-
1
-
-
0030710153
-
How does DNA methylation repress transcription?
-
Kass SU, Pruss D, Wolffe AP. How does DNA methylation repress transcription? Trends Genet 1997; 13: 444-9.
-
(1997)
Trends Genet.
, vol.13
, pp. 444-449
-
-
Kass, S.U.1
Pruss, D.2
Wolffe, A.P.3
-
2
-
-
0025945632
-
DNA methylation and gene expression
-
Razin A, Cedar H. DNA methylation and gene expression. Microbiol Rev 1991; 55: 451-8.
-
(1991)
Microbiol. Rev.
, vol.55
, pp. 451-458
-
-
Razin, A.1
Cedar, H.2
-
3
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995; 1: 686-92.
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
4
-
-
0033229890
-
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype
-
Toyota M, Ahuja N, Suzuki H, Itoh F, Ohe-Toyota M, Imai K, Baylin SB, Issa JP. Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res 1999;59: 5438-42.
-
(1999)
Cancer Res.
, vol.59
, pp. 5438-5442
-
-
Toyota, M.1
Ahuja, N.2
Suzuki, H.3
Itoh, F.4
Ohe-Toyota, M.5
Imai, K.6
Baylin, S.B.7
Issa, J.P.8
-
5
-
-
0037137871
-
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer
-
Kikuchi T, Itoh F, Toyota M, Suzuki H, Yamamoto H, Fujita M, Hosokawa M, Imai K. Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. Int J Cancer 2002; 97: 272-7.
-
(2002)
Int. J. Cancer
, vol.97
, pp. 272-277
-
-
Kikuchi, T.1
Itoh, F.2
Toyota, M.3
Suzuki, H.4
Yamamoto, H.5
Fujita, M.6
Hosokawa, M.7
Imai, K.8
-
6
-
-
0036127525
-
Promoter methylation and silencing of PTEN in gastric carcinoma
-
Kang YH, Lee HS, Kim WH. Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest 2002; 82: 285-91.
-
(2002)
Lab. Invest.
, vol.82
, pp. 285-291
-
-
Kang, Y.H.1
Lee, H.S.2
Kim, W.H.3
-
7
-
-
0035885227
-
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma
-
Oue N, Shigeishi H, Kuniyasu H, Yokozaki H, Kuraoka K, Ito R, Yasui W. Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma. Int J Cancer 2001; 93: 805-9.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 805-809
-
-
Oue, N.1
Shigeishi, H.2
Kuniyasu, H.3
Yokozaki, H.4
Kuraoka, K.5
Ito, R.6
Yasui, W.7
-
8
-
-
0035476236
-
Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma
-
Byun DS, Lee MG, Chae KS, Ryu BG, Chi SG. Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma. Cancer Res 2001; 61: 7034-8.
-
(2001)
Cancer Res.
, vol.61
, pp. 7034-7038
-
-
Byun, D.S.1
Lee, M.G.2
Chae, K.S.3
Ryu, B.G.4
Chi, S.G.5
-
9
-
-
0035360797
-
Transcriptional silencing of cyclooxygenase-2 by hypermethylation of the 5′ CpG island in human gastric carcinoma cells
-
Song SH, Jong HS, Choi HH, Inoue H, Tanabe T, Kim NK, Bang YJ. Transcriptional silencing of cyclooxygenase-2 by hypermethylation of the 5′ CpG island in human gastric carcinoma cells. Cancer Res 2001; 61: 4628-35.
-
(2001)
Cancer Res.
, vol.61
, pp. 4628-4635
-
-
Song, S.H.1
Jong, H.S.2
Choi, H.H.3
Inoue, H.4
Tanabe, T.5
Kim, N.K.6
Bang, Y.J.7
-
10
-
-
0034662605
-
Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers
-
Suzuki H, Itoh F, Toyota M, Kikuchi T, Kakiuchi H, Imai K. Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers. Cancer Res 2000; 60: 4353-7.
-
(2000)
Cancer Res.
, vol.60
, pp. 4353-4357
-
-
Suzuki, H.1
Itoh, F.2
Toyota, M.3
Kikuchi, T.4
Kakiuchi, H.5
Imai, K.6
-
11
-
-
0342748644
-
Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas
-
Shim YH, Kang GH, Ro JY. Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas. Lab Invest 2000; 80: 689-95.
