메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages

Potential protective properties of flax lignan secoisolariciresinol diglucoside

Author keywords

Diet; Flaxseed; Lignan; Maladies; Precursors; Processing; Therapy

Indexed keywords

C REACTIVE PROTEIN; ESTROGEN; LIGNAN; LINOLEIC ACID; NUTRACEUTICAL; PLACEBO; SECOISOLARICIRESINOL DIGLUCOSIDE; UNCLASSIFIED DRUG; ANTIOXIDANT; BUTANEDIOL; GLUCOSIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT;

EID: 84938423480     PISSN: None     EISSN: 14752891     Source Type: Journal    
DOI: 10.1186/s12937-015-0059-3     Document Type: Article
Times cited : (108)

References (70)
  • 2
    • 84865276527 scopus 로고    scopus 로고
    • Lignans in seeds of Linum species
    • 1:CAS:528:DC%2BC38Xht1egt7fK
    • Schmidt TJ, Klaes M, Sendker J. Lignans in seeds of Linum species. Phytochem. 2012;82:89-99.
    • (2012) Phytochem , vol.82 , pp. 89-99
    • Schmidt, T.J.1    Klaes, M.2    Sendker, J.3
  • 3
    • 84896892709 scopus 로고    scopus 로고
    • Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans
    • 1:CAS:528:DC%2BC2cXjt12js7g%3D
    • Setchell KD, Brown NM, Zimmer-Nechemias L, Wolfe B, Jha P, Heubi JE. Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans. Food Funct. 2014;5:491-501.
    • (2014) Food Funct , vol.5 , pp. 491-501
    • Setchell, K.D.1    Brown, N.M.2    Zimmer-Nechemias, L.3    Wolfe, B.4    Jha, P.5    Heubi, J.E.6
  • 4
    • 84892472526 scopus 로고    scopus 로고
    • Phenolic compounds in flaxseed: A review of their properties and analytical methods. An overview of the last decade
    • 1:CAS:528:DC%2BC2cXntVyhsw%3D%3D
    • Herchi W, Arráez-Román D, Trabelsi H, Bouali I, Boukhchina S, Kallel H, et al. Phenolic compounds in flaxseed: a review of their properties and analytical methods. An overview of the last decade. J Oleo Sci. 2014;63:7-14.
    • (2014) J Oleo Sci , vol.63 , pp. 7-14
    • Herchi, W.1    Arráez-Román, D.2    Trabelsi, H.3    Bouali, I.4    Boukhchina, S.5    Kallel, H.6
  • 5
    • 33751079114 scopus 로고    scopus 로고
    • Pinoresinol-lariciresinol reductase gene expression and secoisolariciresinol diglucoside accumulation in developing flax (Linum usitatissimum) seeds
    • 1:CAS:528:DC%2BD28Xht1WnsrbO
    • Hano C, Martin I, Fliniaux O, Legrand B, Gutierrez L, Arroo RR, et al. Pinoresinol-lariciresinol reductase gene expression and secoisolariciresinol diglucoside accumulation in developing flax (Linum usitatissimum) seeds. Planta. 2006;224:1291-301.
    • (2006) Planta , vol.224 , pp. 1291-1301
    • Hano, C.1    Martin, I.2    Fliniaux, O.3    Legrand, B.4    Gutierrez, L.5    Arroo, R.R.6
  • 6
    • 55949089638 scopus 로고    scopus 로고
    • The effectiveness of hydrotherapy in the management of fibromyalgia syndrome: A systematic review
    • 10.1007/s00296-008-0674-9
    • McVeigh JG, McGaughey H, Hall M, Kane P. The effectiveness of hydrotherapy in the management of fibromyalgia syndrome: a systematic review. Rheumatol Int. 2008. doi: 10.1007/s00296-008-0674-9.
