-
1
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
22437870
-
D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12:252-64; PMID:22437870; http://dx.doi.org/10.1038/nrc3239
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
2
-
-
84899112560
-
Trial watch: immunostimulatory monoclonal antibodies in cancer therapy
-
24701370
-
F.Aranda, E.Vacchelli, A.Eggermont, J.Galon, W.H.Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory monoclonal antibodies in cancer therapy. Oncoimmunology 2014; 3:e27297; PMID:24701370; http://dx.doi.org/10.4161/onci.27297
-
(2014)
Oncoimmunology
, vol.3
, pp. 27297
-
-
Aranda, F.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Fridman, W.H.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
3
-
-
84902590227
-
Immune checkpoints: a therapeutic target in triple negative breast cancer
-
24843833
-
A.Chawla, A.V.Philips, G.Alatrash, E.Mittendorf. Immune checkpoints: a therapeutic target in triple negative breast cancer. Oncoimmunology 2014; 3:e28325; PMID:24843833; http://dx.doi.org/10.4161/onci.28325
-
(2014)
Oncoimmunology
, vol.3
, pp. 28325
-
-
Chawla, A.1
Philips, A.V.2
Alatrash, G.3
Mittendorf, E.4
-
4
-
-
84894499071
-
Immune checkpoint blockade: the hope for immunotherapy as a treatment of lung cancer?
-
24565586
-
J.R.Brahmer. Immune checkpoint blockade: the hope for immunotherapy as a treatment of lung cancer? Semin Oncol 2014; 41:126-32; PMID:24565586; http://dx.doi.org/10.1053/j.seminoncol.2013.12.014
-
(2014)
Semin Oncol
, vol.41
, pp. 126-132
-
-
Brahmer, J.R.1
-
5
-
-
78449243489
-
Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade
-
21074057
-
J.Weber. Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade. Semin Oncol 2010; 37:430-9; PMID:21074057; http://dx.doi.org/10.1053/j.seminoncol.2010.09.005
-
(2010)
Semin Oncol
, vol.37
, pp. 430-439
-
-
Weber, J.1
-
6
-
-
84884700351
-
Immunological checkpoint inhibitors enter adolescence
-
24035406
-
A.K.Nowak. Immunological checkpoint inhibitors enter adolescence. Lancet Oncol 2013; 14:1035-7; PMID:24035406; http://dx.doi.org/10.1016/S1470-2045(13)70401-7
-
(2013)
Lancet Oncol
, vol.14
, pp. 1035-1037
-
-
Nowak, A.K.1
-
7
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
20525992
-
F.S.Hodi, S.J.O’Day, D.F.McDermott, R.W.Weber, J.A.Sosman, J.B.Haanen, R.Gonzalez, C.Robert, D.Schadendorf, J.C.Hassel, Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363:711-23; PMID:20525992; http://dx.doi.org/10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O’Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
8
-
-
77955138291
-
Trial watch: ipilimumab success in melanoma provides boost for cancer immunotherapy
-
20671754
-
Trial watch: ipilimumab success in melanoma provides boost for cancer immunotherapy. Nat Rev Drug Discov 2010; 9:584; PMID:20671754; http://dx.doi.org/10.1038/nrd3245
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 584
-
-
-
9
-
-
75249083669
-
Immunity unleashed in melanoma
-
20152761
-
M.K.Erdmann. Immunity unleashed in melanoma. Lancet Oncol 2010; 11:108-9; PMID:20152761; http://dx.doi.org/10.1016/S1470-2045(09)70400-0
-
(2010)
Lancet Oncol
, vol.11
, pp. 108-109
-
-
Erdmann, M.K.1
-
10
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
-
20004617
-
J.D.Wolchok, B.Neyns, G.Linette, S.Negrier, J.Lutzky, L.Thomas, W.Waterfield, D.Schadendorf, M.Smylie, T.GuthrieJr, Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010; 11:155-64; PMID:20004617; http://dx.doi.org/10.1016/S1470-2045(09)70334-1
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
Negrier, S.4
Lutzky, J.5
Thomas, L.6
Waterfield, W.7
Schadendorf, D.8
Smylie, M.9
Guthrie, T.10
-
11
-
-
79957917538
-
Ipilimumab
-
21629286
-
V.K.Sondak, K.S.Smalley, R.Kudchadkar, S.Grippon, P.Kirkpatrick. Ipilimumab. Nat Rev Drug Discov 2011; 10:411-2; PMID:21629286; http://dx.doi.org/10.1038/nrd3463
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 411-412
-
-
Sondak, V.K.1
Smalley, K.S.2
Kudchadkar, R.3
Grippon, S.4
Kirkpatrick, P.5
-
12
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
7882171
-
T.L.Walunas, D.J.Lenschow, C.Y.Bakker, P.S.Linsley, G.J.Freeman, J.M.Green, C.B.Thompson, J.A.Bluestone. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1:405-13; PMID:7882171; http://dx.doi.org/10.1016/1074-7613(94)90071-X
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
13
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
7584144
-
E.A.Tivol, F.Borriello, A.N.Schweitzer, W.P.Lynch, J.A.Bluestone, A.H.Sharpe. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995; 3:541-7; PMID:7584144; http://dx.doi.org/10.1016/1074-7613(95)90125-6
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
14
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
7481803
-
P.Waterhouse, J.M.Penninger, E.Timms, A.Wakeham, A.Shahinian, K.P.Lee, C.B.Thompson, H.Griesser, T.W.Mak. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995; 270:985-8; PMID:7481803; http://dx.doi.org/10.1126/science.270.5238.985
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
15
-
-
84906510279
-
Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes
-
25083336
-
L.Robert, C.Harview, R.Emerson, X.Wang, S.Mok, B.Homet, B.Comin-Anduix, R.C.Koya, H.Robins, P.C.Tumeh, Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes. Oncoimmunology 2014; 3:e29244; PMID:25083336; http://dx.doi.org/10.4161/onci.29244
-
(2014)
Oncoimmunology
, vol.3
, pp. 29244
-
-
Robert, L.1
Harview, C.2
Emerson, R.3
Wang, X.4
Mok, S.5
Homet, B.6
Comin-Anduix, B.7
Koya, R.C.8
Robins, H.9
Tumeh, P.C.10
-
16
-
-
84899106840
-
Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo
-
24701377
-
L.C.Sandin, F.Eriksson, P.Ellmark, A.S.Loskog, T.H.Totterman, S.M.Mangsbo. Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo. Oncoimmunology 2014; 3:e27614; PMID:24701377; http://dx.doi.org/10.4161/onci.27614
-
(2014)
Oncoimmunology
, vol.3
, pp. 27614
-
-
Sandin, L.C.1
Eriksson, F.2
Ellmark, P.3
Loskog, A.S.4
Totterman, T.H.5
Mangsbo, S.M.6
-
17
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
25034862
-
C.Robert, A.Ribas, J.D.Wolchok, F.S.Hodi, O.Hamid, R.Kefford, J.S.Weber, A.M.Joshua, W.J.Hwu, T.C.Gangadhar, Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014; 384:1109-17; PMID:25034862; http://dx.doi.org/10.1016/S0140-6736(14)60958-2
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
Weber, J.S.7
Joshua, A.M.8
Hwu, W.J.9
Gangadhar, T.C.10
-
18
-
-
84907543029
-
Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL)
-
A.Ribas, F.S.Hodi, R.Kefford, O.Hamid, A.Daud, J.D.Wolchok, Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL). ASCO Meeting Abstr 2014; 32:LBA9000.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 9000
-
-
Ribas, A.1
Hodi, F.S.2
Kefford, R.3
Hamid, O.4
Daud, A.5
Wolchok, J.D.6
-
19
-
-
84904628107
-
Nivolumab: a review of its use in patients with malignant melanoma
-
25022950
-
E.D.Deeks. Nivolumab: a review of its use in patients with malignant melanoma. Drugs 2014; 74:1233-9; PMID:25022950; http://dx.doi.org/10.1007/s40265-014-0234-4
-
(2014)
Drugs
, vol.74
, pp. 1233-1239
-
-
Deeks, E.D.1
-
20
-
-
84906908933
-
Improved survival ends nivolumab trial early
-
25185170
-
Improved survival ends nivolumab trial early. Cancer Discov 2014; 4:979-80; PMID:25185170; http://dx.doi.org/10.1158/2159-8290.CD-NB2014-104
-
(2014)
Cancer Discov
, vol.4
, pp. 979-980
-
-
-
21
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
24590637
-
S.L.Topalian, M.Sznol, D.F.McDermott, H.M.Kluger, R.D.Carvajal, W.H.Sharfman, J.R.Brahmer, D.P.Lawrence, M.B.Atkins, J.D.Powderly, Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014; 32:1020-30; PMID:24590637; http://dx.doi.org/10.1200/JCO.2013.53.0105
-
(2014)
J Clin Oncol
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
Brahmer, J.R.7
Lawrence, D.P.8
Atkins, M.B.9
Powderly, J.D.10
-
22
-
-
84892866206
-
Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanoma
-
24145345
-
