메뉴 건너뛰기




Volumn 7, Issue 5, 2014, Pages 545-557

Siltuximab for multicentric Castleman disease

Author keywords

Castleman disease; IL 6; monoclonal antibody; siltuximab; targeted therapy

Indexed keywords

INTERLEUKIN 6; SILTUXIMAB; ANTINEOPLASTIC AGENT; C REACTIVE PROTEIN; INTERLEUKIN 6 RECEPTOR; MONOCLONAL ANTIBODY;

EID: 84907056599     PISSN: 17474086     EISSN: 17474094     Source Type: Journal    
DOI: 10.1586/17474086.2014.946402     Document Type: Article
Times cited : (16)

References (73)
  • 1
    • 84858708447 scopus 로고    scopus 로고
    • Surgery in Castleman's disease. A systematic review of 404 published cases
    • Talat N, Belgaumkar AP, Schulte KM. Surgery in Castleman's disease. a systematic review of 404 published cases. Ann Surg 2012;255(4):677-84
    • (2012) Ann Surg , vol.255 , Issue.4 , pp. 677-684
    • Talat, N.1    Belgaumkar, A.P.2    Schulte, K.M.3
  • 2
    • 84867907569 scopus 로고    scopus 로고
    • The clinical spectrum of Castleman's disease
    • Dispenzieri A, Armitage JO, Loe MJ, et al. The clinical spectrum of Castleman's disease. Am J Hematol 2012;87(11): 997-1002
    • (2012) Am J Hematol , vol.87 , Issue.11 , pp. 997-1002
    • Dispenzieri, A.1    Armitage, J.O.2    Loe, M.J.3
  • 3
    • 80053189058 scopus 로고    scopus 로고
    • Castleman's disease: Systematic analysis of 416 patients from the literature
    • Talat N, Schulte KM. Castleman's disease: systematic analysis of 416 patients from the literature. Oncologist 2011;16(9):1316-24
    • (2011) Oncologist , vol.16 , Issue.9 , pp. 1316-1324
    • Talat, N.1    Schulte, K.M.2
  • 4
    • 79955556128 scopus 로고    scopus 로고
    • Castleman's disease: From basic mechanisms to molecular therapeutics
    • El-Osta HE, Kurzrock R. Castleman's disease: from basic mechanisms to molecular therapeutics. Oncologist 2011;16(4): 497-511
    • (2011) Oncologist , vol.16 , Issue.4 , pp. 497-511
    • El-Osta, H.E.1    Kurzrock, R.2
  • 5
    • 77956108220 scopus 로고    scopus 로고
    • Castleman disease in the 21st century: An update on diagnosis, assessment, and therapy
    • van Rhee F, Stone K, Szmania S, et al. Castleman disease in the 21st century: an update on diagnosis, assessment, and therapy. Clin Adv Hematol Oncol 2010; 8(7):486-98
    • (2010) Clin Adv Hematol Oncol , vol.8 , Issue.7 , pp. 486-498
    • Van Rhee, F.1    Stone, K.2    Szmania, S.3
  • 7
    • 17144417319 scopus 로고    scopus 로고
    • The aetiology and management of Castleman disease at 50 years: Translating pathophysiology to patient care
    • Casper C. The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol 2005;129(1):3-17
    • (2005) Br J Haematol , vol.129 , Issue.1 , pp. 3-17
    • Casper, C.1
  • 8
    • 84907048971 scopus 로고    scopus 로고
    • Use of a claims database to characterize and estimate the incidence of Castleman's disease
    • Mehra M, Cossrow N, Stellhorn RA, et al. Use of a claims database to characterize and estimate the incidence of Castleman's disease. Blood (ASH Annual Meeting Abstracts) 2012;120:abstract 4253
    • (2012) Blood (ASH Annual Meeting Abstracts) , pp. 120
    • Mehra, M.1    Cossrow, N.2    Stellhorn, R.A.3
  • 9
    • 63549095091 scopus 로고    scopus 로고
    • The role of immune suppression and HHV8 in the increasing incidence of HIV-associated multicentric Castleman's disease
    • Powles T, Stebbing J, Bazeos A, et al. The role of immune suppression and HHV8 in the increasing incidence of HIV-associated multicentric Castleman's disease. Ann Oncol 2009;20(4):775-9