    • (2008) Rheumatol Int
    • McVeigh, J.G.1    McGaughey, H.2    Hall, M.3    Kane, P.4
  • 7
    • 0001877711 scopus 로고    scopus 로고
    • Variation in the concentration of the flax seed lignan concentration with variety, location and year
    • Fargo, ND, Flax Institute of the United States
    • Westcott ND, Muir AD. Variation in the concentration of the flax seed lignan concentration with variety, location and year. In: Proc 56th Flax Institute of the United States Conference 1996, Fargo, ND, Flax Institute of the United States, pp 77-80
    • Proc 56th Flax Institute of the United States Conference 1996 , pp. 77-80
    • Westcott, N.D.1    Muir, A.D.2
  • 8
    • 78049426491 scopus 로고    scopus 로고
    • Patented techniques for the extraction and isolation of secoisolari-ciresinol diglucoside from flaxseed
    • 1:CAS:528:DC%2BD1MXjtVyjurc%3D
    • Hosseinian FS, Beta T. Patented techniques for the extraction and isolation of secoisolari-ciresinol diglucoside from flaxseed. Recent Pat Food Nutr Agric. 2009;1:25-31.
    • (2009) Recent Pat Food Nutr Agric , vol.1 , pp. 25-31
    • Hosseinian, F.S.1    Beta, T.2
  • 11
    • 84938420552 scopus 로고    scopus 로고
    • Development and validation of an efficient ultrasound assisted extraction of phenolic compounds from flax (Linum usitatissimum L.) seeds
    • 1:CAS:528:DC%2BC2MXjslyjtL4%3D
    • Corbin C, Fidel T, Leclerc EA, Barakzoy E, Sagot N, Falguieres A, et al. Development and validation of an efficient ultrasound assisted extraction of phenolic compounds from flax (Linum usitatissimum L.) seeds. Ultrason Sonochem. 2015;26:176-85.
    • (2015) Ultrason Sonochem , vol.26 , pp. 176-185
    • Corbin, C.1    Fidel, T.2    Leclerc, E.A.3    Barakzoy, E.4    Sagot, N.5    Falguieres, A.6
  • 12
    • 3843064320 scopus 로고    scopus 로고
    • High performance thin-layer chromatographic-densitometric determination of secoisolariciresinol diglucoside in flaxseed
    • 1:CAS:528:DC%2BD2cXmtVagsb0%3D
    • Coran SA, Giannellini V, Bambagiotti-Alberti M. High performance thin-layer chromatographic-densitometric determination of secoisolariciresinol diglucoside in flaxseed. J Chromatogr A. 2004;1045:217-22.
    • (2004) J Chromatogr A , vol.1045 , pp. 217-222
    • Coran, S.A.1    Giannellini, V.2    Bambagiotti-Alberti, M.3
  • 13
    • 57749121208 scopus 로고    scopus 로고
    • Determination of lignans in flaxseed using liquid chromatography with time-of-flight mass spectrometry
    • 1:CAS:528:DC%2BD1cXhsFClsrfF
    • Popova IE, Hall C, Kubátová A. Determination of lignans in flaxseed using liquid chromatography with time-of-flight mass spectrometry. J Chromatogr A. 2009;1216:217-29.
    • (2009) J Chromatogr A , vol.1216 , pp. 217-229
    • Popova, I.E.1    Hall, C.2    Kubátová, A.3
  • 14
    • 84873737064 scopus 로고    scopus 로고
    • Effect of thermal heating on some lignans in flax seeds, sesame seeds and rye
    • 1:CAS:528:DC%2BC3sXitlansbs%3D
    • Gerstenmeyer E, Reimer S, Berghofer E, Schwartz H, Sontag G. Effect of thermal heating on some lignans in flax seeds, sesame seeds and rye. Food Chem. 2013;138:1847-55.
    • (2013) Food Chem , vol.138 , pp. 1847-1855
    • Gerstenmeyer, E.1    Reimer, S.2    Berghofer, E.3    Schwartz, H.4    Sontag, G.5
  • 16
    • 27544451617 scopus 로고    scopus 로고
    • Stability of α-linolenic acid and secoisolariciresinol diglucoside in flaxseed-fortified macaroni
    • Hall CA, Manthey FA, Lee RE, Niehaus M. Stability of α-linolenic acid and secoisolariciresinol diglucoside in flaxseed-fortified macaroni. J Food Sci. 2005;70:483-9.
    • (2005) J Food Sci , vol.70 , pp. 483-489
    • Hall, C.A.1    Manthey, F.A.2    Lee, R.E.3    Niehaus, M.4
  • 17
    • 0033805346 scopus 로고    scopus 로고
    • Quantitation of the lignan secoisolariciresinol diglucoside in baked goods containing flax seed or flax meal
    • 1:CAS:528:DC%2BD3cXlslWksbg%3D
    • Muir AD, Westcott ND. Quantitation of the lignan secoisolariciresinol diglucoside in baked goods containing flax seed or flax meal. J Agric Food Chem. 2000;48:4048-52.