-
(2000)
Lab. Invest.
, vol.80
, pp. 689-695
-
-
Shim, Y.H.1
Kang, G.H.2
Ro, J.Y.3
-
12
-
-
0033105363
-
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability
-
Fleisher AS, Esteller M, Wang S, Tamura G, Suzuki H, Yin J, Zou TT, Abraham JM, Kong D, Smolinski KN, Shi YQ, Rhyu MG, Powell SM, James SP, Wilson KT, Herman JG, Meltzer SJ. Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res 1999; 59: 1090-5.
-
(1999)
Cancer Res.
, vol.59
, pp. 1090-1095
-
-
Fleisher, A.S.1
Esteller, M.2
Wang, S.3
Tamura, G.4
Suzuki, H.5
Yin, J.6
Zou, T.T.7
Abraham, J.M.8
Kong, D.9
Smolinski, K.N.10
Shi, Y.Q.11
Rhyu, M.G.12
Powell, S.M.13
James, S.P.14
Wilson, K.T.15
Herman, J.G.16
Meltzer, S.J.17
-
13
-
-
0001119305
-
hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability
-
Leung SY, Yuen ST, Chung LP, Chu KM, Chan AS, Ho JC. hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability. Cancer Res 1999; 59: 159-64.
-
(1999)
Cancer Res.
, vol.59
, pp. 159-164
-
-
Leung, S.Y.1
Yuen, S.T.2
Chung, L.P.3
Chu, K.M.4
Chan, A.S.5
Ho, J.C.6
-
14
-
-
0034935235
-
Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer
-
Sato K, Tamura G, Tsuchiya T, Endoh Y, Usuba O, Kimura W, Motoyama T. Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer. Br J Cancer 2001; 85: 199-203.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 199-203
-
-
Sato, K.1
Tamura, G.2
Tsuchiya, T.3
Endoh, Y.4
Usuba, O.5
Kimura, W.6
Motoyama, T.7
-
15
-
-
0037112529
-
Identification of silencing of nine genes in human gastric cancers
-
Kaneda A, Kaminishi M, Yanagihara K, Sugimura T, Ushijima T. Identification of silencing of nine genes in human gastric cancers. Cancer Res 2001; 62: 6645-50.
-
(2001)
Cancer Res.
, vol.62
, pp. 6645-6650
-
-
Kaneda, A.1
Kaminishi, M.2
Yanagihara, K.3
Sugimura, T.4
Ushijima, T.5
-
16
-
-
0036121312
-
Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma
-
Kang GH, Lee S, Kim WH, Lee HW, Kim JC, Rhyu MG, Ro JY. Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol 2002; 160: 787-94.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 787-794
-
-
Kang, G.H.1
Lee, S.2
Kim, W.H.3
Lee, H.W.4
Kim, J.C.5
Rhyu, M.G.6
Ro, J.Y.7
-
17
-
-
12644292106
-
The two histological main types of gastric carcinoma. Diffuse and so-called intestinal type carcinoma: An attempt at histological classification
-
Lauren P. The two histological main types of gastric carcinoma. Diffuse and so-called intestinal type carcinoma: an attempt at histological classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.
-
(1965)
Acta Pathol. Microbiol. Scand.
, vol.64
, pp. 31-49
-
-
Lauren, P.1
-
18
-
-
0025846923
-
Expression of E- and P-cadherin in gastric carcinomas
-
Shimoyama Y, Hirohashi S. Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 1991; 51: 2185-92.
-
(1991)
Cancer Res.
, vol.51
, pp. 2185-2192
-
-
Shimoyama, Y.1
Hirohashi, S.2
-
19
-
-
0035724734
-
Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa
-
Oue N, Sentani K, Yokozaki H, Kitadai Y, Ito R, Yasui W. Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa. Pathobiology 2001; 69: 143-9.