    • (2009) Ann Oncol , vol.20 , Issue.4 , pp. 775-779
    • Powles, T.1    Stebbing, J.2    Bazeos, A.3
  • 10
    • 84896054346 scopus 로고    scopus 로고
    • Clinical epidemiology and treatment patterns of patients with multicentric Castleman disease: Results from two US treatment centres
    • Robinson D Jr, Reynolds M, Casper C, et al. Clinical epidemiology and treatment patterns of patients with multicentric Castleman disease: results from two US treatment centres. Br J Haematol 2014; 165(1):39-48
    • (2014) Br J Haematol , vol.165 , Issue.1 , pp. 39-48
    • Robinson, D.1    Reynolds, M.2    Casper, C.3
  • 11
    • 0034651687 scopus 로고    scopus 로고
    • HHV8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV8-positive plasmablastic lymphoma
    • Dupin N, Diss TL, Kellam P, et al. HHV8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV8-positive plasmablastic lymphoma. Blood 2000;95(4):1406-12
    • (2000) Blood , vol.95 , Issue.4 , pp. 1406-1412
    • Dupin, N.1    Diss, T.L.2    Kellam, P.3
  • 12
    • 0035313167 scopus 로고    scopus 로고
    • Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders
    • Du MQ, Liu H, Diss TC, et al. Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders. Blood 2001;97(7):2130-6
    • (2001) Blood , vol.97 , Issue.7 , pp. 2130-2136
    • Du, M.Q.1    Liu, H.2    Diss, T.C.3
  • 14
    • 80052358980 scopus 로고    scopus 로고
    • Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
    • Jones SA, Scheller J, Rose-John S. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J Clin Invest 2011;121(9):3375-83
    • (2011) J Clin Invest , vol.121 , Issue.9 , pp. 3375-3383
    • Jones, S.A.1    Scheller, J.2    Rose-John, S.3
  • 16
    • 77953980528 scopus 로고    scopus 로고
    • IL-6: From its discovery to clinical applications
    • Kishimoto T. IL-6: from its discovery to clinical applications. Int Immunol 2010; 22(5):347-52
    • (2010) Int Immunol , vol.22 , Issue.5 , pp. 347-352
    • Kishimoto, T.1
  • 17
    • 35648995976 scopus 로고    scopus 로고
    • Interleukin-6 and its receptor in cancer: Implications for translational therapeutics
    • Hong DS, Angelo LS, Kurzrock R. Interleukin-6 and its receptor in cancer: implications for translational therapeutics. Cancer 2007;110(9):1911-28
    • (2007) Cancer , vol.110 , Issue.9 , pp. 1911-1928
    • Hong, D.S.1    Angelo, L.S.2    Kurzrock, R.3
  • 18
    • 77956262040 scopus 로고    scopus 로고
    • Castleman's disease - A two compartment model of HHV8 infection
    • Schulte KM, Talat N. Castleman's disease - a two compartment model of HHV8 infection. Nat Rev Clin Oncol 2010;7(9):533-43
    • (2010) Nat Rev Clin Oncol , vol.7 , Issue.9 , pp. 533-543
    • Schulte, K.M.1    Talat, N.2
  • 19
    • 0024459013 scopus 로고
    • Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease
    • Yoshizaki K, Matsuda T, Nishimoto N, et al. Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood 1989;74(4):1360-7
    • (1989) Blood , vol.74 , Issue.4 , pp. 1360-1367
    • Yoshizaki, K.1    Matsuda, T.2    Nishimoto, N.3
  • 20
    • 0025183151 scopus 로고
    • Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice
    • Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest 1990;86(2):592-9
    • (1990) J Clin Invest , vol.86 , Issue.2 , pp. 592-599
    • Brandt, S.J.1    Bodine, D.M.2    Dunbar, C.E.3    Nienhuis, A.W.4