    • (2000) J Agric Food Chem , vol.48 , pp. 4048-4052
    • Muir, A.D.1    Westcott, N.D.2
  • 20
    • 84896377923 scopus 로고    scopus 로고
    • Effect of ethanolic flax (Linum usitatissimum L.) extracts on lipid oxidation and changes in nutritive value of frozen-stored meat products
    • Waszkowiak K, Szymandera-Buszka K, Hęs̈ M. Effect of ethanolic flax (Linum usitatissimum L.) extracts on lipid oxidation and changes in nutritive value of frozen-stored meat products. Acta Sci Pol Technol Aliment. 2014;13:135-44.
    • (2014) Acta Sci Pol Technol Aliment , vol.13 , pp. 135-144
    • Waszkowiak, K.1    Szymandera-Buszka, K.2    Hęs̈, M.3
  • 21
    • 0019395189 scopus 로고
    • The excretion of lignans in rats-evidence for an intestinal bacterial source for this new group of compounds
    • 1:CAS:528:DyaL3MXktl2ks70%3D
    • Axelson M, Setchell KD. The excretion of lignans in rats-evidence for an intestinal bacterial source for this new group of compounds. FEBS Lett. 1981;123:337-42.
    • (1981) FEBS Lett , vol.123 , pp. 337-342
    • Axelson, M.1    Setchell, K.D.2
  • 23
    • 84857651849 scopus 로고    scopus 로고
    • Plant and mammalian lignans: A review of source, intake, metabolism, intestinal bacteria and health
    • 1:CAS:528:DC%2BC38XjsVWgtL0%3D
    • Landete JM. Plant and mammalian lignans: a review of source, intake, metabolism, intestinal bacteria and health. Food Res Int. 2012;46:410-24.
    • (2012) Food Res Int , vol.46 , pp. 410-424
    • Landete, J.M.1
  • 24
    • 35448953285 scopus 로고    scopus 로고
    • Lignans and human health
    • 1:CAS:528:DC%2BD2sXhtFKlsr7K
    • Adlercreutz H. Lignans and human health. Crit Rev Clin Lab Sci. 2007;44:483-525.
    • (2007) Crit Rev Clin Lab Sci , vol.44 , pp. 483-525
    • Adlercreutz, H.1
  • 25
    • 0033005792 scopus 로고    scopus 로고
    • Human metabolism of mammalian lignan precursors in raw and processed flaxseed
    • 1:CAS:528:DyaK1MXhslWntrw%3D
    • Nesbitt PD, Lam Y, Thompson LU. Human metabolism of mammalian lignan precursors in raw and processed flaxseed. Am J Clin Nutr. 1999;69:549-55.
    • (1999) Am J Clin Nutr , vol.69 , pp. 549-555
    • Nesbitt, P.D.1    Lam, Y.2    Thompson, L.U.3
  • 26
    • 78649360374 scopus 로고    scopus 로고
    • Flaxseed lignans source, biosynthesis, metabolism, antioxidant activity, bio-active components, and health benefits
    • Touré A, Xueming X. Flaxseed lignans source, biosynthesis, metabolism, antioxidant activity, bio-active components, and health benefits. Compr Rev Food Sci Food Safety. 2010;9:261-9.
    • (2010) Compr Rev Food Sci Food Safety , vol.9 , pp. 261-269
    • Touré, A.1    Xueming, X.2
  • 27
    • 0029951809 scopus 로고    scopus 로고
    • The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity
    • 1:CAS:528:DyaK28XjvFegu74%3D
    • Jenab M, Thompson LU. The influence of flaxseed and lignans on colon carcinogenesis and beta-glucuronidase activity. Carcinogenesis. 1996;17:1343-8.
    • (1996) Carcinogenesis , vol.17 , pp. 1343-1348
    • Jenab, M.1    Thompson, L.U.2
  • 28
    • 0033013574 scopus 로고    scopus 로고
    • Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice
    • 1:CAS:528:DyaK1MXjs1SjtLc%3D
    • Li D, Yee JA, Thompson LU. Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice. Cancer Lett. 1999;142:91-6.
