메뉴 건너뛰기




Volumn 9, Issue , 2015, Pages

Why does obesity promote cancer? Epidemiology, biology, and open questions

Author keywords

Body mass index; DNA damage; Inflammation; Insulin; Obesity

Indexed keywords

ESTROGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; METFORMIN; SOMATOMEDIN C;

EID: 84938685746     PISSN: None     EISSN: 17546605     Source Type: Journal    
DOI: 10.3332/ecancer.2015.554     Document Type: Review
Times cited : (28)

References (109)
  • 1
    • 84896690513 scopus 로고    scopus 로고
    • Prevalence of childhood and adult obesity in the United States, 2011-2012
    • PMID: 24570244
    • Ogden CL et al (2014) Prevalence of childhood and adult obesity in the United States, 2011-2012 JAMA 311(8) 806-14 DOI: 10.1001/jama.2014.732 PMID: 24570244
    • (2014) JAMA , vol.311 , Issue.8 , pp. 806-814
    • Ogden, C.L.1
  • 2
    • 83255181794 scopus 로고    scopus 로고
    • The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010
    • Parkin DM, Boyd L and Walker LC (2011) The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010 Br J Cancer 105(Suppl 2) S77-S81 DOI: 10.1038/bjc.2011.489
    • (2011) Br J Cancer , vol.105 , pp. S77-S81
    • Parkin, D.M.1    Boyd, L.2    Walker, L.C.3
  • 3
    • 84924910144 scopus 로고    scopus 로고
    • Global burden of cancer attributable to high body-mass index in 2012: A population-based study
    • Arnold M et al (2015) Global burden of cancer attributable to high body-mass index in 2012: a population-based study Lancet Oncol 16(1) 36-46 DOI: 10.1016/s1470-2045(14)71123-4
    • (2015) Lancet Oncol , vol.16 , Issue.1 , pp. 36-46
    • Arnold, M.1
  • 4
    • 0001540069 scopus 로고
    • Obesity and the time of appearance of spontaneous mammary carcinoma in C3H mice
    • PMID: 13042818
    • Waxler SH et al (1953) Obesity and the time of appearance of spontaneous mammary carcinoma in C3H mice Cancer Res 13(3) 276-8 PMID: 13042818
    • (1953) Cancer Res , vol.13 , Issue.3 , pp. 276-278
    • Waxler, S.H.1
  • 5
    • 0013908917 scopus 로고
    • Augmentation of mammary tumors in castrated obese C3H Mice
    • PMID: 5934796
    • Waxler SH and Leef MF (1966) Augmentation of mammary tumors in castrated obese C3H Mice Cancer Res 26(5) 860-2 PMID: 5934796
    • (1966) Cancer Res , vol.26 , Issue.5 , pp. 860-862
    • Waxler, S.H.1    Leef, M.F.2
  • 6
    • 0000700437 scopus 로고
    • The bimodal age distribution of patients with mammary carcinoma. Evidence for the existence of 2 types of human breast cancer
    • PMID: 14123673
    • de Waard F, Halewijn EABV and Huizinga J (1964) The bimodal age distribution of patients with mammary carcinoma. Evidence for the existence of 2 types of human breast cancer Cancer 17 141-51 DOI: 10.1002/1097-0142(196402)17:2<141::AID-CNCR2820170202>3.0.CO;2-Z PMID: 14123673
    • (1964) Cancer , vol.17 , pp. 141-151
    • De Waard, F.1    Halewijn, E.A.B.V.2    Huizinga, J.3
  • 7
    • 85027951435 scopus 로고    scopus 로고
    • Body-mass index and risk of 22 specific cancers: A population-based cohort study of 5.24 million UK adults
    • PMID: 25129328 PMCID: 4151483
    • Bhaskaran K et al Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults Lancet 384(9945) 755-65 DOI: 10.1016/s0140-6736(14)60892-8 PMID: 25129328 PMCID: 4151483
    • Lancet , vol.384 , Issue.9945 , pp. 755-765
    • Bhaskaran, K.1
  • 8
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and nortality from cancer in a prospectively studied cohort of U.S. adults
    • PMID: 12711737
    • Calle EE et al (2003) Overweight, obesity, and nortality from cancer in a prospectively studied cohort of U.S. adults New Engl J Med 348(17) 1625-38 DOI: 10.1056/NEJMoa021423 PMID: 12711737
    • (2003) New Engl J Med , vol.348 , Issue.17 , pp. 1625-1638
    • Calle, E.E.1
  • 9
    • 17144385790 scopus 로고    scopus 로고
    • Excess deaths associated with underweight, overweight, and obesity
    • PMID: 15840860
    • Flegal KM et al (2005) Excess deaths associated with underweight, overweight, and obesity JAMA 293(15) 1861-7 DOI: 10.1001/jama.293.15.1861 PMID: 15840860
    • (2005) JAMA , vol.293 , Issue.15 , pp. 1861-1867
    • Flegal, K.M.1
  • 10
    • 0036798987 scopus 로고    scopus 로고
    • Obesity, body size, and risk of postmenopausal breast cancer: The Women's Health Initiative (United States)
    • PMID: 12420953
    • Morimoto LM et al (2002) Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States) Cancer Causes Control 13(8) 741-51 DOI: 10.1023/A:1020239211145 PMID: 12420953
    • (2002) Cancer Causes Control , vol.13 , Issue.8 , pp. 741-751
    • Morimoto, L.M.1
  • 11
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies
    • PMID: 18280327
    • Renehan AG et al (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies Lancet 371(9612) 569-78 DOI: 10.1016/S0140-6736(08)60269-X PMID: 18280327
    • (2008) Lancet , vol.371 , Issue.9612 , pp. 569-578
    • Renehan, A.G.1
  • 12
    • 84860813556 scopus 로고    scopus 로고
    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: A large prospective cohort study
    • PMID: 22583394 PMCID: 3446339
