , pp. 1678-1683
    • Huffman, K.M.1    Shah, S.H.2    Stevens, R.D.3
  • 7
    • 79953737332 scopus 로고    scopus 로고
    • Metabolite profiles and the risk of developing diabetes
    • Wang TJ, Larson MG, Vasan RS, et al., Metabolite profiles and the risk of developing diabetes. Nat Med 2011; 17: 448-453.
    • (2011) Nat Med , vol.17 , pp. 448-453
    • Wang, T.J.1    Larson, M.G.2    Vasan, R.S.3
  • 8
    • 84874800752 scopus 로고    scopus 로고
    • Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents
    • McCormack SE, Shaham O, McCarthy MA, et al., Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatr Obes 2013; 8: 52-61.
    • (2013) Pediatr Obes , vol.8 , pp. 52-61
    • McCormack, S.E.1    Shaham, O.2    McCarthy, M.A.3
  • 9
    • 84859073302 scopus 로고    scopus 로고
    • Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: Evidence for enhanced mitochondrial oxidation
    • Mihalik SJ, Michaliszyn SF, de las Heras J, et al., Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation. Diabetes Care 2012; 35: 605-611.
    • (2012) Diabetes Care , vol.35 , pp. 605-611
    • Mihalik, S.J.1    Michaliszyn, S.F.2    De Las Heras, J.3
  • 10
    • 84868628375 scopus 로고    scopus 로고
    • Metabolomic profiling of amino acids and beta-cell function relative to insulin sensitivity in youth
    • Michaliszyn SF, Sjaarda LA, Mihalik SJ, et al., Metabolomic profiling of amino acids and beta-cell function relative to insulin sensitivity in youth. J Clin Endocrinol Metab 2012; 97: E2119-E2124.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E2119-E2124
    • Michaliszyn, S.F.1    Sjaarda, L.A.2    Mihalik, S.J.3
  • 11
    • 84867900785 scopus 로고    scopus 로고
    • Childhood obesity is associated with changes in the serum metabolite profile
    • Wahl S, Yu Z, Kleber M, et al., Childhood obesity is associated with changes in the serum metabolite profile. Obes Facts 2012; 5: 660-670.
    • (2012) Obes Facts , vol.5 , pp. 660-670
    • Wahl, S.1    Yu, Z.2    Kleber, M.3
  • 12
    • 77952951283 scopus 로고    scopus 로고
    • Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: A study in Zucker diabetic fatty rats
    • Lenaers E, De Feyter HM, Hoeks J, et al., Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats. Obesity 2010; 18: 1100-1107.
    • (2010) Obesity , vol.18 , pp. 1100-1107
    • Lenaers, E.1    De Feyter, H.M.2    Hoeks, J.3
  • 14
    • 84966677516 scopus 로고    scopus 로고
    • 2012 World Health Organization Accessed 5/21
    • World Health Organization. BMI Classification. Global Database on Body Mass Index [ http://www.apps.who.int/bmi/index.jsp?introPage=intro-3.html ]. Accessed 5/21, 2012.
    • BMI Classification. Global Database on Body Mass Index
  • 15
    • 78751503250 scopus 로고    scopus 로고
    • The National Academies Collection: Reports funded by National Institutes of Health
    • Institute of Medicine National Research Council Committee to Reexamine I. O. M. Pregnancy Weight Guidelines. Rasmussen K.M. Yaktine A.L. eds. Washington (DC): National Academies Press (US) National Academy of Sciences.
    • Institute of Medicine National Research Council Committee to Reexamine I. O. M. Pregnancy Weight Guidelines. The National Academies Collection: Reports funded by National Institutes of Health. In:, Rasmussen KM, Yaktine AL, eds. Weight Gain During Pregnancy: Reexamining the Guidelines. Washington (DC): National Academies Press (US) National Academy of Sciences; 2009.