    • (1999) Cancer Lett , vol.142 , pp. 91-96
    • Li, D.1    Yee, J.A.2    Thompson, L.U.3
  • 29
    • 0742270542 scopus 로고    scopus 로고
    • Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats
    • 1:CAS:528:DC%2BD2cXpvFSrtg%3D%3D
    • Tan KP, Chen J, Ward WE, Thompson LU. Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats. Exp Biol Med (Maywood). 2004;229:147-57.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 147-157
    • Tan, K.P.1    Chen, J.2    Ward, W.E.3    Thompson, L.U.4
  • 30
    • 0032806446 scopus 로고    scopus 로고
    • Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats
    • 1:CAS:528:DC%2BD3cXivFGrtQ%3D%3D
    • Rickard SE, Yuan YV, Chen J, Thompson LU. Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Nutr Cancer. 1999;35:50-7.
    • (1999) Nutr Cancer , vol.35 , pp. 50-57
    • Rickard, S.E.1    Yuan, Y.V.2    Chen, J.3    Thompson, L.U.4
  • 31
    • 0034624313 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor i levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside
    • 1:CAS:528:DC%2BD3cXotVCks74%3D
    • Rickard SE, Yuan YV, Thompson LU. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Lett. 2000;161:47-55.
    • (2000) Cancer Lett , vol.161 , pp. 47-55
    • Rickard, S.E.1    Yuan, Y.V.2    Thompson, L.U.3
  • 32
    • 33847392879 scopus 로고    scopus 로고
    • Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
    • Bergman JM, Thompson LU, Dabrosin C. Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clin Cancer Res. 2007;13:1061-7.
    • (2007) Clin Cancer Res , vol.13 , pp. 1061-1067
    • Bergman, J.M.1    Thompson, L.U.2    Dabrosin, C.3
  • 33
    • 57349104719 scopus 로고    scopus 로고
    • Regulation of zinc transporters by dietary flaxseed lignan in human breast cancer xenografts
    • 1:CAS:528:DC%2BD1cXhsVKjtr3F
    • Zhang LY, Wang XL, Sun DX, Liu XX, Hu XY, Kong F. Regulation of zinc transporters by dietary flaxseed lignan in human breast cancer xenografts. Mol Biol Rep. 2008;35:595-600.
    • (2008) Mol Biol Rep , vol.35 , pp. 595-600
    • Zhang, L.Y.1    Wang, X.L.2    Sun, D.X.3    Liu, X.X.4    Hu, X.Y.5    Kong, F.6
  • 34
    • 0034946423 scopus 로고    scopus 로고
    • Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: Exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features
    • 1:STN:280:DC%2BD3MzptFCrsg%3D%3D
    • Demark-Wahnefried W, Price DT, Polascik TJ, Robertson CN, Anderson EE, Paulson DF, et al. Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. Urology. 2001;58:47-52.
    • (2001) Urology , vol.58 , pp. 47-52
    • Demark-Wahnefried, W.1    Price, D.T.2    Polascik, T.J.3    Robertson, C.N.4    Anderson, E.E.5    Paulson, D.F.6
  • 36
    • 0346996531 scopus 로고    scopus 로고
    • Serum enterolactone levels and the risk of breast cancer in women with palpable cysts
    • 1:CAS:528:DC%2BD3sXpvVWht7w%3D
    • Boccardo F, Lunardi G, Guglielmini P. Serum enterolactone levels and the risk of breast cancer in women with palpable cysts. Eur J Cancer. 2004;40:84-9.
    • (2004) Eur J Cancer , vol.40 , pp. 84-89
    • Boccardo, F.1    Lunardi, G.2    Guglielmini, P.3
  • 37
    • 0034906003 scopus 로고    scopus 로고
    • Serum enterolactone and risk of breast cancer: A case-control study in eastern Finland
    • 1:CAS:528:DC%2BD3MXjvVaqu7o%3D
    • Pietinen P, Stumpf K, Mannisto S. Serum enterolactone and risk of breast cancer: a case-control study in eastern Finland. Cancer Epidemiol Biomarkers Prev. 2001;10:339-44.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 339-344
    • Pietinen, P.1    Stumpf, K.2    Mannisto, S.3
  • 38
    • 68149137606 scopus 로고    scopus 로고
    • Primary and secondary prevention of cardiovascular diseases: A practical evidence-based approach
    • O'Keefe JH, Carter MD, Lavie CJ. Primary and secondary prevention of cardiovascular diseases: a practical evidence-based approach. Mayo Clin Proc. 2009;84:741-57.
