-
1
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000;60: 7075-83.
-
(2000)
Cancer Res
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
-
2
-
-
0035107383
-
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer
-
Ivanov S, Liao SY, Ivanova A, Danilkovitch-Miagkova A, Tarasova N, Weirich G, et al. Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol 2001;158: 905-19.
-
(2001)
Am J Pathol
, vol.158
, pp. 905-919
-
-
Ivanov, S.1
Liao, S.Y.2
Ivanova, A.3
Danilkovitch-Miagkova, A.4
Tarasova, N.5
Weirich, G.6
-
3
-
-
44849142755
-
Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer
-
Barnett DH, Sheng S, Charn TH, Waheed A, Sly WS, Lin CY, et al. Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer. Cancer Res 2008;68: 3505-15.
-
(2008)
Cancer Res
, vol.68
, pp. 3505-3515
-
-
Barnett, D.H.1
Sheng, S.2
Charn, T.H.3
Waheed, A.4
Sly, W.S.5
Lin, C.Y.6
-
4
-
-
0033637648
-
Expression of the membrane-associated carbonic anhydrase isozyme XII in the human kidney and renal tumors
-
Parkkila S, Parkkila AK, Saarnio J, Kivela J, Karttunen TJ, Kaunisto K, et al. Expression of the membrane-associated carbonic anhydrase isozyme XII in the human kidney and renal tumors. J Histochem Cytochem 2000;48: 1601-8.
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 1601-1608
-
-
Parkkila, S.1
Parkkila, A.K.2
Saarnio, J.3
Kivela, J.4
Karttunen, T.J.5
Kaunisto, K.6
-
5
-
-
0033775150
-
Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours
-
Kivela AJ, Parkkila S, Saarnio J, Karttunen TJ, Kivela J, Parkkila AK, et al. Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours. Histochem Cell Biol 2000;114: 197-204.
-
(2000)
Histochem Cell Biol
, vol.114
, pp. 197-204
-
-
Kivela, A.J.1
Parkkila, S.2
Saarnio, J.3
Karttunen, T.J.4
Kivela, J.5
Parkkila, A.K.6
-
6
-
-
0033902802
-
Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors
-
Kivela A, Parkkila S, Saarnio J, Karttunen TJ, Kivela J, Parkkila AK, et al. Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors. Am J Pathol 2000;156: 577-84.
-
(2000)
Am J Pathol
, vol.156
, pp. 577-584
-
-
Kivela, A.1
Parkkila, S.2
Saarnio, J.3
Karttunen, T.J.4
Kivela, J.5
Parkkila, A.K.6
-
7
-
-
84860001243
-
Tumorassociated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis
-
Chien MH, Ying TH, Hsieh YH, Lin CH, Shih CH, Wei LH, et al. Tumorassociated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis. Oral Oncol 2012;48: 417-23.
-
(2012)
Oral Oncol
, vol.48
, pp. 417-423
-
-
Chien, M.H.1
Ying, T.H.2
Hsieh, Y.H.3
Lin, C.H.4
Shih, C.H.5
Wei, L.H.6
-
8
-
-
27644554067
-
Expression of hypoxia-inducible carbonic anhydrases in brain tumors
-
Proescholdt MA, Mayer C, Kubitza M, Schubert T, Liao SY, Stanbridge EJ, et al. Expression of hypoxia-inducible carbonic anhydrases in brain tumors. Neuro Oncol 2005;7: 465-75.
-
(2005)
Neuro Oncol
, vol.7
, pp. 465-475
-
-
Proescholdt, M.A.1
Mayer, C.2
Kubitza, M.3
Schubert, T.4
Liao, S.Y.5
Stanbridge, E.J.6
-
9
-
-
78649656359
-
Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis
-
Ilie MI, Hofman V, Ortholan C, Ammadi RE, Bonnetaud C, Havet K, et al. Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis. Int J Cancer 2011;128: 1614-23.
