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Volumn 14, Issue 1, 2009, Pages 38-48

Flax lignan complex slows down the progression of atherosclerosis in hyperlipidemic rabbits

Author keywords

Antioxidant reserve; Flax lignan complex; Hypercholesterolemia; Malondialdehyde; Oxygen radicals; Slowing of progression of atherosclerosis; White blood cell chemiluminescence

Indexed keywords

ANTIOXIDANT; FLAX LIGNAN COMPLEX; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; UNCLASSIFIED DRUG;

EID: 61449102645     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/1074248408330541     Document Type: Article
Times cited : (42)

References (46)
  • 1
    • 0033574164 scopus 로고    scopus 로고
    • Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed
    • Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation. 1999; 99: 1355-1362.
    • (1999) Circulation , vol.99 , pp. 1355-1362
    • Prasad, K.1
  • 2
    • 14944371679 scopus 로고    scopus 로고
    • Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed
    • Prasad K. Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed. Atherosclerosis. 2005; 179: 269-275.
    • (2005) Atherosclerosis , vol.179 , pp. 269-275
    • Prasad, K.1
  • 3
    • 0027474868 scopus 로고
    • Oxygen free radicals and hypercholesterolemic atherosclerosis: Effect of vitamin e
    • Prasad K., Kalra J. Oxygen free radicals and hypercholesterolemic atherosclerosis: effect of vitamin E. Am Heart J. 1993; 125: 958-973.
    • (1993) Am Heart J , vol.125 , pp. 958-973
    • Prasad, K.1    Kalra, J.2
  • 4
    • 34248199903 scopus 로고    scopus 로고
    • Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism
    • Prasad K., Lee P. Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism. Atherosclerosis. 2007; 192: 313-322.
    • (2007) Atherosclerosis , vol.192 , pp. 313-322
    • Prasad, K.1    Lee, P.2
  • 5
    • 0026874975 scopus 로고
    • Antioxidants in the prevention of human atherosclerosis
    • Steinberg D. Antioxidants in the prevention of human atherosclerosis. Circulation. 1992; 85: 2337-2344.
    • (1992) Circulation , vol.85 , pp. 2337-2344
    • Steinberg, D.1
  • 6
    • 0141455921 scopus 로고    scopus 로고
    • Suppression of oxidative stress as a mechanism of reduction of hypercholesterolemic atherosclerosis by cyclooxygenase inhibitors
    • Lee P., Prasad K. Suppression of oxidative stress as a mechanism of reduction of hypercholesterolemic atherosclerosis by cyclooxygenase inhibitors. Int J Angiol. 2003; 12: 13-23.
    • (2003) Int J Angiol , vol.12 , pp. 13-23
    • Lee, P.1    Prasad, K.2
  • 7
    • 0002133777 scopus 로고
    • Oxygen free radicals as a mechanism of hypercholesterolemic atherosclerosis: Effects of probucol
    • Prasad K., Kalra J., Lee P. Oxygen free radicals as a mechanism of hypercholesterolemic atherosclerosis: effects of probucol. Int J Angiol. 1994; 3: 10-12.
    • (1994) Int J Angiol , vol.3 , pp. 10-12
    • Prasad, K.1    Kalra, J.2    Lee, P.3
  • 9
    • 0031040390 scopus 로고    scopus 로고
    • Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flaxseed
    • Prasad K. Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flaxseed. Mol Cell Biochem. 1997; 168: 117-123.
    • (1997) Mol Cell Biochem , vol.168 , pp. 117-123
    • Prasad, K.1
  • 10
    • 0033758487 scopus 로고    scopus 로고
    • Antioxidant activity of secoisolariciresinol diglucoside-derived metabolites, secoisolariciresinol, enterodiol, and enterolactone
    • Prasad K. Antioxidant activity of secoisolariciresinol diglucoside-derived metabolites, secoisolariciresinol, enterodiol, and enterolactone. Int J Angiol. 2000; 9: 220-225.
    • (2000) Int J Angiol , vol.9 , pp. 220-225
    • Prasad, K.1
  • 11
    • 0001759538 scopus 로고    scopus 로고
    • Flavonoids, coumarins, and cinnamic acids as antioxidants in a micellar system: Structure-activity relationship
    • Foti M., Piatelli M., Baratta MT Flavonoids, coumarins, and cinnamic acids as antioxidants in a micellar system: structure-activity relationship. J Agric Food Chem. 1996 ; 44: 497-501.
    • (1996) J Agric Food Chem , vol.44 , pp. 497-501
    • Foti, M.1    Piatelli, M.2    Baratta, M.T.3
  • 12
    • 0025735365 scopus 로고
    • The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidemic rabbits