J.S.Weber, R.R.Kudchadkar, B.Yu, D.Gallenstein, C.E.Horak, H.D.Inzunza, X.Zhao, A.J.Martinez, W.Wang, G.Gibney, Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanoma. J Clin Oncol 2013; 31:4311-8; PMID:24145345; http://dx.doi.org/10.1200/JCO.2013.51.4802
-
(2013)
J Clin Oncol
, vol.31
, pp. 4311-4318
-
-
Weber, J.S.1
Kudchadkar, R.R.2
Yu, B.3
Gallenstein, D.4
Horak, C.E.5
Inzunza, H.D.6
Zhao, X.7
Martinez, A.J.8
Wang, W.9
Gibney, G.10
-
23
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
23724867
-
J.D.Wolchok, H.Kluger, M.K.Callahan, M.A.Postow, N.A.Rizvi, A.M.Lesokhin, N.H.Segal, C.E.Ariyan, R.A.Gordon, K.Reed, Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 2013; 369:122-33; PMID:23724867; http://dx.doi.org/10.1056/NEJMoa1302369
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
Segal, N.H.7
Ariyan, C.E.8
Gordon, R.A.9
Reed, K.10
-
24
-
-
84886943622
-
Re-orienting the immune system: durable tumor regression and successful re-induction therapy using anti-PD1 antibodies
-
23734322
-
E.J.Lipson. Re-orienting the immune system: durable tumor regression and successful re-induction therapy using anti-PD1 antibodies. Oncoimmunology 2013; 2:e23661; PMID:23734322; http://dx.doi.org/10.4161/onci.23661
-
(2013)
Oncoimmunology
, vol.2
, pp. 23661
-
-
Lipson, E.J.1
-
25
-
-
84906517328
-
PD-L1 expression and tumor-infiltrating lymphocytes: revisiting the antitumor immune response potential in breast cancer
-
25083339
-
K.A.Schalper. PD-L1 expression and tumor-infiltrating lymphocytes: revisiting the antitumor immune response potential in breast cancer. Oncoimmunology 2014; 3:e29288; PMID:25083339; http://dx.doi.org/10.4161/onci.29288
-
(2014)
Oncoimmunology
, vol.3
, pp. 29288
-
-
Schalper, K.A.1
-
26
-
-
84886945566
-
The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4 T cells
-
23734334
-
S.Munir, G.H.Andersen, I.M.Svane, M.H.Andersen. The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4 T cells. Oncoimmunology 2013; 2:e23991; PMID:23734334; http://dx.doi.org/10.4161/onci.23991
-
(2013)
Oncoimmunology
, vol.2
, pp. 23991
-
-
Munir, S.1
Andersen, G.H.2
Svane, I.M.3
Andersen, M.H.4
-
27
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
22658128
-
J.R.Brahmer, S.S.Tykodi, L.Q.Chow, W.J.Hwu, S.L.Topalian, P.Hwu, C.G.Drake, L.H.Camacho, J.Kauh, K.Odunsi, Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012; 366:2455-65; PMID:22658128; http://dx.doi.org/10.1056/NEJMoa1200694
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
-
28
-
-
84883219603
-
Trial watch: monoclonal antibodies in cancer therapy
-
23482847
-
E.Vacchelli, A.Eggermont, J.Galon, C.Sautes-Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: monoclonal antibodies in cancer therapy. Oncoimmunology 2013; 2:e22789; PMID:23482847; http://dx.doi.org/10.4161/onci.22789
-
(2013)
Oncoimmunology
, vol.2
, pp. 22789
-
-
Vacchelli, E.1
Eggermont, A.2
Galon, J.3
Sautes-Fridman, C.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
30
-
-
84890933630
-
Update on immune checkpoint inhibitors in lung cancer
-
24357746
-
B.C.Creelan. Update on immune checkpoint inhibitors in lung cancer. Cancer Control 2014; 21:80-9; PMID:24357746
-
(2014)
Cancer Control
, vol.21
, pp. 80-89
-
-
Creelan, B.C.1
-
31
-
-
84874830056
-
Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types
-
23460532
-
P.A.Ascierto, M.Kalos, D.A.Schaer, M.K.Callahan, J.D.Wolchok. Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types. Clin Cancer Res 2013; 19:1009-20; PMID:23460532; http://dx.doi.org/10.1158/1078-0432.CCR-12-2982
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1009-1020
-
-
Ascierto, P.A.1
Kalos, M.2
Schaer, D.A.3
Callahan, M.K.4
Wolchok, J.D.5
-
32
-
-
84907651084
-
Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC
-
J.R.Brahmer, N.A.Rizvi, J.Lutzky, S.Khleif, A.Blake-Haskins, X.Li, Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC. ASCO Meeting Abstr 2014; 32:8021.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8021
-
-
Brahmer, J.R.1
Rizvi, N.A.2
Lutzky, J.3
Khleif, S.4
Blake-Haskins, A.5
Li, X.6
-
33
-
-
84922634440
-
A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti-PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors
-
M.K.Callahan, P.A.Ott, K.Odunsi, S.V.Bertolini, L.S.Pan, R.R.Venhaus, A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti-PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors. ASCO Meeting Abstr 2014; 32:TPS3120.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3120
-
-
Callahan, M.K.1
Ott, P.A.2
Odunsi, K.3
Bertolini, S.V.4
Pan, L.S.5
Venhaus, R.R.6
-
34
-
-
84907532904
-
A phase 1 study of MEDI4736, an anti-PD-L1 antibody, in patients with advanced solid tumors
-
J.Lutzky, S.J.Antonia, A.Blake-Haskins, X.Li, P.B.Robbins, A.M.Shalabi, A phase 1 study of MEDI4736, an anti-PD-L1 antibody, in patients with advanced solid tumors. ASCO Meeting Abstr 2014; 32:3001.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3001
-
-
Lutzky, J.1
Antonia, S.J.2
Blake-Haskins, A.3
Li, X.4
Robbins, P.B.5
Shalabi, A.M.6
-
35
-
-
84907521154
-
Preliminary data from a multi-arm expansion study of MEDI4736, an anti-PD-L1 antibody
-
N.H.Segal, S.J.Antonia, J.R.Brahmer, M.Maio, A.Blake-Haskins, X.Li, Preliminary data from a multi-arm expansion study of MEDI4736, an anti-PD-L1 antibody. ASCO Meeting Abstr 2014; 32:3002.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3002
-
-
Segal, N.H.1
Antonia, S.J.2
Brahmer, J.R.3
Maio, M.4
Blake-Haskins, A.5
Li, X.6
-
36
-
-
84896698630
-
Cutaneous melanoma
-
24054424
-
A.M.Eggermont, A.Spatz, C.Robert. Cutaneous melanoma. Lancet 2014; 383:816-27; PMID:24054424; http://dx.doi.org/10.1016/S0140-6736(13)60802-8
-
(2014)
Lancet
, vol.383
, pp. 816-827
-
-
Eggermont, A.M.1
Spatz, A.2
Robert, C.3
-
37
-
-
84860490666
-
Intensifying tumour immunity through combination therapy
-
22326921
-
G.Dranoff. Intensifying tumour immunity through combination therapy. Lancet Oncol 2012; 13:440-2; PMID:22326921; http://dx.doi.org/10.1016/S1470-2045(12)70051-7
-
(2012)
Lancet Oncol
, vol.13
, pp. 440-442
-
-
Dranoff, G.1
-
38
-
-
84890285105
-
Inhibiting the inhibitors: checkpoints blockade in solid tumors
-
24244910
-
D.Mavilio, E.Lugli. Inhibiting the inhibitors: checkpoints blockade in solid tumors. Oncoimmunology 2013; 2:e26535; PMID:24244910; http://dx.doi.org/10.4161/onci.26535
-
(2013)
Oncoimmunology
, vol.2
, pp. 26535
-
-
Mavilio, D.1
Lugli, E.2
-
39
-
-
84880279552
-
Combination checkpoint blockade–taking melanoma immunotherapy to the next level
-
23724866
-
J.L.Riley. Combination checkpoint blockade–taking melanoma immunotherapy to the next level. N Engl J Med 2013; 369:187-9; PMID:23724866; http://dx.doi.org/10.1056/NEJMe1305484
-
(2013)
N Engl J Med
, vol.369
, pp. 187-189
-
-
Riley, J.L.1
-
40
-
-
84908327768
-
Melanoma: immune checkpoint blockade story gets better
-
25034863
-
S.Bhatia, J.A.Thompson. Melanoma: immune checkpoint blockade story gets better. Lancet 2014; 384:1078-9; PMID:25034863; http://dx.doi.org/10.1016/S0140-6736(14)61140-5
-
(2014)
Lancet
, vol.384
, pp. 1078-1079
-
-
Bhatia, S.1
Thompson, J.A.2
-
41
-
-
81155155667
-
Treatment of advanced melanoma with immunological checkpoint block
-
21938386
-
K.Margolin. Treatment of advanced melanoma with immunological checkpoint block. Curr Oncol Rep 2011; 13:430-2; PMID:21938386; http://dx.doi.org/10.1007/s11912-011-0195-7
-
(2011)
Curr Oncol Rep
, vol.13
, pp. 430-432
-
-
Margolin, K.1
-
42
-
-
84908127484
-
Melanoma: smart therapeutic strategies in immuno-oncology
-
24590131
-
A.M.Eggermont, C.Robert. Melanoma: smart therapeutic strategies in immuno-oncology. Nat Rev Clin Oncol 2014; 11:181-2; PMID:24590131; http://dx.doi.org/10.1038/nrclinonc.2014.36
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 181-182
-
-
Eggermont, A.M.1
Robert, C.2
-
43
-
-
84886945647
-
High frequency of T cells specific for cryptic epitopes in melanoma patients
-
24073381
-
