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Volumn 35, Issue 1, 1999, Pages 50-57

Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea- induced mammary tumorigenesis in rats

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; LIGNAN; METHYLNITROSOUREA; SECOISOLARICIRESINOL DIGLYCOSIDE; SOYBEAN OIL; UNCLASSIFIED DRUG;

EID: 0032806446     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S1532791450-57     Document Type: Article
Times cited : (60)

References (52)
  • 1
    • 0019395189 scopus 로고
    • The excretion of lignans in rats - Evidence for an intestinal bacterial source for this new group of compounds
    • Axelson, M, and Setchell, KD: The excretion of lignans in rats - evidence for an intestinal bacterial source for this new group of compounds. FEBS Lett 123, 337-342, 1981.
    • (1981) FEBS Lett , vol.123 , pp. 337-342
    • Axelson, M.1    Setchell, K.D.2
  • 3
    • 0019828493 scopus 로고
    • Lignan formation in man - Microbial involvement and possible roles in relation to cancer
    • Setchell, KD, Lawson, AM, Borriello, SP, Harkness, R, Gordon, H, et al.: Lignan formation in man - microbial involvement and possible roles in relation to cancer. Lancet 2, 4-7, 1981.
    • (1981) Lancet , vol.2 , pp. 4-7
    • Setchell, K.D.1    Lawson, A.M.2    Borriello, S.P.3    Harkness, R.4    Gordon, H.5
  • 4
    • 0026569080 scopus 로고
    • Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture
    • Mousavi, Y, and Adlercreutz, H: Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. J Steroid Biochem Mol Biol 41, 615-619, 1992.
    • (1992) J Steroid Biochem Mol Biol , vol.41 , pp. 615-619
    • Mousavi, Y.1    Adlercreutz, H.2
  • 5
    • 0025613733 scopus 로고
    • Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1
    • Hirano, T, Fukuoka, K, Oka, K, Naito, T, Hosaka, K, et al.: Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer Invest 8, 595-602, 1990.
    • (1990) Cancer Invest , vol.8 , pp. 595-602
    • Hirano, T.1    Fukuoka, K.2    Oka, K.3    Naito, T.4    Hosaka, K.5
  • 6
    • 0030880014 scopus 로고    scopus 로고
    • Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells
    • Wang, C, and Kurzer, MS: Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. Nutr Cancer 28, 236-247, 1997.
    • (1997) Nutr Cancer , vol.28 , pp. 236-247
    • Wang, C.1    Kurzer, M.S.2
  • 12
    • 0022553265 scopus 로고
    • Urinary estrogen profile determination in young Finnish vegetarian and omnivorous women
    • Adlercreutz, H, Fotsis, T, Bannwart, C, Hamalainen, E, Bloigu, S, et al.: Urinary estrogen profile determination in young Finnish vegetarian and omnivorous women. Steroid Biochem 24, 289-296, 1986.
    • (1986) Steroid Biochem , vol.24 , pp. 289-296
    • Adlercreutz, H.1    Fotsis, T.2    Bannwart, C.3    Hamalainen, E.4    Bloigu, S.5
  • 13
    • 0022880001 scopus 로고
    • Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens in urine of women on various habitual diets
    • Adlercreutz, H, Fotsis, T, Bannwart, C, Wahala, K, Makela, T, et al.: Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens in urine of women on various habitual diets. J Steroid Biochem 25, 791-797, 1986.
    • (1986) J Steroid Biochem , vol.25 , pp. 791-797
    • Adlercreutz, H.1    Fotsis, T.2    Bannwart, C.3    Wahala, K.4    Makela, T.5
  • 14
    • 0030764023 scopus 로고    scopus 로고
    • Case-control study of phyto-oestrogens and breast cancer
    • Ingram, D, Sanders, K, Kolybaba, M, and Lopez, D: Case-control study of phyto-oestrogens and breast cancer. Lancet 350, 990-994, 1997.