    • (2009) Weight Gain during Pregnancy: Reexamining the Guidelines
  • 19
    • 2642531190 scopus 로고    scopus 로고
    • A nearly continuous measure of birth weight for gestational age using a United States national reference
    • Oken E, Kleinman KP, Rich-Edwards J, Gillman MW,. A nearly continuous measure of birth weight for gestational age using a United States national reference. BMC Pediatr 2003; 3: 6.
    • (2003) BMC Pediatr , vol.3 , pp. 6
    • Oken, E.1    Kleinman, K.P.2    Rich-Edwards, J.3    Gillman, M.W.4
  • 20
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen HN,. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 1990; 70: 43-77.
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 21
    • 84927529795 scopus 로고    scopus 로고
    • Visceral adipose tissue measured by DXA correlates with measurement by CT and is associated with cardiometabolic risk factors in children
    • doi:10/111/ijpo.249.
    • Bosch TA, Dengel DR, Kelly AS, Sinaiko AR, Moran A, Steinberger J,. Visceral adipose tissue measured by DXA correlates with measurement by CT and is associated with cardiometabolic risk factors in children. Pediatr Obes 2014. doi:10/111/ijpo.249.
    • (2014) Pediatr Obes
    • Bosch, T.A.1    Dengel, D.R.2    Kelly, A.S.3    Sinaiko, A.R.4    Moran, A.5    Steinberger, J.6
  • 22
    • 84878622190 scopus 로고    scopus 로고
    • Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
    • Lackey DE, Lynch CJ, Olson KC, et al., Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity. Am J Physiol 2013; 304: E1175-E1187.
    • (2013) Am J Physiol , vol.304 , pp. E1175-E1187
    • Lackey, D.E.1    Lynch, C.J.2    Olson, K.C.3
  • 23
    • 84883478660 scopus 로고    scopus 로고
    • Gut microbiota from twins discordant for obesity modulate metabolism in mice
    • Ridaura VK, Faith JJ, Rey FE, et al., Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341: 1241214.
    • (2013) Science , vol.341 , pp. 1241214
    • Ridaura, V.K.1    Faith, J.J.2    Rey, F.E.3
  • 24
    • 78751535748 scopus 로고    scopus 로고
    • Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model
    • Sishi B, Loos B, Ellis B, Smith W, du Toit EF, Engelbrecht AM,. Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model. Exp Physiol 2011; 96: 179-193.
    • (2011) Exp Physiol , vol.96 , pp. 179-193
    • Sishi, B.1    Loos, B.2    Ellis, B.3    Smith, W.4    Du Toit, E.F.5    Engelbrecht, A.M.6
  • 25
    • 84860439210 scopus 로고    scopus 로고
    • Interplay between lipids and branched-chain amino acids in development of insulin resistance
    • Newgard CB,. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab 2012; 15: 606-614.
    • (2012) Cell Metab , vol.15 , pp. 606-614
    • Newgard, C.B.1
  • 26
    • 49449083937 scopus 로고    scopus 로고
    • Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
    • Shaham O, Wei R, Wang TJ, et al., Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity. Mol Syst Biol 2008; 4: 214.
    • (2008) Mol Syst Biol , vol.4 , pp. 214
    • Shaham, O.1    Wei, R.2    Wang, T.J.3
  • 27
    • 78650732495 scopus 로고    scopus 로고
    • Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women
    • Fiehn O, Garvey WT, Newman JW, Lok KH, Hoppel CL, Adams SH,. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS One 2010; 5: e15234.
    • (2010) PloS One , vol.5 , pp. e15234
    • Fiehn, O.1    Garvey, W.T.2    Newman, J.W.3    Lok, K.H.4    Hoppel, C.L.5    Adams, S.H.6
  • 28
    • 84862282554 scopus 로고    scopus 로고
    • Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state
    • Adams SH,. Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. Adv Nutr 2011; 2: 445-456.