    • Daugherty A., Zweifel BS, Schonfeld G. The effects of probucol on the progression of atherosclerosis in mature Watanabe heritable hyperlipidemic rabbits. Br J Pharmacol. 1991; 103: 1013-1018.
    • (1991) Br J Pharmacol , vol.103 , pp. 1013-1018
    • Daugherty, A.1    Zweifel, B.S.2    Schonfeld, G.3
  • 13
    • 0023392413 scopus 로고
    • Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia
    • Kita T., Nagano Y., Yokode M., et al. Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci USA. 1987; 84: 5928-5931.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5928-5931
    • Kita, T.1    Nagano, Y.2    Yokode, M.3
  • 14
    • 0035143930 scopus 로고    scopus 로고
    • Does therapeutic intervention achieve slowing of progression or bona fide regression of atherosclerotic lesions
    • Stein Y., Stein O. Does therapeutic intervention achieve slowing of progression or bona fide regression of atherosclerotic lesions ? Arterioscler Thromb Vasc Biol. 2001; 21: 183-188.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 183-188
    • Stein, Y.1    Stein, O.2
  • 15
    • 0037215872 scopus 로고    scopus 로고
    • Effects of amlodipine, atorvastatin and combination of both on advanced atherosclerotic plaque in APOE*3-Leiden transgenic mice
    • van de Poll SW, Delsing DJ, Wouter Jukema J., et al. Effects of amlodipine, atorvastatin and combination of both on advanced atherosclerotic plaque in APOE*3-Leiden transgenic mice. J Mol Coll Cardiol. 2003; 35: 109-118.
    • (2003) J Mol Coll Cardiol , vol.35 , pp. 109-118
    • Van De Poll, S.W.1    Delsing, D.J.2    Wouter Jukema, J.3
  • 16
    • 0027995530 scopus 로고
    • Role of oxyradicals in cardiovascular depression and cellular injury in hemorrhagic shock and reinfusion: Effect of SOD and catalase
    • Kapoor R., Prasad K. Role of oxyradicals in cardiovascular depression and cellular injury in hemorrhagic shock and reinfusion: effect of SOD and catalase. Circ Shock. 1994; 43: 79-94.
    • (1994) Circ Shock , vol.43 , pp. 79-94
    • Kapoor, R.1    Prasad, K.2
  • 17
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal Biochem. 1979; 95: 351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 18
    • 70449176070 scopus 로고
    • Techniques for studying atherosclerotic lesions
    • Holman RL, McGill HC Jr, Strong JP, Geer JC Techniques for studying atherosclerotic lesions. Lab Invest. 1958; 7: 42-47.
    • (1958) Lab Invest , vol.7 , pp. 42-47
    • Holman, R.L.1    Jr M.Hc2    Strong, J.P.3    Geer, J.C.4
  • 19
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of biuret reaction
    • Gornall AG, Bardawill CJ, David MM Determination of serum proteins by means of biuret reaction. J Biol Chem. 1949; 177: 751-766.
    • (1949) J Biol Chem , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawill, C.J.2    David, M.M.3
  • 20
    • 0026548516 scopus 로고
    • Effect of lovastatin on suppression and regression of atherosclerosis in lipid-fed rabbits
    • Zhu BQ, Sievers RE, Sun YP, Iconberg WM, Parmley WW Effect of lovastatin on suppression and regression of atherosclerosis in lipid-fed rabbits. J Cardiovasc Pharmacol. 1992; 19: 246-255.
    • (1992) J Cardiovasc Pharmacol , vol.19 , pp. 246-255
    • Zhu, B.Q.1    Sievers, R.E.2    Sun, Y.P.3    Iconberg, W.M.4    Parmley, W.W.5
  • 21
    • 0028605934 scopus 로고
    • Effects of etidronate and lovastatin on the regression of atherosclerosis in cholesterol-fed rabbits
    • Zhu BQ, Sun YP, Sievers RE, Isenberg WM, Moorehead TJ, Parmley WW Effects of etidronate and lovastatin on the regression of atherosclerosis in cholesterol-fed rabbits. Cardiology. 1994; 85: 370-377.
    • (1994) Cardiology , vol.85 , pp. 370-377
    • Zhu, B.Q.1    Sun, Y.P.2    Sievers, R.E.3    Isenberg, W.M.4    Moorehead, T.J.5    Parmley, W.W.6
  • 22
    • 0033532524 scopus 로고    scopus 로고
    • A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: Possible relevance of up-regulation of endothelial NO synthase mRNA
    • Kano H., Hayashi T., Sumi D., et al. A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA. Biochem Biophys Res Commun. 1999; 259: 414-419.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 414-419
    • Kano, H.1    Hayashi, T.2    Sumi, D.3
  • 23
    • 0029123175 scopus 로고