    • (2009) Mayo Clin Proc , vol.84 , pp. 741-757
    • O'Keefe, J.H.1    Carter, M.D.2    Lavie, C.J.3
  • 39
    • 64849088450 scopus 로고    scopus 로고
    • Visceral obesity: The link among inflammation, hypertension, and cardiovascular disease
    • 1:CAS:528:DC%2BD1MXivVemtr4%3D
    • Mathieu P, Poirier P, Pibarot P. Visceral obesity: the link among inflammation, hypertension, and cardiovascular disease. Hypertension. 2009;53:577-84.
    • (2009) Hypertension , vol.53 , pp. 577-584
    • Mathieu, P.1    Poirier, P.2    Pibarot, P.3
  • 40
    • 84906046678 scopus 로고    scopus 로고
    • Isolation, characterization and antihyperlipidemic activity of secoisolariciresinol diglucoside in poloxamer-407-induced experimental hyperlipidemia
    • 1:CAS:528:DC%2BC2cXhtl2hs7fJ
    • Zanwar AA, Hegde MV, Rojatkar SR, Sonawane KB, Rajamohanan PR, Bodhankar SL. Isolation, characterization and antihyperlipidemic activity of secoisolariciresinol diglucoside in poloxamer-407-induced experimental hyperlipidemia. Pharm Biol. 2014;52:1094-103.
    • (2014) Pharm Biol , vol.52 , pp. 1094-1103
    • Zanwar, A.A.1    Hegde, M.V.2    Rojatkar, S.R.3    Sonawane, K.B.4    Rajamohanan, P.R.5    Bodhankar, S.L.6
  • 41
    • 0037467079 scopus 로고    scopus 로고
    • Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds
    • 1:CAS:528:DC%2BD3sXmt1yhtw%3D%3D
    • Sicilia T, Niemeyer HB, Honig DM, Metzler M. Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds. J Agric Food Chem. 2003;51:1181-8.
    • (2003) J Agric Food Chem , vol.51 , pp. 1181-1188
    • Sicilia, T.1    Niemeyer, H.B.2    Honig, D.M.3    Metzler, M.4
  • 42
    • 45549104369 scopus 로고    scopus 로고
    • Dietary flaxseed lignin extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects
    • 1:CAS:528:DC%2BD1cXmtFakurc%3D
    • Zhang W, Wang X, Liu Y. Dietary flaxseed lignin extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects. Br J Nutr. 2008;99:1301-9.
    • (2008) Br J Nutr , vol.99 , pp. 1301-1309
    • Zhang, W.1    Wang, X.2    Liu, Y.3
  • 43
    • 77951234112 scopus 로고    scopus 로고
    • Health effects with consumption of the flax lignin secoisolariciresinol diglucoside
    • 1:CAS:528:DC%2BC3cXktlequrg%3D
    • Adolphe JL, Whiting SJ, Juurlink BHJ, Thorpe LU, Alcorn J. Health effects with consumption of the flax lignin secoisolariciresinol diglucoside. British J Nutr. 2010;103:929-38.
    • (2010) British J Nutr , vol.103 , pp. 929-938
    • Adolphe, J.L.1    Whiting, S.J.2    Juurlink, B.H.J.3    Thorpe, L.U.4    Alcorn, J.5
  • 44
    • 66149109977 scopus 로고    scopus 로고
    • A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults
    • 1:CAS:528:DC%2BD1MXksVyitbg%3D
    • Cornish SM, Chilibeck PD, Paus-Jennsen L. A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults. Appl Physiol Nutr Metab. 2009;34:89-98.
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 89-98
    • Cornish, S.M.1    Chilibeck, P.D.2    Paus-Jennsen, L.3
  • 45
    • 49649121328 scopus 로고    scopus 로고
    • Flaxseed lignin attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice
    • 1:CAS:528:DC%2BD1cXht1Snt7zJ
    • Fukumitsu S, Aida K, Ueno N. Flaxseed lignin attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice. Br J Nutr. 2008;100:669-76.