    • (2011) Adv Nutr , vol.2 , pp. 445-456
    • Adams, S.H.1
  • 29
    • 34547569051 scopus 로고    scopus 로고
    • Obesity, inflammation, and vascular disease: The role of the adipose tissue as an endocrine organ
    • Calabro P, Yeh ET,. Obesity, inflammation, and vascular disease: the role of the adipose tissue as an endocrine organ. Subcell Biochem 2007; 42: 63-91.
    • (2007) Subcell Biochem , vol.42 , pp. 63-91
    • Calabro, P.1    Yeh, E.T.2
  • 31
    • 0037303916 scopus 로고    scopus 로고
    • Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes
    • Roh C, Han J, Tzatsos A, Kandror KV,. Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes. Am J Physiol 2003; 284: E322-E330.
    • (2003) Am J Physiol , vol.284 , pp. E322-E330
    • Roh, C.1    Han, J.2    Tzatsos, A.3    Kandror, K.V.4
  • 32
    • 79960188174 scopus 로고    scopus 로고
    • Premature adrenarche: Novel lessons from early onset androgen excess
    • Idkowiak J, Lavery GG, Dhir V, et al., Premature adrenarche: novel lessons from early onset androgen excess. Eur J Endocrinol 2011; 165: 189-207.
    • (2011) Eur J Endocrinol , vol.165 , pp. 189-207
    • Idkowiak, J.1    Lavery, G.G.2    Dhir, V.3
  • 33
    • 0036920767 scopus 로고    scopus 로고
    • Insulin sensitivity and the insulin-like growth factor system in prepubertal boys with premature adrenarche
    • Denburg MR, Silfen ME, Manibo AM, et al., Insulin sensitivity and the insulin-like growth factor system in prepubertal boys with premature adrenarche. J Clin Endocrinol Metab 2002; 87: 5604-5609.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5604-5609
    • Denburg, M.R.1    Silfen, M.E.2    Manibo, A.M.3
  • 35
    • 84862076724 scopus 로고    scopus 로고
    • GH activity and markers of inflammation: A crossover study in healthy volunteers treated with GH and a GH receptor antagonist
    • Andreassen M, Frystyk J, Faber J, Kristensen LO,. GH activity and markers of inflammation: a crossover study in healthy volunteers treated with GH and a GH receptor antagonist. Eur J Endocrinol 2012; 166: 811-819.
    • (2012) Eur J Endocrinol , vol.166 , pp. 811-819
    • Andreassen, M.1    Frystyk, J.2    Faber, J.3    Kristensen, L.O.4
  • 36
    • 0031827641 scopus 로고    scopus 로고
    • Hyperinsulinaemia, dyslipaemia and cardiovascular risk in girls with a history of premature pubarche
    • Ibanez L, Potau N, Chacon P, Pascual C, Carrascosa A,. Hyperinsulinaemia, dyslipaemia and cardiovascular risk in girls with a history of premature pubarche. Diabetologia 1998; 41: 1057-1063.
    • (1998) Diabetologia , vol.41 , pp. 1057-1063
    • Ibanez, L.1    Potau, N.2    Chacon, P.3    Pascual, C.4    Carrascosa, A.5
  • 37
    • 0034503112 scopus 로고    scopus 로고
    • Premature adrenarche - Normal variant or forerunner of adult disease?
    • Ibanez L, Dimartino-Nardi J, Potau N, Saenger P,. Premature adrenarche-normal variant or forerunner of adult disease? Endocr Rev 2000; 21: 671-696.
    • (2000) Endocr Rev , vol.21 , pp. 671-696
    • Ibanez, L.1    Dimartino-Nardi, J.2    Potau, N.3    Saenger, P.4
  • 38
    • 69349095304 scopus 로고    scopus 로고
    • A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome
    • Cox J, Williams S, Grove K, Lane RH, Aagaard-Tillery KM,. A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. Am J Obstet Gynecol 2009; 201: 281.e281-281.e289.
    • (2009) Am J Obstet Gynecol , vol.201 , pp. 281e281-281e289
    • Cox, J.1    Williams, S.2    Grove, K.3    Lane, R.H.4    Aagaard-Tillery, K.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.