-
(2001)
Pathobiology
, vol.69
, pp. 143-149
-
-
Oue, N.1
Sentani, K.2
Yokozaki, H.3
Kitadai, Y.4
Ito, R.5
Yasui, W.6
-
20
-
-
0036724347
-
Distinct promoter hypermethylation of p16INK4A, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered-type gastric carcinomas
-
Oue N, Motoshita J, Yokozaki H, Hayashi K, Tahara E, Taniyama K, Matsusaki K, Yasui W. Distinct promoter hypermethylation of p16INK4A, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered-type gastric carcinomas. J Pathol 2002; 198: 55-9.
-
(2002)
J. Pathol.
, vol.198
, pp. 55-59
-
-
Oue, N.1
Motoshita, J.2
Yokozaki, H.3
Hayashi, K.4
Tahara, E.5
Taniyama, K.6
Matsusaki, K.7
Yasui, W.8
-
21
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93: 9821-6.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
22
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-7.
-
(1999)
Cancer Res.
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
Baylin, S.B.4
Herman, J.G.5
-
23
-
-
0034679027
-
Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer
-
Widschwendter M, Berger J, Hermann M, Muller HM, Amberger A, Zeschnigk M, Widschwendter A, Abendstein B, Zeimet AG, Daxenbichler G, Marth C. Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer. J Natl Cancer Inst 2000; 92: 826-32.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 826-832
-
-
Widschwendter, M.1
Berger, J.2
Hermann, M.3
Muller, H.M.4
Amberger, A.5
Zeschnigk, M.6
Widschwendter, A.7
Abendstein, B.8
Zeimet, A.G.9
Daxenbichler, G.10
Marth, C.11
-
24
-
-
0035328527
-
Accelerated age-related CpG island methylation in ulcerative colitis
-
Issa JP, Ahuja N, Toyota M, Bronner MP, Brentnall TA. Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res 2001; 61: 3573-7.
-
(2001)
Cancer Res.
, vol.61
, pp. 3573-3577
-
-
Issa, J.P.1
Ahuja, N.2
Toyota, M.3
Bronner, M.P.4
Brentnall, T.A.5
-
25
-
-
0034607246
-
E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas
-
Tamura G, Yin J, Wang S, Fleisher AS, Zou T, Abraham JM, Kong D, Smolinski KN, Wilson KT, James SP, Silverberg SG, Nishizuka S, Terashima M, Motoyama T, Meltzer SJ. E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas. J Natl Cancer Inst 2000; 92: 569-73.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 569-573
-
-
Tamura, G.1
Yin, J.2
Wang, S.3
Fleisher, A.S.4
Zou, T.5
Abraham, J.M.6
Kong, D.7
Smolinski, K.N.8
Wilson, K.T.9
James, S.P.10
Silverberg, S.G.11
Nishizuka, S.12
Terashima, M.13
Motoyama, T.14
Meltzer, S.J.15
-
26
-
-
0032848687
-
Distinct methylation pattern and microsatellite instability in sporadic gastric cancer
-
Suzuki H, Itoh F, Toyota M, Kikuchi T, Kakiuchi H, Hinoda Y, Imai K. Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. Int J Cancer 1999; 83: 309-13.
-
(1999)
Int. J. Cancer
, vol.83
, pp. 309-313
-
-
Suzuki, H.1
Itoh, F.2
Toyota, M.3
Kikuchi, T.4
Kakiuchi, H.5
Hinoda, Y.6
Imai, K.7
-
27
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S, Pelicci PG. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002; 295: 1079-82.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
Fazi, F.4
Fanelli, M.5
Faretta, M.6
Fuks, F.7
Lo Coco, F.8
Kouzarides, T.9
Nervi, C.10
Minucci, S.11
Pelicci, P.G.12
-
28
-
-
0035888252
-
Age-related hypermethylation of the hMLH1 promoter in gastric cancers
-
Nakajima T, Akiyama Y, Shiraishi J, Arai T, Yanagisawa Y, Ara M, Fukuda Y, Sawabe M, Saitoh K, Kamiyama R, Hirokawa K, Yuasa Y. Age-related hypermethylation of the hMLH1 promoter in gastric cancers. Int J Cancer 2001; 94: 208-11.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 208-211
-
-
Nakajima, T.1
Akiyama, Y.2
Shiraishi, J.3
Arai, T.4
Yanagisawa, Y.5
Ara, M.6
Fukuda, Y.7
Sawabe, M.8
Saitoh, K.9
Kamiyama, R.10
Hirokawa, K.11
Yuasa, Y.12
-
29
-
-
0035117307
-
Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
-
Whitehall VL, Walsh MD, Young J, Leggett BA, Jass JR. Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability. Cancer Res 2001; 61: 827-30.