  • 21
    • 0036915034 scopus 로고    scopus 로고
    • Anti-interleukin 6 (IL-6) receptor antibody suppresses Castleman's disease like symptoms emerged in IL-6 transgenic mice
    • Katsume A, Saito H, Yamada Y, et al. Anti-interleukin 6 (IL-6) receptor antibody suppresses Castleman's disease like symptoms emerged in IL-6 transgenic mice. Cytokine 2002;20(6):304-11
    • (2002) Cytokine , vol.20 , Issue.6 , pp. 304-311
    • Katsume, A.1    Saito, H.2    Yamada, Y.3
  • 22
    • 0029166033 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
    • Soulier J, Grollet L, Oksenhendler E, et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 1995;86(4):1276-80
    • (1995) Blood , vol.86 , Issue.4 , pp. 1276-1280
    • Soulier, J.1    Grollet, L.2    Oksenhendler, E.3
  • 23
    • 0034782082 scopus 로고    scopus 로고
    • HHV8 infection status of AIDS-unrelated and AIDS-associated multicentric Castleman's disease
    • Suda T, Katano H, Delsol G, et al. HHV8 infection status of AIDS-unrelated and AIDS-associated multicentric Castleman's disease. Pathol Int 2001;51(9): 671-9
    • (2001) Pathol Int , vol.51 , Issue.9 , pp. 671-679
    • Suda, T.1    Katano, H.2    Delsol, G.3
  • 24
    • 65349181345 scopus 로고    scopus 로고
    • Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor
    • Adam N, Rabe B, Suthaus J, et al. Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor. J Virol 2009;83(10): 5117-26
    • (2009) J Virol , vol.83 , Issue.10 , pp. 5117-5126
    • Adam, N.1    Rabe, B.2    Suthaus, J.3
  • 25
    • 84861851475 scopus 로고    scopus 로고
    • HHV8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice
    • Suthaus J, Stuhlmann-Laeisz C, Tompkins VS, et al. HHV8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice. Blood 2012;119(22): 5173-81
    • (2012) Blood , vol.119 , Issue.22 , pp. 5173-5181
    • Suthaus, J.1    Stuhlmann-Laeisz, C.2    Tompkins, V.S.3
  • 26
    • 79960514270 scopus 로고    scopus 로고
    • Plasma HHV8 DNA predicts relapse in individuals with HIV-associated multicentric Castleman disease
    • Stebbing J, Adams C, Sanitt A, et al. Plasma HHV8 DNA predicts relapse in individuals with HIV-associated multicentric Castleman disease. Blood 2011;118(2): 271-5
    • (2011) Blood , vol.118 , Issue.2 , pp. 271-275
    • Stebbing, J.1    Adams, C.2    Sanitt, A.3
  • 27
    • 0034665781 scopus 로고    scopus 로고
    • High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric Castleman disease in HIV-infected patients
    • Oksenhendler E, Carcelain G, Aoki Y, et al. High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric Castleman disease in HIV-infected patients. Blood 2000;96(6):2069-73
    • (2000) Blood , vol.96 , Issue.6 , pp. 2069-2073
    • Oksenhendler, E.1    Carcelain, G.2    Aoki, Y.3
  • 28
    • 84891096530 scopus 로고    scopus 로고
    • Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
    • Polizzotto MN, Uldrick TS, Wang V, et al. Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease. Blood 2013;122(26): 4189-98
    • (2013) Blood , vol.122 , Issue.26 , pp. 4189-4198
    • Polizzotto, M.N.1    Uldrick, T.S.2    Wang, V.3
  • 29
    • 84874775510 scopus 로고    scopus 로고
    • Human herpesvirus 8-related Castleman disease in the absence of HIV infection
    • Dossier A, Meignin V, Fieschi C, et al. Human herpesvirus 8-related Castleman disease in the absence of HIV infection. Clin Infect Dis 2013;56(6):833-42