R.S.Andersen, S.R.Andersen, M.D.Hjortso, R.Lyngaa, M.Idorn, T.M.Kollgard, O.Met, P.Thor Straten, S.R.Hadrup. High frequency of T cells specific for cryptic epitopes in melanoma patients. Oncoimmunology 2013; 2:e25374; PMID:24073381; http://dx.doi.org/10.4161/onci.25374
-
(2013)
Oncoimmunology
, vol.2
, pp. 25374
-
-
Andersen, R.S.1
Andersen, S.R.2
Hjortso, M.D.3
Lyngaa, R.4
Idorn, M.5
Kollgard, T.M.6
Met, O.7
Thor Straten, P.8
Hadrup, S.R.9
-
44
-
-
84899069873
-
The immune landscape of human tumors: implications for cancer immunotherapy
-
24800163
-
G.Bindea, B.Mlecnik, H.K.Angell, J.Galon. The immune landscape of human tumors: implications for cancer immunotherapy. Oncoimmunology 2014; 3:e27456; PMID:24800163; http://dx.doi.org/10.4161/onci.27456
-
(2014)
Oncoimmunology
, vol.3
, pp. 27456
-
-
Bindea, G.1
Mlecnik, B.2
Angell, H.K.3
Galon, J.4
-
45
-
-
84899104459
-
Harnessing the immune system to provide long-term survival in patients with melanoma and other solid tumors
-
24719793
-
A.Eggermont, C.Robert, J.C.Soria, L.Zitvogel. Harnessing the immune system to provide long-term survival in patients with melanoma and other solid tumors. Oncoimmunology 2014; 3:e27560; PMID:24719793; http://dx.doi.org/10.4161/onci.27560
-
(2014)
Oncoimmunology
, vol.3
, pp. 27560
-
-
Eggermont, A.1
Robert, C.2
Soria, J.C.3
Zitvogel, L.4
-
46
-
-
84934758039
-
Phase III, open-label study of nivolumab (anti-PD-1; BMS-936558, ONO-4538) as monotherapy or combined with ipilimumab in advanced or metastatic solid tumors
-
M.K.Callahan, J.C.Bendell, E.Chan, M.Morse, R.N.Pillai, P.Bono, Phase III, open-label study of nivolumab (anti-PD-1; BMS-936558, ONO-4538) as monotherapy or combined with ipilimumab in advanced or metastatic solid tumors. ASCO Meeting Abstr 2014; 32:TPS3114.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3114
-
-
Callahan, M.K.1
Bendell, J.C.2
Chan, E.3
Morse, M.4
Pillai, R.N.5
Bono, P.6
-
47
-
-
84912134974
-
Phase I open-label, multiple ascending dose trial of MSB0010718C, an anti-PD-L1 monoclonal antibody, in advanced solid malignancies
-
C.R.Heery, G.H.O’Sullivan Coyne, R.A.Madan, J.Schlom, A.von Heydebreck, J.-M.Cuillerot, Phase I open-label, multiple ascending dose trial of MSB0010718C, an anti-PD-L1 monoclonal antibody, in advanced solid malignancies. ASCO Meeting Abstr 2014; 32:3064.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3064
-
-
Heery, C.R.1
O’Sullivan Coyne, G.H.2
Madan, R.A.3
Schlom, J.4
von Heydebreck, A.5
Cuillerot, J.-M.6
-
48
-
-
84938602784
-
A multicohort trial of the safety and efficacy of the PD-1 inhibitor MK-3475 in patients with hematologic malignancies
-
G.Garcia-Manero, G.Martinelli, J.F.Zeidner, D.Avigan, K.C.Anderson, V.Ribrag, A multicohort trial of the safety and efficacy of the PD-1 inhibitor MK-3475 in patients with hematologic malignancies. ASCO Meeting Abstr 2014; 32:TPS3116.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3116
-
-
Garcia-Manero, G.1
Martinelli, G.2
Zeidner, J.F.3
Avigan, D.4
Anderson, K.C.5
Ribrag, V.6
-
49
-
-
84923101013
-
PD-L1 expression and genotype in non-small cell lung cancer (NSCLC)
-
S.Ansen, A.M.Schultheis, M.Hellmich, T.Zander, M.Brockmann, E.Stoelben, PD-L1 expression and genotype in non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2014; 32:7517.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 7517
-
-
Ansen, S.1
Schultheis, A.M.2
Hellmich, M.3
Zander, T.4
Brockmann, M.5
Stoelben, E.6
-
50
-
-
84880715077
-
Survival and long-term follow-up of the phase I trial of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in patients (pts) with previously treated advanced non-small cell lung cancer (NSCLC)
-
J.R.Brahmer, L.Horn, S.J.Antonia, D.R.Spigel, L.Gandhi, L.V.Sequist, Survival and long-term follow-up of the phase I trial of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in patients (pts) with previously treated advanced non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2013; 31:8030.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 8030
-
-
Brahmer, J.R.1
Horn, L.2
Antonia, S.J.3
Spigel, D.R.4
Gandhi, L.5
Sequist, L.V.6
-
51
-
-
84912130561
-
Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients (pts) with advanced non-small-cell lung cancer (NSCLC): survival and clinical activity by subgroup analysis
-
J.R.Brahmer, L.Horn, L.Gandhi, D.R.Spigel, S.J.Antonia, N.A.Rizvi, Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients (pts) with advanced non-small-cell lung cancer (NSCLC): survival and clinical activity by subgroup analysis. ASCO Meeting Abstr 2014; 32:8112.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8112
-
-
Brahmer, J.R.1
Horn, L.2
Gandhi, L.3
Spigel, D.R.4
Antonia, S.J.5
Rizvi, N.A.6
-
52
-
-
84930697267
-
Differential expression of LKB1, PD-L1, and PD-L2 in KRAS-mutant non-small cell lung cancer in never-smokers
-
A.Calles, X.Liao, L.M.Sholl, M.Butaney, S.J.Rodig, G.J.Freeman, Differential expression of LKB1, PD-L1, and PD-L2 in KRAS-mutant non-small cell lung cancer in never-smokers. ASCO Meeting Abstr 2014; 32:8032.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8032
-
-
Calles, A.1
Liao, X.2
Sholl, L.M.3
Butaney, M.4
Rodig, S.J.5
Freeman, G.J.6
-
53
-
-
84911864007
-
A phase III, randomized, open-label trial of nivolumab (anti-PD-1; BMS-936558, ONO-4538) versus investigator's choice chemotherapy (ICC) as first-line therapy for stage IV or recurrent PD-L1+ non-small cell lung cancer (NSCLC)
-
D.P.Carbone, M.A.Socinski, A.C.Chen, P.Bhagavatheeswaran, M.Reck, L.Paz-Ares. A phase III, randomized, open-label trial of nivolumab (anti-PD-1; BMS-936558, ONO-4538) versus investigator's choice chemotherapy (ICC) as first-line therapy for stage IV or recurrent PD-L1+ non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2014; 32:TPS8128.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8128
-
-
Carbone, D.P.1
Socinski, M.A.2
Chen, A.C.3
Bhagavatheeswaran, P.4
Reck, M.5
Paz-Ares, L.6
-
54
-
-
84907614647
-
Safety and clinical activity of MK-3475 in previously treated patients (pts) with non-small cell lung cancer (NSCLC)
-
E.B.Garon, N.B.Leighl, N.A.Rizvi, G.R.Blumenschein, A.S.Balmanoukian, J.P.Eder, Safety and clinical activity of MK-3475 in previously treated patients (pts) with non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2014; 32:8020.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8020
-
-
Garon, E.B.1
Leighl, N.B.2
Rizvi, N.A.3
Blumenschein, G.R.4
Balmanoukian, A.S.5
Eder, J.P.6
-
55
-
-
84880709088
-
Clinical activity, safety, and biomarkers of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
-
D.R.Spigel, S.N.Gettinger, L.Horn, R.S.Herbst, L.Gandhi, M.S.Gordon, Clinical activity, safety, and biomarkers of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2013; 31:8008.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 8008
-
-
Spigel, D.R.1
Gettinger, S.N.2
Horn, L.3
Herbst, R.S.4
Gandhi, L.5
Gordon, M.S.6
-
56
-
-
84905107303
-
PD-L1 expression in primary clear cell renal cell carcinomas (ccRCCs) and their metastases
-
M.Callea, E.M.Genega, M.Gupta, S.Cheng, A.P.Fay, J.Song, PD-L1 expression in primary clear cell renal cell carcinomas (ccRCCs) and their metastases. ASCO Meeting Abstr 2014; 32:4585.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 4585
-
-
Callea, M.1
Genega, E.M.2
Gupta, M.3
Cheng, S.4
Fay, A.P.5
Song, J.6
-
57
-
-
84905107303
-
PD-L1 expression in primary clear cell renal cell carcinomas (ccRCCs) and their metastases
-
M.Callea, E.M.Genega, M.Gupta, A.P.Fay, J.Song, I.Carvo, PD-L1 expression in primary clear cell renal cell carcinomas (ccRCCs) and their metastases. ASCO Meeting Abstr 2014; 32:467.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 467
-
-
Callea, M.1
Genega, E.M.2
Gupta, M.3
Fay, A.P.4
Song, J.5
Carvo, I.6
-
58
-
-
84921742040
-
Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): biomarker-based results from a randomized clinical trial
-
T.K.Choueiri, M.N.Fishman, B.J.Escudier, J.J.Kim, H.M.Kluger, W.M.Stadler, Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): biomarker-based results from a randomized clinical trial. ASCO Meeting Abstr 2014; 32:5012.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 5012