    • (1997) Lancet , vol.350 , pp. 990-994
    • Ingram, D.1    Sanders, K.2    Kolybaba, M.3    Lopez, D.4
  • 15
    • 0016170933 scopus 로고
    • Effect of oral contraceptives on the mammary glands of rhesus monkeys: A prelimi-nary report
    • Drill, VA, Martin, DP, Hart, ER, and McConnell, RG: Effect of oral contraceptives on the mammary glands of rhesus monkeys: a prelimi-nary report. JNCI 52, 1655-1657, 1974.
    • (1974) JNCI , vol.52 , pp. 1655-1657
    • Drill, V.A.1    Martin, D.P.2    Hart, E.R.3    McConnell, R.G.4
  • 16
    • 0344210340 scopus 로고
    • Attempts to produce cancer in rhesus monkeys with carcinogenic hydrocarbons and estrogens
    • Pfeiffer, CA, and Allen, E: Attempts to produce cancer in rhesus monkeys with carcinogenic hydrocarbons and estrogens. Cancer Res 8, 97-127, 1948.
    • (1948) Cancer Res , vol.8 , pp. 97-127
    • Pfeiffer, C.A.1    Allen, E.2
  • 17
    • 84981841935 scopus 로고
    • Mammary response to prolonged estrogenic stimulation in the monkey
    • Geschickter, CF, and Hartman, CG: Mammary response to prolonged estrogenic stimulation in the monkey. Cancer 12, 767-781, 1959.
    • (1959) Cancer , vol.12 , pp. 767-781
    • Geschickter, C.F.1    Hartman, C.G.2
  • 18
    • 0022527745 scopus 로고
    • Identification of lignans and phytoestrogens in urine of chimpanzees
    • Adlercreutz, H, Musey, PI, Fotsis, T, Bannwart, C, Wahala, K, et al.: Identification of lignans and phytoestrogens in urine of chimpanzees. Clin Chim Acta 158, 147-154, 1986.
    • (1986) Clin Chim Acta , vol.158 , pp. 147-154
    • Adlercreutz, H.1    Musey, P.I.2    Fotsis, T.3    Bannwart, C.4    Wahala, K.5
  • 19
    • 0029121370 scopus 로고
    • Effect of diet on lignans and isoflavonoid phytoestrogens in chimpanzees
    • Musey, PI, Adlercreutz, H, Gould, KG, Collins, DC, Fotsis, T, et al.: Effect of diet on lignans and isoflavonoid phytoestrogens in chimpanzees. Life Sci 57, 655-664, 1995.
    • (1995) Life Sci , vol.57 , pp. 655-664
    • Musey, P.I.1    Adlercreutz, H.2    Gould, K.G.3    Collins, D.C.4    Fotsis, T.5
  • 21
    • 0020026453 scopus 로고
    • Origin of lignans in mammals and identification of a precursor from plants
    • Axelson, M. Sjovall, J, Gustafsson, BE, and Setchell, KD: Origin of lignans in mammals and identification of a precursor from plants. Nature 298, 659-660, 1982.
    • (1982) Nature , vol.298 , pp. 659-660
    • Axelson, M.1    Sjovall, J.2    Gustafsson, B.E.3    Setchell, K.D.4
  • 22
    • 0026576476 scopus 로고
    • The effect of flaxseed supplementation on the intiation and promotional stages of mammary tumorigenesis
    • Serraino, M, and Thompson, LU: The effect of flaxseed supplementation on the intiation and promotional stages of mammary tumorigenesis. Nutr Cancer 17, 153-159, 1992.
    • (1992) Nutr Cancer , vol.17 , pp. 153-159
    • Serraino, M.1    Thompson, L.U.2
  • 23
    • 0029902997 scopus 로고    scopus 로고
    • Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis
    • Thompson, LU, Rickard, SE, Orcheson, LJ, and Seidl, MM: Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 17, 1373-1376, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 1373-1376
    • Thompson, L.U.1    Rickard, S.E.2    Orcheson, L.J.3    Seidl, M.M.4
  • 24
    • 0029757978 scopus 로고    scopus 로고
    • Antitumorigenic effect of a mammalian lignan precursor from flaxseed
    • Thompson, LU, Seidl, M, Rickard, S, Orcheson, L, and Fong, H: Antitumorigenic effect of a mammalian lignan precursor from flaxseed. Nutr Cancer 26, 159-165, 1996.