    • (2008) Br J Nutr , vol.100 , pp. 669-676
    • Fukumitsu, S.1    Aida, K.2    Ueno, N.3
  • 46
    • 0034956076 scopus 로고    scopus 로고
    • Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat
    • 1:CAS:528:DC%2BD3MXlsFShur0%3D
    • Prasad K. Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. J Lab Clin Med. 2001;138:32-9.
    • (2001) J Lab Clin Med , vol.138 , pp. 32-39
    • Prasad, K.1
  • 47
    • 61449102645 scopus 로고    scopus 로고
    • Flax lignan complex slows down the progression of atherosclerosis in hyperlipidemic rabbits
    • 1:CAS:528:DC%2BD1MXjsValur4%3D
    • Prasad K. Flax lignan complex slows down the progression of atherosclerosis in hyperlipidemic rabbits. J Cardiovasc Pharmacol Ther. 2009;14:38-48.
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 38-48
    • Prasad, K.1
  • 48
    • 37249017171 scopus 로고    scopus 로고
    • A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex
    • 1:CAS:528:DC%2BD2sXhsVKjsr7F
    • Prasad K. A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex. J Cardiovasc Pharmacol Ther. 2007;12:304-13.
    • (2007) J Cardiovasc Pharmacol Ther , vol.12 , pp. 304-313
    • Prasad, K.1
  • 51
    • 34547666796 scopus 로고    scopus 로고
    • A review of the interaction among dietary antioxidants and reactive oxygen species
    • 1:CAS:528:DC%2BD2sXovFOrsbg%3D
    • Seifried HE, Anderson DE, Fisher EI, Milner JA. A review of the interaction among dietary antioxidants and reactive oxygen species. J Nutr Biochem. 2007;18:567-79.
    • (2007) J Nutr Biochem , vol.18 , pp. 567-579
    • Seifried, H.E.1    Anderson, D.E.2    Fisher, E.I.3    Milner, J.A.4
  • 52
    • 85018138851 scopus 로고    scopus 로고
    • Hepatoprotective activity of lignan compound from flaxseed (linumusitatissimum l.) against acetaminopheninduced hepatotoxicity in rabbits
    • Al-Jumaily EF, AL-Azawi AH. Hepatoprotective activity of lignan compound from flaxseed (linumusitatissimum l.) against acetaminopheninduced hepatotoxicity in rabbits. World J Pharma Pharmaceut Sci. 2013;3:56-72.
    • (2013) World J Pharma Pharmaceut Sci , vol.3 , pp. 56-72
    • Al-Jumaily, E.F.1    AL-Azawi, A.H.2
  • 53
    • 0037390165 scopus 로고    scopus 로고
    • Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and steatosis of the liver in an animal model of obesity
    • Bhathena S, Ali A, Haudenschild C, Latham P, Ranich T, Mohamed A. Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and steatosis of the liver in an animal model of obesity. J American College Nutri. 2002;22:157-64.
    • (2002) J American College Nutri , vol.22 , pp. 157-164
    • Bhathena, S.1    Ali, A.2    Haudenschild, C.3    Latham, P.4    Ranich, T.5    Mohamed, A.6
  • 54
    • 84938414586 scopus 로고    scopus 로고
    • Evaluation of flaxseed effects on non-alcoholic fatty liver disease (NAFLD) in rabbits submitted to a hypercholesterolemic diet
    • 1:CAS:528:DC%2BC2MXotFWrsg%3D%3D
    • Saad CT, Précoma DB, Merlini AB, Ioshii SO, Champoski AF. Evaluation of flaxseed effects on non-alcoholic fatty liver disease (NAFLD) in rabbits submitted to a hypercholesterolemic diet. Funct Foods Health Dis. 2014;4:442-50.
    • (2014) Funct Foods Health Dis , vol.4 , pp. 442-450
    • Saad, C.T.1    Précoma, D.B.2    Merlini, A.B.3    Ioshii, S.O.4    Champoski, A.F.5
  • 55
    • 77955936575 scopus 로고    scopus 로고
    • Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men
    • 1:CAS:528:DC%2BC3cXhtV2hurzP
    • Fukumitsu S, Aida K, Shimizu H, Toyoda K. Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men. Nutr Res. 2010;30:441-6.