-
(2001)
Cancer Res.
, vol.61
, pp. 827-830
-
-
Whitehall, V.L.1
Walsh, M.D.2
Young, J.3
Leggett, B.A.4
Jass, J.R.5
-
30
-
-
0025777363
-
Association of Epstein-Barr virus with undifferentiated gastric carcinomas with intense lymphoid infiltration. Lymphoepithelioma-like carcinoma
-
Shibata D, Tokunaga M, Uemura Y, Sato E, Tanaka S, Weiss LM. Association of Epstein-Barr virus with undifferentiated gastric carcinomas with intense lymphoid infiltration. Lymphoepithelioma-like carcinoma. Am J Pathol 1991; 139: 469-74.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 469-474
-
-
Shibata, D.1
Tokunaga, M.2
Uemura, Y.3
Sato, E.4
Tanaka, S.5
Weiss, L.M.6
-
31
-
-
0028577894
-
Gastric carcinoma: Monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein
-
Imai S, Koizumi S, Sugiura M, Tokunaga M, Uemura Y, Yamamoto N, Tanaka S, Sato E, Osato T. Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein. Proc Natl Acad Sci USA 1994; 91: 9131-5.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9131-9135
-
-
Imai, S.1
Koizumi, S.2
Sugiura, M.3
Tokunaga, M.4
Uemura, Y.5
Yamamoto, N.6
Tanaka, S.7
Sato, E.8
Osato, T.9
-
32
-
-
0028173716
-
Epstein-Barr virus in gastric carcinoma with lymphoid stroma. Special reference to its detection by the polymerase chain reaction and in situ hybridization in 99 tumors, including a morphologic analysis
-
Nakamura S, Ueki T, Yao T, Ueyama T, Tsuneyoshi M. Epstein-Barr virus in gastric carcinoma with lymphoid stroma. Special reference to its detection by the polymerase chain reaction and in situ hybridization in 99 tumors, including a morphologic analysis. Cancer 1994; 73: 2239-49.
-
(1994)
Cancer
, vol.73
, pp. 2239-2249
-
-
Nakamura, S.1
Ueki, T.2
Yao, T.3
Ueyama, T.4
Tsuneyoshi, M.5
-
33
-
-
0033135049
-
Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression
-
Deng G, Chen A, Hong J, Chae HS, Kim YS. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res 1999; 59: 2029-33.
-
(1999)
Cancer Res.
, vol.59
, pp. 2029-2033
-
-
Deng, G.1
Chen, A.2
Hong, J.3
Chae, H.S.4
Kim, Y.S.5
-
34
-
-
0029114538
-
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
-
Yoshiura K, Kanai Y, Ochiai A, Shimoyama Y, Sugimura T, Hirohashi S. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci USA 1995; 92: 7416-9.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7416-7419
-
-
Yoshiura, K.1
Kanai, Y.2
Ochiai, A.3
Shimoyama, Y.4
Sugimura, T.5
Hirohashi, S.6
-
35
-
-
0035452392
-
The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas
-
Nakayama S, Sasaki A, Mese H, Alcalde RE, Tsuji T, Matsumura T. The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas. Int J Cancer 2001; 93: 667-73.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 667-673
-
-
Nakayama, S.1
Sasaki, A.2
Mese, H.3
Alcalde, R.E.4
Tsuji, T.5
Matsumura, T.6
-
36
-
-
0035725107
-
Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer
-
Hayashi K, Yokozaki H, Goodison S, Oue N, Suzuki T, Lotan R, Yasui W, Tahara E. Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer. Differentiation 2001; 68: 13-21.
-
(2001)
Differentiation
, vol.68
, pp. 13-21
-
-
Hayashi, K.1
Yokozaki, H.2
Goodison, S.3
Oue, N.4
Suzuki, T.5
Lotan, R.6
Yasui, W.7
Tahara, E.8
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