Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration

Journal of Neuroscience

Volumn 32, Issue 12, 2012, Pages 4145-4155

  Misko, Albert L ^a   Sasaki, Yo ^a   Tuck, Elizabeth ^a   Milbrandt, Jeffrey ^a   Baloh, Robert H ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOFUSIN 1; MITOFUSIN 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CALCIUM HOMEOSTASIS; CELL FUSION; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENE SILENCING; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CELL; MICROSCOPY; NERVE FIBER DEGENERATION; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ARGININE; AXONS; CALCIUM; DEOXYGLUCOSE; EMBRYO, MAMMALIAN; FLUORESCEINS; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GLUTAMINE; GREEN FLUORESCENT PROTEINS; GTP PHOSPHOHYDROLASES; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURONS; POINT MUTATION; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TRANSFECTION;

EID: 84858397292     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6338-11.2012     Document Type: Article

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