    • Ritte R et al (2012) Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study Breast Cancer Res 14(3) R76 DOI: 10.1186/bcr3186 PMID: 22583394 PMCID: 3446339
    • (2012) Breast Cancer Res , vol.14 , Issue.3 , pp. R76
    • Ritte, R.1
  • 13
    • 34047262341 scopus 로고    scopus 로고
    • Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP diet and health study cohort
    • PMID: 17374835
    • Thiebaut AC et al (2007) Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP diet and health study cohort J Natl Cancer Inst 99 451-62 DOI: 10.1093/jnci/djk094 PMID: 17374835
    • (2007) J Natl Cancer Inst , vol.99 , pp. 451-462
    • Thiebaut, A.C.1
  • 14
    • 47249093665 scopus 로고    scopus 로고
    • Accuracy of body mass index to diagnose obesity in the US adult population
    • Romero-Corral A et al (2008) Accuracy of body mass index to diagnose obesity in the US adult population Intl J Obes (2005) 32(6) 959-66 DOI: 10.1038/ijo.2008.11
    • (2008) Intl J Obes (2005) , vol.32 , Issue.6 , pp. 959-966
    • Romero-Corral, A.1
  • 16
    • 84855577993 scopus 로고    scopus 로고
    • Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols
    • Breccia M et al (2012) Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols Blood 119(1) 49-54 DOI: 10.1182/blood-2011-07-369595
    • (2012) Blood , vol.119 , Issue.1 , pp. 49-54
    • Breccia, M.1
  • 17
    • 62849107573 scopus 로고    scopus 로고
    • Body-mass index and cause-specific mortality in 900 000 adults: Collaborative analyses of 57 prospective studies
    • PMID: 19299006 PMCID: 2662372
    • Whitlock G et al (2009) Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies Lancet 373(9669) 1083-1096 DOI: 10.1016/S0140-6736(09)60318-4 PMID: 19299006 PMCID: 2662372
    • (2009) Lancet , vol.373 , Issue.9669 , pp. 1083-1096
    • Whitlock, G.1
  • 18
    • 84907597890 scopus 로고    scopus 로고
    • Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies
    • PMID: 24769692 PMCID: 4176449
    • Chan DS et al (2014) Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies Ann Oncol 25(10) 1901-14 DOI: 10.1093/annonc/mdu042 PMID: 24769692 PMCID: 4176449
    • (2014) Ann Oncol , vol.25 , Issue.10 , pp. 1901-1914
    • Chan, D.S.1
  • 19
    • 84894040966 scopus 로고    scopus 로고
    • How accurate is self-reported BMI?
    • Gosse MA (2014) How accurate is self-reported BMI? Nutr Bulletin 39 105-114 DOI: 10.1111/nbu.12075
    • (2014) Nutr Bulletin , vol.39 , pp. 105-114
    • Gosse, M.A.1
  • 20
    • 58149306378 scopus 로고    scopus 로고
    • Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status - A meta-analysis
    • Suzuki R et al (2009) Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status - a meta-analysis Int J Cancer 124(3) 698-712 DOI: 10.1002/ijc.23943
    • (2009) Int J Cancer , vol.124 , Issue.3 , pp. 698-712
    • Suzuki, R.1
  • 21
    • 0029882353 scopus 로고    scopus 로고
    • Reversal of relation between body mass and endogenous estrogen concentrations with menopausal status
    • PMID: 8637031
    • Potischman N (1996) Reversal of relation between body mass and endogenous estrogen concentrations with menopausal status J Natl Cancer Inst 88(11) 756-8 DOI: 10.1093/jnci/88.11.756 PMID: 8637031
    • (1996) J Natl Cancer Inst , vol.88 , Issue.11 , pp. 756-758
    • Potischman, N.1
  • 22
    • 84883055606 scopus 로고    scopus 로고
    • Sex hormones and risk of breast cancer in premenopausal women: A collaborative reanalysis of individual participant data from seven prospective studies
    • PMID: 23890780 PMCID: 4056766
    • Key TJ (2013) Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies Lancet Oncol 14(10) 1009-19 DOI: 10.1016/S1470-2045(13)70301-2 PMID: 23890780 PMCID: 4056766
    • (2013) Lancet Oncol , vol.14 , Issue.10 , pp. 1009-1019
    • Key, T.J.1
  • 23
    • 79251513206 scopus 로고    scopus 로고
    • Effect of Obesity on Prognosis After Early-Stage Breast Cancer
    • PMID: 21115856
    • Ewertz M et al (2010) Effect of Obesity on Prognosis After Early-Stage Breast Cancer J Clin Oncol 29(1) 25-31 DOI: 10.1200/JCO.2010.29.7614 PMID: 21115856
    • (2010) J Clin Oncol , vol.29 , Issue.1 , pp. 25-31
    • Ewertz, M.1
  • 24
    • 79960128817 scopus 로고    scopus 로고
    • Impact of body mass index on the efficacy of endocrine therapy in premenopausal patients with breast cancer: An analysis of the prospective ABCSG-12 trial
    • PMID: 21555684
    • Pfeiler G et al (2011) Impact of body mass index on the efficacy of endocrine therapy in premenopausal patients with breast cancer: an analysis of the prospective ABCSG-12 trial J Clin Oncol 29(19) 2653-9 DOI: 10.1200/JCO.2010.33.2585 PMID: 21555684
    • (2011) J Clin Oncol , vol.29 , Issue.19 , pp. 2653-2659
    • Pfeiler, G.1
  • 25
    • 77955296639 scopus 로고    scopus 로고
    • Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: An exploratory analysis from the ATAC trial
    • PMID: 20547990
    • Sestak I et al (2010) Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial J Clin Oncol 28(21) 3411-5 DOI: 10.1200/JCO.2009.27.2021 PMID: 20547990
    • (2010) J Clin Oncol , vol.28 , Issue.21 , pp. 3411-3415
    • Sestak, I.1
  • 26
    • 84886791716 scopus 로고    scopus 로고
    • Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients
    • PMID: 23953055
    • Mazzarella L et al (2013) Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients Eur J Cancer 49(17) 3588-97 DOI: 10.1016/j.ejca.2013.07.016 PMID: 23953055
    • (2013) Eur J Cancer , vol.49 , Issue.17 , pp. 3588-3597
    • Mazzarella, L.1
  • 27
    • 84866747124 scopus 로고    scopus 로고
    • A systematic review of the impact of weight loss on cancer incidence and mortality
    • PMID: 22672203
    • Birks S et al (2012) A systematic review of the impact of weight loss on cancer incidence and mortality Obes Rev 13(10) 868-91 DOI: 10.1111/j.1467-789X.2012.01010.x PMID: 22672203
    • (2012) Obes Rev , vol.13 , Issue.10 , pp. 868-891
    • Birks, S.1
  • 28
    • 33745774113 scopus 로고    scopus 로고
    • Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    • PMID: 16818856
    • Pischon T et al (2006) Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC) J Natl Cancer Inst 98(13) 920-31 DOI: 10.1093/jnci/djj246 PMID: 16818856
    • (2006) J Natl Cancer Inst , vol.98 , Issue.13 , pp. 920-931
    • Pischon, T.1
  • 29
    • 84891412786 scopus 로고    scopus 로고
    • Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANA-CEA study
    • Steins Bisschop CN et al (2014) Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANA-CEA study Am J Clin Nutr 99(1) 139-147 DOI: 10.3945/ajcn.113.066530
    • (2014) Am J Clin Nutr , vol.99 , Issue.1 , pp. 139-147
    • Steins Bisschop, C.N.1
  • 30
    • 84899108371 scopus 로고    scopus 로고
    • Excess adiposity and survival in patients with colorectal cancer: A systematic review
    • PMID: 24433336
    • Parkin E et al (2014) Excess adiposity and survival in patients with colorectal cancer: a systematic review Obes Rev 15(5) 434-51 DOI: 10.1111/obr.12140 PMID: 24433336
    • (2014) Obes Rev , vol.15 , Issue.5 , pp. 434-451
    • Parkin, E.1
  • 31
    • 84911963851 scopus 로고    scopus 로고
    • Association of obesity and overweight with overall survival in colorectal cancer patients: A meta-analysis of 29 studies
    • PMID: 25070668
    • Wu S et al (2014) Association of obesity and overweight with overall survival in colorectal cancer patients: a meta-analysis of 29 studies Cancer Causes Control 25(11) 1489-1502 DOI: 10.1007/s10552-014-0450-y PMID: 25070668
    • (2014) Cancer Causes Control , vol.25 , Issue.11 , pp. 1489-1502
    • Wu, S.1
  • 32
    • 78650363503 scopus 로고    scopus 로고
    • Body mass index, hormone replacement therapy, and endometrial cancer risk: A meta-analysis
    • PMID: 21030602
    • Crosbie EJ et al (2010) Body mass index, hormone replacement therapy, and endometrial cancer risk: a meta-analysis Cancer Epidemiol Biomarkers Prev 19(12) 3119-30 DOI: 10.1158/1055-9965.EPI-10-0832 PMID: 21030602
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , Issue.12 , pp. 3119-3130
    • Crosbie, E.J.1
  • 33
    • 0014265362 scopus 로고
    • Glucose tolerance and endometrial carcinoma: A controlled study
    • PMID: 4868282
    • Dunn LJ et al (1968) Glucose tolerance and endometrial carcinoma: A controlled study Arch Intern Med 121(3) 246-54 DOI: 10.1001/archinte.1968.03640030038006 PMID: 4868282
    • (1968) Arch Intern Med , vol.121 , Issue.3 , pp. 246-254
    • Dunn, L.J.1
  • 34
    • 84909997906 scopus 로고    scopus 로고
    • Association between diabetes, diabetes treatment and risk of developing endometrial cancer
    • PMID: 25051408 PMCID: 4183842
    • Luo J et al (2014) Association between diabetes, diabetes treatment and risk of developing endometrial cancer Br J Cancer 111(7) 1432-9 DOI: 10.1038/bjc.2014.407 PMID: 25051408 PMCID: 4183842
    • (2014) Br J Cancer , vol.111 , Issue.7 , pp. 1432-1439
    • Luo, J.1
  • 35
    • 84877577954 scopus 로고    scopus 로고
    • Obesity and endometrial cancer survival: A systematic review
    • Arem H and Irwin ML (2013) Obesity and endometrial cancer survival: a systematic review Int J Obes (Lond) 37(5) 634-9 DOI: 10.1038/ijo.2012.94
    • (2013) Int J Obes (Lond) , vol.37 , Issue.5 , pp. 634-639
    • Arem, H.1    Irwin, M.L.2
  • 36
    • 84872834858 scopus 로고    scopus 로고
    • Body mass index, physical activity, and survival after endometrial cancer diagnosis: Results from the Women's Health Initiative
    • PMCID: 3552067
    • Arem H et al (2013) Body mass index, physical activity, and survival after endometrial cancer diagnosis: results from the Women's Health Initiative Gynecol Oncol 128(2) 181-6 DOI: 10.1016/j.ygyno.2012.10.029 PMCID: 3552067
    • (2013) Gynecol Oncol , vol.128 , Issue.2 , pp. 181-186
    • Arem, H.1
  • 37
    • 84874887864 scopus 로고    scopus 로고
    • Prediagnosis body mass index, physical activity, and mortality in endometrial cancer patients
    • PMID: 23297041 PMCID: 3589256
    • Arem H et al (2013) Prediagnosis body mass index, physical activity, and mortality in endometrial cancer patients J Natl Cancer Inst 105(5) 342-9 DOI: 10.1093/jnci/djs530 PMID: 23297041 PMCID: 3589256
    • (2013) J Natl Cancer Inst , vol.105 , Issue.5 , pp. 342-349
    • Arem, H.1
  • 38
    • 84921826637 scopus 로고    scopus 로고
    • Epidemiology of hepatocellular carcinoma in the United States: Where are we? Where do we go?