    • (1996) Nutr Cancer , vol.26 , pp. 159-165
    • Thompson, L.U.1    Seidl, M.2    Rickard, S.3    Orcheson, L.4    Fong, H.5
  • 25
    • 0025670466 scopus 로고
    • Effect of dietary α-linolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas
    • Fritsche, KL, and Johnston, PV: Effect of dietary α-linolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas. J Nutr 120, 1601-1609, 1990.
    • (1990) J Nutr , vol.120 , pp. 1601-1609
    • Fritsche, K.L.1    Johnston, P.V.2
  • 26
    • 0016611429 scopus 로고
    • N-nitrosomethylurea as mammary gland carcinogen in rats
    • Gullino, PM, Pettigrew, HM, and Grantham, FH: N-nitrosomethylurea as mammary gland carcinogen in rats. JNCI 54, 401-409, 1975.
    • (1975) JNCI , vol.54 , pp. 401-409
    • Gullino, P.M.1    Pettigrew, H.M.2    Grantham, F.H.3
  • 27
    • 0003616161 scopus 로고
    • Ottawa, ON, Canada: Canadian Council on Animal Care
    • Canadian Council on Animal Care. Guide to the Care and Use of Experimental Animals. Ottawa, ON, Canada: Canadian Council on Animal Care, 1984.
    • (1984) Guide to the Care and Use of Experimental Animals
  • 28
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet
    • Reeves, PG, Nielsen, FH, and Fahey, GC: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951, 1993.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 29
    • 0028938664 scopus 로고
    • Chemical studies of phytoestrogens and related compounds in dietary supplements: Flax and chaparral
    • Obermeyer, WR, Musser, SM, Betz, JM, Casey, RE, Pohland, AE, et al.: Chemical studies of phytoestrogens and related compounds in dietary supplements: flax and chaparral. Proc Soc Exp Biol Med 208, 6-12, 1995.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 6-12
    • Obermeyer, W.R.1    Musser, S.M.2    Betz, J.M.3    Casey, R.E.4    Pohland, A.E.5
  • 30
    • 0002265020 scopus 로고
    • Protocols for screening chemical agents and natural products against animal tumors and other biological systems
    • Geran, RI, Greenberg, NH, Macdonald, MM, Schumacher, AM, and Abbott, BJ: Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother Rep 3, 51-52, 1972.
    • (1972) Cancer Chemother Rep , vol.3 , pp. 51-52
    • Geran, R.I.1    Greenberg, N.H.2    Macdonald, M.M.3    Schumacher, A.M.4    Abbott, B.J.5
  • 31
    • 0000937686 scopus 로고
    • Tests for linear trends in proportions and frequencies
    • Armitage, P: Tests for linear trends in proportions and frequencies. Biometrics 11, 375-386, 1955.
    • (1955) Biometrics , vol.11 , pp. 375-386
    • Armitage, P.1
  • 32
    • 0030507470 scopus 로고    scopus 로고
    • Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones
    • Constantinou, AI, Mehta, RG, and Vaughan, A: Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res 16, 3293-3298, 1996.
    • (1996) Anticancer Res , vol.16 , pp. 3293-3298
    • Constantinou, A.I.1    Mehta, R.G.2    Vaughan, A.3
  • 34
    • 0027954687 scopus 로고
    • Determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatography-mass spectrometry
    • Adlercreutz, H, Fotsis, T, Watanabe, S, Lampe, J, Wahala, K, et al.: Determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatography-mass spectrometry. Cancer Detect Prev 18, 259-271, 1994.
    • (1994) Cancer Detect Prev , vol.18 , pp. 259-271
    • Adlercreutz, H.1    Fotsis, T.2    Watanabe, S.3    Lampe, J.4    Wahala, K.5
  • 35
    • 0025378772 scopus 로고
    • Diet and histologic types of benign breast disease defined by subsequent risk of breast cancer
    • Hislop, TG, Band, PR, Deschamps, M, Ng, V, Coldman, AJ, et al.: Diet and histologic types of benign breast disease defined by subsequent risk of breast cancer. Am J Epidemiol 131, 263-270, 1990.