-
-
Choueiri, T.K.1
Fishman, M.N.2
Escudier, B.J.3
Kim, J.J.4
Kluger, H.M.5
Stadler, W.M.6
-
59
-
-
84880706331
-
Survival, safety, and response duration results of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in a phase I trial in patients with previously treated metastatic renal cell carcinoma (mRCC): long-term patient follow-up
-
C.G.Drake, D.F.McDermott, M.Sznol, T.K.Choueiri, H.M.Kluger, J.D.Powderly, Survival, safety, and response duration results of nivolumab (Anti-PD-1; BMS-936558; ONO-4538) in a phase I trial in patients with previously treated metastatic renal cell carcinoma (mRCC): long-term patient follow-up. ASCO Meeting Abstr 2013; 31:4514.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 4514
-
-
Drake, C.G.1
McDermott, D.F.2
Sznol, M.3
Choueiri, T.K.4
Kluger, H.M.5
Powderly, J.D.6
-
60
-
-
84938595611
-
PD-L1 expression in non-clear cell renal cell carcinoma and benign kidney tumors
-
A.P.Fay, M.Callea, K.P.Gray, T.H.Ho, J.Song, I.Carvo, PD-L1 expression in non-clear cell renal cell carcinoma and benign kidney tumors. ASCO Meeting Abstr 2014; 32:4526.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 4526
-
-
Fay, A.P.1
Callea, M.2
Gray, K.P.3
Ho, T.H.4
Song, J.5
Carvo, I.6
-
61
-
-
84938558787
-
PD-L1 expression and immune infiltrates in sarcoma
-
S.P.D’Angelo, A.N.Shoushtari, N.P.Agaram, D.Kuk, L.-X.Qin, R.D.Carvajal, PD-L1 expression and immune infiltrates in sarcoma. ASCO Meeting Abstr 2014; 32:10522.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 10522
-
-
D’Angelo, S.P.1
Shoushtari, A.N.2
Agaram, N.P.3
Kuk, D.4
Qin, L.-X.5
Carvajal, R.D.6
-
62
-
-
84938648665
-
PD-L1 specific tumor infiltrating lymphocytes occur frequently in melanoma and HNSCC patients
-
N.Junker, M.Donia, R.Andersen, M.H.Andersen, I.M.Svane. PD-L1 specific tumor infiltrating lymphocytes occur frequently in melanoma and HNSCC patients. ASCO Meeting Abstr 2014; 32:11083.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 11083
-
-
Junker, N.1
Donia, M.2
Andersen, R.3
Andersen, M.H.4
Svane, I.M.5
-
63
-
-
84907521155
-
A phase Ib study of MK-3475 in patients with human papillomavirus (HPV)-associated and non-HPV-associated head and neck (HN) cancer
-
T.Y.Seiwert, B.Burtness, J.Weiss, I.Gluck, J.P.Eder, S.I.Pai, A phase Ib study of MK-3475 in patients with human papillomavirus (HPV)-associated and non-HPV-associated head and neck (HN) cancer. ASCO Meeting Abstr 2014; 32:6011.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 6011
-
-
Seiwert, T.Y.1
Burtness, B.2
Weiss, J.3
Gluck, I.4
Eder, J.P.5
Pai, S.I.6
-
64
-
-
84905753981
-
Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer
-
J.Hamanishi, M.Mandai, T.Ikeda, M.Minami, A.Kawaguchi, N.Matsumura, Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer. ASCO Meeting Abstr 2014; 32:5511.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 5511
-
-
Hamanishi, J.1
Mandai, M.2
Ikeda, T.3
Minami, M.4
Kawaguchi, A.5
Matsumura, N.6
-
65
-
-
84905698694
-
Inhibition of PD-L1 by MPDL3280A and clinical activity in pts with metastatic urothelial bladder cancer (UBC)
-
T.Powles, N.J.Vogelzang, G.D.Fine, J.P.Eder, F.S.Braiteh, Y.Loriot, Inhibition of PD-L1 by MPDL3280A and clinical activity in pts with metastatic urothelial bladder cancer (UBC). ASCO Meeting Abstr 2014; 32:5011.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 5011
-
-
Powles, T.1
Vogelzang, N.J.2
Fine, G.D.3
Eder, J.P.4
Braiteh, F.S.5
Loriot, Y.6
-
66
-
-
84938648666
-
Programmed death receptor ligand-1 (PD-L1) expression in a thymoma (T) tissue microarray (TMA)
-
S.K.Padda, J.Riess, E.J.Schwartz, L.Tian, H.E.Kohrt, J.W.Neal, Programmed death receptor ligand-1 (PD-L1) expression in a thymoma (T) tissue microarray (TMA). ASCO Meeting Abstr 2014; 32:7606.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 7606
-
-
Padda, S.K.1
Riess, J.2
Schwartz, E.J.3
Tian, L.4
Kohrt, H.E.5
Neal, J.W.6
-
67
-
-
84938648667
-
Immune checkpoints expression in MSI versus MSS colorectal cancers and their potential therapeutic implications
-
N.J.Llosa, F.Housseau, E.C.Wick, L.Hechenbleikner, M.Cruise, R.Anders, Immune checkpoints expression in MSI versus MSS colorectal cancers and their potential therapeutic implications. ASCO Meeting Abstr 2014; 32:3620.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3620
-
-
Llosa, N.J.1
Housseau, F.2
Wick, E.C.3
Hechenbleikner, L.4
Cruise, M.5
Anders, R.6
-
68
-
-
84906489918
-
Trial watch: immunostimulatory cytokines in cancer therapy
-
25083328
-
E.Vacchelli, F.Aranda, F.Obrist, A.Eggermont, J.Galon, I.Cremer, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory cytokines in cancer therapy. Oncoimmunology 2014; 3:e29030; PMID:25083328; http://dx.doi.org/10.4161/onci.29030
-
(2014)
Oncoimmunology
, vol.3
, pp. 29030
-
-
Vacchelli, E.1
Aranda, F.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Cremer, I.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
69
-
-
84886943238
-
Trial watch: immunostimulatory cytokines
-
24073369
-
E.Vacchelli, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory cytokines. Oncoimmunology 2013; 2:e24850; PMID:24073369; http://dx.doi.org/10.4161/onci.24850
-
(2013)
Oncoimmunology
, vol.2
, pp. 24850
-
-
Vacchelli, E.1
Eggermont, A.2
Fridman, W.H.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
70
-
-
84860436621
-
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
-
22326922
-
A.J.van den Eertwegh, J.Versluis, H.P.van den Berg, S.J.Santegoets, R.J.van Moorselaar, T.M.van der Sluis, H.E.Gall, T.C.Harding, K.Jooss, I.Lowy, Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. Lancet Oncol 2012; 13:509-17; PMID:22326922; http://dx.doi.org/10.1016/S1470-2045(12)70007-4
-
(2012)
Lancet Oncol
, vol.13
, pp. 509-517
-
-
van den Eertwegh, A.J.1
Versluis, J.2
van den Berg, H.P.3
Santegoets, S.J.4
van Moorselaar, R.J.5
van der Sluis, T.M.6
Gall, H.E.7
Harding, T.C.8
Jooss, K.9
Lowy, I.10
-
71
-
-
84902449791
-
Combined OX40 ligation plus CTLA-4 blockade: more than the sum of its parts
-
25050194
-
S.N.Linch, W.L.Redmond. Combined OX40 ligation plus CTLA-4 blockade: more than the sum of its parts. Oncoimmunology 2014; 3:e28245; PMID:25050194; http://dx.doi.org/10.4161/onci.28245
-
(2014)
Oncoimmunology
, vol.3
, pp. 28245
-
-
Linch, S.N.1
Redmond, W.L.2
-
72
-
-
84904609350
-
Blockade of PD-1 immunosuppression boosts CAR T-cell therapy
-
24353912
-
L.B.John, M.H.Kershaw, P.K.Darcy. Blockade of PD-1 immunosuppression boosts CAR T-cell therapy. Oncoimmunology 2013; 2:e26286; PMID:24353912; http://dx.doi.org/10.4161/onci.26286
-
(2013)
Oncoimmunology
, vol.2
, pp. 26286
-
-
John, L.B.1
Kershaw, M.H.2
Darcy, P.K.3
-
73
-
-
84886397930
-
Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells
-
23873688
-
L.B.John, C.Devaud, C.P.Duong, C.S.Yong, P.A.Beavis, N.M.Haynes, M.T.Chow, M.J.Smyth, M.H.Kershaw, P.K.Darcy. Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells. Clin Cancer Res 2013; 19:5636-46; PMID:23873688; http://dx.doi.org/10.1158/1078-0432.CCR-13-0458
-
(2013)
Clin Cancer Res
, vol.19
, pp. 5636-5646
-
-
John, L.B.1
Devaud, C.2
Duong, C.P.3
Yong, C.S.4
Beavis, P.A.5
Haynes, N.M.6
Chow, M.T.7
Smyth, M.J.8
Kershaw, M.H.9
Darcy, P.K.10
-
74
-
-
84885162273
-
Trial watch: adoptive cell transfer for anticancer immunotherapy
-
23762803
-
E.Vacchelli, A.Eggermont, W.H.Fridman, J.Galon, E.Tartour, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: adoptive cell transfer for anticancer immunotherapy. Oncoimmunology 2013; 2:e24238; PMID:23762803; http://dx.doi.org/10.4161/onci.24238
-
(2013)
Oncoimmunology
, vol.2
, pp. 24238
-
-
Vacchelli, E.1
Eggermont, A.2
Fridman, W.H.3
Galon, J.4
Tartour, E.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
75
-
-
84904060047
-
Trial watch: adoptive cell transfer for anticancer immunotherapy
-
25050207
-