-
(2011)
Int J Cancer
, vol.128
, pp. 1614-1623
-
-
Ilie, M.I.1
Hofman, V.2
Ortholan, C.3
Ammadi, R.E.4
Bonnetaud, C.5
Havet, K.6
-
10
-
-
33845515875
-
Expression of transmembrane carbonic anhydrases IX and XII in ovarian tumours
-
Hynninen P, Vaskivuo L, Saarnio J, Haapasalo H, Kivela J, Pastorekova S, et al. Expression of transmembrane carbonic anhydrases IX and XII in ovarian tumours. Histopathology 2006;49: 594-602.
-
(2006)
Histopathology
, vol.49
, pp. 594-602
-
-
Hynninen, P.1
Vaskivuo, L.2
Saarnio, J.3
Haapasalo, H.4
Kivela, J.5
Pastorekova, S.6
-
11
-
-
84855676598
-
Carbonic anhydrase isozymes II, IX, and XII in uterine tumors
-
Hynninen P, Parkkila S, Huhtala H, Pastorekova S, Pastorek J, Waheed A, et al. Carbonic anhydrase isozymes II, IX, and XII in uterine tumors. APMIS 2012;120: 117-29.
-
(2012)
APMIS
, vol.120
, pp. 117-129
-
-
Hynninen, P.1
Parkkila, S.2
Huhtala, H.3
Pastorekova, S.4
Pastorek, J.5
Waheed, A.6
-
12
-
-
6744255826
-
Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium
-
Karhumaa P, Parkkila S, Tureci O, Waheed A, Grubb JH, Shah G, et al. Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium. Mol Human Reprod 2000;6: 68-74.
-
(2000)
Mol Human Reprod
, vol.6
, pp. 68-74
-
-
Karhumaa, P.1
Parkkila, S.2
Tureci, O.3
Waheed, A.4
Grubb, J.H.5
Shah, G.6
-
13
-
-
0037374846
-
Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: Overexpression of CA12 (CAXII) in glaucoma
-
Liao SY, Ivanov S, Ivanova A, Ghosh S, Cote MA, Keefe K, et al. Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma. J Med Genet 2003;40: 257-61.
-
(2003)
J Med Genet
, vol.40
, pp. 257-261
-
-
Liao, S.Y.1
Ivanov, S.2
Ivanova, A.3
Ghosh, S.4
Cote, M.A.5
Keefe, K.6
-
14
-
-
77953550229
-
Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study
-
Oksala N, Levula M, Pelto-Huikko M, Kytomaki L, Soini JT, Salenius J, et al. Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study. Ann Med 2010;42: 360-70.
-
(2010)
Ann Med
, vol.42
, pp. 360-370
-
-
Oksala, N.1
Levula, M.2
Pelto-Huikko, M.3
Kytomaki, L.4
Soini, J.T.5
Salenius, J.6
-
15
-
-
84863405507
-
CAXII Is a sero-diagnostic marker for lung cancer
-
Kobayashi M, Matsumoto T, Ryuge S, Yanagita K, Nagashio R, Kawakami Y, et al. CAXII Is a sero-diagnostic marker for lung cancer. PLoS ONE 2012;7:e33952.
-
(2012)
PLoS ONE
, vol.7
-
-
Kobayashi, M.1
Matsumoto, T.2
Ryuge, S.3
Yanagita, K.4
Nagashio, R.5
Kawakami, Y.6
-
16
-
-
84855431961
-
Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes
-
Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Lopez AS, et al. Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes. Clin Cancer Res 2012;18: 207-19.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 207-219
-
-
Tafreshi, N.K.1
Bui, M.M.2
Bishop, K.3
Lloyd, M.C.4
Enkemann, S.A.5
Lopez, A.S.6
-
17
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, et al. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 2009;69: 358-68.
-
(2009)
Cancer Res
, vol.69
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
Trottier, E.4
Dayan, F.5
Mazure, N.M.6
-
18
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008;7: 1-14.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1-14
-
-
Supuran, C.T.1
-
20
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 1989;49: 6449-65.
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
21
-
-
67749145635
-
The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths
-
Swietach P, Patiar S, Supuran CT, Harris AL, Vaughan-Jones RD. The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths. J Biol Chem 2009;284: 20299-310.