    • (2013) Clin Infect Dis , vol.56 , Issue.6 , pp. 833-842
    • Dossier, A.1    Meignin, V.2    Fieschi, C.3
  • 30
    • 84900445271 scopus 로고    scopus 로고
    • HHV8-negative, idiopathic multicentric Castleman disease: Novel insights into biology, pathogenesis, and therapy
    • Fajgenbaum DC, van Rhee F, Nabel CS. HHV8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy. Blood 2014;123(19):2924-33
    • (2014) Blood , vol.123 , Issue.19 , pp. 2924-2933
    • Fajgenbaum, D.C.1    Van Rhee, F.2    Nabel, C.S.3
  • 31
    • 0035425457 scopus 로고    scopus 로고
    • Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy
    • Chronowski GM, Ha CS, Wilder RB, et al. Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy. Cancer 2001;92(3):670-6
    • (2001) Cancer , vol.92 , Issue.3 , pp. 670-676
    • Chronowski, G.M.1    Ha, C.S.2    Wilder, R.B.3
  • 32
    • 38449113389 scopus 로고    scopus 로고
    • Brief communication: Rituximab in HIV-associated multicentric Castleman disease
    • Bower M, Powles T, Williams S, et al. Brief communication: rituximab in HIV-associated multicentric Castleman disease. Ann Intern Med 2007;147(12): 836-9
    • (2007) Ann Intern Med , vol.147 , Issue.12 , pp. 836-839
    • Bower, M.1    Powles, T.2    Williams, S.3
  • 33
    • 34548232784 scopus 로고    scopus 로고
    • Prospective study of rituximab in chemotherapy-dependent human immunodeficiency virus associated multicentric Castleman's disease: ANRS 117 CastlemaB Trial
    • Gérard L, Bérezné A, Galicier L, et al. Prospective study of rituximab in chemotherapy-dependent human immunodeficiency virus associated multicentric Castleman's disease: ANRS 117 CastlemaB Trial. J Clin Oncol 2007; 25(22):3350-6
    • (2007) J Clin Oncol , vol.25 , Issue.22 , pp. 3350-3356
    • Gérard, L.1    Bérezné, A.2    Galicier, L.3
  • 34
    • 79959300575 scopus 로고    scopus 로고
    • Clinical features and outcome in HIV-associated multicentric Castleman's disease
    • Bower M, Newsom-Davis T, Naresh K, et al. Clinical features and outcome in HIV-associated multicentric Castleman's disease. J Clin Oncol 2011;29(18):2481-6
    • (2011) J Clin Oncol , vol.29 , Issue.18 , pp. 2481-2486
    • Bower, M.1    Newsom-Davis, T.2    Naresh, K.3
  • 35
    • 80053221406 scopus 로고    scopus 로고
    • Improved outcome with rituximab in patients with HIV-associated multicentric Castleman disease
    • Hoffmann C, Schmid H, Müller M, et al. Improved outcome with rituximab in patients with HIV-associated multicentric Castleman disease. Blood 2011;118(13): 3499-503
    • (2011) Blood , vol.118 , Issue.13 , pp. 3499-3503
    • Hoffmann, C.1    Schmid, H.2    Müller, M.3
  • 36
    • 84858067317 scopus 로고    scopus 로고
    • Rituximab decreases the risk of lymphoma in patients with HIV-associated multicentric Castleman disease
    • Gérard L, Michot JM, Burcheri S, et al. Rituximab decreases the risk of lymphoma in patients with HIV-associated multicentric Castleman disease. Blood 2012;119(10): 2228-33
    • (2012) Blood , vol.119 , Issue.10 , pp. 2228-2233
    • Gérard, L.1    Michot, J.M.2    Burcheri, S.3
  • 37
    • 52249122417 scopus 로고    scopus 로고
    • Rituximab failure in fulminant multicentric HIV/human herpesvirus 8-associated Castleman's disease with multiorgan failure: Report of two cases
    • Buchler T, Dubash S, Lee V, et al. Rituximab failure in fulminant multicentric HIV/human herpesvirus 8-associated Castleman's disease with multiorgan failure: report of two cases. AIDS 2008;22(13): 1685-7