F.Aranda, E.Vacchelli, F.Obrist, A.Eggermont, J.Galon, W.Herve Fridman, I.Cremer, E.Tartour, L.Zitvogel, G.Kroemer, Trial watch: adoptive cell transfer for anticancer immunotherapy. Oncoimmunology 2014; 3:e28344; PMID:25050207; http://dx.doi.org/10.4161/onci.28344
-
(2014)
Oncoimmunology
, vol.3
, pp. 28344
-
-
Aranda, F.1
Vacchelli, E.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Herve Fridman, W.6
Cremer, I.7
Tartour, E.8
Zitvogel, L.9
Kroemer, G.10
-
76
-
-
84883230583
-
Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer
-
23524510
-
W.Peng, G.Lizee, P.Hwu. Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer. Oncoimmunology 2013; 2:e22691; PMID:23524510; http://dx.doi.org/10.4161/onci.22691
-
(2013)
Oncoimmunology
, vol.2
, pp. 22691
-
-
Peng, W.1
Lizee, G.2
Hwu, P.3
-
77
-
-
84867544962
-
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines
-
22915761
-
W.Peng, C.Liu, C.Xu, Y.Lou, J.Chen, Y.Yang, H.Yagita, W.W.Overwijk, G.Lizée, L.Radvanyi, PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines. Cancer Res 2012; 72:5209-18; PMID:22915761; http://dx.doi.org/10.1158/0008-5472.CAN-12-1187
-
(2012)
Cancer Res
, vol.72
, pp. 5209-5218
-
-
Peng, W.1
Liu, C.2
Xu, C.3
Lou, Y.4
Chen, J.5
Yang, Y.6
Yagita, H.7
Overwijk, W.W.8
Lizée, G.9
Radvanyi, L.10
-
78
-
-
84890254287
-
Trial watch: dendritic cell-based interventions for cancer therapy
-
24286020
-
E.Vacchelli, I.Vitale, A.Eggermont, W.H.Fridman, J.Fucikova, I.Cremer, J.Galon, E.Tartour, L.Zitvogel, G.Kroemer, Trial watch: dendritic cell-based interventions for cancer therapy. Oncoimmunology 2013; 2:e25771; PMID:24286020; http://dx.doi.org/10.4161/onci.25771
-
(2013)
Oncoimmunology
, vol.2
, pp. 25771
-
-
Vacchelli, E.1
Vitale, I.2
Eggermont, A.3
Fridman, W.H.4
Fucikova, J.5
Cremer, I.6
Galon, J.7
Tartour, E.8
Zitvogel, L.9
Kroemer, G.10
-
79
-
-
84938566015
-
Trial Watch: dendritic cell-based anticancer therapy
-
in press
-
N.Bloy, J.Pol, F.Aranda, A.Eggermont, I.Cremer, W.H.Fridman, J.Galon, C.Sautès-Fridman, E.Tartour, L.Zitvogel, Trial Watch: dendritic cell-based anticancer therapy. Oncoimmunology 2014; 3:in press.
-
(2014)
Oncoimmunology
, vol.3
-
-
Bloy, N.1
Pol, J.2
Aranda, F.3
Eggermont, A.4
Cremer, I.5
Fridman, W.H.6
Galon, J.7
Sautès-Fridman, C.8
Tartour, E.9
Zitvogel, L.10
-
80
-
-
84860455345
-
Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
-
22326924
-
R.A.Madan, M.Mohebtash, P.M.Arlen, M.Vergati, M.Rauckhorst, S.M.Steinberg, K.Y.Tsang, D.J.Poole, H.L.Parnes, J.J.Wright, Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. Lancet Oncol 2012; 13:501-8; PMID:22326924; http://dx.doi.org/10.1016/S1470-2045(12)70006-2
-
(2012)
Lancet Oncol
, vol.13
, pp. 501-508
-
-
Madan, R.A.1
Mohebtash, M.2
Arlen, P.M.3
Vergati, M.4
Rauckhorst, M.5
Steinberg, S.M.6
Tsang, K.Y.7
Poole, D.J.8
Parnes, H.L.9
Wright, J.J.10
-
81
-
-
84880721353
-
Dendritic-cell-based therapeutic cancer vaccines
-
23890062
-
K.Palucka, J.Banchereau. Dendritic-cell-based therapeutic cancer vaccines. Immunity 2013; 39:38-48; PMID:23890062; http://dx.doi.org/10.1016/j.immuni.2013.07.004
-
(2013)
Immunity
, vol.39
, pp. 38-48
-
-
Palucka, K.1
Banchereau, J.2
-
82
-
-
84885432340
-
Trial watch: DNA vaccines for cancer therapy
-
23734328
-
L.Senovilla, E.Vacchelli, P.Garcia, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: DNA vaccines for cancer therapy. Oncoimmunology 2013; 2:e23803; PMID:23734328; http://dx.doi.org/10.4161/onci.23803
-
(2013)
Oncoimmunology
, vol.2
, pp. 23803
-
-
Senovilla, L.1
Vacchelli, E.2
Garcia, P.3
Eggermont, A.4
Fridman, W.H.5
Galon, J.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
83
-
-
84902593489
-
Trial watch: DNA vaccines for cancer therapy
-
24800178
-
J.Pol, N.Bloy, F.Obrist, A.Eggermont, J.Galon, Herve W.Fridman, I.Cremer, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: DNA vaccines for cancer therapy. Oncoimmunology 2014; 3:e28185; PMID:24800178; http://dx.doi.org/10.4161/onci.28185
-
(2014)
Oncoimmunology
, vol.3
, pp. 28185
-
-
Pol, J.1
Bloy, N.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Fridman, W.6
Cremer, I.7
Zitvogel, L.8
Kroemer, G.9
Galluzzi, L.10
-
84
-
-
84894553314
-
Trial watch: peptide vaccines in cancer therapy
-
24498550
-
F.Aranda, E.Vacchelli, A.Eggermont, J.Galon, C.Sautes-Fridman, E.Tartour, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: peptide vaccines in cancer therapy. Oncoimmunology 2013; 2:e26621; PMID:24498550; http://dx.doi.org/10.4161/onci.26621
-
(2013)
Oncoimmunology
, vol.2
, pp. 26621
-
-
Aranda, F.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Sautes-Fridman, C.5
Tartour, E.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
85
-
-
79957891364
-
PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cellmyeloma fusion vaccine
-
21577144
-
J.Rosenblatt, B.Glotzbecker, H.Mills, B.Vasir, D.Tzachanis, J.D.Levine, R.M.Joyce, K.Wellenstein, W.Keefe, M.Schickler, PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cellmyeloma fusion vaccine. J Immunother 2011; 34:409-18; PMID:21577144; http://dx.doi.org/10.1097/CJI.0b013e31821ca6ce
-
(2011)
J Immunother
, vol.34
, pp. 409-418
-
-
Rosenblatt, J.1
Glotzbecker, B.2
Mills, H.3
Vasir, B.4
Tzachanis, D.5
Levine, J.D.6
Joyce, R.M.7
Wellenstein, K.8
Keefe, W.9
Schickler, M.10
-
86
-
-
84908299923
-
Updated survival, toxicity, and biomarkers of nivolumab withwithout peptide vaccine in patients naive to, or progressed on, ipilimumab (IPI)
-
J.S.Weber, R.R.Kudchadkar, G.T.Gibney, B.Yu, P.Cheng, A.J.Martinez, Updated survival, toxicity, and biomarkers of nivolumab withwithout peptide vaccine in patients naive to, or progressed on, ipilimumab (IPI). ASCO Meeting Abstr 2014; 32:3009.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3009
-
-
Weber, J.S.1
Kudchadkar, R.R.2
Gibney, G.T.3
Yu, B.4
Cheng, P.5
Martinez, A.J.6
-
87
-
-
84906871563
-
Trial watch: toll-like receptor agonists in oncological indications
-
25083332
-
F.Aranda, E.Vacchelli, F.Obrist, A.Eggermont, J.Galon, C.Sautes-Fridman, I.Cremer, J.Henrik Ter Meulen, L.Zitvogel, G.Kroemer, Trial watch: toll-like receptor agonists in oncological indications. Oncoimmunology 2014; 3:e29179; PMID:25083332; http://dx.doi.org/10.4161/onci.29179
-
(2014)
Oncoimmunology
, vol.3
, pp. 29179
-
-
Aranda, F.1
Vacchelli, E.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Sautes-Fridman, C.6
Cremer, I.7
Henrik Ter Meulen, J.8
Zitvogel, L.9
Kroemer, G.10
-
88
-
-
84885696781
-
Trial watch: toll-like receptor agonists for cancer therapy
-
24083080
-
E.Vacchelli, A.Eggermont, C.Sautes-Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: toll-like receptor agonists for cancer therapy. Oncoimmunology 2013; 2:e25238; PMID:24083080; http://dx.doi.org/10.4161/onci.25238
-
(2013)
Oncoimmunology
, vol.2
, pp. 25238
-
-
Vacchelli, E.1
Eggermont, A.2
Sautes-Fridman, C.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
89
-
-
84904045263
-
A novel combinatorial cancer immunotherapy: poly-IC and blockade of the PD-1PD-L1 pathway
-
25050210
-
T.Nagato, E.Celis. A novel combinatorial cancer immunotherapy: poly-IC and blockade of the PD-1PD-L1 pathway. Oncoimmunology 2014; 3:e28440; PMID:25050210; http://dx.doi.org/10.4161/onci.28440
-
(2014)
Oncoimmunology
, vol.3
, pp. 28440
-
-
Nagato, T.1
Celis, E.2
-
90
-
-
84893877031
-
Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma
-
24777500
-
C.A.Barker, M.A.Postow, S.A.Khan, K.Beal, P.K.Parhar, Y.Yamada, N.Y.Lee, J.D.Wolchok. Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma. Cancer Immunol Res 2013; 1:92-8; PMID:24777500; http://dx.doi.org/10.1158/2326-6066.CIR-13-0082
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 92-98
-
-
Barker, C.A.1
Postow, M.A.2
Khan, S.A.3
Beal, K.4
Parhar, P.K.5
Yamada, Y.6
Lee, N.Y.7
Wolchok, J.D.8
-
91
-
-
84934317841
-
Trial watch: radioimmunotherapy for oncological indications
-
in press
-
N.Bloy, J.Pol, G.Manic, I.Vitale, A.Eggermont, J.Galon, Trial watch: radioimmunotherapy for oncological indications. Oncoimmunology 2014; 3:in press.