-
(2009)
J Biol Chem
, vol.284
, pp. 20299-20310
-
-
Swietach, P.1
Patiar, S.2
Supuran, C.T.3
Harris, A.L.4
Vaughan-Jones, R.D.5
-
22
-
-
50649105780
-
Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths
-
Swietach P, Wigfield S, Cobden P, Supuran CT, Harris AL, Vaughan- Jones RD. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. J Biol Chem 2008;283: 20473-83.
-
(2008)
J Biol Chem
, vol.283
, pp. 20473-20483
-
-
Swietach, P.1
Wigfield, S.2
Cobden, P.3
Supuran, C.T.4
Harris, A.L.5
Vaughan- Jones, R.D.6
-
23
-
-
79954600753
-
Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths
-
Hulikova A, Vaughan-Jones RD, Swietach P. Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths. J Biol Chem 2011;286: 13815-26.
-
(2011)
J Biol Chem
, vol.286
, pp. 13815-13826
-
-
Hulikova, A.1
Vaughan-Jones, R.D.2
Swietach, P.3
-
24
-
-
34547793020
-
Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters
-
Morgan PE, Pastorekova S, Stuart-Tilley AK, Alper SL, Casey JR. Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters. Am J Physiol Cell Physiol 2007;293: C738-48.
-
(2007)
Am J Physiol Cell Physiol
, vol.293
-
-
Morgan, P.E.1
Pastorekova, S.2
Stuart-Tilley, A.K.3
Alper, S.L.4
Casey, J.R.5
-
25
-
-
84862757952
-
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work
-
Gillies RJ, Verduzco D, Gatenby RA. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat Rev Cancer 2012;12: 487-93.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 487-493
-
-
Gillies, R.J.1
Verduzco, D.2
Gatenby, R.A.3
-
26
-
-
84874886049
-
Acidity generated by the tumor microenvironment drives local invasion
-
Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim- Hashim A, et al. Acidity generated by the tumor microenvironment drives local invasion. Cancer Res 2013;73: 1524-35.
-
(2013)
Cancer Res
, vol.73
, pp. 1524-1535
-
-
Estrella, V.1
Chen, T.2
Lloyd, M.3
Wojtkowiak, J.4
Cornnell, H.H.5
Ibrahim- Hashim, A.6
-
27
-
-
33744942376
-
Acidmediated tumor invasion: A multidisciplinary study
-
Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ. Acidmediated tumor invasion: a multidisciplinary study. Cancer Res 2006; 66: 5216-23.
-
(2006)
Cancer Res
, vol.66
, pp. 5216-5223
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
Gmitro, A.F.3
Kaylor, B.4
Gillies, R.J.5
-
28
-
-
84861762712
-
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy
-
McIntyre A, Patiar S,Wigfield S, Li JL, Ledaki I, Turley H, et al. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clin Cancer Res 2012;18: 3100-11.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3100-3111
-
-
McIntyre, A.1
Patiar Swigfield, S.2
Li, J.L.3
Ledaki, I.4
Turley, H.5
-
29
-
-
77953028343
-
Carbonic anhydrase XII promotes invasion and migration ability ofMDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway
-
Hsieh MJ, Chen KS, Chiou HL, Hsieh YS. Carbonic anhydrase XII promotes invasion and migration ability ofMDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway. Eur J Cell Biol 2010; 89: 598-606.
-
(2010)
Eur J Cell Biol
, vol.89
, pp. 598-606
-
-
Hsieh, M.J.1
Chen, K.S.2
Chiou, H.L.3
Hsieh, Y.S.4
-
30
-
-
79960359073
-
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
-
Dubois L, Peeters S, Lieuwes NG, Geusens N, Thiry A, Wigfield S, et al. Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation. Radiother Oncol 2011;99: 424-31.