    • (2008) AIDS , vol.22 , Issue.13 , pp. 1685-1687
    • Buchler, T.1    Dubash, S.2    Lee, V.3
  • 38
    • 78649480343 scopus 로고    scopus 로고
    • How i treat HIV-associated multicentric Castleman disease
    • Bower M. How I treat HIV-associated multicentric Castleman disease. Blood 2010; 116(22):4415-21
    • (2010) Blood , vol.116 , Issue.22 , pp. 4415-4421
    • Bower, M.1
  • 39
    • 67849111384 scopus 로고    scopus 로고
    • HIV-associated multicentric Castleman disease
    • Oksenhendler E. HIV-associated multicentric Castleman disease. Curr Opin HIV AIDS 2009;4(1):16-21
    • (2009) Curr Opin HIV AIDS , vol.4 , Issue.1 , pp. 16-21
    • Oksenhendler, E.1
  • 40
    • 79959858676 scopus 로고    scopus 로고
    • High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: A pilot study of virus-activated cytotoxic therapy
    • Uldrick TS, Polizzotto MN, Aleman K, et al. High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy. Blood 2011;117(26):6977-86
    • (2011) Blood , vol.117 , Issue.26 , pp. 6977-6986
    • Uldrick, T.S.1    Polizzotto, M.N.2    Aleman, K.3
  • 41
    • 0033959608 scopus 로고    scopus 로고
    • Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy
    • Nishimoto N, Sasai M, Shima Y, et al. Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. Blood 2000;95(1):56-61
    • (2000) Blood , vol.95 , Issue.1 , pp. 56-61
    • Nishimoto, N.1    Sasai, M.2    Shima, Y.3
  • 42
    • 27144488346 scopus 로고    scopus 로고
    • Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
    • Nishimoto N, Kanakura Y, Aozasa K, et al. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005;106(8): 2627-32
    • (2005) Blood , vol.106 , Issue.8 , pp. 2627-2632
    • Nishimoto, N.1    Kanakura, Y.2    Aozasa, K.3
  • 43
    • 33645090196 scopus 로고    scopus 로고
    • Long-term remission in HIV-negative patients with multicentric Castleman's disease using rituximab
    • Ide M, Kawachi Y, Izumi Y, et al. Long-term remission in HIV-negative patients with multicentric Castleman's disease using rituximab. Eur J Haematol 2006;76(2):119-23
    • (2006) Eur J Haematol , vol.76 , Issue.2 , pp. 119-123
    • Ide, M.1    Kawachi, Y.2    Izumi, Y.3
  • 44
    • 0347519172 scopus 로고    scopus 로고
    • A case of multicentric Castleman's disease associated with advanced systemic amyloidosis treated with chemotherapy and anti-CD20 monoclonal antibody
    • Gholam D, Vantelon JM, Al-Jijakli A, Bourhis JH. A case of multicentric Castleman's disease associated with advanced systemic amyloidosis treated with chemotherapy and anti-CD20 monoclonal antibody. Ann Hematol 2003;82(12):766-8
    • (2003) Ann Hematol , vol.82 , Issue.12 , pp. 766-768
    • Gholam, D.1    Vantelon, J.M.2    Al-Jijakli, A.3    Bourhis, J.H.4
  • 45
    • 16344388769 scopus 로고    scopus 로고
    • Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena
    • Ocio EM, Sanchez-Guijo FM, Diez-Campelo M, et al. Efficacy of rituximab in an aggressive form of multicentric Castleman disease associated with immune phenomena. Am J Hematol 2005;78(4):302-5
    • (2005) Am J Hematol , vol.78 , Issue.4 , pp. 302-305
    • Ocio, E.M.1    Sanchez-Guijo, F.M.2    Diez-Campelo, M.3
  • 46
    • 84892448928 scopus 로고    scopus 로고
    • Short-term efficacy of the IL6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease: Report of two cases