    • PMID: 24839253 PMCID: 4211957
    • El-Serag HB and Kanwal F (2014) Epidemiology of hepatocellular carcinoma in the United States: where are we? Where do we go? Hepatology 60(5) 1767-75 DOI: 10.1002/hep.27222 PMID: 24839253 PMCID: 4211957
    • (2014) Hepatology , vol.60 , Issue.5 , pp. 1767-1775
    • El-Serag, H.B.1    Kanwal, F.2
  • 39
    • 84861197159 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace
    • PMID: 22326465
    • Baffy G, Brunt EM and Caldwell SH (2012) Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace J Hepatol 56 1384-91 DOI: 10.1016/j.jhep.2011.10.027 PMID: 22326465
    • (2012) J Hepatol , vol.56 , pp. 1384-1391
    • Baffy, G.1    Brunt, E.M.2    Caldwell, S.H.3
  • 40
    • 84921795197 scopus 로고    scopus 로고
    • Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease
    • PMID: 25632192 PMCID: 4306163
    • Leung C et al (2015) Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease World J Gastroenterol 21(4) 1189-96 DOI: 10.3748/wjg.v21.i4.1189 PMID: 25632192 PMCID: 4306163
    • (2015) World J Gastroenterol , vol.21 , Issue.4 , pp. 1189-1196
    • Leung, C.1
  • 41
    • 0036317748 scopus 로고    scopus 로고
    • Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance
    • PMID: 11872659
    • Franckhauser S et al (2002) Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance Diabetes 51(3) 624-30 DOI: 10.2337/diabetes.51.3.624 PMID: 11872659
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 624-630
    • Franckhauser, S.1
  • 42
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation, and disease
    • PMID: 12832285
    • Cooke MS et al (2003) Oxidative DNA damage: mechanisms, mutation, and disease FASEB J 17(10) 1195-214 DOI: 10.1096/fj.02-0752rev PMID: 12832285
    • (2003) FASEB J , vol.17 , Issue.10 , pp. 1195-1214
    • Cooke, M.S.1
  • 43
    • 72749086094 scopus 로고    scopus 로고
    • An overview of chemical processes that damage cellular DNA: Spontaneous hydrolysis, alkylation, and reactions with radicals
    • PMID: 19757819 PMCID: 2806061
    • Gates KS (2009) An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals Chem Res Toxicol 22(11) 1747-60 DOI: 10.1021/tx900242k PMID: 19757819 PMCID: 2806061
    • (2009) Chem Res Toxicol , vol.22 , Issue.11 , pp. 1747-1760
    • Gates, K.S.1
  • 44
    • 84901917562 scopus 로고    scopus 로고
    • Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
    • Ayala A, Munoz MF and Arguelles S (2014) Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal Oxid Med Cell Longev 22(11) 1747-60 360438 DOI: 10.1155/2014/360438
    • (2014) Oxid Med Cell Longev , vol.22 , Issue.11 , pp. 1747-1760
    • Ayala, A.1    Munoz, M.F.2    Arguelles, S.3
  • 45
    • 0041731614 scopus 로고    scopus 로고
    • Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells
    • PMID: 12775726
    • Niedernhofer LJ et al (2003) Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells J Biol Chem 278(33) 31426-33 DOI: 10.1074/jbc.M212549200 PMID: 12775726
    • (2003) J Biol Chem , vol.278 , Issue.33 , pp. 31426-31433
    • Niedernhofer, L.J.1
  • 46
    • 0029835149 scopus 로고    scopus 로고
    • Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues
    • PMID: 8877062
    • Wang M et al (1996) Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues Cancer Epidemiol Biomarkers Prev 5(9) 705-10 PMID: 8877062
    • (1996) Cancer Epidemiol Biomarkers Prev , vol.5 , Issue.9 , pp. 705-710
    • Wang, M.1
  • 47
    • 84879487933 scopus 로고    scopus 로고
    • High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner
    • PMID: 23726997 PMCID: 3737572
    • Long EK, Olson DM and Bernlohr DA (2013) High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner Free Radic Biol Med 63 390-8 DOI: 10.1016/j.freeradbiomed.2013.05.030 PMID: 23726997 PMCID: 3737572
    • (2013) Free Radic Biol Med , vol.63 , pp. 390-398
    • Long, E.K.1    Olson, D.M.2    Bernlohr, D.A.3
  • 48
    • 41149143613 scopus 로고    scopus 로고
    • Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice
    • PMID: 18311940
    • Singh SP et al (2008) Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice Biochemistry 47(12) 3900-11 DOI: 10.1021/bi702124u PMID: 18311940
    • (2008) Biochemistry , vol.47 , Issue.12 , pp. 3900-3911
    • Singh, S.P.1
  • 49
    • 84859781474 scopus 로고    scopus 로고
    • Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo
    • PMID: 22211372 PMCID: 3285145
    • Akingbade D et al (2012) Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo Chem Res Toxicol 25(2) 454-61 DOI: 10.1021/tx200494h PMID: 22211372 PMCID: 3285145
    • (2012) Chem Res Toxicol , vol.25 , Issue.2 , pp. 454-461
    • Akingbade, D.1
  • 50
    • 0034633645 scopus 로고    scopus 로고
    • Proliferation is necessary for both repair and mutation in transgenic mouse cells
    • PMID: 11005832 PMCID: 17210
    • Bielas JH and Heddle JA (2000) Proliferation is necessary for both repair and mutation in transgenic mouse cells Proc Natl Acad Sci USA 97(21) 11391-6 DOI: 10.1073/pnas.190330997 PMID: 11005832 PMCID: 17210
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.21 , pp. 11391-11396
    • Bielas, J.H.1    Heddle, J.A.2
  • 51
    • 80053997259 scopus 로고    scopus 로고
    • A human memory T cell subset with stem cell-like properties
    • PMID: 21926977 PMCID: 3192229
    • Gattinoni L et al (2011) A human memory T cell subset with stem cell-like properties Nat Med 17(10) 1290-7 DOI: 10.1038/nm.2446 PMID: 21926977 PMCID: 3192229