-
(2014)
Oncoimmunology
, vol.3
-
-
Bloy, N.1
Pol, J.2
Manic, G.3
Vitale, I.4
Eggermont, A.5
Galon, J.6
-
92
-
-
84885754733
-
Trial watch: anticancer radioimmunotherapy
-
24319634
-
E.Vacchelli, I.Vitale, E.Tartour, A.Eggermont, C.Sautes-Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: anticancer radioimmunotherapy. Oncoimmunology 2013; 2:e25595; PMID:24319634
-
(2013)
Oncoimmunology
, vol.2
, pp. 25595
-
-
Vacchelli, E.1
Vitale, I.2
Tartour, E.3
Eggermont, A.4
Sautes-Fridman, C.5
Galon, J.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
93
-
-
84904216679
-
Ipilimumab and radiation therapy for melanoma brain metastases
-
24403263
-
A.W.Silk, M.F.Bassetti, B.T.West, C.I.Tsien, C.D.Lao. Ipilimumab and radiation therapy for melanoma brain metastases. Cancer Med 2013; 2:899-906; PMID:24403263; http://dx.doi.org/10.1002/cam4.140
-
(2013)
Cancer Med
, vol.2
, pp. 899-906
-
-
Silk, A.W.1
Bassetti, M.F.2
West, B.T.3
Tsien, C.I.4
Lao, C.D.5
-
94
-
-
84861398744
-
Abscopal effect in a patient with melanoma
-
author reply -6, 22621637
-
S.M.Hiniker, D.S.Chen, S.J.Knox. Abscopal effect in a patient with melanoma. N Engl J Med 2012; 366:2035; author reply -6; PMID:22621637; http://dx.doi.org/10.1056/NEJMc1203984
-
(2012)
N Engl J Med
, vol.366
, pp. 2035
-
-
Hiniker, S.M.1
Chen, D.S.2
Knox, S.J.3
-
95
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
22397654
-
M.A.Postow, M.K.Callahan, C.A.Barker, Y.Yamada, J.Yuan, S.Kitano, Z.Mu, T.Rasalan, M.Adamow, E.Ritter, Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med 2012; 366:925-31; PMID:22397654; http://dx.doi.org/10.1056/NEJMoa1112824
-
(2012)
N Engl J Med
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
Yamada, Y.4
Yuan, J.5
Kitano, S.6
Mu, Z.7
Rasalan, T.8
Adamow, M.9
Ritter, E.10
-
96
-
-
84886944998
-
Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment
-
23802063
-
S.Demaria, K.A.Pilones, S.C.Formenti, M.L.Dustin. Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment. Oncoimmunology 2013; 2:e23127; PMID:23802063; http://dx.doi.org/10.4161/onci.23127
-
(2013)
Oncoimmunology
, vol.2
, pp. 23127
-
-
Demaria, S.1
Pilones, K.A.2
Formenti, S.C.3
Dustin, M.L.4
-
97
-
-
84885692390
-
Trial watch: chemotherapy with immunogenic cell death inducers
-
23687621
-
E.Vacchelli, L.Senovilla, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: chemotherapy with immunogenic cell death inducers. Oncoimmunology 2013; 2:e23510; PMID:23687621; http://dx.doi.org/10.4161/onci.23510
-
(2013)
Oncoimmunology
, vol.2
, pp. 23510
-
-
Vacchelli, E.1
Senovilla, L.2
Eggermont, A.3
Fridman, W.H.4
Galon, J.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
98
-
-
84902504669
-
Trial watch: chemotherapy with immunogenic cell death inducers
-
24800173
-
E.Vacchelli, F.Aranda, A.Eggermont, J.Galon, C.Sautes-Fridman, I.Cremer, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: chemotherapy with immunogenic cell death inducers. Oncoimmunology 2014; 3:e27878; PMID:24800173; http://dx.doi.org/10.4161/onci.27878
-
(2014)
Oncoimmunology
, vol.3
, pp. 27878
-
-
Vacchelli, E.1
Aranda, F.2
Eggermont, A.3
Galon, J.4
Sautes-Fridman, C.5
Cremer, I.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
99
-
-
84857789296
-
The secret ally: immunostimulation by anticancer drugs
-
22301798
-
L.Galluzzi, L.Senovilla, L.Zitvogel, G.Kroemer. The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov 2012; 11:215-33; PMID:22301798; http://dx.doi.org/10.1038/nrd3626
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 215-233
-
-
Galluzzi, L.1
Senovilla, L.2
Zitvogel, L.3
Kroemer, G.4
-
100
-
-
84880747672
-
Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
-
23890065
-
L.Zitvogel, L.Galluzzi, M.J.Smyth, G.Kroemer. Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity 2013; 39:74-88; PMID:23890065; http://dx.doi.org/10.1016/j.immuni.2013.06.014
-
(2013)
Immunity
, vol.39
, pp. 74-88
-
-
Zitvogel, L.1
Galluzzi, L.2
Smyth, M.J.3
Kroemer, G.4
-
101
-
-
84886944616
-
Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma
-
23762807
-
Z.A.Cooper, D.T.Frederick, Z.Ahmed, J.A.Wargo. Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma. Oncoimmunology 2013; 2:e24320; PMID:23762807; http://dx.doi.org/10.4161/onci.24320
-
(2013)
Oncoimmunology
, vol.2
, pp. 24320
-
-
Cooper, Z.A.1
Frederick, D.T.2
Ahmed, Z.3
Wargo, J.A.4
-
102
-
-
84896730538
-
A phase I study of nivolumab (anti-PD-1; BMS-936558; ONO-4538) in combination with sunitinib, pazopanib, or ipilimumab in patients (pts) with metastatic renal cell carcinoma (mRCC)
-
A.Amin, M.S.Ernstoff, J.R.Infante, Heng DYC, B.I.Rini, E.R.Plimack, A phase I study of nivolumab (anti-PD-1; BMS-936558; ONO-4538) in combination with sunitinib, pazopanib, or ipilimumab in patients (pts) with metastatic renal cell carcinoma (mRCC). ASCO Meeting Abstr 2013; 31:TPS4593.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 4593
-
-
Amin, A.1
Ernstoff, M.S.2
Infante, J.R.3
Rini, B.I.4
Plimack, E.R.5
-
103
-
-
84914176528
-
Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with sunitinib or pazopanib in patients (pts) with metastatic renal cell carcinoma (mRCC)
-
A.Amin, E.R.Plimack, J.R.Infante, M.S.Ernstoff, B.I.Rini, D.F.McDermott, Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with sunitinib or pazopanib in patients (pts) with metastatic renal cell carcinoma (mRCC). ASCO Meeting Abstr 2014; 32:5010.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 5010
-
-
Amin, A.1
Plimack, E.R.2
Infante, J.R.3
Ernstoff, M.S.4
Rini, B.I.5
McDermott, D.F.6
-
104
-
-
84908269560
-
Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with platinum-based doublet chemotherapy (PT-DC) in advanced non-small cell lung cancer (NSCLC)
-
S.J.Antonia, J.R.Brahmer, S.N.Gettinger, L.Q.M.Chow, R.A.Juergens, F.A.Shepherd, Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with platinum-based doublet chemotherapy (PT-DC) in advanced non-small cell lung cancer (NSCLC). ASCO Meeting Abstr 2014; 32:8113.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8113
-
-
Antonia, S.J.1
Brahmer, J.R.2
Gettinger, S.N.3
Chow, L.Q.M.4
Juergens, R.A.5
Shepherd, F.A.6
-
105
-
-
84916895694
-
Updated overall survival (OS) for BRF113220, a phase 1-2 study of dabrafenib (D) alone versus combined dabrafenib and trametinib (D+T) in pts with BRAF V600 mutation-positive (+) metastatic melanoma (MM)
-
K.Flaherty, A.Daud, J.S.Weber, J.A.Sosman, K.Kim, R.Gonzalez, Updated overall survival (OS) for BRF113220, a phase 1-2 study of dabrafenib (D) alone versus combined dabrafenib and trametinib (D+T) in pts with BRAF V600 mutation-positive (+) metastatic melanoma (MM). ASCO Meeting Abstr 2014; 32:9010.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 9010