    • (2010) Nutr Res , vol.30 , pp. 441-446
    • Fukumitsu, S.1    Aida, K.2    Shimizu, H.3    Toyoda, K.4
  • 56
    • 0033916052 scopus 로고    scopus 로고
    • A novel treatment for lupus nephritis: Lignan precursor derived from flax
    • 1:CAS:528:DC%2BD3cXlvF2jtLs%3D
    • Clark WF, Muir AD, Westcott ND, Parbtani A. A novel treatment for lupus nephritis: lignan precursor derived from flax. Lupus. 2000;9:429-36.
    • (2000) Lupus , vol.9 , pp. 429-436
    • Clark, W.F.1    Muir, A.D.2    Westcott, N.D.3    Parbtani, A.4
  • 57
    • 0035844065 scopus 로고    scopus 로고
    • Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats
    • 1:CAS:528:DC%2BD3MXjsVarsrs%3D
    • Ward WE, Yuan YV, Cheung AM, Thompson LU. Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats. J Toxicol Environ Health A. 2001;63:53-65.
    • (2001) J Toxicol Environ Health A , vol.63 , pp. 53-65
    • Ward, W.E.1    Yuan, Y.V.2    Cheung, A.M.3    Thompson, L.U.4
  • 58
    • 0034767830 scopus 로고    scopus 로고
    • Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats
    • 1:CAS:528:DC%2BD3MXotFGqsLw%3D
    • Ward WE, Yuan YV, Cheung AM, Thompson LU. Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats. Br J Nutr. 2001;86:499-505.
    • (2001) Br J Nutr , vol.86 , pp. 499-505
    • Ward, W.E.1    Yuan, Y.V.2    Cheung, A.M.3    Thompson, L.U.4
  • 59
    • 67649884790 scopus 로고    scopus 로고
    • Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats
    • Sacco SM, Jiang JM, Reza-López S, Ma DW, Thompson LU, Ward WE. Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats. Menopause. 2009;16:545-54.
    • (2009) Menopause , vol.16 , pp. 545-554
    • Sacco, S.M.1    Jiang, J.M.2    Reza-López, S.3    Ma, D.W.4    Thompson, L.U.5    Ward, W.E.6
  • 60
    • 33846200824 scopus 로고    scopus 로고
    • Effects of flaxseed derivatives in experimental polycystic kidney disease vary with animal gender
    • 1:CAS:528:DC%2BD2sXmvVyqsg%3D%3D
    • Ogborn MR, Nitschmann E, Bankovic-Calic N, Weiler HA, Aukema HM. Effects of flaxseed derivatives in experimental polycystic kidney disease vary with animal gender. Lipids. 2006;41:1141-9.
    • (2006) Lipids , vol.41 , pp. 1141-1149
    • Ogborn, M.R.1    Nitschmann, E.2    Bankovic-Calic, N.3    Weiler, H.A.4    Aukema, H.M.5
  • 61
    • 0032513184 scopus 로고    scopus 로고
    • Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats
    • 1:CAS:528:DyaK1cXhtVWhsLc%3D
    • Orcheson LJ, Rickard SE, Seidl MM, Thompson LU. Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats. Cancer Lett. 1998;125:69-76.
    • (1998) Cancer Lett , vol.125 , pp. 69-76
    • Orcheson, L.J.1    Rickard, S.E.2    Seidl, M.M.3    Thompson, L.U.4
  • 62
    • 66149084407 scopus 로고    scopus 로고
    • Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury
    • 1:CAS:528:DC%2BD1MXptVenur4%3D
    • Lee JC, Krochak R, Blouin A, Kanterakis S, Chatterjee S, Arguiri E, et al. Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury. Cancer Biol Ther. 2009;8:47-53.
    • (2009) Cancer Biol Ther , vol.8 , pp. 47-53
    • Lee, J.C.1    Krochak, R.2    Blouin, A.3    Kanterakis, S.4    Chatterjee, S.5    Arguiri, E.6
  • 63
    • 33748320970 scopus 로고    scopus 로고
    • Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women
    • 1:CAS:528:DC%2BD28Xpt1Wju70%3D
    • Hallund J, Tetens I, Bügel S, Tholstrup T, Ferrari M, Teerlink T, et al. Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women. J Nutr. 2006;136:2314-8.