    • Nagao A, Nakazawa S, Hanabusa H. Short-term efficacy of the IL6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease: report of two cases. J Hematol Oncol 2014;7(1):10
    • (2014) J Hematol Oncol , vol.7 , Issue.1 , pp. 10
    • Nagao, A.1    Nakazawa, S.2    Hanabusa, H.3
  • 47
    • 33746543554 scopus 로고    scopus 로고
    • Effects of bortezomib on pro-inflammatory cytokine levels and transfusion dependency in a patient with multicentric Castleman disease
    • Hess G, Wagner V, Kreft A, et al. Effects of bortezomib on pro-inflammatory cytokine levels and transfusion dependency in a patient with multicentric Castleman disease. Br J Haematol 2006;134(5):544-5
    • (2006) Br J Haematol , vol.134 , Issue.5 , pp. 544-545
    • Hess, G.1    Wagner, V.2    Kreft, A.3
  • 48
    • 74049107864 scopus 로고    scopus 로고
    • Efficacy of bortezomib in refractory form of multicentric Castleman disease associated to poems syndrome (MCDPOEMS variant)
    • Sobas MA, Alonso Vence N, Diaz Arias J, et al. Efficacy of bortezomib in refractory form of multicentric Castleman disease associated to poems syndrome (MCDPOEMS variant). Ann Hematol 2010;89(2): 217-19
    • (2010) Ann Hematol , vol.89 , Issue.2 , pp. 217-219
    • Sobas, M.A.1    Alonso Vence, N.2    Diaz Arias, J.3
  • 49
    • 77953441380 scopus 로고    scopus 로고
    • Successful treatment of Castleman's disease with interleukin-1 receptor antagonist (Anakinra)
    • El-Osta H, Janku F, Kurzrock R. Successful treatment of Castleman's disease with interleukin-1 receptor antagonist (Anakinra). Mol Cancer Ther 2010;9(6):1485-8
    • (2010) Mol Cancer Ther , vol.9 , Issue.6 , pp. 1485-1488
    • El-Osta, H.1    Janku, F.2    Kurzrock, R.3
  • 50
    • 59149104498 scopus 로고    scopus 로고
    • IL-1RA agonist (anakinra) in the treatment of multifocal Castleman disease: Case report
    • Galeotti C, Tran TA, Franchi-Abella S, et al. IL-1RA agonist (anakinra) in the treatment of multifocal Castleman disease: case report. J Pediatr Hematol Oncol 2008; 30(12):920-4
    • (2008) J Pediatr Hematol Oncol , vol.30 , Issue.12 , pp. 920-924
    • Galeotti, C.1    Tran, T.A.2    Franchi-Abella, S.3
  • 51
    • 0025990893 scopus 로고
    • Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia
    • Klein B, Wijdenes J, Zhang XG, et al. Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 1991;78(5):1198-204
    • (1991) Blood , vol.78 , Issue.5 , pp. 1198-1204
    • Klein, B.1    Wijdenes, J.2    Zhang, X.G.3
  • 52
    • 0028013066 scopus 로고
    • Brief report: Alleviation of systemic manifestations of Castleman's disease by monoclonal anti-interleukin-6 antibody
    • Beck JT, Hsu SM, Wijdenes J, et al. Brief report: alleviation of systemic manifestations of Castleman's disease by monoclonal anti-interleukin-6 antibody. N Engl J Med 1994;330(9):602-5
    • (1994) N Engl J Med , vol.330 , Issue.9 , pp. 602-605
    • Beck, J.T.1    Hsu, S.M.2    Wijdenes, J.3
  • 53
    • 0028885888 scopus 로고
    • Measurement of whole body interleukin-6 (IL-6) production: Prediction of the efficacy of anti-IL-6 treatments
    • Lu ZY, Brailly H, Wijdenes J, et al. Measurement of whole body interleukin-6 (IL-6) production: prediction of the efficacy of anti-IL-6 treatments. Blood 1995;86(8): 3123-31
    • (1995) Blood , vol.86 , Issue.8 , pp. 3123-3131
    • Lu, Z.Y.1    Brailly, H.2    Wijdenes, J.3
  • 54
    • 0142250392 scopus 로고    scopus 로고
    • Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
    • Trikha M, Corringham R, Klein B, Rossi JF. Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003;9(13):4653-65
    • (2003) Clin Cancer Res , vol.9 , Issue.13 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 55
    • 0031811798 scopus 로고    scopus 로고
    • Chimaeric anti-interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: A phase i dose-escalating study
    • van Zaanen HC, Lokhorst HM, Aarden LA, et al. Chimaeric anti-interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: a phase I dose-escalating study. Br J Haematol 1998; 102(3):783-90
    • (1998) Br J Haematol , vol.102 , Issue.3 , pp. 783-790
    • Van Zaanen, H.C.1    Lokhorst, H.M.2    Aarden, L.A.3
  • 56
    • 0029780037 scopus 로고    scopus 로고
    • Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feedback loop
    • van Zaanen HC, Koopmans RP, Aarden LA, et al. Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feedback loop. J Clin Invest 1996;98(6):1441-8
    • (1996) J Clin Invest , vol.98 , Issue.6 , pp. 1441-1448
    • Van Zaanen, H.C.1    Koopmans, R.P.2    Aarden, L.A.3
  • 57
    • 84907051810 scopus 로고    scopus 로고
    • Janssen Biotech, Inc; Horsham, PA, USA [Last accessed 8 July 2014]
    • Sylvant. SylvantTM (siltuximab) for injection [package insert]. Janssen Biotech, Inc; Horsham, PA, USA: 2014. Available from: www. sylvant. com [Last accessed 8 July 2014]
    • (2014) Sylvant TM (Siltuximab) for Injection [Package Insert]
  • 58
    • 84879849025 scopus 로고    scopus 로고
    • A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease
    • Kurzrock R, Voorhees PM, Casper C, et al. A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease. Clin Cancer Res 2013; 19(13):3659-70
    • (2013) Clin Cancer Res , vol.19 , Issue.13 , pp. 3659-3670
    • Kurzrock, R.1    Voorhees, P.M.2    Casper, C.3
  • 59
    • 78149324897 scopus 로고    scopus 로고
    • Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease
    • Song SN, Tomosugi N, Kawabata H, et al. Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease. Blood 2010; 116(18):3627-34
    • (2010) Blood , vol.116 , Issue.18 , pp. 3627-3634
    • Song, S.N.1    Tomosugi, N.2    Kawabata, H.3
  • 60
    • 50349085287 scopus 로고    scopus 로고
    • Involvement of hepcidin in the anemia of multiple myeloma
    • Sharma S, Nemeth E, Chen YH, et al. Involvement of hepcidin in the anemia of multiple myeloma. Clin Cancer Res 2008; 14(11):3262-7
    • (2008) Clin Cancer Res , vol.14 , Issue.11 , pp. 3262-3267
    • Sharma, S.1    Nemeth, E.2    Chen, Y.H.3
  • 61
    • 77957283115 scopus 로고    scopus 로고
    • Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease
    • van Rhee F, Fayad L, Voorhees P, et al. Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease. J Clin Oncol 2010; 28(23):3701-8
    • (2010) J Clin Oncol , vol.28 , Issue.23 , pp. 3701-3708
    • Van Rhee, F.1    Fayad, L.2    Voorhees, P.3
  • 62
    • 84905005470 scopus 로고    scopus 로고
    • Siltuximab for multicentric Castleman's disease: A randomized, double-blind, placebo-controlled trial
    • july 17 [Epub ahead of print]
    • van Rhee F, Wong RS, Munshi N, et al. Siltuximab for multicentric Castleman's disease: a randomized, double-blind, placebo-controlled trial. Lancet Oncol. 2014 july 17. pii: S1470-2045(14)70319-5. doi: 10. 1016/S1470-2045(14)70319-5. [Epub ahead of print]
    • (2014) Lancet Oncol.