-
-
Flaherty, K.1
Daud, A.2
Weber, J.S.3
Sosman, J.A.4
Kim, K.5
Gonzalez, R.6
-
106
-
-
84942196770
-
A phase III study to assess the safety and efficacy of pazopanib and MK-3475 in subjects with advanced renal cell carcinoma
-
D.F.McDermott, J.R.Infante, M.H.Voss, R.J.Motzer, J.B.A.G.Haanen, S.Chowdhury, A phase III study to assess the safety and efficacy of pazopanib and MK-3475 in subjects with advanced renal cell carcinoma. ASCO Meeting Abstr 2014; 32:TPS4604.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 4604
-
-
McDermott, D.F.1
Infante, J.R.2
Voss, M.H.3
Motzer, R.J.4
Haanen, J.B.A.G.5
Chowdhury, S.6
-
107
-
-
84938648668
-
An open-label, phase 1b, dose-escalation study (CA180-373) of dasatinib plus nivolumab, an investigational anti-programmed cell death 1 (PD-1) antibody, in patients (pts) with previously treated chronic myeloid leukemia (CML)
-
K.Porkka, M.J.Mauro, J.H.Lipton, F.-X.Mahon, L.C.Strauss, W.J.Geese, An open-label, phase 1b, dose-escalation study (CA180-373) of dasatinib plus nivolumab, an investigational anti-programmed cell death 1 (PD-1) antibody, in patients (pts) with previously treated chronic myeloid leukemia (CML). ASCO Meeting Abstr 2014; 32:TPS7119.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 7119
-
-
Porkka, K.1
Mauro, M.J.2
Lipton, J.H.3
Mahon, F.-X.4
Strauss, L.C.5
Geese, W.J.6
-
108
-
-
84907651085
-
Safety and response with nivolumab (anti-PD-1; BMS-936558, ONO-4538) plus erlotinib in patients (pts) with epidermal growth factor receptor mutant (EGFR MT) advanced NSCLC
-
N.A.Rizvi, L.Q.M.Chow, H.Borghaei, Y.Shen, C.Harbison, S.Alaparthy, Safety and response with nivolumab (anti-PD-1; BMS-936558, ONO-4538) plus erlotinib in patients (pts) with epidermal growth factor receptor mutant (EGFR MT) advanced NSCLC. ASCO Meeting Abstr 2014; 32:8022.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 8022
-
-
Rizvi, N.A.1
Chow, L.Q.M.2
Borghaei, H.3
Shen, Y.4
Harbison, C.5
Alaparthy, S.6
-
109
-
-
85027956453
-
Thunder and lightning: immunotherapy and oncolytic viruses collide
-
21505424
-
A.Melcher, K.Parato, C.M.Rooney, J.C.Bell. Thunder and lightning: immunotherapy and oncolytic viruses collide. Mol Ther 2011; 19:1008-16; PMID:21505424; http://dx.doi.org/10.1038/mt.2011.65
-
(2011)
Mol Ther
, vol.19
, pp. 1008-1016
-
-
Melcher, A.1
Parato, K.2
Rooney, C.M.3
Bell, J.C.4
-
110
-
-
84906483079
-
Trial watch: oncolytic viruses for cancer therapy
-
25097804
-
J.Pol, N.Bloy, F.Obrist, A.Eggermont, J.Galon, I.Cremer, P.Erbs, J.M.Limacher, X.Preville, L.Zitvogel, Trial watch: oncolytic viruses for cancer therapy. Oncoimmunology 2014; 3:e28694; PMID:25097804; http://dx.doi.org/10.4161/onci.28694
-
(2014)
Oncoimmunology
, vol.3
, pp. 28694
-
-
Pol, J.1
Bloy, N.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Cremer, I.6
Erbs, P.7
Limacher, J.M.8
Preville, X.9
Zitvogel, L.10
-
111
-
-
84885720059
-
Trial watch: oncolytic viruses for cancer therapy
-
23894720
-
E.Vacchelli, A.Eggermont, C.Sautes-Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: oncolytic viruses for cancer therapy. Oncoimmunology 2013; 2:e24612; PMID:23894720; http://dx.doi.org/10.4161/onci.24612
-
(2013)
Oncoimmunology
, vol.2
, pp. 24612
-
-
Vacchelli, E.1
Eggermont, A.2
Sautes-Fridman, C.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
112
-
-
84897476768
-
Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
-
24598590
-
D.Zamarin, R.B.Holmgaard, S.K.Subudhi, J.S.Park, M.Mansour, P.Palese, T.Merghoub, J.D.Wolchok, J.P.Allison. Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy. Sci Transl Med 2014; 6:226ra32; PMID:24598590; http://dx.doi.org/10.1126/scitranslmed.3008095
-
(2014)
Sci Transl Med
, vol.6
, pp. 226
-
-
Zamarin, D.1
Holmgaard, R.B.2
Subudhi, S.K.3
Park, J.S.4
Mansour, M.5
Palese, P.6
Merghoub, T.7
Wolchok, J.D.8
Allison, J.P.9
-
113
-
-
84964313298
-
Bevacizumab plus ipilimumab in patients with metastatic melanoma
-
24838938
-
F.S.Hodi, D.Lawrence, C.Lezcano, X.Wu, J.Zhou, T.Sasada, W.Zeng, A.Giobbie-Hurder, M.B.Atkins, N.Ibrahim, Bevacizumab plus ipilimumab in patients with metastatic melanoma. Cancer Immunol Res 2014; 2:632-42; PMID:24838938; http://dx.doi.org/10.1158/2326-6066.CIR-14-0053
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 632-642
-
-
Hodi, F.S.1
Lawrence, D.2
Lezcano, C.3
Wu, X.4
Zhou, J.5
Sasada, T.6
Zeng, W.7
Giobbie-Hurder, A.8
Atkins, M.B.9
Ibrahim, N.10
-
114
-
-
84899115962
-
Trial watch: tumor-targeting monoclonal antibodies in cancer therapy
-
24605265
-
E.Vacchelli, F.Aranda, A.Eggermont, J.Galon, C.Sautes-Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: tumor-targeting monoclonal antibodies in cancer therapy. Oncoimmunology 2014; 3:e27048; PMID:24605265; http://dx.doi.org/10.4161/onci.27048
-
(2014)
Oncoimmunology
, vol.3
, pp. 27048
-
-
Vacchelli, E.1
Aranda, F.2
Eggermont, A.3
Galon, J.4
Sautes-Fridman, C.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
115
-
-
84938579374
-
A phase 1 (Ph1) trial of MK-3475 combined with lenalidomide (Len) and low-dose dexamethasone (Dex) in patients (pts) with relapsedrefractory multiple myeloma (RRMM)
-
D.S.D.Siegel, P.Moreau, D.Avigan, K.C.Anderson, D.E.Reece, J.San Miguel, A phase 1 (Ph1) trial of MK-3475 combined with lenalidomide (Len) and low-dose dexamethasone (Dex) in patients (pts) with relapsedrefractory multiple myeloma (RRMM). ASCO Meeting Abstr 2014; 32:TPS3117.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3117
-
-
Siegel, D.S.D.1
Moreau, P.2
Avigan, D.3
Anderson, K.C.4
Reece, D.E.5
San Miguel, J.6
-
116
-
-
84892409579
-
Trial watch: lenalidomide-based immunochemotherapy
-
24482747
-
M.Semeraro, E.Vacchelli, A.Eggermont, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: lenalidomide-based immunochemotherapy. Oncoimmunology 2013; 2:e26494; PMID:24482747; http://dx.doi.org/10.4161/onci.26494
-
(2013)
Oncoimmunology
, vol.2
, pp. 26494
-
-
Semeraro, M.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
117
-
-
84899051541
-
Novel insights into the mechanism of action of lenalidomide
-
25340011
-
M.Semeraro, L.Galluzzi. Novel insights into the mechanism of action of lenalidomide. Oncoimmunology 2014; 3:e28386; PMID:25340011; http://dx.doi.org/10.4161/onci.28386
-
(2014)
Oncoimmunology
, vol.3
, pp. 28386
-
-
Semeraro, M.1
Galluzzi, L.2
-
118
-
-
84914148032
-
Phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC)
-
H.J.Hammers, E.R.Plimack, J.R.Infante, M.S.Ernstoff, B.I.Rini, D.F.McDermott, Phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC). ASCO Meeting Abstr 2014; 32:4504.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 4504