    • (2011) Nat Med , vol.17 , Issue.10 , pp. 1290-1297
    • Gattinoni, L.1
  • 52
    • 84921288028 scopus 로고    scopus 로고
    • Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions
    • PMID: 25554788 PMCID: 4446723
    • Tomasetti C and Vogelstein B (2015) Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions Science 347(6217) 78-81 DOI: 10.1126/science.1260825 PMID: 25554788 PMCID: 4446723
    • (2015) Science , vol.347 , Issue.6217 , pp. 78-81
    • Tomasetti, C.1    Vogelstein, B.2
  • 53
    • 84868632060 scopus 로고    scopus 로고
    • A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
    • PMID: 22902876 PMCID: 3566224
    • Ito K et al (2012) A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance Nat Med 18(9) 1350-8 DOI: 10.1038/nm.2882 PMID: 22902876 PMCID: 3566224
    • (2012) Nat Med , vol.18 , Issue.9 , pp. 1350-1358
    • Ito, K.1
  • 54
    • 84896135977 scopus 로고    scopus 로고
    • Dietary and metabolic control of stem cell function in physiology and cancer
    • PMID: 24607404 PMCID: 3992244
    • Mihaylova MM Sabatini DM and Yilmaz OH (2014) Dietary and metabolic control of stem cell function in physiology and cancer Cell Stem Cell 14(3) 292-305 DOI: 10.1016/j.stem.2014.02.008 PMID: 24607404 PMCID: 3992244
    • (2014) Cell Stem Cell , vol.14 , Issue.3 , pp. 292-305
    • Mihaylova, M.M.1    Sabatini, D.M.2    Yilmaz, O.H.3
  • 55
    • 84921345437 scopus 로고    scopus 로고
    • Obesity and cancer: Local and systemic mechanisms
    • PMID: 25587653
    • Iyengar NM, Hudis CA and Dannenberg AJ (2015) Obesity and cancer: local and systemic mechanisms Annu Rev Med 66 297-309 DOI: 10.1146/annurev-med-050913-022228 PMID: 25587653
    • (2015) Annu Rev Med , vol.66 , pp. 297-309
    • Iyengar, N.M.1    Hudis, C.A.2    Dannenberg, A.J.3
  • 56
    • 81855225795 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer development in obesity
    • PMID: 22113164
    • Khandekar MJ, Cohen P and Spiegelman BM (2011) Molecular mechanisms of cancer development in obesity Nat Rev Cancer 11(12) 886-95 DOI: 10.1038/nrc3174 PMID: 22113164
    • (2011) Nat Rev Cancer , vol.11 , Issue.12 , pp. 886-895
    • Khandekar, M.J.1    Cohen, P.2    Spiegelman, B.M.3
  • 57
    • 66649098171 scopus 로고    scopus 로고
    • Minireview: Obesity and breast cancer: The estrogen connection
    • PMID: 19372199 PMCID: 2689796
    • Cleary MP and Grossmann ME (2009) Minireview: obesity and breast cancer: the estrogen connection Endocrinology 150(6) 2537-42 DOI: 10.1210/en.2009-0070 PMID: 19372199 PMCID: 2689796
    • (2009) Endocrinology , vol.150 , Issue.6 , pp. 2537-2542
    • Cleary, M.P.1    Grossmann, M.E.2
  • 58
    • 1942422264 scopus 로고    scopus 로고
    • Aromatase: Biologic relevance of tissue-specific expression
    • PMID: 15083377
    • Simpson ER (2004) Aromatase: biologic relevance of tissue-specific expression. Semin Reprod Med 22(1) 11-23 DOI: 10.1055/s-2004-823023 PMID: 15083377
    • (2004) Semin Reprod Med , vol.22 , Issue.1 , pp. 11-23
    • Simpson, E.R.1
  • 59
    • 84917698605 scopus 로고    scopus 로고
    • Updated survey of the steroid-converting enzymes in human adipose tissues
    • Tchernof A et al (2015) Updated survey of the steroid-converting enzymes in human adipose tissues. J Steroid Biochem Mol Biol 147 56-69 DOI: 10.1016/j.jsbmb.2014.11.011
    • (2015) J Steroid Biochem Mol Biol , vol.147 , pp. 56-69
    • Tchernof, A.1
  • 60
    • 79955862214 scopus 로고    scopus 로고
    • Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
    • Subbaramaiah K et al (2011) Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland Cancer Prev Res (Phila) 4(3) 329-46 DOI: 10.1158/1940-6207.CAPR-10-0381
    • (2011) Cancer Prev Res (Phila) , vol.4 , Issue.3 , pp. 329-346
    • Subbaramaiah, K.1
  • 61
    • 84857640868 scopus 로고    scopus 로고
    • The insulin and insulin-like growth factor receptor family in neoplasia: An update
    • PMID: 22337149
    • Pollak M (2012) The insulin and insulin-like growth factor receptor family in neoplasia: an update Nat Rev Cancer 12(3) 159-169 DOI: 10.1038/nrc3215 PMID: 22337149
    • (2012) Nat Rev Cancer , vol.12 , Issue.3 , pp. 159-169
    • Pollak, M.1
  • 62
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • PMID: 20148674
    • Olefsky JM and Glass CK (2010) Macrophages, inflammation, and insulin resistance Annu Rev Physiol 72 219-46 DOI: 10.1146/annurev-physiol-021909-135846 PMID: 20148674
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 63
    • 84868671526 scopus 로고    scopus 로고
    • Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
    • PMID: 22863787 PMCID: 3491143
    • Talukdar S et al (2012) Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase Nat Med 18(9) 1407-12 DOI: 10.1038/nm.2885 PMID: 22863787 PMCID: 3491143
    • (2012) Nat Med , vol.18 , Issue.9 , pp. 1407-1412
    • Talukdar, S.1
  • 64
    • 44849114351 scopus 로고    scopus 로고
    • Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression
    • PMID: 18451161 PMCID: 2928555
    • Anzo M et al (2008) Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression Cancer Res 68(9) 3342-9 DOI: 10.1158/0008-5472.CAN-07-3165 PMID: 18451161 PMCID: 2928555
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3342-3349
    • Anzo, M.1
  • 65
    • 0028890744 scopus 로고
    • The Insulin-like growth factor I receptor: A key to tumor growth?