-
(2011)
Radiother Oncol
, vol.99
, pp. 424-431
-
-
Dubois, L.1
Peeters, S.2
Lieuwes, N.G.3
Geusens, N.4
Thiry, A.5
Wigfield, S.6
-
31
-
-
79955549517
-
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII
-
Battke C, Kremmer E, Mysliwietz J, Gondi G, Dumitru C, Brandau S, et al. Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII. Cancer Immunol Immunother 2011;60: 649-58.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 649-658
-
-
Battke, C.1
Kremmer, E.2
Mysliwietz, J.3
Gondi, G.4
Dumitru, C.5
Brandau, S.6
-
32
-
-
79955548092
-
Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC
-
Battke C, Ruiss R, Welsch U, Wimberger P, Lang S, Jochum S, et al. Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC. Cancer Immunol Immunother 2011;60: 639-48.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 639-648
-
-
Battke, C.1
Ruiss, R.2
Welsch, U.3
Wimberger, P.4
Lang, S.5
Jochum, S.6
-
33
-
-
84871730188
-
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing inmice
-
Terziyska N, Castro Alves C, Groiss V, Schneider K, Farkasova K, Ogris M, et al. In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing inmice. PLoS ONE 2012;7: e52798.
-
(2012)
PLoS ONE
, vol.7
-
-
Terziyska, N.1
Castro Alves, C.2
Groiss, V.3
Schneider, K.4
Farkasova, K.5
Ogris, M.6
-
34
-
-
79952488307
-
Antibody inhibiting enzymatic activity of tumourassociated carbonic anhydrase isoform IX
-
Murri-Plesko MT, Hulikova A, Oosterwijk E, Scott AM, Zortea A, Harris AL, et al. Antibody inhibiting enzymatic activity of tumourassociated carbonic anhydrase isoform IX. Eur J Pharmacol 2011;657: 173-83.
-
(2011)
Eur J Pharmacol
, vol.657
, pp. 173-183
-
-
Murri-Plesko, M.T.1
Hulikova, A.2
Oosterwijk, E.3
Scott, A.M.4
Zortea, A.5
Harris, A.L.6
-
35
-
-
0034687801
-
Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers
-
Ulmasov B, Waheed A, Shah G, Grubb J, Sly W, Tu C, et al. Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers. Proc Natl Acad Sci U S A 2000;97: 14212-7.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14212-14217
-
-
Ulmasov, B.1
Waheed, A.2
Shah, G.3
Grubb, J.4
Sly, W.5
Tu, C.6
-
36
-
-
0025899234
-
Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
-
Cory A, Owen T, Barltrop J, Cory J. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 1991;3: 207-12.
-
(1991)
Cancer Commun
, vol.3
, pp. 207-212
-
-
Cory, A.1
Owen, T.2
Barltrop, J.3
Cory, J.4
-
37
-
-
18344410760
-
NOD/SCID/gamma(c)(null) mouse: An excellent recipient mouse model for engraftment of human cells
-
Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K, et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood 2002;100: 3175-82.
-
(2002)
Blood
, vol.100
, pp. 3175-3182
-
-
Ito, M.1
Hiramatsu, H.2
Kobayashi, K.3
Suzue, K.4
Kawahata, M.5
Hioki, K.6
-
38
-
-
84869009687
-
How cancer metabolism is tuned for proliferation and vulnerable to disruption
-
Schulze A, Harris A. How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature 2012;491: 364-73.
-
(2012)
Nature
, vol.491
, pp. 364-373
-
-
Schulze, A.1
Harris, A.2
-
39
-
-
0041563839
-
Carbonic anhydrase isozymes IX and XII in gastric tumors
-
Leppilampi M, Saarnio J, Karttunen T, Kivela J, Pastorekova S, Pastorek J, et al. Carbonic anhydrase isozymes IX and XII in gastric tumors. World J Gastroenterol 2003;9: 1398-403.
-
(2003)
World J Gastroenterol
, vol.9
, pp. 1398-1403
-
-
Leppilampi, M.1
Saarnio, J.2
Karttunen, T.3
Kivela, J.4
Pastorekova, S.5
Pastorek, J.6
-
40
-
-
0035105565
-
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
-
Wykoff C, Beasley N, Watson P, Campo L, Chia S, English R, et al. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol 2001;158: 1011-9.
-
(2001)
Am J Pathol
, vol.158
, pp. 1011-1019
-
-
Wykoff, C.1
Beasley, N.2
Watson, P.3
Campo, L.4
Chia, S.5
English, R.6
|