    • Development and progression of atherosclerosis in aorta from heterozygous and homozygous WHHL rabbits: Effects of simvastatin treatment
    • Dowell FJ, Hamilton CA, Lindop GB, Reid JL Development and progression of atherosclerosis in aorta from heterozygous and homozygous WHHL rabbits: effects of simvastatin treatment. Arterioscler Thromb Vasc Biol. 1995; 15: 1152-1160.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1152-1160
    • Dowell, F.J.1    Hamilton, C.A.2    Lindop, G.B.3    Reid, J.L.4
  • 24
    • 0025923658 scopus 로고
    • Effects of simvastatin on serum lipids and atherosclerosis in WHHL rabbits
    • Fukuo Y., Nagashima M., Saitoh A., et al. Effects of simvastatin on serum lipids and atherosclerosis in WHHL rabbits. Clin Ther. 1991; 13: 417-424.
    • (1991) Clin Ther , vol.13 , pp. 417-424
    • Fukuo, Y.1    Nagashima, M.2    Saitoh, A.3
  • 25
    • 0037031061 scopus 로고    scopus 로고
    • Collaborative group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002; 360: 7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
    • Protection Study, H.1
  • 26
    • 33749543120 scopus 로고    scopus 로고
    • Pathophysiology of atherosclerosis
    • Chang JB, Olsen ER, Prasad K, Sumpio BE, eds. New York, NY: Springer;
    • Prasad K. Pathophysiology of atherosclerosis. In: Chang JB, Olsen ER, Prasad K, Sumpio BE, eds. Textbook of Angiology. New York, NY: Springer; 2000: 85-105.
    • (2000) Textbook of Angiology , pp. 85-105
    • Prasad, K.1
  • 27
  • 28
    • 0027199071 scopus 로고
    • Antioxidant enzymes in hypercholesterolemia and effects of vitamin e in rabbits
    • Mantha SV, Prasad M., Kalra J., Prasad K. Antioxidant enzymes in hypercholesterolemia and effects of vitamin E in rabbits. Atherosclerosis. 1993; 101: 135-144.
    • (1993) Atherosclerosis , vol.101 , pp. 135-144
    • Mantha, S.V.1    Prasad, M.2    Kalra, J.3    Prasad, K.4
  • 31
    • 0022763360 scopus 로고
    • Oxidative injury to the vascular endothelium
    • Warren JS, Ward PA Oxidative injury to the vascular endothelium. Am J Med Sci. 1986; 292: 97-103.
    • (1986) Am J Med Sci , vol.292 , pp. 97-103
    • Warren, J.S.1    Ward, P.A.2
  • 32
    • 0030944506 scopus 로고    scopus 로고
    • Vitamin e inhibits low density lipoprotein-induced adhesion of monocytes to human aortic endothelial cells in vitro
    • Martin A., Foxall T., Blumberg JB, Meydani M. Vitamin E inhibits low density lipoprotein-induced adhesion of monocytes to human aortic endothelial cells in vitro. Arterioscler Thromb Vasc Biol. 1997; 17: 429-436.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 429-436
    • Martin, A.1    Foxall, T.2    Blumberg, J.B.3    Meydani, M.4
  • 33
    • 0031458094 scopus 로고    scopus 로고
    • Reactive oxygen species are involved in shear stress-induced intracellular adhesion molecule-1 expression in endothelial cells
    • Chiu JJ, Wung BS, Shyy JY, Hsieh HJ, Wang DL Reactive oxygen species are involved in shear stress-induced intracellular adhesion molecule-1 expression in endothelial cells. Arterioscler Thromb Vasc Biol. 1997; 17: 3570-3577.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3570-3577
    • Chiu, J.J.1    Wung, B.S.2    Shyy, J.Y.3    Hsieh, H.J.4    Wang, D.L.5
  • 34
    • 0025281588 scopus 로고
    • Minimally modified low density lipoprotein induces monocyte chemotactic protein-1 in human endothelial cells and smooth muscle cells
    • Cushing SD, Berliner JA, Valente AJ, et al. Minimally modified low density lipoprotein induces monocyte chemotactic protein-1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA. 1990; 87: 5134-5138.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5134-5138
    • Cushing, S.D.1    Berliner, J.A.2    Valente, A.J.3
  • 35
    • 10544246489 scopus 로고    scopus 로고
    • Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
    • Rajagopalan S., Meng XP, Ramasamy S., Harrison DG, Galis ZS Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest. 1996; 98: 2572-2579.
    • (1996) J Clin Invest. , vol.98 , pp. 2572-2579
    • Rajagopalan, S.1    Meng, X.P.2    Ramasamy, S.3    Harrison, D.G.4    Galis, Z.S.5
  • 36
    • 0029124027 scopus 로고
    • Supplementation of hypercholesterolemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