    • PMID: 7812953
    • Baserga R (1995) The Insulin-like growth factor I receptor: A key to tumor growth? Cancer Res 55(2) 249-52 PMID: 7812953
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 249-252
    • Baserga, R.1
  • 66
    • 66549106493 scopus 로고    scopus 로고
    • The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor
    • PMID: 19228610 PMCID: 2691749
    • Sprynski AC et al (2009) The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor Blood 113(19) 4614-26 DOI: 10.1182/blood-2008-07-170464 PMID: 19228610 PMCID: 2691749
    • (2009) Blood , vol.113 , Issue.19 , pp. 4614-4626
    • Sprynski, A.C.1
  • 67
    • 84865411135 scopus 로고    scopus 로고
    • Diabetes and cancer (2): Evaluating the impact of diabetes on mortality in patients with cancer
    • PMID: 22476948
    • Renehan AG et al (2012) Diabetes and cancer (2): evaluating the impact of diabetes on mortality in patients with cancer Diabetologia 55(6) 1619-32 DOI: 10.1007/s00125-012-2526-0 PMID: 22476948
    • (2012) Diabetologia , vol.55 , Issue.6 , pp. 1619-1632
    • Renehan, A.G.1
  • 68
    • 74049092809 scopus 로고    scopus 로고
    • Calories and carcinogenesis: Lessons learned from 30 years of calorie restriction research
    • Hursting SD et al (2010) Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research Carcinogenesis 31(1) 83-9 DOI: 10.1093/carcin/bgp280
    • (2010) Carcinogenesis , vol.31 , Issue.1 , pp. 83-89
    • Hursting, S.D.1
  • 69
    • 75249094454 scopus 로고    scopus 로고
    • Calorie restriction and cancer prevention: Metabolic and molecular mechanisms
    • PMID: 20097433 PMCID: 2829867
    • Longo VD and Fontana L (2010) Calorie restriction and cancer prevention: metabolic and molecular mechanisms Trends Pharmacol Sci 31(2) 89-8 DOI: 10.1016/j.tips.2009.11.004 PMID: 20097433 PMCID: 2829867
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.2 , pp. 89-98
    • Longo, V.D.1    Fontana, L.2
  • 70
    • 84895727751 scopus 로고    scopus 로고
    • Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
    • PMID: 24606898 PMCID: 3988204
    • Levine ME et al (2014) Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population Cell Metab 19(3) 407-17 DOI: 10.1016/j.cmet.2014.02.006 PMID: 24606898 PMCID: 3988204
    • (2014) Cell Metab , vol.19 , Issue.3 , pp. 407-417
    • Levine, M.E.1
  • 71
    • 84883709817 scopus 로고    scopus 로고
    • AMPK: A target for drugs and natural products with effects on both diabetes and cancer
    • PMID: 23801715 PMCID: 3712072
    • Hardie DG (2013) AMPK: a target for drugs and natural products with effects on both diabetes and cancer Diabetes 62(7) 2164-72 DOI: 10.2337/db13-0368 PMID: 23801715 PMCID: 3712072
    • (2013) Diabetes , vol.62 , Issue.7 , pp. 2164-2172
    • Hardie, D.G.1
  • 72
    • 84919621076 scopus 로고    scopus 로고
    • AMPK - Sensing energy while talking to other signaling pathways
    • PMID: 25448702
    • Hardie DG (2014) AMPK - sensing energy while talking to other signaling pathways Cell Metab 20(6) 939-52 DOI: 10.1016/j.cmet.2014.09.013 PMID: 25448702
    • (2014) Cell Metab , vol.20 , Issue.6 , pp. 939-952
    • Hardie, D.G.1
  • 73
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
    • PMID: 19629071 PMCID: 2756045
    • Shackelford DB and Shaw RJ (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression Nat Rev Cancer 9(8) 563-75 DOI: 10.1038/nrc2676 PMID: 19629071 PMCID: 2756045
    • (2009) Nat Rev Cancer , vol.9 , Issue.8 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 74
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • PMID: 11602624 PMCID: 209533
    • Zhou G et al (2001) Role of AMP-activated protein kinase in mechanism of metformin action J Clin Invest 108(8) 1167-74 DOI: 10.1172/JCI13505 PMID: 11602624 PMCID: 209533
    • (2001) J Clin Invest , vol.108 , Issue.8 , pp. 1167-1174
    • Zhou, G.1
  • 75
    • 77954933558 scopus 로고    scopus 로고
    • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
    • PMID: 20577053 PMCID: 2898585
    • Foretz M et al (2010) Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state J Clin Invest 120(7) 2355-69 DOI: 10.1172/JCI40671 PMID: 20577053 PMCID: 2898585
    • (2010) J Clin Invest , vol.120 , Issue.7 , pp. 2355-2369
    • Foretz, M.1
  • 76
    • 84907296915 scopus 로고    scopus 로고
    • Metformin and cancer risk and mortality: A systematic review and meta-analysis taking into account biases and confounders
    • Gandini S et al (2014) Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders Cancer Prev Res 7(9) 867-85 DOI: 10.1158/1940-6207.CAPR-13-0424
    • (2014) Cancer Prev Res , vol.7 , Issue.9 , pp. 867-885
    • Gandini, S.1
  • 77
    • 78649302320 scopus 로고    scopus 로고
    • Metformin and cancer risk in diabetic patients: A systematic review and meta-analysis
    • Decensi A et al (2010) Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis Cancer Prev Res (Phila) 3(11) 1451-61 DOI: 10.1158/1940-6207.CAPR-10-0157
    • (2010) Cancer Prev Res (Phila) , vol.3 , Issue.11 , pp. 1451-1461
    • Decensi, A.1
  • 78
    • 84869788946 scopus 로고    scopus 로고
    • Metformin and the risk of cancer: Time-related biases in observational studies
    • PMID: 23173135 PMCID: 3507580
    • Suissa S and Azoulay L (2012) Metformin and the risk of cancer: time-related biases in observational studies Diabetes Care 35(12) 2665-73 DOI: 10.2337/dc12-0788 PMID: 23173135 PMCID: 3507580
    • (2012) Diabetes Care , vol.35 , Issue.12 , pp. 2665-2673
    • Suissa, S.1    Azoulay, L.2
  • 79
    • 84866322945 scopus 로고    scopus 로고
    • Investigating metformin for cancer prevention and treatment: The end of the beginning
    • PMID: 22926251
    • Pollak MN (2012) Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov 2(9) 778-90 DOI: 10.1158/2159-8290.CD-12-0263 PMID: 22926251
    • (2012) Cancer Discov , vol.2 , Issue.9 , pp. 778-790
    • Pollak, M.N.1
  • 80
    • 84918586438 scopus 로고    scopus 로고
    • Serine deprivation enhances antineoplastic activity of biguanides
    • PMID: 25377470
    • Gravel SP et al (2014) Serine deprivation enhances antineoplastic activity of biguanides Cancer Res 74(24) 7521-33, DOI: 10.1158/0008-5472.CAN-14-2643-T PMID: 25377470
