Mitochondrial fission augments capsaicin-induced axonal degeneration

Acta Neuropathologica

Volumn 129, Issue 1, 2015, Pages 81-96

  Chiang, Hao ^a,b   Ohno, Nobuhiko ^b,d   Hsieh, Yu Lin ^a,e   Mahad, Don J ^b,f   Kikuchi, Shin ^b,g   Komuro, Hitoshi ^b   Hsieh, Sung Tsang ^a,c   Trapp, Bruce D ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d UNIVERSITY OF YAMANASHI   (Japan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

^g SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Axonal swellings; Capsaicin; Drp1; Miro; Mitochondria

Indexed keywords

CALCIUM ION; CAPSAICIN; DYNAMIN RELATED PROTEIN 1; PROTEIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; CALCIUM; TRPV1 PROTEIN, MOUSE; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXOPLASM; CAPSAICIN INDUCED AXONAL DEGENERATION; CELL TRANSPORT; CONTROLLED STUDY; EXPERIMENTAL NEUROLOGIC DISEASE; IN VITRO STUDY; INTERNAL RIBOSOME ENTRY SITE; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL VOLUME; MOUSE; NERVE FIBER; NERVE FIBER DEGENERATION; NEUROFILAMENT; NONHUMAN; NONMYELINATED NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; ANIMAL; AXON; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MITOCHONDRION; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ANIMALS; AXONS; CALCIUM; CAPSAICIN; CELLS, CULTURED; GANGLIA, SPINAL; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED ICR; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; NERVE DEGENERATION; RATS, SPRAGUE-DAWLEY; TRPV CATION CHANNELS;

EID: 84938603886     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1354-3     Document Type: Article

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