    • (1990) Am J Epidemiol , vol.131 , pp. 263-270
    • Hislop, T.G.1    Band, P.R.2    Deschamps, M.3    Ng, V.4    Coldman, A.J.5
  • 36
    • 0030900378 scopus 로고    scopus 로고
    • Effects at two years of a low-fat, high-carbohydrate diet on radiologic features of the breast: Results from a randomized trial
    • Boyd, NF, Greenberg, C. Lockwood, G, Little, L, Martin, L, et al.: Effects at two years of a low-fat, high-carbohydrate diet on radiologic features of the breast: results from a randomized trial. JNCI 89, 488-496, 1997.
    • (1997) JNCI , vol.89 , pp. 488-496
    • Boyd, N.F.1    Greenberg, C.2    Lockwood, G.3    Little, L.4    Martin, L.5
  • 37
    • 0010403035 scopus 로고    scopus 로고
    • Beneficial health effects and utilization of flaxseed mucilage and lignans
    • Rickard, SE, and Thompson, LU: Beneficial health effects and utilization of flaxseed mucilage and lignans. Inform 8, 860-865, 1997.
    • (1997) Inform , vol.8 , pp. 860-865
    • Rickard, S.E.1    Thompson, L.U.2
  • 38
    • 0022962322 scopus 로고
    • Chemically-induced mammary gland tumors in rats: Modulation by dietary fat
    • C Ip, DF Birt, AE Rogers, and C Mettlin (eds). New York: Liss
    • Rogers, AE, and Lee, SY: Chemically-induced mammary gland tumors in rats: modulation by dietary fat. In Dietary Fat and Cancer, C Ip, DF Birt, AE Rogers, and C Mettlin (eds). New York: Liss. 1986, pp 255-282.
    • (1986) Dietary Fat and Cancer , pp. 255-282
    • Rogers, A.E.1    Lee, S.Y.2
  • 39
    • 0022595591 scopus 로고
    • Inhibition of chemically induced mammary carcinogenesis in rats by long-term exposure to butylated hydroxytoluene (BHT): Interrelations among BHT concentration, carcinogen dose, and diet
    • Cohen, LA, Choi, K, Numoto, S, Reddy, M, Berke, B, et al.: Inhibition of chemically induced mammary carcinogenesis in rats by long-term exposure to butylated hydroxytoluene (BHT): interrelations among BHT concentration, carcinogen dose, and diet. JNCI 76, 721-730, 1986.
    • (1986) JNCI , vol.76 , pp. 721-730
    • Cohen, L.A.1    Choi, K.2    Numoto, S.3    Reddy, M.4    Berke, B.5
  • 40
    • 0021348250 scopus 로고
    • Inhibition of chemically induced mammary carcinogenesis in rats by short-term exposure to butylated hydroxytoluene (BHT): Interrelationships among BHT concentration, carcinogen dose, and diet
    • Cohen, LA, Polansky, M, Furuya, K, Reddy, M, Berke, B, et al.: Inhibition of chemically induced mammary carcinogenesis in rats by short-term exposure to butylated hydroxytoluene (BHT): interrelationships among BHT concentration, carcinogen dose, and diet JNCI 72, 165-174, 1984.
    • (1984) JNCI , vol.72 , pp. 165-174
    • Cohen, L.A.1    Polansky, M.2    Furuya, K.3    Reddy, M.4    Berke, B.5
  • 41
    • 0017375321 scopus 로고
    • Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies
    • Bien, JG, Stoewsand, GS, Briggs, GM, Phillips, RW, Woodward, JC, et al.: Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 107, 1340-1348, 1977.
    • (1977) J Nutr , vol.107 , pp. 1340-1348
    • Bien, J.G.1    Stoewsand, G.S.2    Briggs, G.M.3    Phillips, R.W.4    Woodward, J.C.5
  • 42
    • 0003979387 scopus 로고
    • Washington, DC: US Government Printing Office
    • US Department of Health, Education, and Welfare: Guidelines for Carcinogen Bioassay of Small Rodents. Washington, DC: US Government Printing Office, 1976.