    • (2014) Cancer Res , vol.74 , Issue.24 , pp. 7521-7533
    • Gravel, S.P.1
  • 81
    • 84877090947 scopus 로고    scopus 로고
    • Molecular pathways: Adiponectin and leptin signaling in cancer
    • PMID: 23355630 PMCID: 3630242
    • VanSaun MN (2013) Molecular pathways: adiponectin and leptin signaling in cancer Clin Cancer Res 19 1926-32, DOI: 10.1158/1078-0432.CCR-12-0930 PMID: 23355630 PMCID: 3630242
    • (2013) Clin Cancer Res , vol.19 , pp. 1926-1932
    • VanSaun, M.N.1
  • 82
    • 84868611621 scopus 로고    scopus 로고
    • Adipocyte-derived endotrophin promotes malignant tumor progression
    • PMID: 23041627 PMCID: 3484450
    • Park J and Scherer PE (2012) Adipocyte-derived endotrophin promotes malignant tumor progression J Clin Invest 122(11) 4243-56 DOI: 10.1172/JCI63930 PMID: 23041627 PMCID: 3484450
    • (2012) J Clin Invest , vol.122 , Issue.11 , pp. 4243-4256
    • Park, J.1    Scherer, P.E.2
  • 83
    • 79953046341 scopus 로고    scopus 로고
    • Inflammatory mechanisms in obesity
    • PMID: 21219177
    • Gregor MF and Hotamisligil GS (2011) Inflammatory mechanisms in obesity Annu Rev Immunol 29 415-45 DOI: 10.1146/annurevimmunol-031210-101322 PMID: 21219177
    • (2011) Annu Rev Immunol , vol.29 , pp. 415-445
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 84
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • PMID: 16175180
    • Karin M and Greten FR (2005) NF-kappaB: linking inflammation and immunity to cancer development and progression Nat Rev Immunol 5 (10) 749-59 DOI: 10.1038/nri1703 PMID: 16175180
    • (2005) Nat Rev Immunol , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 85
    • 84921297135 scopus 로고    scopus 로고
    • Contributions of cell subsets to cytokine production during normal and impaired wound healing
    • Mirza RE and Koh TJ (2015) Contributions of cell subsets to cytokine production during normal and impaired wound healing Cytokine 71(2) 409-12 DOI: 10.1016/j.cyto.2014.09.005
    • (2015) Cytokine , vol.71 , Issue.2 , pp. 409-412
    • Mirza, R.E.1    Koh, T.J.2
  • 86
    • 84896494013 scopus 로고    scopus 로고
    • IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
    • PMID: 24552665
    • Taniguchi K and Karin M (2014) IL-6 and related cytokines as the critical lynchpins between inflammation and cancer Semin Immunol 26(1) 54-74 DOI: 10.1016/j.smim.2014.01.001 PMID: 24552665
    • (2014) Semin Immunol , vol.26 , Issue.1 , pp. 54-74
    • Taniguchi, K.1    Karin, M.2
  • 87
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • PMID: 19185845 PMCID: 2667107
    • Grivennikov S et al (2009) IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Cancer Cell 15(2) 103-13 DOI: 10.1016/j.ccr.2009.01.001 PMID: 19185845 PMCID: 2667107
    • (2009) Cancer Cell , vol.15 , Issue.2 , pp. 103-113
    • Grivennikov, S.1
  • 88
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • PMID: 20141834 PMCID: 2836922
    • Park EJ et al (2010) Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression Cell 140(2) 197-208 DOI: 10.1016/j.cell.2009.12.052 PMID: 20141834 PMCID: 2836922
    • (2010) Cell , vol.140 , Issue.2 , pp. 197-208
    • Park, E.J.1
  • 89
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Bäckhed F et al (2004) The gut microbiota as an environmental factor that regulates fat storage Proc Natl Acad Sci USA 101(44) 15718-23 DOI: 10.1073/pnas.0407076101
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.44 , pp. 15718-15723
    • Bäckhed, F.1
  • 90
    • 84978328160 scopus 로고    scopus 로고
    • Weight gain after fecal microbiota transplantation Open Forum
    • PMID: 26034755 PMCID: 4438885
    • Alang N and Kelly CR Weight gain after fecal microbiota transplantation Open Forum Infect Dis 2(1) DOI: 10.1093/ofid/ofv004 (2015). PMID: 26034755 PMCID: 4438885
    • (2015) Infect Dis , vol.2 , Issue.1
    • Alang, N.1    Kelly, C.R.2
  • 91
    • 84919643021 scopus 로고    scopus 로고
    • High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity
    • PMID: 25174708 PMCID: 4233209
    • Schulz MD et al (2014) High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity Nature 514(7523) 508-12 DOI: 10.1038/nature13398 PMID: 25174708 PMCID: 4233209
    • (2014) Nature , vol.514 , Issue.7523 , pp. 508-512
    • Schulz, M.D.1
  • 92
    • 84879888338 scopus 로고    scopus 로고
    • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
    • PMID: 23803760
    • Yoshimoto S et al (2013) Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome Nature 499(7456) 97-101, http://www.nature.com/nature/journal/v499/n7456/abs/nature12347.html - supplementary-information DOI: 10.1038/nature12347 PMID: 23803760
    • (2013) Nature , vol.499 , Issue.7456 , pp. 97-101
    • Yoshimoto, S.1
  • 93
    • 35448941550 scopus 로고    scopus 로고
    • Dosing in obesity: A simple solution to a big problem
    • PMID: 17952107
    • Han PY et al (2007) Dosing in obesity: a simple solution to a big problem Clin Pharmacol Ther 82(5) 505-8 DOI: 10.1038/sj.clpt.6100381 PMID: 17952107
    • (2007) Clin Pharmacol Ther , vol.82 , Issue.5 , pp. 505-508
    • Han, P.Y.1
  • 94
    • 57749203554 scopus 로고    scopus 로고
    • Influence of lean body weight on anticancer drug clearance
    • Mathijssen RHJ and Sparreboom A (2009) Influence of lean body weight on anticancer drug clearance Clinical Pharmacol Ther 85(1) 23 DOI: 10.1038/sj.clpt.6100511
    • (2009) Clinical Pharmacol Ther , vol.85 , Issue.1 , pp. 23
    • Mathijssen, R.H.J.1    Sparreboom, A.2
  • 95
    • 84881479689 scopus 로고    scopus 로고
    • Chemotherapy dosing in overweight and obese patients with cancer
    • PMID: 23856744
    • Lyman GH and Sparreboom A (2013) Chemotherapy dosing in overweight and obese patients with cancer Nat Rev Clin Oncol 10(8) 451-9 DOI: 10.1038/nrclinonc.2013.108 PMID: 23856744
    • (2013) Nat Rev Clin Oncol , vol.10 , Issue.8 , pp. 451-459
    • Lyman, G.H.1    Sparreboom, A.2
  • 96
    • 25144466036 scopus 로고    scopus 로고
    • Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index
    • PMID: 16182899