    • (2006) J Nutr , vol.136 , pp. 2314-2318
    • Hallund, J.1    Tetens, I.2    Bügel, S.3    Tholstrup, T.4    Ferrari, M.5    Teerlink, T.6
  • 64
    • 46749104505 scopus 로고    scopus 로고
    • Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia
    • 1:CAS:528:DC%2BD1cXotVCjsL4%3D
    • Zhang W, Wang X, Liu Y, Tian H, Flickinger B, Empie MW, et al. Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia. J Med Food. 2008;11:207-14.
    • (2008) J Med Food , vol.11 , pp. 207-214
    • Zhang, W.1    Wang, X.2    Liu, Y.3    Tian, H.4    Flickinger, B.5    Empie, M.W.6
  • 65
    • 0033858991 scopus 로고    scopus 로고
    • Urinary composition and postprandial blood changes in H-secoisolariciresinol diglycoside (SDG) metabolites in rats do not differ between acute and chronic SDG treatments
    • 1:CAS:528:DC%2BD3cXmsVWksro%3D
    • Rickard SE, Thompson LU. Urinary composition and postprandial blood changes in H-secoisolariciresinol diglycoside (SDG) metabolites in rats do not differ between acute and chronic SDG treatments. J Nutr. 2000;130:2299-305.
    • (2000) J Nutr , vol.130 , pp. 2299-2305
    • Rickard, S.E.1    Thompson, L.U.2
  • 66
    • 0035824381 scopus 로고    scopus 로고
    • Exposure to flaxseed or its purified lignan during suckling only or continuously does not alter reproductive indices in male and female offspring
    • 1:CAS:528:DC%2BD3MXptVagu7k%3D
    • Ward WE, Chen J, Thompson LU. Exposure to flaxseed or its purified lignan during suckling only or continuously does not alter reproductive indices in male and female offspring. J Toxicol Environ Health A. 2001;64:567-77.
    • (2001) J Toxicol Environ Health A , vol.64 , pp. 567-577
    • Ward, W.E.1    Chen, J.2    Thompson, L.U.3
  • 67
    • 0031737636 scopus 로고    scopus 로고
    • Flaxseed and its lignan precursor, secoisolariciresinol diglycoside, affect pregnancy outcome and reproductive development in rats
    • 1:CAS:528:DyaK1cXntF2ksb4%3D
    • Tou JC, Chen J, Thompson LU. Flaxseed and its lignan precursor, secoisolariciresinol diglycoside, affect pregnancy outcome and reproductive development in rats. J Nutr. 1998;128:1861-8.
    • (1998) J Nutr , vol.128 , pp. 1861-1868
    • Tou, J.C.1    Chen, J.2    Thompson, L.U.3
  • 68
    • 0347517830 scopus 로고    scopus 로고
    • The effect of flax seed cultivars with differing content of alpha-linolenic acid and lignans on responses to mental stress
    • Spence JD, Thornton T, Muir AD, Westcott ND. The effect of flax seed cultivars with differing content of alpha-linolenic acid and lignans on responses to mental stress. J Am Coll Nutr. 2003;22:494-501.
    • (2003) J Am Coll Nutr , vol.22 , pp. 494-501
    • Spence, J.D.1    Thornton, T.2    Muir, A.D.3    Westcott, N.D.4
  • 69
    • 84873409151 scopus 로고    scopus 로고
    • Antidepressant-like effect of flaxseed secoisolariciresinol diglycoside in ovariectomized mice subjected to unpredictable chronic stress
    • Ma X, Wang R, Zhao X, Zhang C, Sun J, Li J, et al. Antidepressant-like effect of flaxseed secoisolariciresinol diglycoside in ovariectomized mice subjected to unpredictable chronic stress. Metab Brain Dis. 2013;28:77-84.
    • (2013) Metab Brain Dis , vol.28 , pp. 77-84
    • Ma, X.1    Wang, R.2    Zhao, X.3    Zhang, C.4    Sun, J.5    Li, J.6
  • 70
    • 85018148770 scopus 로고    scopus 로고
    • Effects of flaxseed lignan on mitogen stimulated lymphocyte proliferation
    • Rhee Y, Brunt A. Effects of flaxseed lignan on mitogen stimulated lymphocyte proliferation. FASEB J. 2007;21:702-11.
    • (2007) FASEB J , vol.21 , pp. 702-711
    • Rhee, Y.1    Brunt, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.