    • (1976) Guidelines for Carcinogen Bioassay of Small Rodents
  • 43
    • 0020149889 scopus 로고
    • Isoflavone content of soya-based laboratory animal diets
    • Murphy, PA, Farmakalidis, E, and Johnson, LD.: Isoflavone content of soya-based laboratory animal diets. Food Chem Toxicol 20, 315-317, 1982.
    • (1982) Food Chem Toxicol , vol.20 , pp. 315-317
    • Murphy, P.A.1    Farmakalidis, E.2    Johnson, L.D.3
  • 44
    • 0031725466 scopus 로고    scopus 로고
    • A case of laboratory animal feed with high estrogenic activity and its impact on in vivo responses to exogenously administered estrogens
    • Boettger-Tong, H, Murthy, L, Chiappetta, C, Kirkland, JL, Goodwin, B, et al.: A case of laboratory animal feed with high estrogenic activity and its impact on in vivo responses to exogenously administered estrogens. Environ Health Perspect 106, 369-373, 1998.
    • (1998) Environ Health Perspect , vol.106 , pp. 369-373
    • Boettger-Tong, H.1    Murthy, L.2    Chiappetta, C.3    Kirkland, J.L.4    Goodwin, B.5
  • 47
    • 0031935097 scopus 로고    scopus 로고
    • Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats
    • Lamartiniere, CA, Murrill, WB, Manzolillo, PA, Zhang, JX, Barnes, S, et al.: Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats. Proc Soc Exp Biol Med 217, 358-364, 1998.
    • (1998) Proc Soc Exp Biol Med , vol.217 , pp. 358-364
    • Lamartiniere, C.A.1    Murrill, W.B.2    Manzolillo, P.A.3    Zhang, J.X.4    Barnes, S.5
  • 48
    • 0025270351 scopus 로고
    • Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats
    • Hirose, M, Masuda, A, Ito, N, Kamano, K, and Okayama, H: Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats. Carcinogenesis 11, 731-735, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 731-735
    • Hirose, M.1    Masuda, A.2    Ito, N.3    Kamano, K.4    Okayama, H.5
  • 49
    • 0029145260 scopus 로고
    • Protective capability of dietary Zizyphus mistol seed oil, rich in 18:3, n-3, on the development of two murine mammary gland adenocarcinomas with high or low metastatic potential
    • Munoz, SF, Silva, RA, Lamarque, A, Guzman, CA, and Eynard, AR: Protective capability of dietary Zizyphus mistol seed oil, rich in 18:3, n-3, on the development of two murine mammary gland adenocarcinomas with high or low metastatic potential. Prostaglandins Leukot Essent Fatty Acids 53, 135-138, 1995.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.53 , pp. 135-138
    • Munoz, S.F.1    Silva, R.A.2    Lamarque, A.3    Guzman, C.A.4    Eynard, A.R.5
  • 50
    • 0028946787 scopus 로고
    • Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: Relationship to peroxides and vitamin E
    • Chajes, V, Sattler, W, Stranzl, A, and Kostner, GM: Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin E. Breast Cancer Res Treat 34, 199-212, 1995.
    • (1995) Breast Cancer Res Treat , vol.34 , pp. 199-212
    • Chajes, V.1    Sattler, W.2    Stranzl, A.3    Kostner, G.M.4
  • 51
    • 0028017856 scopus 로고
    • n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines
    • Grammatikos, SI, Subbaiah, PV, Victor, TA, and Miller, WM: n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. Br J Cancer 70, 219-227, 1994.
    • (1994) Br J Cancer , vol.70 , pp. 219-227
    • Grammatikos, S.I.1    Subbaiah, P.V.2    Victor, T.A.3    Miller, W.M.4
  • 52
    • 0029020762 scopus 로고
    • The role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma
    • Noguchi, M, Rose, DP, Earashi, M, and Miyazaki, I: The role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma. Oncology 52, 265-271, 1995.
    • (1995) Oncology , vol.52 , pp. 265-271
    • Noguchi, M.1    Rose, D.P.2    Earashi, M.3    Miyazaki, I.4


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