    • Colleoni M et al (2005) Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index Lancet 366(9491) 1108-10 DOI: 10.1016/S0140-6736(05)67110-3 PMID: 16182899
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1108-1110
    • Colleoni, M.1
  • 97
    • 84893701642 scopus 로고    scopus 로고
    • Effect of obesity on disease-free and overall survival in node-positive breast cancer patients in a large French population: A pooled analysis of two randomised trials
    • Ladoire S et al (2014) Effect of obesity on disease-free and overall survival in node-positive breast cancer patients in a large French population: a pooled analysis of two randomised trials Eur J Cancer 50(3) 506-16 DOI: 10.1016/j.ejca.2013.11.013
    • (2014) Eur J Cancer , vol.50 , Issue.3 , pp. 506-516
    • Ladoire, S.1
  • 98
    • 84925511457 scopus 로고    scopus 로고
    • Impact of body mass index on neoadjuvant treatment outcome: A pooled analysis of eight prospective neoadjuvant breast cancer trials
    • PMID: 25677740
    • Fontanella C et al (2015) Impact of body mass index on neoadjuvant treatment outcome: a pooled analysis of eight prospective neoadjuvant breast cancer trials Breast Cancer Res Treat 150(1) 127-39 DOI: 10.1007/s10549-015-3287-5 PMID: 25677740
    • (2015) Breast Cancer Res Treat , vol.150 , Issue.1 , pp. 127-139
    • Fontanella, C.1
  • 99
    • 84862986506 scopus 로고    scopus 로고
    • Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline
    • PMID: 22473167
    • Griggs JJ et al Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline J Clin Oncol 30(13) 1553-61 DOI: 10.1200/jco.2011.39.9436 PMID: 22473167
    • J Clin Oncol , vol.30 , Issue.13 , pp. 1553-1561
    • Griggs, J.J.1
  • 100
    • 84906226398 scopus 로고    scopus 로고
    • Incidence of cancer following bariatric surgery: Systematic review and meta-analysis
    • PMID: 24817500
    • Casagrande DS et al (2014) Incidence of cancer following bariatric surgery: systematic review and meta-analysis Obes Surg 24(9) 1499-1509 DOI: 10.1007/s11695-014-1276-0 PMID: 24817500
    • (2014) Obes Surg , vol.24 , Issue.9 , pp. 1499-1509
    • Casagrande, D.S.1
  • 101
    • 84876573053 scopus 로고    scopus 로고
    • Population-wide weight loss and regain in relation to diabetes burden and cardiovascular mortality in Cuba 1980-2010 repeated cross sectional surveys and ecological comparison of secular trends
    • Franco M et al (2013) Population-wide weight loss and regain in relation to diabetes burden and cardiovascular mortality in Cuba 1980-2010 repeated cross sectional surveys and ecological comparison of secular trends BMJ 346 f1515 DOI: 10.1136/bmj.f1515
    • (2013) BMJ , vol.346
    • Franco, M.1
  • 102
    • 34447512756 scopus 로고    scopus 로고
    • Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: The Women's Healthy Eating and Living (WHEL) randomized trial
    • PMID: 17635889 PMCID: 2083253
    • Pierce JP et al (2007) Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial JAMA 298(3) 289-98 DOI: 10.1001/jama.298.3.289 PMID: 17635889 PMCID: 2083253
    • (2007) JAMA , vol.298 , Issue.3 , pp. 289-298
    • Pierce, J.P.1
  • 103
    • 33845894946 scopus 로고    scopus 로고
    • Dietary Fat Reduction and Breast Cancer Outcome: Interim Efficacy Results from the Women's Intervention Nutrition Study
    • PMID: 17179478
    • Chlebowski RT et al (2006) Dietary Fat Reduction and Breast Cancer Outcome: Interim Efficacy Results From the Women's Intervention Nutrition Study J Natl Cancer Inst 98(24) 1767-76 DOI: 10.1093/jnci/djj494 PMID: 17179478
    • (2006) J Natl Cancer Inst , vol.98 , Issue.24 , pp. 1767-1776
    • Chlebowski, R.T.1
  • 104
    • 84907339499 scopus 로고    scopus 로고
    • Comparison of weight loss among named diet programs in overweight and obese adults: A meta-analysis
    • PMID: 25182101
    • Johnston BC et al (2014) Comparison of weight loss among named diet programs in overweight and obese adults: A meta-analysis JAMA 312(9) 923-33 DOI: 10.1001/jama.2014.10397 PMID: 25182101
    • (2014) JAMA , vol.312 , Issue.9 , pp. 923-933
    • Johnston, B.C.1
  • 105
    • 84926322761 scopus 로고    scopus 로고
    • Vegetarian dietary patterns and the risk of colorectal cancers JAMA
    • PMID: 25751512 PMCID: 4420687
    • Orlich MJ et al (2015) Vegetarian dietary patterns and the risk of colorectal cancers JAMA Intern Med 175(5) 767-76 DOI: 10.1001/jamainternmed.2015.59 PMID: 25751512 PMCID: 4420687
    • (2015) Intern Med , vol.175 , Issue.5 , pp. 767-776
    • Orlich, M.J.1
  • 106
    • 67649846426 scopus 로고    scopus 로고
    • Cancer incidence in British vegetarians
    • PMID: 19536095 PMCID: 2699384
    • Key TJ et al (2009) Cancer incidence in British vegetarians Br J Cancer 101(1) 192-7 DOI: 10.1038/sj.bjc.6605098 PMID: 19536095 PMCID: 2699384
    • (2009) Br J Cancer , vol.101 , Issue.1 , pp. 192-197
    • Key, T.J.1
  • 107
    • 65549110317 scopus 로고    scopus 로고
    • Cancer incidence in vegetarians: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)
    • PMID: 19279082
    • Key TJ et al (2009) Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford) Am J Clin Nutr 89(5) 1620S-1626S DOI: 10.3945/ajcn.2009.26736M PMID: 19279082
    • (2009) Am J Clin Nutr , vol.89 , Issue.5 , pp. 1620S-1626S
    • Key, T.J.1
  • 108
    • 64749108996 scopus 로고    scopus 로고
    • Tumours with PI3K activation are resistant to dietary restriction
    • PMID: 19279572 PMCID: 2692085
    • Kalaany NY and Sabatini DM (2009) Tumours with PI3K activation are resistant to dietary restriction Nature 458 (7239) 725-31 DOI: 10.1038/nature07782 PMID: 19279572 PMCID: 2692085
    • (2009) Nature , vol.458 , Issue.7239 , pp. 725-731
    • Kalaany, N.Y.1    Sabatini, D.M.2
  • 109
    • 84906275781 scopus 로고    scopus 로고
    • Weight loss intervention trials in women with breast cancer: A systematic review
    • PMID: 24891269
    • Reeves MM et al (2014) Weight loss intervention trials in women with breast cancer: a systematic review Obes Rev 15(9) 749-68 DOI: 10.1111/obr.12190 PMID: 24891269
    • (2014) Obes Rev , vol.15 , Issue.9 , pp. 749-768
    • Reeves, M.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.