    • Böger RH, Bode-Böger SM, Mügge A., et al. Supplementation of hypercholesterolemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production. Atherosclerosis. 1995; 117: 273-284.
    • (1995) Atherosclerosis , vol.117 , pp. 273-284
    • Böger, R.H.1    Bode-Böger, S.M.2    Mügge, A.3
  • 37
    • 0342378190 scopus 로고    scopus 로고
    • Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin
    • Böger RH, Bode-Böger SM, Brandes RP, et al. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation. 1997; 96: 1282-1290.
    • (1997) Circulation , vol.96 , pp. 1282-1290
    • Böger, R.H.1    Bode-Böger, S.M.2    Brandes, R.P.3
  • 38
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P., Leone A., Calver A., Collier J., Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet. 1992; 339: 572-575.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 40
    • 0022654473 scopus 로고
    • Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbits by treatment with calcium blocker PN 200110
    • Habib JB, Bossaller C., Wells S., Williams C., Morrisett JD, Henry PD Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbits by treatment with calcium blocker PN 200110. Circ Res. 1986; 58: 305-309.
    • (1986) Circ Res , vol.58 , pp. 305-309
    • Habib, J.B.1    Bossaller, C.2    Wells, S.3    Williams, C.4    Morrisett, J.D.5    Henry, P.D.6
  • 41
    • 0028147596 scopus 로고
    • Comparison of the antiatherogenic effects of isradipine and ramipril in cholesterol-fed rabbits, II: Effect on regression of atherosclerosis and restoration of endothelial function
    • Riezebos J., Vleeming W., Beems RB, et al. Comparison of the antiatherogenic effects of isradipine and ramipril in cholesterol-fed rabbits, II: effect on regression of atherosclerosis and restoration of endothelial function. J Cardiovasc Pharmacol. 1994; 23: 424-431.
    • (1994) J Cardiovasc Pharmacol , vol.23 , pp. 424-431
    • Riezebos, J.1    Vleeming, W.2    Beems, R.B.3
  • 42
    • 0029096765 scopus 로고
    • Kuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL-lowering on atherosclerotic progression in carotid and femoral arteries
    • Salonen R., Nyyssönen K., Porkkala E., et al. Kuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL-lowering on atherosclerotic progression in carotid and femoral arteries. Circulation. 1995; 92: 1758-1764.
    • (1995) Circulation. , vol.92 , pp. 1758-1764
    • Salonen, R.1    Nyyssönen, K.2    Porkkala, E.3
  • 43
    • 0038689511 scopus 로고    scopus 로고
    • Effects of long term cholesterol lowering on coronary atherosclerosis in patient risk factor subgroups: The Simvastatin/enalapril Coronary Atherosclerosis Trial (SCAT)
    • Burton JR, Teo KK, Buller CE, et al, and the SCAT investigators. Effects of long term cholesterol lowering on coronary atherosclerosis in patient risk factor subgroups: the Simvastatin/enalapril Coronary Atherosclerosis Trial (SCAT). Can J Cardiol. 2003; 19: 487-491.
    • (2003) Can J Cardiol. , vol.19 , pp. 487-491
    • Burton, J.R.1    Teo, K.K.2    Buller, C.E.3    Investigators, S.4
  • 44
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: A double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • Taylor AJ, Sullenberger LE, Lee HJ, Lee JK, Grace KA Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. Circulation. 2004; 110: 3512-3517.
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3    Lee, J.K.4    Grace, K.A.5
  • 45
    • 12144291640 scopus 로고    scopus 로고
    • The effect of vitamin therapy on the progression of coronary artery atherosclerosis varies by haptoglobin type in postmenopausal women
    • Levy AP, Friedenberg P., Lotan R., et al. The effect of vitamin therapy on the progression of coronary artery atherosclerosis varies by haptoglobin type in postmenopausal women. Diabetes Care. 2004; 27: 925-930.
    • (2004) Diabetes Care , vol.27 , pp. 925-930
    • Levy, A.P.1    Friedenberg, P.2    Lotan, R.3
  • 46
    • 2942659072 scopus 로고    scopus 로고
    • Antihypertensive activity of secoisolariciresinol diglucoside isolated from flaxseed: Role of guanylate cyclase
    • Prasad K. Antihypertensive activity of secoisolariciresinol diglucoside isolated from flaxseed: role of guanylate cyclase. Int J Angiol. 2004; 13: 7-14.
    • (2004) Int J Angiol , vol.13 , pp. 7-14
    • Prasad, K.1


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