Adaptations in Mitochondrial Function Parallel, but Fail to Rescue, the Transition to Severe Hyperglycemia and Hyperinsulinemia: A Study in Zucker Diabetic Fatty Rats

Obesity

Volumn 18, Issue 6, 2010, Pages 1100-1107

  Lenaers, Ellen ^a,b   De Feyter, Henk M ^c   Hoeks, Joris ^a,b   Schrauwen, Patrick ^a,b   Schaart, Gert ^a,b   Nabben, Miranda ^a,b   Nicolay, Klaas ^c   Prompers, Jeanine J ^c   Hesselink, Matthijs K C ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CARNITINE; GLUCOSE; GLUTAMIC ACID; INSULIN; PALMITOYL COENZYME A; PYRUVIC ACID; UNCOUPLING PROTEIN 3; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 3;

ADAPTATION; AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FATTY ACID OXIDATION; FOOD INTAKE; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSURIA; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MUSCLE CELL; MUSCLE FIBER TYPE IIB; MUSCLE MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; RAT; RESPIROMETRY; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; HOSPITALIZATION; HYPERINSULINISM; METABOLISM; OBESITY; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN CARBONYLATION; SKELETAL MUSCLE; ZUCKER RAT; COMPLICATION; SEVERITY OF ILLNESS INDEX;

ADAPTATION, PHYSIOLOGICAL; ADENINE NUCLEOTIDE TRANSLOCATOR 1; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; HYPERGLYCEMIA; HYPERINSULINISM; ION CHANNELS; MALE; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE FIBERS, SKELETAL; OBESITY; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PROTEIN CARBONYLATION; RATS; RATS, ZUCKER; SEVERITY OF ILLNESS INDEX;

RATTUS;

EID: 77952951283     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2009.372     Document Type: Article

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