-
-
Hammers, H.J.1
Plimack, E.R.2
Infante, J.R.3
Ernstoff, M.S.4
Rini, B.I.5
McDermott, D.F.6
-
119
-
-
84888340426
-
A phase I dose-escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) administered in combination with nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients (Pts) with advanced refractory solid tumors
-
R.E.Sanborn, W.H.Sharfman, N.H.Segal, F.S.Hodi, J.D.Wolchok, W.J.Urba, A phase I dose-escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) administered in combination with nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients (Pts) with advanced refractory solid tumors. ASCO Meeting Abstr 2013; 31:TPS3110.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 3110
-
-
Sanborn, R.E.1
Sharfman, W.H.2
Segal, N.H.3
Hodi, F.S.4
Wolchok, J.D.5
Urba, W.J.6
-
120
-
-
84907521154
-
A phase I dose escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) in combination with nivolumab (anti-PD-1; BMS-936558, ONO-4538) in advanced solid tumors
-
N.H.Segal, F.S.Hodi, R.E.Sanborn, T.Gajewski, J.D.Wolchok, W.J.Urba, A phase I dose escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) in combination with nivolumab (anti-PD-1; BMS-936558, ONO-4538) in advanced solid tumors. ASCO Meeting Abstr 2014; 32:TPS3115.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3115
-
-
Segal, N.H.1
Hodi, F.S.2
Sanborn, R.E.3
Gajewski, T.4
Wolchok, J.D.5
Urba, W.J.6
-
121
-
-
84886945638
-
Current trends of anticancer immunochemotherapy
-
23894726
-
E.Vacchelli, N.Prada, O.Kepp, L.Galluzzi. Current trends of anticancer immunochemotherapy. Oncoimmunology 2013; 2:e25396; PMID:23894726; http://dx.doi.org/10.4161/onci.25396
-
(2013)
Oncoimmunology
, vol.2
, pp. 25396
-
-
Vacchelli, E.1
Prada, N.2
Kepp, O.3
Galluzzi, L.4
-
122
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
24714771
-
J.M.Taube, A.Klein, J.R.Brahmer, H.Xu, X.Pan, J.H.Kim, L.Chen, D.M.Pardoll, S.L.Topalian, R.A.Anders. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 2014; 20:5064-74; PMID:24714771; http://dx.doi.org/10.1158/1078-0432.CCR-13-3271
-
(2014)
Clin Cancer Res
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
Xu, H.4
Pan, X.5
Kim, J.H.6
Chen, L.7
Pardoll, D.M.8
Topalian, S.L.9
Anders, R.A.10
-
123
-
-
84890280934
-
Identification of new prognostic biomarkers for Stage III metastatic melanoma patients
-
24228228
-
H.Kakavand, R.A.Scolyer, J.F.Thompson, G.J.Mann. Identification of new prognostic biomarkers for Stage III metastatic melanoma patients. Oncoimmunology 2013; 2:e25564; PMID:24228228; http://dx.doi.org/10.4161/onci.25564
-
(2013)
Oncoimmunology
, vol.2
, pp. 25564
-
-
Kakavand, H.1
Scolyer, R.A.2
Thompson, J.F.3
Mann, G.J.4
-
124
-
-
84902603313
-
Immune response markers in sentinel nodes may predict melanoma progression
-
25050216
-
M.Rodolfo, C.Castelli, L.Rivoltini. Immune response markers in sentinel nodes may predict melanoma progression. Oncoimmunology 2014; 3:e28498; PMID:25050216; http://dx.doi.org/10.4161/onci.28498
-
(2014)
Oncoimmunology
, vol.3
, pp. 28498
-
-
Rodolfo, M.1
Castelli, C.2
Rivoltini, L.3
-
126
-
-
85047692172
-
Therapeutic vaccines for cancer: an overview of clinical trials
-
25001465
-
I.Melero, G.Gaudernack, W.Gerritsen, C.Huber, G.Parmiani, S.Scholl, N.Thatcher, J.Wagstaff, C.Zielinski, I.Faulkner, Therapeutic vaccines for cancer: an overview of clinical trials. Nat Rev Clin Oncol 2014; 11:509-24; PMID:25001465; http://dx.doi.org/10.1038/nrclinonc.2014.111
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 509-524
-
-
Melero, I.1
Gaudernack, G.2
Gerritsen, W.3
Huber, C.4
Parmiani, G.5
Scholl, S.6
Thatcher, N.7
Wagstaff, J.8
Zielinski, C.9
Faulkner, I.10
-
127
-
-
84875535374
-
Trial watch: prognostic and predictive value of the immune infiltrate in cancer
-
23243596
-
L.Senovilla, E.Vacchelli, J.Galon, S.Adjemian, A.Eggermont, W.H.Fridman, C.Sautès-Fridman, Y.Ma, E.Tartour, L.Zitvogel, Trial watch: prognostic and predictive value of the immune infiltrate in cancer. Oncoimmunology 2012; 1:1323-43; PMID:23243596; http://dx.doi.org/10.4161/onci.22009
-
(2012)
Oncoimmunology
, vol.1
, pp. 1323-1343
-
-
Senovilla, L.1
Vacchelli, E.2
Galon, J.3
Adjemian, S.4
Eggermont, A.5
Fridman, W.H.6
Sautès-Fridman, C.7
Ma, Y.8
Tartour, E.9
Zitvogel, L.10
-
128
-
-
84885840329
-
Immune correlates of melanoma survival in adoptive cell therapy
-
23525606
-
A.F.Lee, P.A.Sieling, D.J.Lee. Immune correlates of melanoma survival in adoptive cell therapy. Oncoimmunology 2013; 2:e22889; PMID:23525606; http://dx.doi.org/10.4161/onci.22889
-
(2013)
Oncoimmunology
, vol.2
, pp. 22889
-
-
Lee, A.F.1
Sieling, P.A.2
Lee, D.J.3
-
129
-
-
84922097884
-
Evaluation of immune-related response criteria (irRC) in patients (pts) with advanced melanoma (MEL) treated with the anti-PD-1 monoclonal antibody MK-3475
-
F.S.Hodi, A.Ribas, A.Daud, O.Hamid, C.Robert, R.Kefford, Evaluation of immune-related response criteria (irRC) in patients (pts) with advanced melanoma (MEL) treated with the anti-PD-1 monoclonal antibody MK-3475. ASCO Meeting Abstr 2014; 32:3006.
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 3006
-
-
Hodi, F.S.1
Ribas, A.2
Daud, A.3
Hamid, O.4
Robert, C.5
Kefford, R.6
-
130
-
-
80455173518
-
Hemophilia A induced by ipilimumab
-
22047582
-
J.Delyon, C.Mateus, T.Lambert. Hemophilia A induced by ipilimumab. N Engl J Med 2011; 365:1747-8; PMID:22047582; http://dx.doi.org/10.1056/NEJMc1110923
-
(2011)
N Engl J Med
, vol.365
, pp. 1747-1748
-
-
Delyon, J.1
Mateus, C.2
Lambert, T.3
-
131
-
-
67650491041
-
Anti-CTLA4 antibody-induced lupus nephritis
-
19587352
-
F.Fadel, El K.Karoui, B.Knebelmann. Anti-CTLA4 antibody-induced lupus nephritis. N Engl J Med 2009; 361:211-2; PMID:19587352; http://dx.doi.org/10.1056/NEJMc0904283
-
(2009)
N Engl J Med
, vol.361
, pp. 211-212
-
-
Fadel, F.1
Karoui, K.2
Knebelmann, B.3
-
132
-
-
84875785905
-
Hepatotoxicity with combination of vemurafenib and ipilimumab
-
23550685
-
A.Ribas, F.S.Hodi, M.Callahan, C.Konto, J.Wolchok. Hepatotoxicity with combination of vemurafenib and ipilimumab. N Engl J Med 2013; 368:1365-6; PMID:23550685; http://dx.doi.org/10.1056/NEJMc1302338
-
(2013)
N Engl J Med
, vol.368
, pp. 1365-1366
-
-
Ribas, A.1
Hodi, F.S.2
Callahan, M.3
Konto, C.4
Wolchok, J.5
-
133
-
-
84890281406
-
Adverse events to monoclonal antibodies used for cancer therapy: focus on hypersensitivity responses
-
24251081
-
B.A.Baldo. Adverse events to monoclonal antibodies used for cancer therapy: focus on hypersensitivity responses. Oncoimmunology 2013; 2:e26333; PMID:24251081; http://dx.doi.org/10.4161/onci.26333
-
(2013)
Oncoimmunology
, vol.2
, pp. 26333
-
-
Baldo, B.A.1
|