    • Van Rhee, F.1    Wong, R.S.2    Munshi, N.3
  • 63
    • 84903879405 scopus 로고    scopus 로고
    • Siltuximab: First global approval
    • Markham A, Patel T. Siltuximab: first global approval. Drugs 2014;74:1147-52
    • (2014) Drugs , vol.74 , pp. 1147-1152
    • Markham, A.1    Patel, T.2
  • 64
    • 84907056897 scopus 로고    scopus 로고
    • Siltuximab reverses muscle wasting in patients with multicentric Castleman's disease
    • Kirk M, Kurzrock R, van Rhee F, et al. Siltuximab reverses muscle wasting in patients with multicentric Castleman's disease. Blood (ASH Annual Meeting Abstracts) 2013;122(21):abstract 4394
    • (2013) Blood (ASH Annual Meeting Abstracts) , vol.122 , Issue.21
    • Kirk, M.1    Kurzrock, R.2    Van Rhee, F.3
  • 65
    • 84903603962 scopus 로고    scopus 로고
    • An open-label, phase 2, multicenter study of the safety of long-term treatment with siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman's disease
    • van Rhee F, Casper C, Voorhees PM, et al. An open-label, phase 2, multicenter study of the safety of long-term treatment with siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman's disease. Blood (ASH Annual Meeting Abstracts) 2013;122(21):abstract 1806
    • (2013) Blood (ASH Annual Meeting Abstracts) , vol.122 , Issue.21
    • Van Rhee, F.1    Casper, C.2    Voorhees, P.M.3
  • 66
    • 84892792932 scopus 로고    scopus 로고
    • Evaluation of the QTc prolongation potential of a monoclonal antibody, siltuximab, in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, or low-volume multiple myeloma
    • Thomas SK, Suvorov A, Noens L, et al. Evaluation of the QTc prolongation potential of a monoclonal antibody, siltuximab, in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, or low-volume multiple myeloma. Cancer Chemother Pharmacol 2014;73(1):35-42
    • (2014) Cancer Chemother Pharmacol , vol.73 , Issue.1 , pp. 35-42
    • Thomas, S.K.1    Suvorov, A.2    Noens, L.3
  • 67
    • 84865462806 scopus 로고    scopus 로고
    • Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: Multicentric Castleman disease (KSHVMCD) and the KSHV inflammatory cytokine syndrome
    • Polizzotto MN, Uldrick TS, Hu D, Yarchoan R. Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHVMCD) and the KSHV inflammatory cytokine syndrome. Front Microbiol 2012;3:73
    • (2012) Front Microbiol , vol.3 , pp. 73
    • Polizzotto, M.N.1    Uldrick, T.S.2    Hu, D.3    Yarchoan, R.4
  • 68
    • 84865523451 scopus 로고    scopus 로고
    • Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
    • Uldrick TS, Polizzotto MN, Yarchoan R. Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease. Curr Opin Oncol 2012; 24(5):495-505
    • (2012) Curr Opin Oncol , vol.24 , Issue.5 , pp. 495-505
    • Uldrick, T.S.1    Polizzotto, M.N.2    Yarchoan, R.3
  • 70
    • 84907054332 scopus 로고    scopus 로고
    • CDCN. Available from: www. castlemannetwork. org
    • CDCN1
  • 71
    • 84900428111 scopus 로고    scopus 로고
    • First IL-6-blocking drug nears approval for rare blood disorder
    • Williams SC. First IL-6-blocking drug nears approval for rare blood disorder. Nat Med 2013;19(10):1193
    • (2013) Nat Med , vol.19 , Issue.10 , pp. 1193
    • Williams, S.C.1
  • 72
    • 84876196796 scopus 로고    scopus 로고
    • A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma
    • Voorhees PM, Manges RF, Sonneveld P, et al. A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma. Br J Haematol 2013;161(3):357-66
    • (2013) Br J Haematol , vol.161 , Issue.3 , pp. 357-366
    • Voorhees, P.M.1    Manges, R.F.2    Sonneveld, P.3
  • 73
    • 84903642514 scopus 로고    scopus 로고
    • Phase 2 randomized study of bortezomib-melphalan-prednisone with or without siltuximab (anti-IL-6) in multiple myeloma
    • San-Miguel J, Bladé J, Shpilberg O, et al. Phase 2 randomized study of bortezomib-melphalan-prednisone with or without siltuximab (anti-IL-6) in multiple myeloma. Blood 2014;123(26):4136-42
    • (2014) Blood , vol.123 , Issue.26 , pp. 4136-4142
    • San-Miguel, J.1    Bladé, J.2    Shpilberg, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.