Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/-mice

Aging

Volumn 7, Issue 7, 2015, Pages 500-512

  List, Edward O ^a,b   Berryman, Darlene E ^a,b   Ikeno, Yuji ^c   Hubbard, Gene B ^c   Funk, Kevin ^a   Comisford, Ross ^a   Young, Jonathan A ^a   Stout, Michael B ^d   Tchkonia, Tamar ^d   Masternak, Michal M ^f,g   Bartke, Andrzej ^e   Kirkland, James L ^d   Miller, Richard A ^h   Kopchick, John J ^a  

^a OHIO UNIVERSITY   (United States)

^b OHIO UNIVERSITY   (United States)

^c Mays Cancer Center at UT Health San Antonio   (United States)

^d MAYO CLINIC   (United States)

^e SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^g GREATER POLAND CANCER CENTRE   (Poland)

^h UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Aging; Body composition; Frailty; Growth hormone receptor (GHR); Lifespan; Muscle specific knockout; Pathology

Indexed keywords

C PEPTIDE; CARRIER PROTEIN; GLUCOSE BLOOD LEVEL; INSULIN; SOMATOTROPIN-BINDING PROTEIN;

ANIMAL; BLOOD; BODY COMPOSITION; BODY WEIGHT; ENDURANCE; ENERGY METABOLISM; FEMALE; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HEALTH STATUS; KNOCKOUT MOUSE; LONGEVITY; MALE; METABOLISM; MOUSE; MUSCLE STRENGTH; PHYSIOLOGY; SEXUAL DEVELOPMENT; SKELETAL MUSCLE;

ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; BODY WEIGHT; C-PEPTIDE; CARRIER PROTEINS; ENERGY METABOLISM; FEMALE; GLUCOSE INTOLERANCE; HEALTH STATUS; INSULIN; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; MUSCLE STRENGTH; MUSCLE, SKELETAL; PHYSICAL ENDURANCE; SEX CHARACTERISTICS;

EID: 84938302476     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100766     Document Type: Article

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