Clinical significance of MLH1 methylation and CpG island methylator phenotype as prognostic markers in patients with gastric cancer

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Shigeyasu, Kunitoshi ^a,b   Nagasaka, Takeshi ^a   Mori, Yoshiko ^a   Yokomichi, Naosuke ^a   Kawai, Takashi ^a   Fuji, Tomokazu ^a   Kimura, Keisuke ^a   Umeda, Yuzo ^a   Kagawa, Shunsuke ^a   Goel, Ajay ^b   Fujiwara, Toshiyoshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MLH1; TUMOR MARKER; MICROSATELLITE DNA; MLH1 PROTEIN, HUMAN; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AGE; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COHORT ANALYSIS; CPG ISLAND; FEMALE; GENE FUNCTION; GENE LOCUS; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE INSTABILITY; MICROSATELLITE MARKER; MLH1 GENE; ONCOGENE K RAS; OVERALL SURVIVAL; PHENOTYPE; PREDICTION; PROMOTER REGION; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH SURGERY; TUMOR DIFFERENTIATION; DISEASE FREE SURVIVAL; DNA METHYLATION; GENETIC DATABASE; GENETICS; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; STOMACH TUMOR; TREATMENT OUTCOME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; COHORT STUDIES; CPG ISLANDS; DATABASES, GENETIC; DISEASE-FREE SURVIVAL; DNA METHYLATION; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MIDDLE AGED; MULTIVARIATE ANALYSIS; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEINS; PHENOTYPE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; STOMACH NEOPLASMS; TREATMENT OUTCOME;

EID: 84938633282     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130409     Document Type: Article

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